Chronic exposure to plasmodium falciparum is associated with phenotypic evidence of b and t cell exhaustion

Journal of Immunology

Volumn 190, Issue 3, 2013, Pages 1038-1047

  Illingworth, Joseph ^a   Butler, Noah S ^a,b   Roetynck, Sophie ^a   Mwacharo, Jedida ^a,b,c   Pierce, Susan K ^a,b   Bejon, Philip ^d,e   Crompton, Peter D ^d   Marsh, Kevin ^d,e   Ndungu, Francis M ^a,b,d,e  

^a KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^e NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD27 ANTIGEN; CD45RA ANTIGEN; LYMPHOCYTE ACTIVATION GENE 3 PROTEIN; PROGRAMMED DEATH 1 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CHILD; CONTROLLED STUDY; ENDEMIC DISEASE; HUMAN; HUMAN CELL; KENYA; LONG TERM EXPOSURE; MALARIA FALCIPARUM; MEMORY CELL; PARASITE TRANSMISSION; PARASITEMIA; PERIPHERAL BLOOD MONONUCLEAR CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; RURAL POPULATION; SCHOOL CHILD; T LYMPHOCYTE; UPREGULATION;

ANIMALS; ANOPHELES; ANTIGENS, CD; ANTIGENS, CD45; APOPTOSIS; B-LYMPHOCYTES; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CHILD; CHILD, PRESCHOOL; ENDEMIC DISEASES; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNITY, INNATE; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INFANT; INFANT, NEWBORN; INSECT BITES AND STINGS; INSECT VECTORS; KENYA; LYMPHOCYTE ACTIVATION; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; PROGRAMMED CELL DEATH 1 RECEPTOR; RURAL POPULATION;

EID: 84872737389     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.120243     Document Type: Article

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