T Cell-Derived IL-10 Determines Leishmaniasis Disease Outcome and Is Suppressed by a Dendritic Cell Based Vaccine

PLoS Pathogens

Volumn 9, Issue 6, 2013, Pages

  Schwarz, Tobias ^a   Remer, Katharina A ^a   Nahrendorf, Wiebke ^a   Masic, Anita ^a   Siewe, Lisa ^b,f   Müller, Werner ^c,d   Roers, Axel ^b,e   Moll, Heidrun ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^f MILTENYI BIOTEC GMBH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; INFLAMMATION; LEISHMANIASIS; MOUSE; NONHUMAN; PARASITE LOAD; T LYMPHOCYTE; TH1 CELL; TH2 CELL; VACCINATION;

ANIMALS; DENDRITIC CELLS; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-4; LEISHMANIA MAJOR; LEISHMANIASIS VACCINES; LEISHMANIASIS, CUTANEOUS; LYMPH NODES; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; TH1 CELLS; TH2 CELLS;

ANIMALIA; LEISHMANIA MAJOR; MURINAE; MUS;

EID: 84879527876     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003476     Document Type: Article

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