-
1
-
-
84862219665
-
Clinical applications of mesenchymal stem cells
-
Wang S., Qu X., Zhao R.C. Clinical applications of mesenchymal stem cells. J. Hematol. Oncol. 2012, 5:19.
-
(2012)
J. Hematol. Oncol.
, vol.5
, pp. 19
-
-
Wang, S.1
Qu, X.2
Zhao, R.C.3
-
2
-
-
84861345298
-
Process engineering of human pluripotent stem cells for clinical application
-
Serra M., Brito C., Correia C., Alves P.M. Process engineering of human pluripotent stem cells for clinical application. Trends Biotechnol. 2012, 30:350-359.
-
(2012)
Trends Biotechnol.
, vol.30
, pp. 350-359
-
-
Serra, M.1
Brito, C.2
Correia, C.3
Alves, P.M.4
-
3
-
-
33747713246
-
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
-
Dominici M., Le Blanc K., Mueller I., Slaper-Cortenbach I., Marini F., Krause D., Deans R., Keating A., Prockop D., Horwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006, 8:315-317.
-
(2006)
Cytotherapy
, vol.8
, pp. 315-317
-
-
Dominici, M.1
Le Blanc, K.2
Mueller, I.3
Slaper-Cortenbach, I.4
Marini, F.5
Krause, D.6
Deans, R.7
Keating, A.8
Prockop, D.9
Horwitz, E.10
-
4
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., Swiergiel J.J., Marshall V.S., Jones J.M. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
5
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
6
-
-
77958569435
-
Induced pluripotency: history, mechanisms, and applications
-
Stadtfeld M., Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev. 2010, 24:2239-2263.
-
(2010)
Genes Dev.
, vol.24
, pp. 2239-2263
-
-
Stadtfeld, M.1
Hochedlinger, K.2
-
7
-
-
84881256653
-
Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds
-
Hou P., Li Y., Zhang X., Liu C., Guan J., Li H., Zhao T., Ye J., Yang W., Liu K., Ge J., Xu J., Zhang Q., Zhao Y., Deng H. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science 2013, 341:651-654.
-
(2013)
Science
, vol.341
, pp. 651-654
-
-
Hou, P.1
Li, Y.2
Zhang, X.3
Liu, C.4
Guan, J.5
Li, H.6
Zhao, T.7
Ye, J.8
Yang, W.9
Liu, K.10
Ge, J.11
Xu, J.12
Zhang, Q.13
Zhao, Y.14
Deng, H.15
-
8
-
-
84875953755
-
Stem cell metabolism in tissue development and aging
-
Shyh-Chang N., Daley G.Q., Cantley L.C. Stem cell metabolism in tissue development and aging. Development 2013, 140:2535-2547.
-
(2013)
Development
, vol.140
, pp. 2535-2547
-
-
Shyh-Chang, N.1
Daley, G.Q.2
Cantley, L.C.3
-
9
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden M.G., Cantley L.C., Thompson C.B. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009, 324:1029-1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
10
-
-
80051718140
-
Glucose reduction prevents replicative senescence and increases mitochondrial respiration in human mesenchymal stem cells
-
Lo T., Ho J.H., Yang M.H., Lee O.K. Glucose reduction prevents replicative senescence and increases mitochondrial respiration in human mesenchymal stem cells. Cell Transplant. 2011, 20:813-825.
-
(2011)
Cell Transplant.
, vol.20
, pp. 813-825
-
-
Lo, T.1
Ho, J.H.2
Yang, M.H.3
Lee, O.K.4
-
11
-
-
78049366735
-
Investigations into the metabolism of two-dimensional colony and suspended microcarrier cultures of human embryonic stem cells in serum-free media
-
Chen X., Chen A., Woo T.L., Choo A.B., Reuveny S., Oh S.K. Investigations into the metabolism of two-dimensional colony and suspended microcarrier cultures of human embryonic stem cells in serum-free media. Stem Cells Dev. 2010, 19:1781-1792.
-
(2010)
Stem Cells Dev.
, vol.19
, pp. 1781-1792
-
-
Chen, X.1
Chen, A.2
Woo, T.L.3
Choo, A.B.4
Reuveny, S.5
Oh, S.K.6
-
12
-
-
71349088314
-
Influence of lactic acid on the proliferation, metabolism, and differentiation of rabbit mesenchymal stem cells
-
Chen T., Zhou Y., Tan W.S. Influence of lactic acid on the proliferation, metabolism, and differentiation of rabbit mesenchymal stem cells. Cell Biol. Toxicol. 2009, 25:573-586.
-
(2009)
Cell Biol. Toxicol.
, vol.25
, pp. 573-586
-
-
Chen, T.1
Zhou, Y.2
Tan, W.S.3
-
13
-
-
84868351585
-
Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal
-
Zhang J., Nuebel E., Daley G.Q., Koehler C.M., Teitell M.A. Metabolic regulation in pluripotent stem cells during reprogramming and self-renewal. Cell Stem Cell 2012, 11:589-595.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 589-595
-
-
Zhang, J.1
Nuebel, E.2
Daley, G.Q.3
Koehler, C.M.4
Teitell, M.A.5
-
14
-
-
77649187905
-
The Warburg effect and mitochondrial stability in cancer cells
-
Gogvadze V., Zhivotovsky B., Orrenius S. The Warburg effect and mitochondrial stability in cancer cells. Mol. Aspects Med. 2010, 31:60-74.
-
(2010)
Mol. Aspects Med.
, vol.31
, pp. 60-74
-
-
Gogvadze, V.1
Zhivotovsky, B.2
Orrenius, S.3
-
15
-
-
84877050463
-
Glucose plays a main role in human fibroblasts adaptation to hypoxia
-
Baracca A., Sgarbi G., Padula A., Solaini G. Glucose plays a main role in human fibroblasts adaptation to hypoxia. Int. J. Biochem. Cell Biol. 2013, 45:1356-1365.
-
(2013)
Int. J. Biochem. Cell Biol.
, vol.45
, pp. 1356-1365
-
-
Baracca, A.1
Sgarbi, G.2
Padula, A.3
Solaini, G.4
-
16
-
-
84872160110
-
Influence of threonine metabolism on S-adenosylmethionine and histone methylation
-
Shyh-Chang N., Locasale J.W., Lyssiotis C.A., Zheng Y., Teo R.Y., Ratanasirintrawoot S., Zhang J., Onder T., Unternaehrer J.J., Zhu H., Asara J.M., Daley G.Q., Cantley L.C. Influence of threonine metabolism on S-adenosylmethionine and histone methylation. Science 2013, 339:222-226.
-
(2013)
Science
, vol.339
, pp. 222-226
-
-
Shyh-Chang, N.1
Locasale, J.W.2
Lyssiotis, C.A.3
Zheng, Y.4
Teo, R.Y.5
Ratanasirintrawoot, S.6
Zhang, J.7
Onder, T.8
Unternaehrer, J.J.9
Zhu, H.10
Asara, J.M.11
Daley, G.Q.12
Cantley, L.C.13
-
17
-
-
84868347607
-
Metabolic plasticity in stem cell homeostasis and differentiation
-
Folmes C.D., Dzeja P.P., Nelson T.J., Terzic A. Metabolic plasticity in stem cell homeostasis and differentiation. Cell Stem Cell 2012, 11:596-606.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 596-606
-
-
Folmes, C.D.1
Dzeja, P.P.2
Nelson, T.J.3
Terzic, A.4
-
18
-
-
84888069210
-
Allogeneic cell therapy bioprocess economics and optimization: single-use cell expansion technologies
-
Simaria A.S., Hassan S., Varadaraju H., Rowley J., Warren K., Vanek P., Farid S.S. Allogeneic cell therapy bioprocess economics and optimization: single-use cell expansion technologies. Biotechnol. Bioeng. 2014, 111:69-83.
-
(2014)
Biotechnol. Bioeng.
, vol.111
, pp. 69-83
-
-
Simaria, A.S.1
Hassan, S.2
Varadaraju, H.3
Rowley, J.4
Warren, K.5
Vanek, P.6
Farid, S.S.7
-
19
-
-
80053449223
-
Stem cell cultivation in bioreactors
-
Rodrigues C.A., Fernandes T.G., Diogo M.M., da Silva C.L., Cabral J.M. Stem cell cultivation in bioreactors. Biotechnol. Adv. 2011, 29:815-829.
-
(2011)
Biotechnol. Adv.
, vol.29
, pp. 815-829
-
-
Rodrigues, C.A.1
Fernandes, T.G.2
Diogo, M.M.3
da Silva, C.L.4
Cabral, J.M.5
-
20
-
-
34547509586
-
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
-
Funes J.M., Quintero M., Henderson S., Martinez D., Qureshi U., Westwood C., Clements M.O., Bourboulia D., Pedley R.B., Moncada S., Boshoff C. Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. PNAS 2007, 104:6223-6228.
-
(2007)
PNAS
, vol.104
, pp. 6223-6228
-
-
Funes, J.M.1
Quintero, M.2
Henderson, S.3
Martinez, D.4
Qureshi, U.5
Westwood, C.6
Clements, M.O.7
Bourboulia, D.8
Pedley, R.B.9
Moncada, S.10
Boshoff, C.11
-
21
-
-
47949101704
-
Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment
-
Mylotte L.A., Duffy A.M., Murphy M., O'Brien T., Samali A., Barry F., Szegezdi E. Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment. Stem Cells 2008, 26:1325-1336.
-
(2008)
Stem Cells
, vol.26
, pp. 1325-1336
-
-
Mylotte, L.A.1
Duffy, A.M.2
Murphy, M.3
O'Brien, T.4
Samali, A.5
Barry, F.6
Szegezdi, E.7
-
22
-
-
79960666063
-
The metabolism of human mesenchymal stem cells during proliferation and differentiation
-
Pattappa G., Heywood H.K., de Bruijn J.D., Lee D.A. The metabolism of human mesenchymal stem cells during proliferation and differentiation. J. Cell. Physiol. 2011, 226:2562-2570.
-
(2011)
J. Cell. Physiol.
, vol.226
, pp. 2562-2570
-
-
Pattappa, G.1
Heywood, H.K.2
de Bruijn, J.D.3
Lee, D.A.4
-
23
-
-
84872798232
-
Autocrine fibroblast growth factor 2-mediated interactions between human mesenchymal stem cells and the extracellular matrix under varying oxygen tension
-
Kim J., Ma T. Autocrine fibroblast growth factor 2-mediated interactions between human mesenchymal stem cells and the extracellular matrix under varying oxygen tension. J. Cell. Biochem. 2013, 114:716-727.
-
(2013)
J. Cell. Biochem.
, vol.114
, pp. 716-727
-
-
Kim, J.1
Ma, T.2
-
24
-
-
24144444133
-
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
-
Brunelle J.K., Bell E.L., Quesada N.M., Vercauteren K., Tiranti V., Zeviani M., Scarpulla R.C., Chandel N.S. Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metab. 2005, 1:409-414.
-
(2005)
Cell Metab.
, vol.1
, pp. 409-414
-
-
Brunelle, J.K.1
Bell, E.L.2
Quesada, N.M.3
Vercauteren, K.4
Tiranti, V.5
Zeviani, M.6
Scarpulla, R.C.7
Chandel, N.S.8
-
25
-
-
70350337933
-
Metabolic phenotyping of a model of adipocyte differentiation
-
Roberts L.D., Virtue S., Vidal-Puig A., Nicholls A.W., Griffin J.L. Metabolic phenotyping of a model of adipocyte differentiation. Physiol. Genomics 2009, 39:109-119.
-
(2009)
Physiol. Genomics
, vol.39
, pp. 109-119
-
-
Roberts, L.D.1
Virtue, S.2
Vidal-Puig, A.3
Nicholls, A.W.4
Griffin, J.L.5
-
26
-
-
14844337550
-
Oxygen consumption in undifferentiated versus differentiated adipogenic mesenchymal precursor cells
-
von Heimburg D., Hemmrich K., Zachariah S., Staiger H., Pallua N. Oxygen consumption in undifferentiated versus differentiated adipogenic mesenchymal precursor cells. Respir. Physiol. Neurobiol. 2005, 146:107-116.
-
(2005)
Respir. Physiol. Neurobiol.
, vol.146
, pp. 107-116
-
-
von Heimburg, D.1
Hemmrich, K.2
Zachariah, S.3
Staiger, H.4
Pallua, N.5
-
27
-
-
80053904684
-
Mitochondrial complex III ROS regulate adipocyte differentiation
-
Tormos K.V., Anso E., Hamanaka R.B., Eisenbart J., Joseph J., Kalyanaraman B., Chandel N.S. Mitochondrial complex III ROS regulate adipocyte differentiation. Cell Metab. 2011, 14:537-544.
-
(2011)
Cell Metab.
, vol.14
, pp. 537-544
-
-
Tormos, K.V.1
Anso, E.2
Hamanaka, R.B.3
Eisenbart, J.4
Joseph, J.5
Kalyanaraman, B.6
Chandel, N.S.7
-
28
-
-
79961011901
-
Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells
-
Kanda Y., Hinata T., Kang S.W., Watanabe Y. Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells. Life Sci. 2011, 89:250-258.
-
(2011)
Life Sci.
, vol.89
, pp. 250-258
-
-
Kanda, Y.1
Hinata, T.2
Kang, S.W.3
Watanabe, Y.4
-
29
-
-
84863901102
-
Changes in expression of the antioxidant enzyme SOD3 occur upon differentiation of human bone marrow-derived mesenchymal stem cells in vitro
-
Nightingale H., Kemp K., Gray E., Hares K., Mallam E., Scolding N., Wilkins A. Changes in expression of the antioxidant enzyme SOD3 occur upon differentiation of human bone marrow-derived mesenchymal stem cells in vitro. Stem Cells Dev. 2012, 21:2026-2035.
-
(2012)
Stem Cells Dev.
, vol.21
, pp. 2026-2035
-
-
Nightingale, H.1
Kemp, K.2
Gray, E.3
Hares, K.4
Mallam, E.5
Scolding, N.6
Wilkins, A.7
-
30
-
-
36249020427
-
Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan
-
Fehrer C., Brunauer R., Laschober G., Unterluggauer H., Reitinger S., Kloss F., Gully C., Gassner R., Lepperdinger G. Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan. Aging Cell 2007, 6:745-757.
-
(2007)
Aging Cell
, vol.6
, pp. 745-757
-
-
Fehrer, C.1
Brunauer, R.2
Laschober, G.3
Unterluggauer, H.4
Reitinger, S.5
Kloss, F.6
Gully, C.7
Gassner, R.8
Lepperdinger, G.9
-
31
-
-
20744449945
-
Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling
-
Zhou S., Lechpammer S., Greenberger J.S., Glowacki J. Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling. J. Biol. Chem. 2005, 280:22688-22696.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 22688-22696
-
-
Zhou, S.1
Lechpammer, S.2
Greenberger, J.S.3
Glowacki, J.4
-
32
-
-
34548103553
-
Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor gamma signaling
-
Chuang C.C., Yang R.S., Tsai K.S., Ho F.M., Liu S.H. Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt, and peroxisome proliferator-activated receptor gamma signaling. Endocrinology 2007, 148:4267-4275.
-
(2007)
Endocrinology
, vol.148
, pp. 4267-4275
-
-
Chuang, C.C.1
Yang, R.S.2
Tsai, K.S.3
Ho, F.M.4
Liu, S.H.5
-
33
-
-
49249086654
-
Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells
-
Chen C.T., Shih Y.R., Kuo T.K., Lee O.K., Wei Y.H. Coordinated changes of mitochondrial biogenesis and antioxidant enzymes during osteogenic differentiation of human mesenchymal stem cells. Stem Cells 2008, 26:960-968.
-
(2008)
Stem Cells
, vol.26
, pp. 960-968
-
-
Chen, C.T.1
Shih, Y.R.2
Kuo, T.K.3
Lee, O.K.4
Wei, Y.H.5
-
34
-
-
34548795843
-
Effects of high glucose on mesenchymal stem cell proliferation and differentiation
-
Li Y.M., Schilling T., Benisch P., Zeck S., Meissner-Weigl J., Schneider D., Limbert C., Seufert J., Kassem M., Schutze N., Jakob F., Ebert R. Effects of high glucose on mesenchymal stem cell proliferation and differentiation. Biochem. Biophys. Res. Commun. 2007, 363:209-215.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.363
, pp. 209-215
-
-
Li, Y.M.1
Schilling, T.2
Benisch, P.3
Zeck, S.4
Meissner-Weigl, J.5
Schneider, D.6
Limbert, C.7
Seufert, J.8
Kassem, M.9
Schutze, N.10
Jakob, F.11
Ebert, R.12
-
35
-
-
33645125788
-
Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells
-
Malladi P., Xu Y., Chiou M., Giaccia A.J., Longaker M.T. Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells. Am. J. Physiol. Cell Physiol. 2006, 290:C1139-C1146.
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.290
-
-
Malladi, P.1
Xu, Y.2
Chiou, M.3
Giaccia, A.J.4
Longaker, M.T.5
-
36
-
-
20144385673
-
Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells
-
Wang D.W., Fermor B., Gimble J.M., Awad H.A., Guilak F. Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells. J. Cell. Physiol. 2005, 204:184-191.
-
(2005)
J. Cell. Physiol.
, vol.204
, pp. 184-191
-
-
Wang, D.W.1
Fermor, B.2
Gimble, J.M.3
Awad, H.A.4
Guilak, F.5
-
37
-
-
48749086529
-
Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1alpha
-
Kanichai M., Ferguson D., Prendergast P.J., Campbell V.A. Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: a role for AKT and hypoxia-inducible factor (HIF)-1alpha. J. Cell. Physiol. 2008, 216:708-715.
-
(2008)
J. Cell. Physiol.
, vol.216
, pp. 708-715
-
-
Kanichai, M.1
Ferguson, D.2
Prendergast, P.J.3
Campbell, V.A.4
-
38
-
-
23844493183
-
Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9
-
Robins J.C., Akeno N., Mukherjee A., Dalal R.R., Aronow B.J., Koopman P., Clemens T.L. Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9. Bone 2005, 37:313-322.
-
(2005)
Bone
, vol.37
, pp. 313-322
-
-
Robins, J.C.1
Akeno, N.2
Mukherjee, A.3
Dalal, R.R.4
Aronow, B.J.5
Koopman, P.6
Clemens, T.L.7
-
39
-
-
79959221064
-
Energy metabolism in human pluripotent stem cells and their differentiated counterparts
-
Varum S., Rodrigues A.S., Moura M.B., Momcilovic O., Easley C.A.t, Ramalho-Santos J., Van Houten B., Schatten G. Energy metabolism in human pluripotent stem cells and their differentiated counterparts. PLoS One 2011, 6:e20914.
-
(2011)
PLoS One
, vol.6
-
-
Varum, S.1
Rodrigues, A.S.2
Moura, M.B.3
Momcilovic, O.4
Easley, C.5
Ramalho-Santos, J.6
Van Houten, B.7
Schatten, G.8
-
40
-
-
84863111875
-
Human embryonic stem cells and embryonal carcinoma cells have overlapping and distinct metabolic signatures
-
Abu Dawud R., Schreiber K., Schomburg D., Adjaye J. Human embryonic stem cells and embryonal carcinoma cells have overlapping and distinct metabolic signatures. PLoS One 2012, 7:e39896.
-
(2012)
PLoS One
, vol.7
-
-
Abu Dawud, R.1
Schreiber, K.2
Schomburg, D.3
Adjaye, J.4
-
41
-
-
33846420629
-
A high glycolytic flux supports the proliferative potential of murine embryonic stem cells
-
Kondoh H., Lleonart M.E., Nakashima Y., Yokode M., Tanaka M., Bernard D., Gil J., Beach D. A high glycolytic flux supports the proliferative potential of murine embryonic stem cells. Antioxid. Redox Signaling 2007, 9:293-299.
-
(2007)
Antioxid. Redox Signaling
, vol.9
, pp. 293-299
-
-
Kondoh, H.1
Lleonart, M.E.2
Nakashima, Y.3
Yokode, M.4
Tanaka, M.5
Bernard, D.6
Gil, J.7
Beach, D.8
-
42
-
-
84860531487
-
HIF1alpha induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition
-
Zhou W., Choi M., Margineantu D., Margaretha L., Hesson J., Cavanaugh C., Blau C.A., Horwitz M.S., Hockenbery D., Ware C., Ruohola-Baker H. HIF1alpha induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. EMBO J. 2012, 31:2103-2116.
-
(2012)
EMBO J.
, vol.31
, pp. 2103-2116
-
-
Zhou, W.1
Choi, M.2
Margineantu, D.3
Margaretha, L.4
Hesson, J.5
Cavanaugh, C.6
Blau, C.A.7
Horwitz, M.S.8
Hockenbery, D.9
Ware, C.10
Ruohola-Baker, H.11
-
43
-
-
79953000879
-
Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells
-
Mandal S., Lindgren A.G., Srivastava A.S., Clark A.T., Banerjee U. Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells. Stem Cells 2011, 29:486-495.
-
(2011)
Stem Cells
, vol.29
, pp. 486-495
-
-
Mandal, S.1
Lindgren, A.G.2
Srivastava, A.S.3
Clark, A.T.4
Banerjee, U.5
-
44
-
-
77953286613
-
Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia
-
Fernandes T.G., Diogo M.M., Fernandes-Platzgummer A., da Silva C.L., Cabral J.M. Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia. Stem Cell Res. 2010, 5:76-89.
-
(2010)
Stem Cell Res.
, vol.5
, pp. 76-89
-
-
Fernandes, T.G.1
Diogo, M.M.2
Fernandes-Platzgummer, A.3
da Silva, C.L.4
Cabral, J.M.5
-
45
-
-
70349860263
-
Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain
-
Varum S., Momcilovic O., Castro C., Ben-Yehudah A., Ramalho-Santos J., Navara C.S. Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain. Stem Cell Res. 2009, 3:142-156.
-
(2009)
Stem Cell Res.
, vol.3
, pp. 142-156
-
-
Varum, S.1
Momcilovic, O.2
Castro, C.3
Ben-Yehudah, A.4
Ramalho-Santos, J.5
Navara, C.S.6
-
46
-
-
78650704049
-
Effect of long-term culture of mouse embryonic stem cells under low oxygen concentration as well as on glycosaminoglycan hyaluronan on cell proliferation and differentiation
-
Ramirez M.A., Pericuesta E., Yanez-Mo M., Palasz A., Gutierrez-Adan A. Effect of long-term culture of mouse embryonic stem cells under low oxygen concentration as well as on glycosaminoglycan hyaluronan on cell proliferation and differentiation. Cell Proliferat. 2011, 44:75-85.
-
(2011)
Cell Proliferat.
, vol.44
, pp. 75-85
-
-
Ramirez, M.A.1
Pericuesta, E.2
Yanez-Mo, M.3
Palasz, A.4
Gutierrez-Adan, A.5
-
47
-
-
58149154747
-
Identification of oxygen-sensitive transcriptional programs in human embryonic stem cells
-
Westfall S.D., Sachdev S., Das P., Hearne L.B., Hannink M., Roberts R.M., Ezashi T. Identification of oxygen-sensitive transcriptional programs in human embryonic stem cells. Stem Cells Dev. 2008, 17:869-881.
-
(2008)
Stem Cells Dev.
, vol.17
, pp. 869-881
-
-
Westfall, S.D.1
Sachdev, S.2
Das, P.3
Hearne, L.B.4
Hannink, M.5
Roberts, R.M.6
Ezashi, T.7
-
48
-
-
77954822251
-
Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose
-
Crespo F.L., Sobrado V.R., Gomez L., Cervera A.M., McCreath K.J. Mitochondrial reactive oxygen species mediate cardiomyocyte formation from embryonic stem cells in high glucose. Stem Cells 2010, 28:1132-1142.
-
(2010)
Stem Cells
, vol.28
, pp. 1132-1142
-
-
Crespo, F.L.1
Sobrado, V.R.2
Gomez, L.3
Cervera, A.M.4
McCreath, K.J.5
-
49
-
-
33748266897
-
High glucose increase cell cycle regulatory proteins level of mouse embryonic stem cells via PI3-K/Akt and MAPKs signal pathways
-
Kim Y.H., Heo J.S., Han H.J. High glucose increase cell cycle regulatory proteins level of mouse embryonic stem cells via PI3-K/Akt and MAPKs signal pathways. J. Cell. Physiol. 2006, 209:94-102.
-
(2006)
J. Cell. Physiol.
, vol.209
, pp. 94-102
-
-
Kim, Y.H.1
Heo, J.S.2
Han, H.J.3
-
50
-
-
83455235489
-
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
-
Zhang J., Khvorostov I., Hong J.S., Oktay Y., Vergnes L., Nuebel E., Wahjudi P.N., Setoguchi K., Wang G., Do A., Jung H.J., McCaffery J.M., Kurland I.J., Reue K., Lee W.N., Koehler C.M., Teitell M.A. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 2011, 30:4860-4873.
-
(2011)
EMBO J.
, vol.30
, pp. 4860-4873
-
-
Zhang, J.1
Khvorostov, I.2
Hong, J.S.3
Oktay, Y.4
Vergnes, L.5
Nuebel, E.6
Wahjudi, P.N.7
Setoguchi, K.8
Wang, G.9
Do, A.10
Jung, H.J.11
McCaffery, J.M.12
Kurland, I.J.13
Reue, K.14
Lee, W.N.15
Koehler, C.M.16
Teitell, M.A.17
-
51
-
-
78650636514
-
Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells
-
Xu C., Police S., Hassanipour M., Li Y., Chen Y., Priest C., O'Sullivan C., Laflamme M.A., Zhu W.Z., Van Biber B., Hegerova L., Yang J., Delavan-Boorsma K., Davies A., Lebkowski J., Gold J.D. Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells. Regener. Med. 2011, 6:53-66.
-
(2011)
Regener. Med.
, vol.6
, pp. 53-66
-
-
Xu, C.1
Police, S.2
Hassanipour, M.3
Li, Y.4
Chen, Y.5
Priest, C.6
O'Sullivan, C.7
Laflamme, M.A.8
Zhu, W.Z.9
Van Biber, B.10
Hegerova, L.11
Yang, J.12
Delavan-Boorsma, K.13
Davies, A.14
Lebkowski, J.15
Gold, J.D.16
-
52
-
-
79952201666
-
Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns
-
Sepulveda D.E., Andrews B.A., Papoutsakis E.T., Asenjo J.A. Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns. Biotechnol. Prog. 2010, 26:1222-1229.
-
(2010)
Biotechnol. Prog.
, vol.26
, pp. 1222-1229
-
-
Sepulveda, D.E.1
Andrews, B.A.2
Papoutsakis, E.T.3
Asenjo, J.A.4
-
53
-
-
84872048038
-
Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
-
Tohyama S., Hattori F., Sano M., Hishiki T., Nagahata Y., Matsuura T., Hashimoto H., Suzuki T., Yamashita H., Satoh Y., Egashira T., Seki T., Muraoka N., Yamakawa H., Ohgino Y., Tanaka T., Yoichi M., Yuasa S., Murata M., Suematsu M., Fukuda K. Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell 2013, 12:127-137.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 127-137
-
-
Tohyama, S.1
Hattori, F.2
Sano, M.3
Hishiki, T.4
Nagahata, Y.5
Matsuura, T.6
Hashimoto, H.7
Suzuki, T.8
Yamashita, H.9
Satoh, Y.10
Egashira, T.11
Seki, T.12
Muraoka, N.13
Yamakawa, H.14
Ohgino, Y.15
Tanaka, T.16
Yoichi, M.17
Yuasa, S.18
Murata, M.19
Suematsu, M.20
Fukuda, K.21
more..
-
54
-
-
33846501510
-
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells
-
Chung S., Dzeja P.P., Faustino R.S., Perez-Terzic C., Behfar A., Terzic A. Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells. Nat. Clin. Pract. Cardiovasc. Med. 2007, 4(Suppl 1):S60-S67.
-
(2007)
Nat. Clin. Pract. Cardiovasc. Med.
, vol.4
, Issue.SUPPL 1
-
-
Chung, S.1
Dzeja, P.P.2
Faustino, R.S.3
Perez-Terzic, C.4
Behfar, A.5
Terzic, A.6
-
55
-
-
78650983173
-
Effect of glucose concentration during embryoid body (EB) formation from mouse embryonic stem cells on EB growth and cell differentiation
-
Mochizuki H., Ohnuki Y., Kurosawa H. Effect of glucose concentration during embryoid body (EB) formation from mouse embryonic stem cells on EB growth and cell differentiation. J. Biosci. Bioeng. 2011, 111:92-97.
-
(2011)
J. Biosci. Bioeng.
, vol.111
, pp. 92-97
-
-
Mochizuki, H.1
Ohnuki, Y.2
Kurosawa, H.3
-
56
-
-
77950523031
-
Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage
-
Ji A.R., Ku S.Y., Cho M.S., Kim Y.Y., Kim Y.J., Oh S.K., Kim S.H., Moon S.Y., Choi Y.M. Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage. Exp. Mol. Med. 2010, 42:175-186.
-
(2010)
Exp. Mol. Med.
, vol.42
, pp. 175-186
-
-
Ji, A.R.1
Ku, S.Y.2
Cho, M.S.3
Kim, Y.Y.4
Kim, Y.J.5
Oh, S.K.6
Kim, S.H.7
Moon, S.Y.8
Choi, Y.M.9
-
57
-
-
33751411413
-
Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures
-
Tsatmali M., Walcott E.C., Makarenkova H., Crossin K.L. Reactive oxygen species modulate the differentiation of neurons in clonal cortical cultures. Mol. Cell Neurosci. 2006, 33:345-357.
-
(2006)
Mol. Cell Neurosci.
, vol.33
, pp. 345-357
-
-
Tsatmali, M.1
Walcott, E.C.2
Makarenkova, H.3
Crossin, K.L.4
-
58
-
-
57149130272
-
Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production
-
Konopka R., Kubala L., Lojek A., Pachernik J. Alternation of retinoic acid induced neural differentiation of P19 embryonal carcinoma cells by reduction of reactive oxygen species intracellular production. Neuro. Endocrinol. Lett. 2008, 29:770-774.
-
(2008)
Neuro. Endocrinol. Lett.
, vol.29
, pp. 770-774
-
-
Konopka, R.1
Kubala, L.2
Lojek, A.3
Pachernik, J.4
-
59
-
-
79952120270
-
Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation
-
Dienelt A., zur Nieden N.I. Hyperglycemia impairs skeletogenesis from embryonic stem cells by affecting osteoblast and osteoclast differentiation. Stem Cells Dev. 2011, 20:465-474.
-
(2011)
Stem Cells Dev.
, vol.20
, pp. 465-474
-
-
Dienelt, A.1
zur Nieden, N.I.2
-
60
-
-
82955235220
-
The full spectrum of physiological oxygen tensions and step-changes in oxygen tension affects the neural differentiation of mouse embryonic stem cells
-
Mondragon-Teran P., Baboo J.Z., Mason C., Lye G.J., Veraitch F.S. The full spectrum of physiological oxygen tensions and step-changes in oxygen tension affects the neural differentiation of mouse embryonic stem cells. Biotechnol. Prog. 2011, 27:1700-1708.
-
(2011)
Biotechnol. Prog.
, vol.27
, pp. 1700-1708
-
-
Mondragon-Teran, P.1
Baboo, J.Z.2
Mason, C.3
Lye, G.J.4
Veraitch, F.S.5
-
61
-
-
79551521189
-
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells
-
Birket M.J., Orr A.L., Gerencser A.A., Madden D.T., Vitelli C., Swistowski A., Brand M.D., Zeng X. A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells. J. Cell Sci. 2011, 124:348-358.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 348-358
-
-
Birket, M.J.1
Orr, A.L.2
Gerencser, A.A.3
Madden, D.T.4
Vitelli, C.5
Swistowski, A.6
Brand, M.D.7
Zeng, X.8
-
62
-
-
80054730400
-
Neuronal differentiation involves a shift from glucose oxidation to fermentation
-
Fornazari M., Nascimento I.C., Nery A.A., da Silva C.C., Kowaltowski A.J., Ulrich H. Neuronal differentiation involves a shift from glucose oxidation to fermentation. J. Bioenergy Biomembr. 2011, 43:531-539.
-
(2011)
J. Bioenergy Biomembr.
, vol.43
, pp. 531-539
-
-
Fornazari, M.1
Nascimento, I.C.2
Nery, A.A.3
da Silva, C.C.4
Kowaltowski, A.J.5
Ulrich, H.6
-
63
-
-
84855490988
-
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
-
Panopoulos A.D., Yanes O., Ruiz S., Kida Y.S., Diep D., Tautenhahn R., Herrerias A., Batchelder E.M., Plongthongkum N., Lutz M., Berggren W.T., Zhang K., Evans R.M., Siuzdak G., Izpisua Belmonte J.C. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Res. 2012, 22:168-177.
-
(2012)
Cell Res.
, vol.22
, pp. 168-177
-
-
Panopoulos, A.D.1
Yanes, O.2
Ruiz, S.3
Kida, Y.S.4
Diep, D.5
Tautenhahn, R.6
Herrerias, A.7
Batchelder, E.M.8
Plongthongkum, N.9
Lutz, M.10
Berggren, W.T.11
Zhang, K.12
Evans, R.M.13
Siuzdak, G.14
Izpisua Belmonte, J.C.15
-
64
-
-
78649647814
-
Reprogramming of human primary somatic cells by OCT4 and chemical compounds
-
Zhu S., Li W., Zhou H., Wei W., Ambasudhan R., Lin T., Kim J., Zhang K., Ding S. Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell 2010, 7:651-655.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 651-655
-
-
Zhu, S.1
Li, W.2
Zhou, H.3
Wei, W.4
Ambasudhan, R.5
Lin, T.6
Kim, J.7
Zhang, K.8
Ding, S.9
-
65
-
-
69249210977
-
Hypoxia enhances the generation of induced pluripotent stem cells
-
Yoshida Y., Takahashi K., Okita K., Ichisaka T., Yamanaka S. Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 2009, 5:237-241.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 237-241
-
-
Yoshida, Y.1
Takahashi, K.2
Okita, K.3
Ichisaka, T.4
Yamanaka, S.5
-
66
-
-
84860355832
-
Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures
-
Fluri D.A., Tonge P.D., Song H., Baptista R.P., Shakiba N., Shukla S., Clarke G., Nagy A., Zandstra P.W. Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures. Nat. Methods 2012, 9:509-516.
-
(2012)
Nat. Methods
, vol.9
, pp. 509-516
-
-
Fluri, D.A.1
Tonge, P.D.2
Song, H.3
Baptista, R.P.4
Shakiba, N.5
Shukla, S.6
Clarke, G.7
Nagy, A.8
Zandstra, P.W.9
-
67
-
-
84857814973
-
Patterns of amino acid metabolism by proliferating human mesenchymal stem cells
-
Higuera G.A., Schop D., Spitters T.W., van Dijkhuizen-Radersma R., Bracke M., de Bruijn J.D., Martens D., Karperien M., van Boxtel A., van Blitterswijk C.A. Patterns of amino acid metabolism by proliferating human mesenchymal stem cells. Tissue Eng. Part A 2012, 18:654-664.
-
(2012)
Tissue Eng. Part A
, vol.18
, pp. 654-664
-
-
Higuera, G.A.1
Schop, D.2
Spitters, T.W.3
van Dijkhuizen-Radersma, R.4
Bracke, M.5
de Bruijn, J.D.6
Martens, D.7
Karperien, M.8
van Boxtel, A.9
van Blitterswijk, C.A.10
-
68
-
-
78650051864
-
Hypoxia and amino acid supplementation synergistically promote the osteogenesis of human mesenchymal stem cells on silk protein scaffolds
-
Sengupta S., Park S.H., Patel A., Carn J., Lee K., Kaplan D.L. Hypoxia and amino acid supplementation synergistically promote the osteogenesis of human mesenchymal stem cells on silk protein scaffolds. Tissue Eng. Part A 2010, 16:3623-3634.
-
(2010)
Tissue Eng. Part A
, vol.16
, pp. 3623-3634
-
-
Sengupta, S.1
Park, S.H.2
Patel, A.3
Carn, J.4
Lee, K.5
Kaplan, D.L.6
-
69
-
-
66849131401
-
Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling
-
Kim M.S., Wu K.Y., Auyeung V., Chen Q., Gruppuso P.A., Phornphutkul C. Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling. Am. J. Physiol. Endocrinol. Metab. 2009, 296:E1374-E1382.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.296
-
-
Kim, M.S.1
Wu, K.Y.2
Auyeung, V.3
Chen, Q.4
Gruppuso, P.A.5
Phornphutkul, C.6
-
70
-
-
7044234995
-
Regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis
-
Kim J.E., Chen J. regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis. Diabetes 2004, 53:2748-2756.
-
(2004)
Diabetes
, vol.53
, pp. 2748-2756
-
-
Kim, J.E.1
Chen, J.2
-
71
-
-
70350504095
-
Quantifying in vitro growth and metabolism kinetics of human mesenchymal stem cells using a mathematical model
-
Higuera G., Schop D., Janssen F., van Dijkhuizen-Radersma R., van Boxtel T., van Blitterswijk C.A. Quantifying in vitro growth and metabolism kinetics of human mesenchymal stem cells using a mathematical model. Tissue Eng. Part A 2009, 15:2653-2663.
-
(2009)
Tissue Eng. Part A
, vol.15
, pp. 2653-2663
-
-
Higuera, G.1
Schop, D.2
Janssen, F.3
van Dijkhuizen-Radersma, R.4
van Boxtel, T.5
van Blitterswijk, C.A.6
-
72
-
-
68749109438
-
Growth, metabolism, and growth inhibitors of mesenchymal stem cells
-
Schop D., Janssen F.W., van Rijn L.D., Fernandes H., Bloem R.M., de Bruijn J.D., van Dijkhuizen-Radersma R. Growth, metabolism, and growth inhibitors of mesenchymal stem cells. Tissue Eng. Part A 2009, 15:1877-1886.
-
(2009)
Tissue Eng. Part A
, vol.15
, pp. 1877-1886
-
-
Schop, D.1
Janssen, F.W.2
van Rijn, L.D.3
Fernandes, H.4
Bloem, R.M.5
de Bruijn, J.D.6
van Dijkhuizen-Radersma, R.7
-
73
-
-
49149128088
-
Wnt and steroid pathways control glutamate signalling by regulating glutamine synthetase activity in osteoblastic cells
-
Olkku A., Mahonen A. Wnt and steroid pathways control glutamate signalling by regulating glutamine synthetase activity in osteoblastic cells. Bone 2008, 43:483-493.
-
(2008)
Bone
, vol.43
, pp. 483-493
-
-
Olkku, A.1
Mahonen, A.2
-
74
-
-
51049091904
-
Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line
-
Yoo H., Antoniewicz M.R., Stephanopoulos G., Kelleher J.K. Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line. J. Biol. Chem. 2008, 283:20621-20627.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 20621-20627
-
-
Yoo, H.1
Antoniewicz, M.R.2
Stephanopoulos, G.3
Kelleher, J.K.4
-
75
-
-
33646771362
-
Glutamine protects articular chondrocytes from heat stress and NO-induced apoptosis with HSP70 expression
-
Tonomura H., Takahashi K.A., Mazda O., Arai Y., Inoue A., Terauchi R., Shin-Ya M., Kishida T., Imanishi J., Kubo T. Glutamine protects articular chondrocytes from heat stress and NO-induced apoptosis with HSP70 expression. Osteoarthr. Cartilage 2006, 14:545-553.
-
(2006)
Osteoarthr. Cartilage
, vol.14
, pp. 545-553
-
-
Tonomura, H.1
Takahashi, K.A.2
Mazda, O.3
Arai, Y.4
Inoue, A.5
Terauchi, R.6
Shin-Ya, M.7
Kishida, T.8
Imanishi, J.9
Kubo, T.10
-
76
-
-
72249097517
-
Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions
-
Fernandes T.G., Fernandes-Platzgummer A.M., da Silva C.L., Diogo M.M., Cabral J.M. Kinetic and metabolic analysis of mouse embryonic stem cell expansion under serum-free conditions. Biotechnol. Lett. 2010, 32:171-179.
-
(2010)
Biotechnol. Lett.
, vol.32
, pp. 171-179
-
-
Fernandes, T.G.1
Fernandes-Platzgummer, A.M.2
da Silva, C.L.3
Diogo, M.M.4
Cabral, J.M.5
-
77
-
-
77951486317
-
L-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture
-
Washington J.M., Rathjen J., Felquer F., Lonic A., Bettess M.D., Hamra N., Semendric L., Tan B.S., Lake J.A., Keough R.A., Morris M.B., Rathjen P.D. l-Proline induces differentiation of ES cells: a novel role for an amino acid in the regulation of pluripotent cells in culture. Am. J. Physiol. Cell Physiol. 2010, 298:C982-C992.
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
-
-
Washington, J.M.1
Rathjen, J.2
Felquer, F.3
Lonic, A.4
Bettess, M.D.5
Hamra, N.6
Semendric, L.7
Tan, B.S.8
Lake, J.A.9
Keough, R.A.10
Morris, M.B.11
Rathjen, P.D.12
-
78
-
-
81055126626
-
Autophagy in human embryonic stem cells
-
Tra T., Gong L., Kao L.P., Li X.L., Grandela C., Devenish R.J., Wolvetang E., Prescott M. Autophagy in human embryonic stem cells. PLoS One 2011, 6:e27485.
-
(2011)
PLoS One
, vol.6
-
-
Tra, T.1
Gong, L.2
Kao, L.P.3
Li, X.L.4
Grandela, C.5
Devenish, R.J.6
Wolvetang, E.7
Prescott, M.8
-
79
-
-
66049149059
-
MTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells
-
Zhou J., Su P., Wang L., Chen J., Zimmermann M., Genbacev O., Afonja O., Horne M.C., Tanaka T., Duan E., Fisher S.J., Liao J., Wang F. mTOR supports long-term self-renewal and suppresses mesoderm and endoderm activities of human embryonic stem cells. PNAS 2009, 106:7840-7845.
-
(2009)
PNAS
, vol.106
, pp. 7840-7845
-
-
Zhou, J.1
Su, P.2
Wang, L.3
Chen, J.4
Zimmermann, M.5
Genbacev, O.6
Afonja, O.7
Horne, M.C.8
Tanaka, T.9
Duan, E.10
Fisher, S.J.11
Liao, J.12
Wang, F.13
-
80
-
-
84875253392
-
Stem cell metabolic and spectroscopic profiling
-
Ramm Sander P., Hau P., Koch S., Schutze K., Bogdahn U., Kalbitzer H.R., Aigner L. Stem cell metabolic and spectroscopic profiling. Trends Biotechnol. 2013, 31:204-213.
-
(2013)
Trends Biotechnol.
, vol.31
, pp. 204-213
-
-
Ramm Sander, P.1
Hau, P.2
Koch, S.3
Schutze, K.4
Bogdahn, U.5
Kalbitzer, H.R.6
Aigner, L.7
-
81
-
-
84892506464
-
Stem cell engineering in bioreactors for large scale bioprocessing
-
Liu N., Zang R., Yang S.T., Li Y. Stem cell engineering in bioreactors for large scale bioprocessing. Eng. Life Sci. 2014, 14:4-15.
-
(2014)
Eng. Life Sci.
, vol.14
, pp. 4-15
-
-
Liu, N.1
Zang, R.2
Yang, S.T.3
Li, Y.4
-
82
-
-
75349085710
-
Development of scalable culture systems for human embryonic stem cells
-
Azarin S.M., Palecek S.P. Development of scalable culture systems for human embryonic stem cells. Biochem. Eng. J. 2010, 48:378-384.
-
(2010)
Biochem. Eng. J.
, vol.48
, pp. 378-384
-
-
Azarin, S.M.1
Palecek, S.P.2
-
83
-
-
84890196247
-
Engineering stem cell fate with biochemical and biomechanical properties of microcarriers
-
Sart S., Agathos S.N., Li Y. Engineering stem cell fate with biochemical and biomechanical properties of microcarriers. Biotechnol. Prog. 2013, 29:1354-1366.
-
(2013)
Biotechnol. Prog.
, vol.29
, pp. 1354-1366
-
-
Sart, S.1
Agathos, S.N.2
Li, Y.3
-
84
-
-
84913541357
-
Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications
-
in press
-
Sart S., Tsai A.-C., Li Y., Ma T. Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications. Tissue Eng. Part B 2013, in press. 10.1089/ten.TEB.2013.0537.
-
(2013)
Tissue Eng. Part B
-
-
Sart, S.1
Tsai, A.-C.2
Li, Y.3
Ma, T.4
-
85
-
-
77955000681
-
Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential
-
Frith J.E., Thomson B., Genever P.G. Dynamic three-dimensional culture methods enhance mesenchymal stem cell properties and increase therapeutic potential. Tissue Eng. Part C 2010, 16:735-749.
-
(2010)
Tissue Eng. Part C
, vol.16
, pp. 735-749
-
-
Frith, J.E.1
Thomson, B.2
Genever, P.G.3
-
86
-
-
60849086260
-
Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation
-
Bratt-Leal A.M., Carpenedo R.L., McDevitt T.C. Engineering the embryoid body microenvironment to direct embryonic stem cell differentiation. Biotechnol. Prog. 2009, 25:43-51.
-
(2009)
Biotechnol. Prog.
, vol.25
, pp. 43-51
-
-
Bratt-Leal, A.M.1
Carpenedo, R.L.2
McDevitt, T.C.3
-
87
-
-
84879555644
-
Modulation of mesenchymal stem cell actin organization on conventional microcarriers for proliferation and differentiation in stirred bioreactors
-
Sart S., Errachid A., Schneider Y.J., Agathos S.N. Modulation of mesenchymal stem cell actin organization on conventional microcarriers for proliferation and differentiation in stirred bioreactors. J. Tissue Eng. Regener. Med. 2013, 7:537-551.
-
(2013)
J. Tissue Eng. Regener. Med.
, vol.7
, pp. 537-551
-
-
Sart, S.1
Errachid, A.2
Schneider, Y.J.3
Agathos, S.N.4
-
88
-
-
84876504019
-
Microfibrous carriers for integrated expansion and neural differentiation of embryonic stem cells in suspension bioreactor
-
Liu N., Li Y., Yang S.T. Microfibrous carriers for integrated expansion and neural differentiation of embryonic stem cells in suspension bioreactor. Biochem. Eng. J. 2013, 75:55-63.
-
(2013)
Biochem. Eng. J.
, vol.75
, pp. 55-63
-
-
Liu, N.1
Li, Y.2
Yang, S.T.3
-
89
-
-
84881614164
-
Three-dimensional neural differentiation of embryonic stem cells with ACM induction in microfibrous matrices in bioreactors
-
Liu N., Ouyang A., Li Y., Yang S.T. Three-dimensional neural differentiation of embryonic stem cells with ACM induction in microfibrous matrices in bioreactors. Biotechnol. Prog. 2013, 29:1013-1022.
-
(2013)
Biotechnol. Prog.
, vol.29
, pp. 1013-1022
-
-
Liu, N.1
Ouyang, A.2
Li, Y.3
Yang, S.T.4
-
90
-
-
57349132610
-
Improvement of culture conditions of human embryoid bodies using a controlled perfused and dialyzed bioreactor system
-
Come J., Nissan X., Aubry L., Tournois J., Girard M., Perrier A.L., Peschanski M., Cailleret M. Improvement of culture conditions of human embryoid bodies using a controlled perfused and dialyzed bioreactor system. Tissue Eng. Part C 2008, 14:289-298.
-
(2008)
Tissue Eng. Part C
, vol.14
, pp. 289-298
-
-
Come, J.1
Nissan, X.2
Aubry, L.3
Tournois, J.4
Girard, M.5
Perrier, A.L.6
Peschanski, M.7
Cailleret, M.8
-
91
-
-
77953630542
-
The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches
-
Das R., Jahr H., van Osch G.J., Farrell E. The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approaches. Tissue Eng. Part B 2010, 16:159-168.
-
(2010)
Tissue Eng. Part B
, vol.16
, pp. 159-168
-
-
Das, R.1
Jahr, H.2
van Osch, G.J.3
Farrell, E.4
-
92
-
-
84861019195
-
Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells
-
Zhang J., Nuebel E., Wisidagama D.R., Setoguchi K., Hong J.S., Van Horn C.M., Imam S.S., Vergnes L., Malone C.S., Koehler C.M., Teitell M.A. Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells. Nat. Protoc. 2012, 7:1068-1085.
-
(2012)
Nat. Protoc.
, vol.7
, pp. 1068-1085
-
-
Zhang, J.1
Nuebel, E.2
Wisidagama, D.R.3
Setoguchi, K.4
Hong, J.S.5
Van Horn, C.M.6
Imam, S.S.7
Vergnes, L.8
Malone, C.S.9
Koehler, C.M.10
Teitell, M.A.11
-
93
-
-
79953152705
-
Real time monitoring of multiple parameters in mammalian cell culture bioreactors using an in-line Raman spectroscopy probe
-
Abu-Absi N.R., Kenty B.M., Cuellar M.E., Borys M.C., Sakhamuri S., Strachan D.J., Hausladen M.C., Li Z.J. Real time monitoring of multiple parameters in mammalian cell culture bioreactors using an in-line Raman spectroscopy probe. Biotechnol. Bioeng. 2011, 108:1215-1221.
-
(2011)
Biotechnol. Bioeng.
, vol.108
, pp. 1215-1221
-
-
Abu-Absi, N.R.1
Kenty, B.M.2
Cuellar, M.E.3
Borys, M.C.4
Sakhamuri, S.5
Strachan, D.J.6
Hausladen, M.C.7
Li, Z.J.8
-
94
-
-
77957329646
-
Influence of culture parameters on ear mesenchymal stem cells expanded on microcarriers
-
Sart S., Schneider Y.J., Agathos S.N. Influence of culture parameters on ear mesenchymal stem cells expanded on microcarriers. J. Biotechnol. 2010, 150:149-160.
-
(2010)
J. Biotechnol.
, vol.150
, pp. 149-160
-
-
Sart, S.1
Schneider, Y.J.2
Agathos, S.N.3
-
95
-
-
34548134850
-
Bioreactor development for stem cell expansion and controlled differentiation
-
King J.A., Miller W.M. Bioreactor development for stem cell expansion and controlled differentiation. Curr. Opin. Chem. Biol. 2007, 11:394-398.
-
(2007)
Curr. Opin. Chem. Biol.
, vol.11
, pp. 394-398
-
-
King, J.A.1
Miller, W.M.2
-
96
-
-
53049108615
-
The systematic production of cells for cell therapies
-
Kirouac D.C., Zandstra P.W. The systematic production of cells for cell therapies. Cell Stem Cell 2008, 3:369-381.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 369-381
-
-
Kirouac, D.C.1
Zandstra, P.W.2
-
97
-
-
80054017005
-
Optimization of flowrate for expansion of human embryonic stem cells in perfusion microbioreactors
-
Titmarsh D., Hidalgo A., Turner J., Wolvetang E., Cooper-White J. Optimization of flowrate for expansion of human embryonic stem cells in perfusion microbioreactors. Biotechnol. Bioeng. 2011, 108:2894-2904.
-
(2011)
Biotechnol. Bioeng.
, vol.108
, pp. 2894-2904
-
-
Titmarsh, D.1
Hidalgo, A.2
Turner, J.3
Wolvetang, E.4
Cooper-White, J.5
-
98
-
-
52049085840
-
Expansion of mesenchymal stem cells using a microcarrier-based cultivation system: growth and metabolism
-
Schop D., Janssen F.W., Borgart E., de Bruijn J.D., van Dijkhuizen-Radersma R. Expansion of mesenchymal stem cells using a microcarrier-based cultivation system: growth and metabolism. J. Tissue Eng. Regener. Med. 2008, 2:126-135.
-
(2008)
J. Tissue Eng. Regener. Med.
, vol.2
, pp. 126-135
-
-
Schop, D.1
Janssen, F.W.2
Borgart, E.3
de Bruijn, J.D.4
van Dijkhuizen-Radersma, R.5
-
99
-
-
67349266968
-
Culture pH and osmolality influence proliferation and embryoid body yields of murine embryonic stem cells
-
Chaudhry M.A., Bowen B.D., Piret J.M. Culture pH and osmolality influence proliferation and embryoid body yields of murine embryonic stem cells. Biochem. Eng. J. 2009, 45:126-135.
-
(2009)
Biochem. Eng. J.
, vol.45
, pp. 126-135
-
-
Chaudhry, M.A.1
Bowen, B.D.2
Piret, J.M.3
-
100
-
-
73349136774
-
Effects of flow shear stress and mass transport on the construction of a large-scale tissue-engineered bone in a perfusion bioreactor
-
Li D., Tang T., Lu J., Dai K. Effects of flow shear stress and mass transport on the construction of a large-scale tissue-engineered bone in a perfusion bioreactor. Tissue Eng. Part A 2009, 15:2773-2783.
-
(2009)
Tissue Eng. Part A
, vol.15
, pp. 2773-2783
-
-
Li, D.1
Tang, T.2
Lu, J.3
Dai, K.4
-
101
-
-
77955057824
-
Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control
-
Serra M., Brito C., Sousa M.F., Jensen J., Tostoes R., Clemente J., Strehl R., Hyllner J., Carrondo M.J., Alves P.M. Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control. J. Biotechnol. 2010, 148:208-215.
-
(2010)
J. Biotechnol.
, vol.148
, pp. 208-215
-
-
Serra, M.1
Brito, C.2
Sousa, M.F.3
Jensen, J.4
Tostoes, R.5
Clemente, J.6
Strehl, R.7
Hyllner, J.8
Carrondo, M.J.9
Alves, P.M.10
-
102
-
-
84855384168
-
Adipogenesis of human adipose-derived stem cells within three-dimensional hollow fiber-based bioreactors
-
Gerlach J.C., Lin Y.C., Brayfield C.A., Minteer D.M., Li H., Rubin J.P., Marra K.G. Adipogenesis of human adipose-derived stem cells within three-dimensional hollow fiber-based bioreactors. Tissue Eng. Part C 2012, 18:54-61.
-
(2012)
Tissue Eng. Part C
, vol.18
, pp. 54-61
-
-
Gerlach, J.C.1
Lin, Y.C.2
Brayfield, C.A.3
Minteer, D.M.4
Li, H.5
Rubin, J.P.6
Marra, K.G.7
-
103
-
-
77952515152
-
High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways
-
Ryu J.M., Lee M.Y., Yun S.P., Han H.J. High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways. J. Cell. Physiol. 2010, 224:59-70.
-
(2010)
J. Cell. Physiol.
, vol.224
, pp. 59-70
-
-
Ryu, J.M.1
Lee, M.Y.2
Yun, S.P.3
Han, H.J.4
-
104
-
-
58249090413
-
Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor
-
Niebruegge S., Bauwens C.L., Peerani R., Thavandiran N., Masse S., Sevaptisidis E., Nanthakumar K., Woodhouse K., Husain M., Kumacheva E., Zandstra P.W. Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor. Biotechnol. Bioeng. 2009, 102:493-507.
-
(2009)
Biotechnol. Bioeng.
, vol.102
, pp. 493-507
-
-
Niebruegge, S.1
Bauwens, C.L.2
Peerani, R.3
Thavandiran, N.4
Masse, S.5
Sevaptisidis, E.6
Nanthakumar, K.7
Woodhouse, K.8
Husain, M.9
Kumacheva, E.10
Zandstra, P.W.11
-
105
-
-
79955462003
-
Hepatic differentiation of human embryonic stem cells is promoted by three-dimensional dynamic perfusion culture conditions
-
Miki T., Ring A., Gerlach J. Hepatic differentiation of human embryonic stem cells is promoted by three-dimensional dynamic perfusion culture conditions. Tissue Eng. Part C 2011, 17:557-568.
-
(2011)
Tissue Eng. Part C
, vol.17
, pp. 557-568
-
-
Miki, T.1
Ring, A.2
Gerlach, J.3
-
106
-
-
84868527766
-
Rotating microgravity-bioreactor cultivation enhances the hepatic differentiation of mouse embryonic stem cells on biodegradable polymer scaffolds
-
Wang Y., Zhang Y., Zhang S., Peng G., Liu T., Li Y., Xiang D., Wassler M.J., Shelat H.S., Geng Y. Rotating microgravity-bioreactor cultivation enhances the hepatic differentiation of mouse embryonic stem cells on biodegradable polymer scaffolds. Tissue Eng. Part A 2012, 18:2376-2385.
-
(2012)
Tissue Eng. Part A
, vol.18
, pp. 2376-2385
-
-
Wang, Y.1
Zhang, Y.2
Zhang, S.3
Peng, G.4
Liu, T.5
Li, Y.6
Xiang, D.7
Wassler, M.J.8
Shelat, H.S.9
Geng, Y.10
-
107
-
-
84888618721
-
Efficient large-scale generation of functional hepatocytes from mouse embryonic stem cells grown in a rotating bioreactor with exogenous growth factors and hormones
-
Zhang S., Zhang Y., Chen L., Liu T., Li Y., Wang Y., Geng Y. Efficient large-scale generation of functional hepatocytes from mouse embryonic stem cells grown in a rotating bioreactor with exogenous growth factors and hormones. Stem Cell Res. Ther. 2013, 4:145.
-
(2013)
Stem Cell Res. Ther.
, vol.4
, pp. 145
-
-
Zhang, S.1
Zhang, Y.2
Chen, L.3
Liu, T.4
Li, Y.5
Wang, Y.6
Geng, Y.7
-
108
-
-
84896857851
-
A novel axial-stress bioreactor system combined with a substance exchanger for tissue engineering of 3D constructs
-
Li S.T., Liu Y., Zhou Q., Lue R.F., Song L., Dong S.W., Guo P., Kopjar B. A novel axial-stress bioreactor system combined with a substance exchanger for tissue engineering of 3D constructs. Tissue Eng. Part C 2013, 10.1089/ten.tec.2013.0173.
-
(2013)
Tissue Eng. Part C
-
-
Li, S.T.1
Liu, Y.2
Zhou, Q.3
Lue, R.F.4
Song, L.5
Dong, S.W.6
Guo, P.7
Kopjar, B.8
-
109
-
-
77955358863
-
Serum-free scaled up expansion and differentiation of murine embryonic stem cells to osteoblasts in suspension bioreactors
-
Alfred R., Gareau T., Krawetz R., Rancourt D., Kallos M.S. Serum-free scaled up expansion and differentiation of murine embryonic stem cells to osteoblasts in suspension bioreactors. Biotechnol. Bioeng. 2010, 106:829-840.
-
(2010)
Biotechnol. Bioeng.
, vol.106
, pp. 829-840
-
-
Alfred, R.1
Gareau, T.2
Krawetz, R.3
Rancourt, D.4
Kallos, M.S.5
-
110
-
-
84871833218
-
High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations
-
Baptista R.P., Fluri D.A., Zandstra P.W. High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations. Biotechnol. Bioeng. 2013, 110:648-655.
-
(2013)
Biotechnol. Bioeng.
, vol.110
, pp. 648-655
-
-
Baptista, R.P.1
Fluri, D.A.2
Zandstra, P.W.3
-
111
-
-
78649643876
-
Simple modular bioreactors for tissue engineering: a system for characterization of oxygen gradients, human mesenchymal stem cell differentiation, and prevascularization
-
Lovett M., Rockwood D., Baryshyan A., Kaplan D.L. Simple modular bioreactors for tissue engineering: a system for characterization of oxygen gradients, human mesenchymal stem cell differentiation, and prevascularization. Tissue Eng. Part C 2010, 16:1565-1573.
-
(2010)
Tissue Eng. Part C
, vol.16
, pp. 1565-1573
-
-
Lovett, M.1
Rockwood, D.2
Baryshyan, A.3
Kaplan, D.L.4
|