Rotating microgravity-bioreactor cultivation enhances the hepatic differentiation of mouse embryonic stem cells on biodegradable polymer scaffolds

Tissue Engineering - Part A

Volumn 18, Issue 21-22, 2012, Pages 2376-2385

  Wang, Yingjie ^a,b   Zhang, Yunping ^b,c   Zhang, Shichang ^a   Peng, Guangyong ^d   Liu, Tao ^a   Li, Yangxin ^b   Xiang, Dedong ^a   Wassler, Michael J ^b   Shelat, Harnath S ^b   Geng, Yongjian ^b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS   (United States)

^c JaoTong University   (China)

^d SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOARTIFICIAL LIVER; BIODEGRADABLE POLYMER SCAFFOLDS; CULTURE SYSTEMS; CYTOCHROME P450; DIFFERENTIATED CELLS; EMBRYONIC STEM CELLS; ES CELLS; EXOGENOUS GROWTH; FLOW-CYTOMETRIC ANALYSIS; HEPATIC DIFFERENTIATION; HEPATOCYTES; IMMUNOSTAINING; IN-VIVO; LIVER CELLS; LIVER TISSUE; LOW DENSITY LIPOPROTEINS; MORPHOLOGIC CHARACTERISTICS; MOUSE EMBRYONIC STEM CELLS; PLURIPOTENT; SIMULATED MICROGRAVITY; SOMATIC CELLS; WESTERN BLOTS;

ARTIFICIAL ORGANS; BIOCONVERSION; BIOREACTORS; CELL CULTURE; CELL ENGINEERING; MAMMALS; MICROGRAVITY; MICROGRAVITY PROCESSING; POLYMERASE CHAIN REACTION; STEM CELLS; THREE DIMENSIONAL COMPUTER GRAPHICS; TISSUE; TRANSCRIPTION;

SCAFFOLDS (BIOLOGY);

MUS;

ALBUMINOID; CYTOCHROME P450; LACTIC ACID; LOW DENSITY LIPOPROTEIN; POLYLACTIC ACID; POLYMER; TISSUE SCAFFOLD;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; BIOREACTOR; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; EMBRYOID BODY; EMBRYONIC STEM CELL; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; INSTRUMENTATION; LIVER; METABOLISM; MOUSE; MOUSE MUTANT; ROTATION; TRANSPLANTATION; ULTRASTRUCTURE; WEIGHTLESSNESS;

ALBUMINS; ANIMALS; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SHAPE; CYTOCHROME P-450 ENZYME SYSTEM; EMBRYOID BODIES; EMBRYONIC STEM CELLS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; LACTIC ACID; LIPOPROTEINS, LDL; LIVER; MICE; MICE, SCID; ORGAN SPECIFICITY; POLYMERS; ROTATION; TISSUE SCAFFOLDS; WEIGHTLESSNESS;

EID: 84868527766     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2012.0097     Document Type: Article

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