Reactive oxygen species enhance differentiation of human embryonic stem cells into mesendodermal lineage

Experimental and Molecular Medicine

Volumn 42, Issue 3, 2010, Pages 175-186

  Ji, Ae Ri ^a,b   Ku, Seung Yup ^a,b   Cho, Myung Soo ^c   Kim, Yoon Young ^b   Kim, Yong Jin ^a   Oh, Sun Kyung ^b   Kim, Seok Hyun ^a,b   Moon, Shin Yong ^a,b   Choi, Young Min ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Jeil Pharmaceutical Co Ltd   (South Korea)

Author keywords

Cell differentiation; Embryonic stem cells; Mitogen activated protein kinases; Reactive oxygen species

Indexed keywords

BUTHIONINE SULFOXIMINE; HEPATOCYTE NUCLEAR FACTOR 3BETA; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR NKX2.2; TRANSCRIPTION FACTOR PDX 1; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; BIOLOGICAL MARKER; SCAVENGER;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; DOSE RESPONSE; DOWN REGULATION; EMBRYONIC STEM CELL; ENDODERM; ENVIRONMENTAL FACTOR; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INDUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MESODERM; PHASE CONTRAST MICROSCOPY; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL EMBRYO; CELL LINE; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM;

BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; CELLS, CULTURED; DOWN-REGULATION; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; ENDODERM; ENZYME ACTIVATION; FREE RADICAL SCAVENGERS; HUMANS; MESODERM; MITOGEN-ACTIVATED PROTEIN KINASES; PLURIPOTENT STEM CELLS; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 77950523031     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2010.42.3.018     Document Type: Article

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