-
1
-
-
0034983625
-
Multilineage differentiation from human embryonic stem cell lines
-
Odorico JS, DS Kaufman and JA Thomson. (2001). Multilineage differentiation from human embryonic stem cell lines. Stem Cells 19:193-204.
-
(2001)
Stem Cells
, vol.19
, pp. 193-204
-
-
Odorico, J.S.1
Kaufman, D.S.2
Thomson, J.A.3
-
2
-
-
4544288228
-
Derivation, growth and applications of human embryonic stem cells
-
Stojkovic M, M Lako, T Strachan and A Murdoch. (2004). Derivation, growth and applications of human embryonic stem cells. Reproduction 128:259-267.
-
(2004)
Reproduction
, vol.128
, pp. 259-267
-
-
Stojkovic, M.1
Lako, M.2
Strachan, T.3
Murdoch, A.4
-
3
-
-
33845315254
-
Human embryonic stem cells: A journey beyond cell replacement therapies
-
Menendez P, C Bueno and L Wang. (2006). Human embryonic stem cells: a journey beyond cell replacement therapies. Cytotherapy 8:530-541.
-
(2006)
Cytotherapy
, vol.8
, pp. 530-541
-
-
Menendez, P.1
Bueno, C.2
Wang, L.3
-
4
-
-
0034484069
-
Human embryonic stem cell technology
-
Jones JM and JA Thomson. (2000). Human embryonic stem cell technology. Semin Reprod Med 18:219-223.
-
(2000)
Semin Reprod Med
, vol.18
, pp. 219-223
-
-
Jones, J.M.1
Thomson, J.A.2
-
5
-
-
0036245050
-
Derivation and spontaneous differentiation of human embryonic stem cells
-
Amit M and J Itskovitz-Eldor. (2002). Derivation and spontaneous differentiation of human embryonic stem cells. J Anat 200:225-232.
-
(2002)
J Anat
, vol.200
, pp. 225-232
-
-
Amit, M.1
Itskovitz-Eldor, J.2
-
6
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson JA, J Itskovitz-Eldor, SS Shapiro, MA Waknitz, JJ Swiergiel, VS Marshall and JM Jones. (1998). Embryonic stem cell lines derived from human blastocysts. Science 282:1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
7
-
-
0027756119
-
Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits
-
Fischer B and BD Bavister. (1993). Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits. J Reprod Fertil 99:673-679.
-
(1993)
J Reprod Fertil
, vol.99
, pp. 673-679
-
-
Fischer, B.1
Bavister, B.D.2
-
8
-
-
33748611648
-
Observations on intrauterine oxygen tension measured by fibre-optic microsensors
-
Ottosen LD, J Hindkaer, M Husth, DE Petersen, J Kirk and HJ Ingerslev. (2006). Observations on intrauterine oxygen tension measured by fibre-optic microsensors. Reprod Biomed Online 13:380-385.
-
(2006)
Reprod Biomed Online
, vol.13
, pp. 380-385
-
-
Ottosen, L.D.1
Hindkaer, J.2
Husth, M.3
Petersen, D.E.4
Kirk, J.5
Ingerslev, H.J.6
-
9
-
-
16344380951
-
Low O2 tensions and the prevention of differentiation of hES cells
-
Ezashi T, P Das and RM Roberts. (2005). Low O2 tensions and the prevention of differentiation of hES cells. Proc Natl Acad Sci USA 102:4783-4788.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4783-4788
-
-
Ezashi, T.1
Das, P.2
Roberts, R.M.3
-
10
-
-
1842416574
-
Oxygen(es) and the hypoxia-inducible factor-1
-
Wenger RH and M Gassmann. (1997). Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 378:609-616.
-
(1997)
Biol Chem
, vol.378
, pp. 609-616
-
-
Wenger, R.H.1
Gassmann, M.2
-
11
-
-
21344438419
-
Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1)
-
Greijer AE, P van der Groep, D Kemming, A Shvarts, GL Semenza, GA Meijer, MA van de Wiel, JA Belien, PJ van Diest and E van der Wall. (2005). Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1). J Pathol 206:291-304.
-
(2005)
J Pathol
, vol.206
, pp. 291-304
-
-
Greijer, A.E.1
van der Groep, P.2
Kemming, D.3
Shvarts, A.4
Semenza, G.L.5
Meijer, G.A.6
van de Wiel, M.A.7
Belien, J.A.8
van Diest, P.J.9
van der Wall, E.10
-
12
-
-
0028068606
-
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1
-
Semenza GL, PH Roth, HM Fang and GL Wang. (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 269:23757-23763.
-
(1994)
J Biol Chem
, vol.269
, pp. 23757-23763
-
-
Semenza, G.L.1
Roth, P.H.2
Fang, H.M.3
Wang, G.L.4
-
13
-
-
4544354541
-
Oxygen-regulated gene expression in bovine blastocysts
-
Harvey AJ, KL Kind, M Pantaleon, DT Armstrong and JG Thompson. (2004). Oxygen-regulated gene expression in bovine blastocysts. Biol Reprod 71:1108-1119.
-
(2004)
Biol Reprod
, vol.71
, pp. 1108-1119
-
-
Harvey, A.J.1
Kind, K.L.2
Pantaleon, M.3
Armstrong, D.T.4
Thompson, J.G.5
-
14
-
-
15444342958
-
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
-
Iyer NV, LE Kotch, F Agani, SW Leung, E Laughner, RH Wenger, M Gassmann, JD Gearhart, AM Lawler, AY Yu and GL Semenza. (1998). Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev 12:149-162.
-
(1998)
Genes Dev
, vol.12
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
15
-
-
34247527730
-
Hypoxia-inducible factors, stem cells, and cancer
-
Keith B and MC Simon. (2007). Hypoxia-inducible factors, stem cells, and cancer. Cell 129:465-472.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
16
-
-
0030892448
-
Effects of gas atmosphere, platelet-derived growth factor and leukemia inhibitory factor on cell numbers of rabbit embryos cultured in a protein-free medium
-
Giles JR and RH Foote. (1997). Effects of gas atmosphere, platelet-derived growth factor and leukemia inhibitory factor on cell numbers of rabbit embryos cultured in a protein-free medium. Reprod Nutr Dev 37:97-104.
-
(1997)
Reprod Nutr Dev
, vol.37
, pp. 97-104
-
-
Giles, J.R.1
Foote, R.H.2
-
17
-
-
28344444966
-
The impact of oxygen tension on developmental competence of post-thaw human embryos
-
Petersen A, AL Mikkelsen and S Lindenberg. (2005). The impact of oxygen tension on developmental competence of post-thaw human embryos. Acta Obstet Gynecol Scand 84:1181-1184.
-
(2005)
Acta Obstet Gynecol Scand
, vol.84
, pp. 1181-1184
-
-
Petersen, A.1
Mikkelsen, A.L.2
Lindenberg, S.3
-
18
-
-
0025282307
-
Effect of oxygen concentration on in-vitro development of preimplantation sheep and cattle embryos
-
Thompson JG, AC Simpson, PA Pugh, PE Donnelly and HR Tervit. (1990). Effect of oxygen concentration on in-vitro development of preimplantation sheep and cattle embryos. J Reprod Fertil 89:573-578.
-
(1990)
J Reprod Fertil
, vol.89
, pp. 573-578
-
-
Thompson, J.G.1
Simpson, A.C.2
Pugh, P.A.3
Donnelly, P.E.4
Tervit, H.R.5
-
19
-
-
16844384709
-
The effect of oxygen tension on porcine embryonic development is dependent on embryo type
-
Booth PJ, P Holm and H Callesen. (2005). The effect of oxygen tension on porcine embryonic development is dependent on embryo type. Theriogenology 63:2040-2052.
-
(2005)
Theriogenology
, vol.63
, pp. 2040-2052
-
-
Booth, P.J.1
Holm, P.2
Callesen, H.3
-
20
-
-
33750597373
-
-
Rinaudo PF, G Giritharan, S Talbi, AT Dobson and RM Schultz. (2006). Effects of oxygen tension on gene expression in preimplantation mouse embryos. Fertil Steril 86 Suppl 4:1252-1265, e1251-1236.
-
Rinaudo PF, G Giritharan, S Talbi, AT Dobson and RM Schultz. (2006). Effects of oxygen tension on gene expression in preimplantation mouse embryos. Fertil Steril 86 Suppl 4:1252-1265, e1251-1236.
-
-
-
-
21
-
-
33644747418
-
HIF-2alpha regulates Oct-4: Effects of hypoxia on stem cell function, embryonic development, and tumor growth
-
Covello KL, J Kehler, H Yu, JD Gordan, AM Arsham, CJ Hu, PA Labosky, MC Simon and B Keith. (2006). HIF-2alpha regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth. Genes Dev 20:557-570.
-
(2006)
Genes Dev
, vol.20
, pp. 557-570
-
-
Covello, K.L.1
Kehler, J.2
Yu, H.3
Gordan, J.D.4
Arsham, A.M.5
Hu, C.J.6
Labosky, P.A.7
Simon, M.C.8
Keith, B.9
-
22
-
-
33646248422
-
Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells
-
Hu CJ, S Iyer, A Sataur, KL Covello, LA Chodosh and MC Simon. (2006). Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells. Mol Cell Biol 26:3514-3526.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3514-3526
-
-
Hu, C.J.1
Iyer, S.2
Sataur, A.3
Covello, K.L.4
Chodosh, L.A.5
Simon, M.C.6
-
23
-
-
0037520693
-
Stem cell pluripotency and transcription factor Oct4
-
Pan GJ, ZY Chang, HR Scholer and D Pei. (2002). Stem cell pluripotency and transcription factor Oct4. Cell Res 12:321-329.
-
(2002)
Cell Res
, vol.12
, pp. 321-329
-
-
Pan, G.J.1
Chang, Z.Y.2
Scholer, H.R.3
Pei, D.4
-
24
-
-
0034794417
-
Feeder-free growth of undifferentiated human embryonic stem cells
-
Xu C, MS Inokuma, J Denham, K Golds, P Kundu, JD Gold and MK Carpenter. (2001). Feeder-free growth of undifferentiated human embryonic stem cells. Nat Biotechnol 19:971-974.
-
(2001)
Nat Biotechnol
, vol.19
, pp. 971-974
-
-
Xu, C.1
Inokuma, M.S.2
Denham, J.3
Golds, K.4
Kundu, P.5
Gold, J.D.6
Carpenter, M.K.7
-
25
-
-
26444454986
-
A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array
-
Harbig J, R Sprinkle and SA Enkemann. (2005). A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array. Nucleic Acids Res 33:e31.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Harbig, J.1
Sprinkle, R.2
Enkemann, S.A.3
-
26
-
-
27244450862
-
Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies
-
Bhattacharya B, J Cai, Y Luo, T Miura, J Mejido, SN Brimble, X Zeng, TC Schulz, MS Rao and RK Puri. (2005). Comparison of the gene expression profile of undifferentiated human embryonic stem cell lines and differentiating embryoid bodies. BMC Dev Biol 5:22.
-
(2005)
BMC Dev Biol
, vol.5
, pp. 22
-
-
Bhattacharya, B.1
Cai, J.2
Luo, Y.3
Miura, T.4
Mejido, J.5
Brimble, S.N.6
Zeng, X.7
Schulz, T.C.8
Rao, M.S.9
Puri, R.K.10
-
27
-
-
33744989977
-
Assessing self-renewal and differentiation in human embryonic stem cell lines
-
Cai J, J Chen, Y Liu, T Miura, Y Luo, JF Loring, WJ Freed, MS Rao and X Zeng. (2006). Assessing self-renewal and differentiation in human embryonic stem cell lines. Stem Cells 24:516-530.
-
(2006)
Stem Cells
, vol.24
, pp. 516-530
-
-
Cai, J.1
Chen, J.2
Liu, Y.3
Miura, T.4
Luo, Y.5
Loring, J.F.6
Freed, W.J.7
Rao, M.S.8
Zeng, X.9
-
28
-
-
33745834792
-
Profiling of differentially expressed genes in human stem cells by cDNA microarray
-
Kim CG, JJ Lee, DY Jung, J Jeon, HS Heo, HC Kang, JH Shin, YS Cho, KJ Cha, CG Kim, BR Do, KS Kim and HS Kim. (2006). Profiling of differentially expressed genes in human stem cells by cDNA microarray. Mol Cells 21:343-355.
-
(2006)
Mol Cells
, vol.21
, pp. 343-355
-
-
Kim, C.G.1
Lee, J.J.2
Jung, D.Y.3
Jeon, J.4
Heo, H.S.5
Kang, H.C.6
Shin, J.H.7
Cho, Y.S.8
Cha, K.J.9
Kim, C.G.10
Do, B.R.11
Kim, K.S.12
Kim, H.S.13
-
29
-
-
8744261589
-
Comparative transcriptional profiling of two human embryonic stem cell lines
-
Rao RR, JD Calhoun, X Qin, R Rekaya, JK Clark and SL Stice. (2004). Comparative transcriptional profiling of two human embryonic stem cell lines. Biotechnol Bioeng 88:273-286.
-
(2004)
Biotechnol Bioeng
, vol.88
, pp. 273-286
-
-
Rao, R.R.1
Calhoun, J.D.2
Qin, X.3
Rekaya, R.4
Clark, J.K.5
Stice, S.L.6
-
30
-
-
4544385734
-
Gene expression profiling of embryonic stem cells leads to greater understanding of pluripotency and early developmental events
-
Rao RR and SL Stice. (2004). Gene expression profiling of embryonic stem cells leads to greater understanding of pluripotency and early developmental events. Biol Reprod 71:1772-1778.
-
(2004)
Biol Reprod
, vol.71
, pp. 1772-1778
-
-
Rao, R.R.1
Stice, S.L.2
-
31
-
-
1842494625
-
Properties of pluripotent human embryonic stem cells BG01 and BG02
-
Zeng X, T Miura, Y Luo, B Bhattacharya, B Condie, J Chen, I Ginis, I Lyons, J Mejido, RK Puri, MS Rao and WJ Freed. (2004). Properties of pluripotent human embryonic stem cells BG01 and BG02. Stem Cells 22:292-312.
-
(2004)
Stem Cells
, vol.22
, pp. 292-312
-
-
Zeng, X.1
Miura, T.2
Luo, Y.3
Bhattacharya, B.4
Condie, B.5
Chen, J.6
Ginis, I.7
Lyons, I.8
Mejido, J.9
Puri, R.K.10
Rao, M.S.11
Freed, W.J.12
-
32
-
-
19944426528
-
Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001
-
Brimble SN, X Zeng, DA Weiler, Y Luo, Y Liu, IG Lyons, WJ Freed, AJ Robins, MS Rao and TC Schulz. (2004). Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001. Stem Cells Dev 13:585-597.
-
(2004)
Stem Cells Dev
, vol.13
, pp. 585-597
-
-
Brimble, S.N.1
Zeng, X.2
Weiler, D.A.3
Luo, Y.4
Liu, Y.5
Lyons, I.G.6
Freed, W.J.7
Robins, A.J.8
Rao, M.S.9
Schulz, T.C.10
-
33
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer LA, TI Lee, MF Cole, SE Johnstone, SS Levine, JP Zucker, MG Guenther, RM Kumar, HL Murray, RG Jenner, DK Gifford, DA Melton, R Jaenisch and RA Young. (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122:947-956.
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
Lee, T.I.2
Cole, M.F.3
Johnstone, S.E.4
Levine, S.S.5
Zucker, J.P.6
Guenther, M.G.7
Kumar, R.M.8
Murray, H.L.9
Jenner, R.G.10
Gifford, D.K.11
Melton, D.A.12
Jaenisch, R.13
Young, R.A.14
-
34
-
-
33645381936
-
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
-
Loh YH, Q Wu, JL Chew, VB Vega, W Zhang, X Chen, G Bourque, J George, B Leong, J Liu, KY Wong, KW Sung, CW Lee, XD Zhao, KP Chiu, L Lipovich, VA Kuznetsov, P Robson, LW Stanton, CL Wei, Y Ruan, B Lim and HH Ng. (2006). The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38:431-440.
-
(2006)
Nat Genet
, vol.38
, pp. 431-440
-
-
Loh, Y.H.1
Wu, Q.2
Chew, J.L.3
Vega, V.B.4
Zhang, W.5
Chen, X.6
Bourque, G.7
George, J.8
Leong, B.9
Liu, J.10
Wong, K.Y.11
Sung, K.W.12
Lee, C.W.13
Zhao, X.D.14
Chiu, K.P.15
Lipovich, L.16
Kuznetsov, V.A.17
Robson, P.18
Stanton, L.W.19
Wei, C.L.20
Ruan, Y.21
Lim, B.22
Ng, H.H.23
more..
-
35
-
-
33751092246
-
A protein interaction network for pluripotency of embryonic stem cells
-
Wang J, S Rao, J Chu, X Shen, DN Levasseur, TW Theunissen and SH Orkin. (2006). A protein interaction network for pluripotency of embryonic stem cells. Nature 444:364-368.
-
(2006)
Nature
, vol.444
, pp. 364-368
-
-
Wang, J.1
Rao, S.2
Chu, J.3
Shen, X.4
Levasseur, D.N.5
Theunissen, T.W.6
Orkin, S.H.7
-
36
-
-
0032582513
-
Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
-
Nichols J, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, I Chambers, H Scholer and A Smith. (1998). Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 95:379-391.
-
(1998)
Cell
, vol.95
, pp. 379-391
-
-
Nichols, J.1
Zevnik, B.2
Anastassiadis, K.3
Niwa, H.4
Klewe-Nebenius, D.5
Chambers, I.6
Scholer, H.7
Smith, A.8
-
37
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K, Y Tokuzawa, H Itoh, K Segawa, M Murakami, K Takahashi, M Maruyama, M Maeda and S Yamanaka. (2003). The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
Maruyama, M.7
Maeda, M.8
Yamanaka, S.9
-
38
-
-
0346250854
-
The transcriptome profile of human embryonic stem cells as defined by SAGE
-
Richards M, SP Tan, JH Tan, WK Chan and A Bongso. (2004). The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells 22:51-64.
-
(2004)
Stem Cells
, vol.22
, pp. 51-64
-
-
Richards, M.1
Tan, S.P.2
Tan, J.H.3
Chan, W.K.4
Bongso, A.5
-
39
-
-
0037227099
-
Multipotent cell lineages in early mouse development depend on SOX2 function
-
Avilion AA, SK Nicolis, LH Pevny, L Perez, N Vivian and R Lovell-Badge. (2003). Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 17:126-140.
-
(2003)
Genes Dev
, vol.17
, pp. 126-140
-
-
Avilion, A.A.1
Nicolis, S.K.2
Pevny, L.H.3
Perez, L.4
Vivian, N.5
Lovell-Badge, R.6
-
40
-
-
0031949215
-
Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site
-
Ben-Shushan E, JR Thompson, LJ Gudas and Y Bergman. (1998). Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site. Mol Cell Biol 18:1866-1878.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1866-1878
-
-
Ben-Shushan, E.1
Thompson, J.R.2
Gudas, L.J.3
Bergman, Y.4
-
41
-
-
16444384725
-
Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage
-
Armstrong L, G Saretzki, H Peters, I Wappler, J Evans, N Hole, T von Zglinicki and M Lako. (2005). Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage. Stem Cells 23:516-529.
-
(2005)
Stem Cells
, vol.23
, pp. 516-529
-
-
Armstrong, L.1
Saretzki, G.2
Peters, H.3
Wappler, I.4
Evans, J.5
Hole, N.6
von Zglinicki, T.7
Lako, M.8
-
43
-
-
33846917472
-
Analysis of OCT4 dependent transcriptional networks regulating self renewal and pluripotency in human embryonic stem cells
-
Babaie Y, R Herwig, B Greber, TC Brink, W Wruck, D Groth, H Lehrach, T Burdon and J Adjaye. (2007). Analysis of OCT4 dependent transcriptional networks regulating self renewal and pluripotency in human embryonic stem cells. Stem Cells 25:500-510.
-
(2007)
Stem Cells
, vol.25
, pp. 500-510
-
-
Babaie, Y.1
Herwig, R.2
Greber, B.3
Brink, T.C.4
Wruck, W.5
Groth, D.6
Lehrach, H.7
Burdon, T.8
Adjaye, J.9
-
44
-
-
7244240749
-
Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3
-
Besser D. (2004). Expression of nodal, lefty-a, and lefty-B in undifferentiated human embryonic stem cells requires activation of Smad2/3. J Biol Chem 279:45076-45084.
-
(2004)
J Biol Chem
, vol.279
, pp. 45076-45084
-
-
Besser, D.1
-
45
-
-
16244400050
-
TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
-
James D, AJ Levine, D Besser and A Hemmati-Brivanlou. (2005). TGFbeta/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells. Development 132:1273-1282.
-
(2005)
Development
, vol.132
, pp. 1273-1282
-
-
James, D.1
Levine, A.J.2
Besser, D.3
Hemmati-Brivanlou, A.4
-
46
-
-
27644486756
-
Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
-
Vallier L, M Alexander and RA Pedersen. (2005). Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells. J Cell Sci 118:4495-4509.
-
(2005)
J Cell Sci
, vol.118
, pp. 4495-4509
-
-
Vallier, L.1
Alexander, M.2
Pedersen, R.A.3
-
47
-
-
33645242374
-
TGF-beta 1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling
-
Kutz SM, CE Higgins, R Samarakoon, SP Higgins, RR Allen, L Qi and PJ Higgins. (2006). TGF-beta 1-induced PAI-1 expression is E box/USF-dependent and requires EGFR signaling. Exp Cell Res 312:1093-1105.
-
(2006)
Exp Cell Res
, vol.312
, pp. 1093-1105
-
-
Kutz, S.M.1
Higgins, C.E.2
Samarakoon, R.3
Higgins, S.P.4
Allen, R.R.5
Qi, L.6
Higgins, P.J.7
-
48
-
-
33845296149
-
The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer
-
Buck A, M Buchholz, M Wagner, G Adler, T Gress and V Ellenrieder. (2006). The tumor suppressor KLF11 mediates a novel mechanism in transforming growth factor beta-induced growth inhibition that is inactivated in pancreatic cancer. Mol Cancer Res 4:861-872.
-
(2006)
Mol Cancer Res
, vol.4
, pp. 861-872
-
-
Buck, A.1
Buchholz, M.2
Wagner, M.3
Adler, G.4
Gress, T.5
Ellenrieder, V.6
-
49
-
-
4544259610
-
Transcriptional profiling of initial differentiation events in human embryonic stem cells
-
Calhoun JD, RR Rao, S Warrenfeltz, R Rekaya, S Dalton, J McDonald and SL Stice. (2004). Transcriptional profiling of initial differentiation events in human embryonic stem cells. Biochem Biophys Res Commun 323:453-464.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 453-464
-
-
Calhoun, J.D.1
Rao, R.R.2
Warrenfeltz, S.3
Rekaya, R.4
Dalton, S.5
McDonald, J.6
Stice, S.L.7
-
50
-
-
19944386909
-
Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies
-
Dvash T, Y Mayshar, H Darr, M McElhaney, D Barker, O Yanuka, KJ Kotkow, LL Rubin, N Benvenisty and R Eiges. (2004). Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. Hum Reprod 19:2875-2883.
-
(2004)
Hum Reprod
, vol.19
, pp. 2875-2883
-
-
Dvash, T.1
Mayshar, Y.2
Darr, H.3
McElhaney, M.4
Barker, D.5
Yanuka, O.6
Kotkow, K.J.7
Rubin, L.L.8
Benvenisty, N.9
Eiges, R.10
-
51
-
-
33748884332
-
Expression of leukemia inhibitory factor and its receptors is increased during differentiation of human embryonic stem cells
-
Aghajanova L, H Skottman, AM Stromberg, J Inzunza, R Lahesmaa and O Hovatta. (2006). Expression of leukemia inhibitory factor and its receptors is increased during differentiation of human embryonic stem cells. Fertil Steril 86 Suppl 4:1193-1209.
-
(2006)
Fertil Steril
, vol.86
, Issue.SUPPL. 4
, pp. 1193-1209
-
-
Aghajanova, L.1
Skottman, H.2
Stromberg, A.M.3
Inzunza, J.4
Lahesmaa, R.5
Hovatta, O.6
-
52
-
-
16244385292
-
Antioxidant and cytoprotective responses to redox stress
-
Mathers J, JA Fraser, M McMahon, RD Saunders, JD Hayes and LI McLellan. (2004). Antioxidant and cytoprotective responses to redox stress. Biochem Soc Symp:157-176.
-
(2004)
Biochem Soc Symp
, pp. 157-176
-
-
Mathers, J.1
Fraser, J.A.2
McMahon, M.3
Saunders, R.D.4
Hayes, J.D.5
McLellan, L.I.6
-
53
-
-
1642368362
-
Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: A new therapeutic approach for the treatment of inflammatory diseases
-
Chen XL and C Kunsch. (2004). Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases. Curr Pharm Des 10:879-891.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 879-891
-
-
Chen, X.L.1
Kunsch, C.2
-
54
-
-
14044254798
-
Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation
-
Kobayashi M and M Yamamoto. (2005). Molecular mechanisms activating the Nrf2-Keap1 pathway of antioxidant gene regulation. Antioxid Redox Signal 7:385-394.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 385-394
-
-
Kobayashi, M.1
Yamamoto, M.2
-
55
-
-
14644442994
-
Versican protects cells from oxidative stress-induced apoptosis
-
Wu Y, J Wu, DY Lee, A Yee, L Cao, Y Zhang, C Kiani and BB Yang. (2005). Versican protects cells from oxidative stress-induced apoptosis. Matrix Biol 24:3-13.
-
(2005)
Matrix Biol
, vol.24
, pp. 3-13
-
-
Wu, Y.1
Wu, J.2
Lee, D.Y.3
Yee, A.4
Cao, L.5
Zhang, Y.6
Kiani, C.7
Yang, B.B.8
-
56
-
-
0034912179
-
Lysosomal membrane proteins
-
Winchester BG. (2001). Lysosomal membrane proteins. Eur J Paediatr Neurol 5 Suppl A:11-19.
-
(2001)
Eur J Paediatr Neurol
, vol.5
, Issue.SUPPL. A
, pp. 11-19
-
-
Winchester, B.G.1
-
57
-
-
24044529187
-
Altered status of glutathione and its metabolites in cystinotic cells
-
Levtchenko E, A de Graaf-Hess, M Wilmer, L van den Heuvel, L Monnens and H Blom. (2005). Altered status of glutathione and its metabolites in cystinotic cells. Nephrol Dial Transplant 20:1828-1832.
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 1828-1832
-
-
Levtchenko, E.1
de Graaf-Hess, A.2
Wilmer, M.3
van den Heuvel, L.4
Monnens, L.5
Blom, H.6
-
58
-
-
11244315697
-
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
-
Manalo DJ, A Rowan, T Lavoie, L Natarajan, BD Kelly, SQ Ye, JG Garcia and GL Semenza. (2005). Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood 105:659-669.
-
(2005)
Blood
, vol.105
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.7
Semenza, G.L.8
-
59
-
-
0034255036
-
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
-
Bruick RK. (2000). Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia. Proc Natl Acad Sci USA 97:9082-9087.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 9082-9087
-
-
Bruick, R.K.1
-
60
-
-
0043091971
-
BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF
-
Kothari S, J Cizeau, E McMillan-Ward, SJ Israels, M Bailes, K Ens, LA Kirshenbaum and SB Gibson. (2003). BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF. Oncogene 22:4734-4744.
-
(2003)
Oncogene
, vol.22
, pp. 4734-4744
-
-
Kothari, S.1
Cizeau, J.2
McMillan-Ward, E.3
Israels, S.J.4
Bailes, M.5
Ens, K.6
Kirshenbaum, L.A.7
Gibson, S.B.8
-
61
-
-
0036118562
-
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis
-
Shoshani T, A Faerman, I Mett, E Zelin, T Tenne, S Gorodin, Y Moshel, S Elbaz, A Budanov, A Chajut, H Kalinski, I Kamer, A Rozen, O Mor, E Keshet, D Leshkowitz, P Einat, R Skaliter and E Feinstein. (2002). Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis. Mol Cell Biol 22:2283-2293.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2283-2293
-
-
Shoshani, T.1
Faerman, A.2
Mett, I.3
Zelin, E.4
Tenne, T.5
Gorodin, S.6
Moshel, Y.7
Elbaz, S.8
Budanov, A.9
Chajut, A.10
Kalinski, H.11
Kamer, I.12
Rozen, A.13
Mor, O.14
Keshet, E.15
Leshkowitz, D.16
Einat, P.17
Skaliter, R.18
Feinstein, E.19
-
62
-
-
0027971167
-
Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia
-
Graven KK, RF Troxler, H Kornfeld, MV Panchenko and HW Farber. (1994). Regulation of endothelial cell glyceraldehyde-3-phosphate dehydrogenase expression by hypoxia. J Biol Chem 269:24446-24453.
-
(1994)
J Biol Chem
, vol.269
, pp. 24446-24453
-
-
Graven, K.K.1
Troxler, R.F.2
Kornfeld, H.3
Panchenko, M.V.4
Farber, H.W.5
-
63
-
-
33645766052
-
Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities
-
Forsyth NR, A Musio, P Vezzoni, AH Simpson, BS Noble and J McWhir. (2006). Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities. Cloning Stem Cells 8:16-23.
-
(2006)
Cloning Stem Cells
, vol.8
, pp. 16-23
-
-
Forsyth, N.R.1
Musio, A.2
Vezzoni, P.3
Simpson, A.H.4
Noble, B.S.5
McWhir, J.6
-
64
-
-
36249020427
-
Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan
-
Fehrer C, R Brunauer, G Laschober, H Unterluggauer, S Reitinger, F Kloss, C Gully, R Gassner and G Lepperdinger. (2007). Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan. Aging Cell 6:745-757.
-
(2007)
Aging Cell
, vol.6
, pp. 745-757
-
-
Fehrer, C.1
Brunauer, R.2
Laschober, G.3
Unterluggauer, H.4
Reitinger, S.5
Kloss, F.6
Gully, C.7
Gassner, R.8
Lepperdinger, G.9
-
65
-
-
33646016858
-
Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells
-
D'Ippolito G, S Diabira, GA Howard, BA Roos and PC Schiller. (2006). Low oxygen tension inhibits osteogenic differentiation and enhances stemness of human MIAMI cells. Bone 39:513-522.
-
(2006)
Bone
, vol.39
, pp. 513-522
-
-
D'Ippolito, G.1
Diabira, S.2
Howard, G.A.3
Roos, B.A.4
Schiller, P.C.5
-
66
-
-
33745606483
-
Establishment of new mouse embryonic stem cell lines is improved by physiological glucose and oxygen
-
Wang F, S Thirumangalathu and MR Loeken. (2006). Establishment of new mouse embryonic stem cell lines is improved by physiological glucose and oxygen. Cloning Stem Cells 8:108-116.
-
(2006)
Cloning Stem Cells
, vol.8
, pp. 108-116
-
-
Wang, F.1
Thirumangalathu, S.2
Loeken, M.R.3
-
67
-
-
0034028901
-
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
-
Niwa H, J Miyazaki and AG Smith. (2000). Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 24:372-376.
-
(2000)
Nat Genet
, vol.24
, pp. 372-376
-
-
Niwa, H.1
Miyazaki, J.2
Smith, A.G.3
-
68
-
-
0038348295
-
Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures
-
Shimozaki K, K Nakashima, H Niwa and T Taga. (2003). Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures. Development 130:2505-2512.
-
(2003)
Development
, vol.130
, pp. 2505-2512
-
-
Shimozaki, K.1
Nakashima, K.2
Niwa, H.3
Taga, T.4
-
69
-
-
1442311693
-
Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
-
Hay DC, L Sutherland, J Clark and T Burdon. (2004). Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 22:225-235.
-
(2004)
Stem Cells
, vol.22
, pp. 225-235
-
-
Hay, D.C.1
Sutherland, L.2
Clark, J.3
Burdon, T.4
-
70
-
-
0034719512
-
Nodal signalling in vertebrate development
-
Schier AF and MM Shen. (2000). Nodal signalling in vertebrate development. Nature 403:385-389.
-
(2000)
Nature
, vol.403
, pp. 385-389
-
-
Schier, A.F.1
Shen, M.M.2
-
71
-
-
0036240683
-
Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion
-
Sakuma R, Y Ohnishi Yi, C Meno, H Fujii, H Juan, J Takeuchi, T Ogura, E Li, K Miyazono and H Hamada. (2002). Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion. Genes Cells 7:401-412.
-
(2002)
Genes Cells
, vol.7
, pp. 401-412
-
-
Sakuma, R.1
Ohnishi Yi, Y.2
Meno, C.3
Fujii, H.4
Juan, H.5
Takeuchi, J.6
Ogura, T.7
Li, E.8
Miyazono, K.9
Hamada, H.10
-
72
-
-
0345255908
-
Nodal signaling in vertebrate development
-
Schier AF. (2003). Nodal signaling in vertebrate development. Annu Rev Cell Dev Biol 19:589-621.
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 589-621
-
-
Schier, A.F.1
-
73
-
-
0345491599
-
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
-
Hu CJ, LY Wang, LA Chodosh, B Keith and MC Simon. (2003). Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol 23:9361-9374.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 9361-9374
-
-
Hu, C.J.1
Wang, L.Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
74
-
-
0033233243
-
Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1
-
Semenza GL. (1999). Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Annu Rev Cell Dev Biol 15:551-578.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 551-578
-
-
Semenza, G.L.1
-
75
-
-
0141988698
-
Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
-
Sowter HM, RR Raval, JW Moore, PJ Ratcliffe and AL Harris. (2003). Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res 63:6130-6134.
-
(2003)
Cancer Res
, vol.63
, pp. 6130-6134
-
-
Sowter, H.M.1
Raval, R.R.2
Moore, J.W.3
Ratcliffe, P.J.4
Harris, A.L.5
-
76
-
-
17144416530
-
Differential gene up-regulation by hypoxia-inducible factor-1α and hypoxia-inducible factor-2α in HEK293T Cells
-
Wang V, DA Davis, M Haque, LE Huang and R Yarchoan. (2005). Differential gene up-regulation by hypoxia-inducible factor-1α and hypoxia-inducible factor-2α in HEK293T Cells. Cancer Res 65:3299-3306.
-
(2005)
Cancer Res
, vol.65
, pp. 3299-3306
-
-
Wang, V.1
Davis, D.A.2
Haque, M.3
Huang, L.E.4
Yarchoan, R.5
-
77
-
-
33750630119
-
Recruitment of HIF-1[alpha] and HIF-2[alpha] to common target genes is differentially regulated in neuroblastoma: HIF-2[alpha] promotes an aggressive phenotype
-
Holmquist-Mengelbier L, E Fredlund, T Lofstedt, R Noguera, S Navarro, H Nilsson, A Pietras, J Vallon-Christersson, A Borg, K Gradin, L Poellinger and S Pahlman. (2006). Recruitment of HIF-1[alpha] and HIF-2[alpha] to common target genes is differentially regulated in neuroblastoma: HIF-2[alpha] promotes an aggressive phenotype. Cancer Cell 10:413-423.
-
(2006)
Cancer Cell
, vol.10
, pp. 413-423
-
-
Holmquist-Mengelbier, L.1
Fredlund, E.2
Lofstedt, T.3
Noguera, R.4
Navarro, S.5
Nilsson, H.6
Pietras, A.7
Vallon-Christersson, J.8
Borg, A.9
Gradin, K.10
Poellinger, L.11
Pahlman, S.12
-
78
-
-
34247527730
-
Hypoxia-Inducible Factors, Stem Cells, and Cancer
-
Keith B and MC Simon. (2007). Hypoxia-Inducible Factors, Stem Cells, and Cancer. Cell 129:465-472.
-
(2007)
Cell
, vol.129
, pp. 465-472
-
-
Keith, B.1
Simon, M.C.2
-
79
-
-
4143078131
-
The PAI-1 gene as a direct target of endothelial PAS domain protein-1 in adenocarcinoma A549 cells
-
Sato M, T Tanaka, K Maemura, T Uchiyama, H Sato, T Maeno, T Suga, T Iso, Y Ohyama, M Arai, J Tamura, H Sakamoto, R Nagai and M Kurabayashi. (2004). The PAI-1 gene as a direct target of endothelial PAS domain protein-1 in adenocarcinoma A549 cells. Am J Respir Cell Mol Biol 31:209-215.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 209-215
-
-
Sato, M.1
Tanaka, T.2
Maemura, K.3
Uchiyama, T.4
Sato, H.5
Maeno, T.6
Suga, T.7
Iso, T.8
Ohyama, Y.9
Arai, M.10
Tamura, J.11
Sakamoto, H.12
Nagai, R.13
Kurabayashi, M.14
|