-
1
-
-
79955830308
-
Protective role of heat shock proteins in Parkinson's disease
-
CrossRef Medline
-
Aridon P, Geraci F, Turturici G, D'Amelio M, Savettieri G, Sconzo G (2011) Protective role of heat shock proteins in Parkinson's disease. Neurodegener Dis 8: 155-168. CrossRef Medline
-
(2011)
Neurodegener Dis
, vol.8
, pp. 155-168
-
-
Aridon, P.1
Geraci, F.2
Turturici, G.3
D'Amelio, M.4
Savettieri, G.5
Sconzo, G.6
-
2
-
-
0036852712
-
Pharmacological prevention of parkinson disease in Drosophila
-
CrossRef Medline
-
Auluck PK, Bonini NM (2002) Pharmacological prevention of parkinson disease in Drosophila. Nat Med 8: 1185-1186. CrossRef Medline
-
(2002)
Nat Med
, vol.8
, pp. 1185-1186
-
-
Auluck, P.K.1
Bonini, N.M.2
-
3
-
-
79551517312
-
Selective toxicity by HDAC3 in neurons: Regulation by Akt and GSK3beta
-
CrossRef Medline
-
Bardai FH, D'Mello SR (2011) Selective toxicity by HDAC3 in neurons: regulation by Akt and GSK3beta. J Neurosci 31: 1746-1751. CrossRef Medline
-
(2011)
J Neurosci
, vol.31
, pp. 1746-1751
-
-
Bardai, F.H.1
D'Mello, S.R.2
-
4
-
-
84867431257
-
Histone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death
-
CrossRef Medline
-
Bardai FH, Price V, Zaayman M, Wang L, D'Mello SR (2012) Histone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death. J Biol Chem 287: 35444-35453. CrossRef Medline
-
(2012)
J Biol Chem
, vol.287
, pp. 35444-35453
-
-
Bardai, F.H.1
Price, V.2
Zaayman, M.3
Wang, L.4
D'Mello, S.R.5
-
5
-
-
84880422675
-
Disassociation of histone deacetylase-3 from normal huntingtin underlies mutant huntingtin neurotoxicity
-
CrossRef Medline
-
Bardai FH, Verma P, Smith C, Rawat V, Wang L, D'Mello SR (2013) Disassociation of histone deacetylase-3 from normal huntingtin underlies mutant huntingtin neurotoxicity. J Neurosci 33: 11833-11838. CrossRef Medline
-
(2013)
J Neurosci
, vol.33
, pp. 11833-11838
-
-
Bardai, F.H.1
Verma, P.2
Smith, C.3
Rawat, V.4
Wang, L.5
D'Mello, S.R.6
-
6
-
-
33749989045
-
Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis
-
CrossRef Medline
-
Batulan Z, Taylor DM, Aarons RJ, Minotti S, Doroudchi MM, Nalbantoglu J, Durham HD (2006) Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis. Neurobiol Dis 24: 213-225. CrossRef Medline
-
(2006)
Neurobiol Dis
, vol.24
, pp. 213-225
-
-
Batulan, Z.1
Taylor, D.M.2
Aarons, R.J.3
Minotti, S.4
Doroudchi, M.M.5
Nalbantoglu, J.6
Durham, H.D.7
-
7
-
-
13244287963
-
The transcription factor NFAT3 mediates neuronal survival
-
Medline
-
Benedito AB, Lehtinen M, Massol R, Lopes UG, Kirchhausen T, Rao A, Bonni A (2005) The transcription factor NFAT3 mediates neuronal survival. J Biol Chem 280: 2818-2825. Medline
-
(2005)
J Biol Chem
, vol.280
, pp. 2818-2825
-
-
Benedito, A.B.1
Lehtinen, M.2
Massol, R.3
Lopes, U.G.4
Kirchhausen, T.5
Rao, A.6
Bonni, A.7
-
8
-
-
77957278382
-
Regulation of the members of the mammalian heat shock factor family
-
CrossRef Medline
-
Björk JK, Sistonen L (2010) Regulation of the members of the mammalian heat shock factor family. FEBS J 277: 4126-4139. CrossRef Medline
-
(2010)
FEBS J
, vol.277
, pp. 4126-4139
-
-
Björk, J.K.1
Sistonen, L.2
-
9
-
-
0037059040
-
Chaperoning brain degeneration
-
Medline
-
Bonini NM (2002) Chaperoning brain degeneration. Proc Natl Acad Sci USA 99: 16407-16411. Medline
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16407-16411
-
-
Bonini, N.M.1
-
10
-
-
0031873788
-
Decreased expression of the metabotropic glutamate receptor-4 gene is associated with neuronal apoptosis
-
CrossRef Medline
-
Borodezt K, D'Mello SR (1998) Decreased expression of the metabotropic glutamate receptor-4 gene is associated with neuronal apoptosis. J Neurosci Res 53: 531-541. CrossRef Medline
-
(1998)
J Neurosci Res
, vol.53
, pp. 531-541
-
-
Borodezt, K.1
D'Mello, S.R.2
-
11
-
-
33846471587
-
Activation of PI3-K/Akt pathway for thermal preconditioning to protect cultured cerebellar granule neurons against low potassiuminduced apoptosis
-
CrossRef Medline
-
Cao L, Cao DX, Su XW, Chen LJ, Liu AL, Jian WJ, Wu YP, Qiu PX, Yan GM (2007) Activation of PI3-K/Akt pathway for thermal preconditioning to protect cultured cerebellar granule neurons against low potassiuminduced apoptosis. Acta Pharmacol Sin 28: 173-179. CrossRef Medline
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 173-179
-
-
Cao, L.1
Cao, D.X.2
Su, X.W.3
Chen, L.J.4
Liu, A.L.5
Jian, W.J.6
Wu, Y.P.7
Qiu, P.X.8
Yan, G.M.9
-
12
-
-
1842809934
-
Thermal preconditioning protected cerebellar granule neurons of rats by modulating HSP70 expression
-
Medline
-
Chen LJ, Su XW, Qiu PX, Huang YJ, Yan GM (2004) Thermal preconditioning protected cerebellar granule neurons of rats by modulating HSP70 expression. Acta Pharmacol Sin 25: 458-461. Medline
-
(2004)
Acta Pharmacol Sin
, vol.25
, pp. 458-461
-
-
Chen, L.J.1
Su, X.W.2
Qiu, P.X.3
Huang, Y.J.4
Yan, G.M.5
-
13
-
-
84860357492
-
Transducin-like enhancer of split-1 (TLE1) combines with forkhead box protein G1 (FoxG1) to promote neuronal survival
-
CrossRef Medline
-
Dastidar SG, Narayanan S, Stifani S, D'Mello SR (2012) Transducin-like enhancer of split-1 (TLE1) combines with forkhead box protein G1 (FoxG1) to promote neuronal survival. J Biol Chem 287: 14749-14759. CrossRef Medline
-
(2012)
J Biol Chem
, vol.287
, pp. 14749-14759
-
-
Dastidar, S.G.1
Narayanan, S.2
Stifani, S.3
D'Mello, S.R.4
-
14
-
-
0242690439
-
Quantitative analysis of binding of transcription factor complex to biotinylated DNA probe by a streptavidin-agarose pulldown assay
-
CrossRef Medline
-
Deng WG, Zhu Y, Montero A, Wu KK (2003) Quantitative analysis of binding of transcription factor complex to biotinylated DNA probe by a streptavidin-agarose pulldown assay. Anal Biochem 323: 12-18. CrossRef Medline
-
(2003)
Anal Biochem
, vol.323
, pp. 12-18
-
-
Deng, W.G.1
Zhu, Y.2
Montero, A.3
Wu, K.K.4
-
15
-
-
0027483920
-
Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP
-
CrossRef Medline
-
D'Mello SR, Galli C, Ciotti T, Calissano P (1993) Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP. Proc Natl Acad Sci U S A 90: 10989-10993. CrossRef Medline
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 10989-10993
-
-
D'Mello, S.R.1
Galli, C.2
Ciotti, T.3
Calissano, P.4
-
16
-
-
0031931412
-
Intramolecular repression of mouse heat shock factor 1
-
Medline
-
Farkas T, Kutskova YA, Zimarino V (1998) Intramolecular repression of mouse heat shock factor 1. Mol Cell Biol 18: 906-918. Medline
-
(1998)
Mol Cell Biol
, vol.18
, pp. 906-918
-
-
Farkas, T.1
Kutskova, Y.A.2
Zimarino, V.3
-
17
-
-
54449101793
-
Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones
-
CrossRef Medline
-
Fujikake N, Nagai Y, Popiel HA, Okamoto Y, Yamaguchi M, Toda T (2008) Heat shock transcription factor 1-activating compounds suppress polyglutamine-induced neurodegeneration through induction of multiple molecular chaperones. J Biol Chem 283: 26188-26197. CrossRef Medline
-
(2008)
J Biol Chem
, vol.283
, pp. 26188-26197
-
-
Fujikake, N.1
Nagai, Y.2
Popiel, H.A.3
Okamoto, Y.4
Yamaguchi, M.5
Toda, T.6
-
18
-
-
77957252262
-
The heat shock factor family and adaptation to proteotoxic stress
-
CrossRef Medline
-
Fujimoto M, Nakai A (2010) The heat shock factor family and adaptation to proteotoxic stress. FEBS J 277: 4112-4125. CrossRef Medline
-
(2010)
FEBS J
, vol.277
, pp. 4112-4125
-
-
Fujimoto, M.1
Nakai, A.2
-
19
-
-
27144524290
-
Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
-
CrossRef Medline
-
Fujimoto M, Takaki E, Hayashi T, Kitaura Y, Tanaka Y, Inouye S, Nakai A (2005) Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models. J Biol Chem 280: 34908-34916. CrossRef Medline
-
(2005)
J Biol Chem
, vol.280
, pp. 34908-34916
-
-
Fujimoto, M.1
Takaki, E.2
Hayashi, T.3
Kitaura, Y.4
Tanaka, Y.5
Inouye, S.6
Nakai, A.7
-
20
-
-
75649144450
-
A novel mouse HSF3 has the potential to activate nonclassical heat-shock genes during heat shock
-
CrossRef Medline
-
Fujimoto M, Hayashida N, Katoh T, Oshima K, Shinkawa T, Prakasam R, Tan K, Inouye S, Takii R, Nakai A (2010) A novel mouse HSF3 has the potential to activate nonclassical heat-shock genes during heat shock. Mol Biol Cell 21: 106-116. CrossRef Medline
-
(2010)
Mol Biol Cell
, vol.21
, pp. 106-116
-
-
Fujimoto, M.1
Hayashida, N.2
Katoh, T.3
Oshima, K.4
Shinkawa, T.5
Prakasam, R.6
Tan, K.7
Inouye, S.8
Takii, R.9
Nakai, A.10
-
21
-
-
0028924891
-
Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: The involvement of intracellular calcium and RNA synthesis
-
Medline
-
Galli C, Meucci O, Scorziello A, Werge TM, Calissano P, Schettini G (1995) Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis. J Neurosci 15: 1172-1179. Medline
-
(1995)
J Neurosci
, vol.15
, pp. 1172-1179
-
-
Galli, C.1
Meucci, O.2
Scorziello, A.3
Werge, T.M.4
Calissano, P.5
Schettini, G.6
-
22
-
-
2942598422
-
Genome-wide analysis of the biology of stress responses through heat shock transcription factor
-
CrossRef Medline
-
Hahn JS, Hu Z, Thiele DJ, Iyer VR (2004) Genome-wide analysis of the biology of stress responses through heat shock transcription factor. Mol Cell Biol 24: 5249-5256. CrossRef Medline
-
(2004)
Mol Cell Biol
, vol.24
, pp. 5249-5256
-
-
Hahn, J.S.1
Hu, Z.2
Thiele, D.J.3
Iyer, V.R.4
-
23
-
-
78049233238
-
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway
-
CrossRef Medline
-
Haskew-Layton RE, Payappilly JB, Smirnova NA, Ma TC, Chan KK, Murphy TH, Guo H, Langley B, Sultana R, Butterfield DA, Santagata S, Alldred MJ, Gazaryan IG, Bell GW, Ginsberg SD, Ratan RR (2010) Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway. Proc Natl Acad Sci U S A 107: 17385-17390. CrossRef Medline
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 17385-17390
-
-
Haskew-Layton, R.E.1
Payappilly, J.B.2
Smirnova, N.A.3
Ma, T.C.4
Chan, K.K.5
Murphy, T.H.6
Guo, H.7
Langley, B.8
Sultana, R.9
Butterfield, D.A.10
Santagata, S.11
Alldred, M.J.12
Gazaryan, I.G.13
Bell, G.W.14
Ginsberg, S.D.15
Ratan, R.R.16
-
24
-
-
33750212109
-
A novel HSF1-mediated death pathway that is suppressed by heat shock proteins
-
CrossRef Medline
-
Hayashida N, Inouye S, Fujimoto M, Tanaka Y, Izu H, Takaki E, Ichikawa H, Rho J, Nakai A (2006) A novel HSF1-mediated death pathway that is suppressed by heat shock proteins. EMBO J 25: 4773-4783. CrossRef Medline
-
(2006)
EMBO J
, vol.25
, pp. 4773-4783
-
-
Hayashida, N.1
Inouye, S.2
Fujimoto, M.3
Tanaka, Y.4
Izu, H.5
Takaki, E.6
Ichikawa, H.7
Rho, J.8
Nakai, A.9
-
25
-
-
77958449033
-
Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT
-
CrossRef Medline
-
Hayashida N, Fujimoto M, Tan K, Prakasam R, Shinkawa T, Li L, Ichikawa H, Takii R, Nakai A (2010) Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT. EMBO J 29: 3459-3469. CrossRef Medline
-
(2010)
EMBO J
, vol.29
, pp. 3459-3469
-
-
Hayashida, N.1
Fujimoto, M.2
Tan, K.3
Prakasam, R.4
Shinkawa, T.5
Li, L.6
Ichikawa, H.7
Takii, R.8
Nakai, A.9
-
26
-
-
0042818001
-
Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress
-
CrossRef Medline
-
He H, Soncin F, Grammatikakis N, Li Y, Siganou A, Gong J, Brown SA, Kingston RE, Calderwood SK (2003) Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress. J Biol Chem 278: 35465-35475. CrossRef Medline
-
(2003)
J Biol Chem
, vol.278
, pp. 35465-35475
-
-
He, H.1
Soncin, F.2
Grammatikakis, N.3
Li, Y.4
Siganou, A.5
Gong, J.6
Brown, S.A.7
Kingston, R.E.8
Calderwood, S.K.9
-
27
-
-
17844386323
-
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1
-
CrossRef Medline
-
Holmberg CI, Hietakangas V, Mikhailov A, Rantanen JO, Kallio M, Meinander A, Hellman J, Morrice N, MacKintosh C, Morimoto RI, Eriksson JE, Sistonen L (2001) Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1. EMBO J 20: 3800-3810. CrossRef Medline
-
(2001)
EMBO J
, vol.20
, pp. 3800-3810
-
-
Holmberg, C.I.1
Hietakangas, V.2
Mikhailov, A.3
Rantanen, J.O.4
Kallio, M.5
Meinander, A.6
Hellman, J.7
Morrice, N.8
McKintosh, C.9
Morimoto, R.I.10
Eriksson, J.E.11
Sistonen, L.12
-
28
-
-
34547420555
-
Demyelination, astrogliosis, and accumulation of ubiquitinated proteins, hallmarks of CNS disease in hsf1-deficient mice
-
CrossRef Medline
-
Homma S, Jin X, Wang G, Tu N, Min J, Yanasak N, Mivechi NF (2007) Demyelination, astrogliosis, and accumulation of ubiquitinated proteins, hallmarks of CNS disease in hsf1-deficient mice. J Neurosci 27: 7974-7986. CrossRef Medline
-
(2007)
J Neurosci
, vol.27
, pp. 7974-7986
-
-
Homma, S.1
Jin, X.2
Wang, G.3
Tu, N.4
Min, J.5
Yanasak, N.6
Mivechi, N.F.7
-
29
-
-
36349036470
-
Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor
-
CrossRef Medline
-
Inouye S, Fujimoto M, Nakamura T, Takaki E, Hayashida N, Hai T, Nakai A (2007) Heat shock transcription factor 1 opens chromatin structure of interleukin-6 promoter to facilitate binding of an activator or a repressor. J Biol Chem 282: 33210-33217. CrossRef Medline
-
(2007)
J Biol Chem
, vol.282
, pp. 33210-33217
-
-
Inouye, S.1
Fujimoto, M.2
Nakamura, T.3
Takaki, E.4
Hayashida, N.5
Hai, T.6
Nakai, A.7
-
30
-
-
15844405223
-
Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells
-
CrossRef Medline
-
Jain MK, Fujita KP, Hsieh CM, Endege WO, Sibinga NE, Yet SF, Kashiki S, Lee WS, Perrella MA, Haber E, Lee ME (1996) Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells. J Biol Chem 271: 10194-10199. CrossRef Medline
-
(1996)
J Biol Chem
, vol.271
, pp. 10194-10199
-
-
Jain, M.K.1
Fujita, K.P.2
Hsieh, C.M.3
Endege, W.O.4
Sibinga, N.E.5
Yet, S.F.6
Kashiki, S.7
Lee, W.S.8
Perrella, M.A.9
Haber, E.10
Lee, M.E.11
-
31
-
-
0032538947
-
Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system
-
CrossRef Medline
-
Jain MK, Kashiki S, Hsieh CM, Layne MD, Yet SF, Sibinga NE, Chin MT, Feinberg MW, Woo I, Maas RL, Haber E, Lee ME (1998) Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system. Circ Res 83: 980-985. CrossRef Medline
-
(1998)
Circ Res
, vol.83
, pp. 980-985
-
-
Jain, M.K.1
Kashiki, S.2
Hsieh, C.M.3
Layne, M.D.4
Yet, S.F.5
Sibinga, N.E.6
Chin, M.T.7
Feinberg, M.W.8
Woo, I.9
Maas, R.L.10
Haber, E.11
Lee, M.E.12
-
32
-
-
84855563516
-
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
-
CrossRef Medline
-
Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR, Yates JR 3rd, Bordone L, Guarente L, Krainc D (2012) Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nat Med 18: 159-165. CrossRef Medline
-
(2012)
Nat Med
, vol.18
, pp. 159-165
-
-
Jeong, H.1
Cohen, D.E.2
Cui, L.3
Supinski, A.4
Savas, J.N.5
Mazzulli, J.R.6
Yates III, J.R.7
Bordone, L.8
Guarente, L.9
Krainc, D.10
-
33
-
-
84855544817
-
Neuroprotective role of Sirt1 in mammalian models of huntington's disease through activation of multiple Sirt1 targets
-
CrossRef Medline
-
Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W (2011) Neuroprotective role of Sirt1 in mammalian models of huntington's disease through activation of multiple Sirt1 targets. Nat Med 18: 153-158. CrossRef Medline
-
(2011)
Nat Med
, vol.18
, pp. 153-158
-
-
Jiang, M.1
Wang, J.2
Fu, J.3
Du, L.4
Jeong, H.5
West, T.6
Xiang, L.7
Peng, Q.8
Hou, Z.9
Cai, H.10
Seredenina, T.11
Arbez, N.12
Zhu, S.13
Sommers, K.14
Qian, J.15
Zhang, J.16
Mori, S.17
Yang, X.W.18
Tamashiro, K.L.19
Aja, S.20
Moran, T.H.21
Luthi-Carter, R.22
Martin, B.23
Maudsley, S.24
Mattson, M.P.25
Cichewicz, R.H.26
Ross, C.A.27
Holtzman, D.M.28
Krainc, D.29
Duan, W.30
more..
-
34
-
-
18444415138
-
Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice
-
CrossRef Medline
-
Kallio M, Chang Y, Manuel M, Alastalo TP, Rallu M, Gitton Y, Pirkkala L, Loones MT, Paslaru L, Larney S, Hiard S, Morange M, Sistonen L, Mezger V (2002) Brain abnormalities, defective meiotic chromosome synapsis and female subfertility in HSF2 null mice. EMBO J 21: 2591-2601. CrossRef Medline
-
(2002)
EMBO J
, vol.21
, pp. 2591-2601
-
-
Kallio, M.1
Chang, Y.2
Manuel, M.3
Alastalo, T.P.4
Rallu, M.5
Gitton, Y.6
Pirkkala, L.7
Loones, M.T.8
Paslaru, L.9
Larney, S.10
Hiard, S.11
Morange, M.12
Sistonen, L.13
Mezger, V.14
-
35
-
-
82455219091
-
Peptide switch is essential for Sirt1 deacetylase activity
-
CrossRef Medline
-
Kang H, Suh JY, Jung YS, Jung JW, Kim MK, Chung JH (2011) Peptide switch is essential for Sirt1 deacetylase activity. Mol Cell 44: 203-213. CrossRef Medline
-
(2011)
Mol Cell
, vol.44
, pp. 203-213
-
-
Kang, H.1
Suh, J.Y.2
Jung, Y.S.3
Jung, J.W.4
Kim, M.K.5
Chung, J.H.6
-
36
-
-
28044469532
-
Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease
-
CrossRef Medline
-
Katsuno M, Sang C, Adachi H, Minamiyama M, Waza M, Tanaka F, Doyu M, Sobue G (2005) Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease. Proc Natl Acad Sci U S A 102: 16801-16806. CrossRef Medline
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 16801-16806
-
-
Katsuno, M.1
Sang, C.2
Adachi, H.3
Minamiyama, M.4
Waza, M.5
Tanaka, F.6
Doyu, M.7
Sobue, G.8
-
37
-
-
1942486792
-
Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice
-
CrossRef Medline
-
Kieran D, Kalmar B, Dick JR, Riddoch-Contreras J, Burnstock G, Greensmith L (2004) Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med 10: 402-405. CrossRef Medline
-
(2004)
Nat Med
, vol.10
, pp. 402-405
-
-
Kieran, D.1
Kalmar, B.2
Dick, J.R.3
Riddoch-Contreras, J.4
Burnstock, G.5
Greensmith, L.6
-
38
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for alzheimer's disease and amyotrophic lateral sclerosis
-
CrossRef Medline
-
Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH (2007) SIRT1 deacetylase protects against neurodegeneration in models for alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 26: 3169-3179. CrossRef Medline
-
(2007)
EMBO J
, vol.26
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
Puigserver, P.11
Sinclair, D.A.12
Tsai, L.H.13
-
39
-
-
84885415875
-
The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters
-
CrossRef Medline
-
Kim JA, Kim Y, Kwon BM, Han DC (2013) The natural compound cantharidin induces cancer cell death through inhibition of heat shock protein 70 (HSP70) and bcl-2-associated athanogene domain 3 (BAG3) expression by blocking heat shock factor 1 (HSF1) binding to promoters. J Biol Chem 288: 28713-28726. CrossRef Medline
-
(2013)
J Biol Chem
, vol.288
, pp. 28713-28726
-
-
Kim, J.A.1
Kim, Y.2
Kwon, B.M.3
Han, D.C.4
-
40
-
-
38749088678
-
DBC1 is a negative regulator of SIRT1
-
CrossRef Medline
-
Kim JE, Chen J, Lou Z (2008) DBC1 is a negative regulator of SIRT1. Nature 451: 583-586. CrossRef Medline
-
(2008)
Nature
, vol.451
, pp. 583-586
-
-
Kim, J.E.1
Chen, J.2
Lou, Z.3
-
41
-
-
73049085606
-
cJun modulates ggamma-globin gene expression via an upstream cAMP response element
-
CrossRef Medline
-
Kodeboyina S, Balamurugan P, Liu L, Pace BS (2010) cJun modulates ggamma-globin gene expression via an upstream cAMP response element. Blood Cells Mol Dis 44: 7-15. CrossRef Medline
-
(2010)
Blood Cells Mol Dis
, vol.44
, pp. 7-15
-
-
Kodeboyina, S.1
Balamurugan, P.2
Liu, L.3
Pace, B.S.4
-
42
-
-
84879154600
-
Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration
-
CrossRef Medline
-
Kondo N, Katsuno M, Adachi H, Minamiyama M, Doi H, Matsumoto S, Miyazaki Y, Iida M, Tohnai G, Nakatsuji H, Ishigaki S, Fujioka Y, Watanabe H, Tanaka F, Nakai A, Sobue G (2013) Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration. Nat Commun 4: 1405. CrossRef Medline
-
(2013)
Nat Commun
, vol.4
, pp. 1405
-
-
Kondo, N.1
Katsuno, M.2
Adachi, H.3
Minamiyama, M.4
Doi, H.5
Matsumoto, S.6
Miyazaki, Y.7
Iida, M.8
Tohnai, G.9
Nakatsuji, H.10
Ishigaki, S.11
Fujioka, Y.12
Watanabe, H.13
Tanaka, F.14
Nakai, A.15
Sobue, G.16
-
43
-
-
0035112978
-
NF-κB is involved in the survival of cerebellar granule neurons: Association of Iκβ phosphorylation with cell survival
-
CrossRef Medline
-
Koulich E, Nguyen T, Johnson K, Giardina C, D'mello S (2001) NF-κB is involved in the survival of cerebellar granule neurons: association of Iκβ phosphorylation with cell survival. J Neurochem 76: 1188-1198. CrossRef Medline
-
(2001)
J Neurochem
, vol.76
, pp. 1188-1198
-
-
Koulich, E.1
Nguyen, T.2
Johnson, K.3
Giardina, C.4
D'mello, S.5
-
44
-
-
33646133424
-
Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans
-
CrossRef Medline
-
Kraemer BC, Burgess JK, Chen JH, Thomas JH, Schellenberg GD (2006) Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans. Hum Mol Genet 15: 1483-1496. CrossRef Medline
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1483-1496
-
-
Kraemer, B.C.1
Burgess, J.K.2
Chen, J.H.3
Thomas, J.H.4
Schellenberg, G.D.5
-
45
-
-
38149116286
-
Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21 (waf1/ cip1) in cell cycle-independent neuroprotection
-
CrossRef Medline
-
Langley B, D'Annibale MA, Suh K, Ayoub I, Tolhurst A, Bastan B, Yang L, Ko B, Fisher M, Cho S, Beal MF, Ratan RR (2008) Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21 (waf1/ cip1) in cell cycle-independent neuroprotection. J Neurosci 28: 163-176. CrossRef Medline
-
(2008)
J Neurosci
, vol.28
, pp. 163-176
-
-
Langley, B.1
D'Annibale, M.A.2
Suh, K.3
Ayoub, I.4
Tolhurst, A.5
Bastan, B.6
Yang, L.7
Ko, B.8
Fisher, M.9
Cho, S.10
Beal, M.F.11
Ratan, R.R.12
-
46
-
-
77953175438
-
Dominant-positive HSF1 decreases alpha-synuclein level and alphasynuclein-induced toxicity
-
CrossRef Medline
-
Liangliang X, Yonghui H, Shunmei E, Shoufang G, Wei Z, Jiangying Z (2010) Dominant-positive HSF1 decreases alpha-synuclein level and alphasynuclein-induced toxicity. Mol Biol Rep 37: 1875-1881. CrossRef Medline
-
(2010)
Mol Biol Rep
, vol.37
, pp. 1875-1881
-
-
Liangliang, X.1
Yonghui, H.2
Shunmei, E.3
Shoufang, G.4
Wei, Z.5
Jiangying, Z.6
-
47
-
-
0022555843
-
The heat-shock response
-
CrossRef Medline
-
Lindquist S (1986) The heat-shock response. Annu Rev Biochem 55: 1151-1191. CrossRef Medline
-
(1986)
Annu Rev Biochem
, vol.55
, pp. 1151-1191
-
-
Lindquist, S.1
-
48
-
-
0026328490
-
The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity
-
CrossRef Medline
-
Lowenstein DH, Chan PH, Miles MF (1991) The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity. Neuron 7: 1053-1060. CrossRef Medline
-
(1991)
Neuron
, vol.7
, pp. 1053-1060
-
-
Lowenstein, D.H.1
Chan, P.H.2
Miles, M.F.3
-
49
-
-
44449116745
-
Two distinct disulfide bonds formed in human heat shock transcription factor 1 act in opposition to regulate its DNA binding activity
-
CrossRef Medline
-
Lu M, Kim HE, Li CR, Kim S, Kwak IJ, Lee YJ, Kim SS, Moon JY, Kim CH, Kim DK, Kang HS, Park JS (2008) Two distinct disulfide bonds formed in human heat shock transcription factor 1 act in opposition to regulate its DNA binding activity. Biochemistry 47: 6007-6015. CrossRef Medline
-
(2008)
Biochemistry
, vol.47
, pp. 6007-6015
-
-
Lu, M.1
Kim, H.E.2
Li, C.R.3
Kim, S.4
Kwak, I.J.5
Lee, Y.J.6
Kim, S.S.7
Moon, J.Y.8
Kim, C.H.9
Kim, D.K.10
Kang, H.S.11
Park, J.S.12
-
50
-
-
66149138815
-
Aromatic-participant interactions are essential for disulfide-bond-based trimerization in human heat shock transcription factor 1
-
CrossRef Medline
-
Lu M, Lee YJ, Park SM, Kang HS, Kang SW, Kim S, Park JS (2009) Aromatic-participant interactions are essential for disulfide-bond-based trimerization in human heat shock transcription factor 1. Biochemistry 48: 3795-3797. CrossRef Medline
-
(2009)
Biochemistry
, vol.48
, pp. 3795-3797
-
-
Lu, M.1
Lee, Y.J.2
Park, S.M.3
Kang, H.S.4
Kang, S.W.5
Kim, S.6
Park, J.S.7
-
51
-
-
77953012604
-
Heat shock protein 90 in neurodegenerative diseases
-
1326-5-24. CrossRef Medline
-
Luo W, Sun W, Taldone T, Rodina A, Chiosis G (2010) Heat shock protein 90 in neurodegenerative diseases. Mol Neurodegener 5: 24-1326-5-24. CrossRef Medline
-
(2010)
Mol Neurodegener
, vol.5
, pp. 24
-
-
Luo, W.1
Sun, W.2
Taldone, T.3
Rodina, A.4
Chiosis, G.5
-
52
-
-
37549072585
-
Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells
-
CrossRef Medline
-
Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC (2008) Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells. Arterioscler Thromb Vasc Biol 28: 105-111. CrossRef Medline
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 105-111
-
-
Miao, R.Q.1
Fontana, J.2
Fulton, D.3
Lin, M.I.4
Harrison, K.D.5
Sessa, W.C.6
-
53
-
-
0032535245
-
Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
CrossRef Medline
-
Morimoto RI (1998) Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev 12: 3788-3796. CrossRef Medline
-
(1998)
Genes Dev
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
54
-
-
77949884097
-
Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases
-
CrossRef Medline
-
Nagai Y, Fujikake N, Popiel HA, Wada K (2010) Induction of molecular chaperones as a therapeutic strategy for the polyglutamine diseases. Curr Pharm Biotechnol 11: 188-197. CrossRef Medline
-
(2010)
Curr Pharm Biotechnol
, vol.11
, pp. 188-197
-
-
Nagai, Y.1
Fujikake, N.2
Popiel, H.A.3
Wada, K.4
-
55
-
-
75749136948
-
Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease
-
CrossRef Medline
-
Neef DW, Turski ML, Thiele DJ (2010) Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease. PLoS Biol 8: e1000291. CrossRef Medline
-
(2010)
PLoS Biol
, vol.8
-
-
Neef, D.W.1
Turski, M.L.2
Thiele, D.J.3
-
56
-
-
82455210670
-
Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases
-
CrossRef Medline
-
Neef DW, Jaeger AM, Thiele DJ (2011) Heat shock transcription factor 1 as a therapeutic target in neurodegenerative diseases. Nat Rev Drug Discov 10: 930-944. CrossRef Medline
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 930-944
-
-
Neef, D.W.1
Jaeger, A.M.2
Thiele, D.J.3
-
57
-
-
2342652188
-
Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation
-
CrossRef Medline
-
Nollen EA, Garcia SM, van Haaften G, Kim S, Chavez A, Morimoto RI, Plasterk RH (2004) Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Proc Natl Acad Sci U S A 101: 6403-6408. CrossRef Medline
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6403-6408
-
-
Nollen, E.A.1
Garcia, S.M.2
van Haaften, G.3
Kim, S.4
Chavez, A.5
Morimoto, R.I.6
Plasterk, R.H.7
-
58
-
-
0029860750
-
Regulation of Drosophila heat shock factor trimerization: Global sequence requirements and independence of nuclear localization
-
Medline
-
Orosz A, Wisniewski J, Wu C (1996) Regulation of Drosophila heat shock factor trimerization: Global sequence requirements and independence of nuclear localization. Mol Cell Biol 16: 7018-7030. Medline
-
(1996)
Mol Cell Biol
, vol.16
, pp. 7018-7030
-
-
Orosz, A.1
Wisniewski, J.2
Wu, C.3
-
59
-
-
34147149523
-
Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1
-
Medline
-
Ostling P, Björk JK, Roos-Mattjus P, Mezger V, Sistonen L (2007) Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1. J Biol Chem 282: 7077-7086. Medline
-
(2007)
J Biol Chem
, vol.282
, pp. 7077-7086
-
-
Ostling, P.1
Björk, J.K.2
Roos-Mattjus, P.3
Mezger, V.4
Sistonen, L.5
-
60
-
-
33751092252
-
Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival
-
CrossRef Medline
-
Page TJ, Sikder D, Yang L, Pluta L, Wolfinger RD, Kodadek T, Thomas RS (2006) Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Mol Biosyst 2: 627-639. CrossRef Medline
-
(2006)
Mol Biosyst
, vol.2
, pp. 627-639
-
-
Page, T.J.1
Sikder, D.2
Yang, L.3
Pluta, L.4
Wolfinger, R.D.5
Kodadek, T.6
Thomas, R.S.7
-
61
-
-
58149339917
-
Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity
-
CrossRef Medline
-
Pfister JA, Ma C, Morrison BE, D'Mello SR (2008) Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity. PLoS One 3: e4090. CrossRef Medline
-
(2008)
PLoS One
, vol.3
-
-
Pfister, J.A.1
Ma, C.2
Morrison, B.E.3
D'Mello, S.R.4
-
62
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of alzheimer disease amyloid neuropathology by calorie restriction
-
CrossRef Medline
-
Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, Sauve AA, Pasinetti GM (2006) Neuronal SIRT1 activation as a novel mechanism underlying the prevention of alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem 281: 21745-21754. CrossRef Medline
-
(2006)
J Biol Chem
, vol.281
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
Zhao, Z.4
Wang, J.5
Chen, L.6
Zhao, W.7
Thiyagarajan, M.8
McGrogan, D.9
Rodgers, J.T.10
Puigserver, P.11
Sadoshima, J.12
Deng, H.13
Pedrini, S.14
Gandy, S.15
Sauve, A.A.16
Pasinetti, G.M.17
-
63
-
-
0028246870
-
Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
-
Medline
-
Ratan RR, Murphy TH, Baraban JM (1994) Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J Neurosci 14: 4385-4392. Medline
-
(1994)
J Neurosci
, vol.14
, pp. 4385-4392
-
-
Ratan, R.R.1
Murphy, T.H.2
Baraban, J.M.3
-
64
-
-
0026336621
-
Heat shock protects cultured neurons from glutamate toxicity
-
CrossRef Medline
-
Rordorf G, Koroshetz WJ, Bonventre JV (1991) Heat shock protects cultured neurons from glutamate toxicity. Neuron 7: 1043-1051. CrossRef Medline
-
(1991)
Neuron
, vol.7
, pp. 1043-1051
-
-
Rordorf, G.1
Koroshetz, W.J.2
Bonventre, J.V.3
-
65
-
-
84856722935
-
Regulation of cyclooxygenase-2 expression by heat: A novel aspect of heat shock factor 1 function in human cells
-
CrossRef Medline
-
Rossi A, Coccia M, Trotta E, Angelini M, Santoro MG (2012) Regulation of cyclooxygenase-2 expression by heat: A novel aspect of heat shock factor 1 function in human cells. PLoS One 7: e31304. CrossRef Medline
-
(2012)
PLoS One
, vol.7
-
-
Rossi, A.1
Coccia, M.2
Trotta, E.3
Angelini, M.4
Santoro, M.G.5
-
66
-
-
2942525558
-
Enlarged ventricles, astrogliosis and neurodegeneration in heat shock factor 1 null mouse brain
-
CrossRef Medline
-
Santos SD, Saraiva MJ (2004) Enlarged ventricles, astrogliosis and neurodegeneration in heat shock factor 1 null mouse brain. Neuroscience 126: 657-663. CrossRef Medline
-
(2004)
Neuroscience
, vol.126
, pp. 657-663
-
-
Santos, S.D.1
Saraiva, M.J.2
-
67
-
-
51649130437
-
Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease
-
CrossRef Medline
-
Steele AD, Hutter G, Jackson WS, Heppner FL, Borkowski AW, King OD, Raymond GJ, Aguzzi A, Lindquist S (2008) Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease. Proc Natl Acad Sci U S A 105: 13626-13631. CrossRef Medline
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13626-13631
-
-
Steele, A.D.1
Hutter, G.2
Jackson, W.S.3
Heppner, F.L.4
Borkowski, A.W.5
King, O.D.6
Raymond, G.J.7
Aguzzi, A.8
Lindquist, S.9
-
68
-
-
42949125477
-
SIRT1 and neuronal diseases
-
CrossRef Medline
-
Tang BL, Chua CE (2008) SIRT1 and neuronal diseases. Mol Aspects Med 29: 187-200. CrossRef Medline
-
(2008)
Mol Aspects Med
, vol.29
, pp. 187-200
-
-
Tang, B.L.1
Chua, C.E.2
-
69
-
-
1542373742
-
The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response
-
Medline
-
Trinklein ND, Murray JI, Hartman SJ, Botstein D, Myers RM (2004) The role of heat shock transcription factor 1 in the genome-wide regulation of the mammalian heat shock response. Mol Biol Cell 15: 1254-1261. Medline
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1254-1261
-
-
Trinklein, N.D.1
Murray, J.I.2
Hartman, S.J.3
Botstein, D.4
Myers, R.M.5
-
70
-
-
79954992107
-
Hsp70 and its molecular role in nervous system diseases
-
Medline
-
Turturici G, Sconzo G, Geraci F (2011) Hsp70 and its molecular role in nervous system diseases. Biochem Res Int 2011: 618127. Medline
-
(2011)
Biochem Res Int
, pp. 618127
-
-
Turturici, G.1
Sconzo, G.2
Geraci, F.3
-
71
-
-
41949097891
-
C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging
-
CrossRef Medline
-
van Ham TJ, Thijssen KL, Breitling R, Hofstra RM, Plasterk RH, Nollen EA (2008) C. elegans model identifies genetic modifiers of alpha-synuclein inclusion formation during aging. PLoS Genet 4: e1000027. CrossRef Medline
-
(2008)
PLoS Genet
, vol.4
-
-
van Ham, T.J.1
Thijssen, K.L.2
Breitling, R.3
Hofstra, R.M.4
Plasterk, R.H.5
Nollen, E.A.6
-
72
-
-
0038320258
-
Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis
-
CrossRef Medline
-
Wang G, Zhang J, Moskophidis D, Mivechi NF (2003) Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis. Genesis 36: 48-61. CrossRef Medline
-
(2003)
Genesis
, vol.36
, pp. 48-61
-
-
Wang, G.1
Zhang, J.2
Moskophidis, D.3
Mivechi, N.F.4
-
73
-
-
59249098430
-
An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans
-
CrossRef Medline
-
Wang J, Farr GW, Hall DH, Li F, Furtak K, Dreier L, Horwich AL (2009) An ALS-linked mutant SOD1 produces a locomotor defect associated with aggregation and synaptic dysfunction when expressed in neurons of Caenorhabditis elegans. PLoS Genet 5: e1000350. CrossRef Medline
-
(2009)
PLoS Genet
, vol.5
-
-
Wang, J.1
Farr, G.W.2
Hall, D.H.3
Li, F.4
Furtak, K.5
Dreier, L.6
Horwich, A.L.7
-
74
-
-
0032727617
-
Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70
-
CrossRef Medline
-
Warrick JM, Chan HY, Gray-Board GL, Chai Y, Paulson HL, Bonini NM (1999) Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70. Nat Genet 23: 425-428. CrossRef Medline
-
(1999)
Nat Genet
, vol.23
, pp. 425-428
-
-
Warrick, J.M.1
Chan, H.Y.2
Gray-Board, G.L.3
Chai, Y.4
Paulson, H.L.5
Bonini, N.M.6
-
75
-
-
27144503120
-
17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration
-
CrossRef Medline
-
Waza M, Adachi H, Katsuno M, Minamiyama M, Sang C, Tanaka F, Inukai A, Doyu M, Sobue G (2005) 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration. Nat Med 11: 1088-1095. CrossRef Medline
-
(2005)
Nat Med
, vol.11
, pp. 1088-1095
-
-
Waza, M.1
Adachi, H.2
Katsuno, M.3
Minamiyama, M.4
Sang, C.5
Tanaka, F.6
Inukai, A.7
Doyu, M.8
Sobue, G.9
-
76
-
-
60749101582
-
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
CrossRef Medline
-
Westerheide SD, Anckar J, Stevens SM Jr, Sistonen L, Morimoto RI (2009) Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 323: 1063-1066. CrossRef Medline
-
(2009)
Science
, vol.323
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens Jr., S.M.3
Sistonen, L.4
Morimoto, R.I.5
-
77
-
-
0037266092
-
Apoptosis in cerebellar granule neurons is associated with reduced interaction between CREB-binding protein and NF-kappaB
-
CrossRef Medline
-
Yalcin A, Koulich E, Mohamed S, Liu L, D'Mello SR (2003) Apoptosis in cerebellar granule neurons is associated with reduced interaction between CREB-binding protein and NF-kappaB. J Neurochem 84: 397-408. CrossRef Medline
-
(2003)
J Neurochem
, vol.84
, pp. 397-408
-
-
Yalcin, A.1
Koulich, E.2
Mohamed, S.3
Liu, L.4
D'Mello, S.R.5
-
78
-
-
79955433159
-
TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling
-
CrossRef Medline
-
Zhang T, Mullane PC, Periz G, Wang J (2011) TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling. Hum Mol Genet 20: 1952-1965. CrossRef Medline
-
(2011)
Hum Mol Genet
, vol.20
, pp. 1952-1965
-
-
Zhang, T.1
Mullane, P.C.2
Periz, G.3
Wang, J.4
-
79
-
-
77955643169
-
Molecular mechanisms and potential therapeutical targets in huntington's disease
-
CrossRef Medline
-
Zuccato C, Valenza M, Cattaneo E (2010) Molecular mechanisms and potential therapeutical targets in huntington's disease. Physiol Rev 90: 905-981. CrossRef Medline
-
(2010)
Physiol Rev
, vol.90
, pp. 905-981
-
-
Zuccato, C.1
Valenza, M.2
Cattaneo, E.3
|