메뉴 건너뛰기




Volumn 37, Issue 4, 2010, Pages 1875-1881

Dominant-positive HSF1 decreases alpha-synuclein level and alpha-synuclein-induced toxicity

Author keywords

Alpha synuclein; Heat shock protein; HSF1; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; HEAT SHOCK PROTEIN 70; HEAT SHOCK TRANSCRIPTION FACTOR 1; PLASMID DNA; DNA BINDING PROTEIN; HEAT SHOCK TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR;

EID: 77953175438     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9623-2     Document Type: Article
Times cited : (28)

References (30)
  • 1
    • 0345119026 scopus 로고    scopus 로고
    • Caught in the act: Alpha-synuclein is the culprit in Parkinson's disease
    • doi:10.1016/S0896-6273(03) 00684-6
    • Eriksen JL, Dawson TM, Dickson DW, Petrucelli L (2003) Caught in the act: Alpha-synuclein is the culprit in Parkinson's disease. Neuron 40:453-456. doi:10.1016/S0896-6273(03) 00684-6
    • (2003) Neuron , vol.40 , pp. 453-456
    • Eriksen, J.L.1    Dawson, T.M.2    Dickson, D.W.3    Petrucelli, L.4
  • 2
    • 33750364430 scopus 로고    scopus 로고
    • Alpha-synuclein overexpression model
    • doi: 10.1007/978-3-211-45295-0-44
    • Mochizuki H, Yamada M, Mizuno Y (2006) Alpha-synuclein overexpression model. J Neural Transm Suppl 70:281-284. doi: 10.1007/978-3-211-45295-0-44
    • (2006) J Neural Transm Suppl , vol.70 , pp. 281-284
    • Mochizuki, H.1    Yamada, M.2    Mizuno, Y.3
  • 3
    • 0034595728 scopus 로고    scopus 로고
    • Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon- derived cells
    • doi:10.1016/ S0006-89930002215-0
    • Zhou W, Hurlbert MS, Schaack J, Prasad KN, Freed CR (2000) Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon- derived cells. Brain Res 866:33-43. doi:10.1016/ S0006-8993(00)02215-0
    • (2000) Brain Res , vol.866 , pp. 33-43
    • Zhou, W.1    Hurlbert, M.S.2    Schaack, J.3    Prasad, K.N.4    Freed, C.R.5
  • 6
    • 0037130450 scopus 로고    scopus 로고
    • Animal models of PD: Pieces of the same puzzle?
    • DOI 10.1016/S0896-6273(02)00780-8
    • Dawson T, Mandir A, Lee M (2002) Animal models of PD: pieces of the same puzzle? Neuron 35:219-222. doi:10.1016/ S0896-6273(02)00780-8 (Pubitemid 34876725)
    • (2002) Neuron , vol.35 , Issue.2 , pp. 219-222
    • Dawson, T.M.1    Mandir, A.S.2    Lee, M.K.3
  • 7
    • 0034704752 scopus 로고    scopus 로고
    • A Drosophila model of Parkinson's disease
    • DOI 10.1038/35006074
    • Feany MB, Bender WW (2000) A Drosophila model of Parkinson's disease. Nature 404:394-398. doi:10.1038/35006074 (Pubitemid 30164341)
    • (2000) Nature , vol.404 , Issue.6776 , pp. 394-398
    • Feany, M.B.1    Bender, W.W.2
  • 8
    • 0345189364 scopus 로고    scopus 로고
    • Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology
    • DOI 10.1126/science.1090439
    • Outeiro TF, Lindquist S (2003) Yeast cells provide insight into alpha-synuclein biology and pathobiology. Science 302:1772-1775. doi:10.1126/science.1090439 (Pubitemid 37505742)
    • (2003) Science , vol.302 , Issue.5651 , pp. 1772-1775
    • Outeiro, T.F.1    Lindquist, S.2
  • 10
    • 0036846119 scopus 로고    scopus 로고
    • TorsinA and heat shock proteins act as molecular chaperones: Suppression of alpha-synuclein aggregation
    • doi:10.1046/j. 1471-4159.2002.01190.x
    • McLean PJ, Kawamata H, Shariff S, Hewett J, Sharma N, Ueda K, Breakefield XO, Hyman BT (2002) TorsinA and heat shock proteins act as molecular chaperones: Suppression of alpha-synuclein aggregation. J Neurochem 83:846-854. doi:10.1046/j. 1471-4159.2002.01190.x
    • (2002) J Neurochem , vol.83 , pp. 846-854
    • McLean, P.J.1    Kawamata, H.2    Shariff, S.3    Hewett, J.4    Sharma, N.5    Ueda, K.6    Breakefield, X.O.7    Hyman, B.T.8
  • 11
    • 1642356755 scopus 로고    scopus 로고
    • HSP27 but not HSP70 has a potent protective effect against alpha-synucleininduced cell death in mammalian neuronal cells
    • Zourlidou A, Payne Smith MD, Latchman DS (2004) HSP27 but not HSP70 has a potent protective effect against alpha-synucleininduced cell death in mammalian neuronal cells. J Neurochem 88:1439-1448
    • (2004) J Neurochem , vol.88 , pp. 1439-1448
    • Zourlidou, A.1    Payne Smith, M.D.2    Latchman, D.S.3
  • 12
    • 4344569643 scopus 로고    scopus 로고
    • Geldanamycin induces Hsp70 and prevents α-synuclein aggregation and toxicity in vitro
    • DOI 10.1016/j.bbrc.2004.07.021, PII S0006291X04015128
    • McLean PJ, Klucken J, Shin Y, Hyman BT (2004) Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro. Biochem Biophys Res Commun 321:665-669. doi:10.1016/j.bbrc.2004.07.021 (Pubitemid 39127407)
    • (2004) Biochemical and Biophysical Research Communications , vol.321 , Issue.3 , pp. 665-669
    • McLean, P.J.1    Klucken, J.2    Shin, Y.3    Hyman, B.T.4
  • 13
    • 0036468432 scopus 로고    scopus 로고
    • Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
    • DOI 10.1126/science.1067389
    • Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM (2002) Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295:865-868. doi:10.1126/science.1067389 (Pubitemid 34118369)
    • (2002) Science , vol.295 , Issue.5556 , pp. 865-868
    • Auluck, P.K.1    Chan, H.Y.E.2    Trojanowski, J.Q.3    Lee, V.M.-Y.4    Bonini, N.M.5
  • 14
    • 17644383748 scopus 로고    scopus 로고
    • Heat shock protein 70 inhibits α-synuclein fibril formation via preferential binding to prefibrillar species
    • DOI 10.1074/jbc.M413024200
    • Dedmon MM, Christodoulou J, Wilson MR, Dobson CM (2005) Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species. J Biol Chem 280:14733-14740. doi:10.1074/jbc.M413024200 (Pubitemid 40562821)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.15 , pp. 14733-14740
    • Dedmon, M.M.1    Christodoulou, J.2    Wilson, M.R.3    Dobson, C.M.4
  • 15
    • 11844290684 scopus 로고    scopus 로고
    • Dominant-positive and dominant-negative heat shock factors
    • doi:10.1016/j.ymeth. 2004.08.010
    • Voellmy R (2005) Dominant-positive and dominant-negative heat shock factors. Methods 35:199-207. doi:10.1016/j.ymeth. 2004.08.010
    • (2005) Methods , vol.35 , pp. 199-207
    • Voellmy, R.1
  • 16
    • 0032466067 scopus 로고    scopus 로고
    • Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis
    • DOI 10.1046/j.1460-9568.1998.00339.x
    • Wagstaff MJ, Smith J, Collaco-Moraes Y, de Belleroche JS, Voellmy R, Coffin RS, Latchman DS (1998) Delivery of a constitutively active form of the heat shock factor using a virus vector protects neuronal cells from thermal or ischaemic stress but not from apoptosis. Eur J NeuroSci 10:3343-3350. doi: 10.1046/j.1460-9568.1998.00339.x (Pubitemid 29074125)
    • (1998) European Journal of Neuroscience , vol.10 , Issue.11 , pp. 3343-3350
    • Wagstaff, M.J.D.1
  • 17
    • 27144524290 scopus 로고    scopus 로고
    • Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models
    • DOI 10.1074/jbc.M506288200
    • Fujimoto M, Takaki E, Hayashi T, Kitaura Y, Tanaka Y, Inouye S, Nakai A (2005) Active HSF1 significantly suppresses polyglutamine aggregate formation in cellular and mouse models. J Biol Chem 280:34908-34916. doi:10.1074/jbc. M506288200 (Pubitemid 41504625)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.41 , pp. 34908-34916
    • Fujimoto, M.1    Takaki, E.2    Hayashi, T.3    Kitaura, Y.4    Tanaka, Y.5    Inouye, S.6    Nakai, A.7
  • 18
    • 0035859226 scopus 로고    scopus 로고
    • α-Synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons
    • DOI 10.1016/S0306-4522(01)00113-0, PII S0306452201001130
    • McLean PJ, Kawamata H, Hyman BT (2001) Alpha-synucleinenhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons. Neuroscience 104:901-912. doi:10.1016/S0306-4522(01)00113-0 (Pubitemid 32607439)
    • (2001) Neuroscience , vol.104 , Issue.3 , pp. 901-912
    • McLean, P.J.1    Kawamata, H.2    Hyman, B.T.3
  • 19
    • 13244267202 scopus 로고    scopus 로고
    • Mechanisms of suppression of {alpha}-synuclein neurotoxicity by geldanamycin in Drosophila
    • doi:10.1074/jbc. M412106200
    • Auluck PK, Meulener MC, Bonini NM (2005) Mechanisms of suppression of {alpha}-synuclein neurotoxicity by geldanamycin in Drosophila. J Biol Chem 280:2873-2878. doi:10.1074/jbc. M412106200
    • (2005) J Biol Chem , vol.280 , pp. 2873-2878
    • Auluck, P.K.1    Meulener, M.C.2    Bonini, N.M.3
  • 20
    • 44649174333 scopus 로고    scopus 로고
    • Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease
    • Liu F, Nguyen JL, Hulleman JD, Li L, Rochet JC (2008) Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease. J Neurochem 105:2435-2453
    • (2008) J Neurochem , vol.105 , pp. 2435-2453
    • Liu, F.1    Nguyen, J.L.2    Hulleman, J.D.3    Li, L.4    Rochet, J.C.5
  • 22
    • 0035109909 scopus 로고    scopus 로고
    • Effect of the overexpression of wild-type or mutant α-synuclein on cell susceptibility to insult
    • DOI 10.1046/j.1471-4159.2001.00149.x
    • Lee M, Hyun D, Halliwell B, Jenner P (2001) Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult. J Neurochem 76:998-1009. doi:10.1046/j. 1471-4159.2001.00149.x (Pubitemid 32167373)
    • (2001) Journal of Neurochemistry , vol.76 , Issue.4 , pp. 998-1009
    • Lee, M.1    Hyun, D.-H.2    Halliwell, B.3    Jenner, P.4
  • 23
    • 34247603516 scopus 로고    scopus 로고
    • A cell-based model of α-synucleinopathy for screening compounds with therapeutic potential of Parkinson's disease
    • DOI 10.1111/j.1745-7254.2007.00539.x
    • Zhao DL, Zou LB, Zhou LF, Zhu P, Zhu HB (2007) A cell-based model of alpha-synucleinopathy for screening compounds with therapeutic potential of Parkinson's disease. Acta Pharmacol Sin 28:616-626. doi:10.1111/j.1745-7254. 2007.00539.x (Pubitemid 46684012)
    • (2007) Acta Pharmacologica Sinica , vol.28 , Issue.5 , pp. 616-626
    • Zhao, D.-L.1    Zou, L.-B.2    Zhou, L.-F.3    Zhu, P.4    Zhu, H.-B.5
  • 25
    • 32344444326 scopus 로고    scopus 로고
    • Down-regulation of α-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model
    • DOI 10.1016/j.bbrc.2006.01.057, PII S0006291X06001057
    • Hayashita-Kinoh H, Yamada M, Yokota T, Mizuno Y, Mochizuki H (2006) Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model. Biochem Biophys Res Commun 341:1088-1095. doi:10.1016/j.bbrc.2006.01.057 (Pubitemid 43221777)
    • (2006) Biochemical and Biophysical Research Communications , vol.341 , Issue.4 , pp. 1088-1095
    • Hayashita-Kinoh, H.1    Yamada, M.2    Yokota, T.3    Mizuno, Y.4    Mochizuki, H.5
  • 26
    • 33646127577 scopus 로고    scopus 로고
    • Molecular chaperones and protein quality control
    • doi:10.1016/j.cell.2006.04.014
    • Bukau B, Weissman J, Horwich A (2006) Molecular chaperones and protein quality control. Cell 125:443-451. doi:10.1016/j.cell. 2006.04.014
    • (2006) Cell , vol.125 , pp. 443-451
    • Bukau, B.1    Weissman, J.2    Horwich, A.3
  • 27
  • 28
    • 0035006792 scopus 로고    scopus 로고
    • Proteasome inhibition in oxidative stress neurotoxicity: Implications for heat shock proteins
    • DOI 10.1046/j.1471-4159.2001.00302.x
    • Ding Q, Keller JN (2001) Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins. J Neurochem 77:1010-1017. doi:10.1046/j.1471-4159.2001.00302.x (Pubitemid 32467056)
    • (2001) Journal of Neurochemistry , vol.77 , Issue.4 , pp. 1010-1017
    • Ding, Q.1    Keller, J.N.2
  • 29
    • 48249107510 scopus 로고    scopus 로고
    • Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imaging
    • doi:10.1111/j.1471-4159.2008.05407.x
    • Opazo F, Krenz A, Heermann S, Schulz JB, Falkenburger BH (2008) Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imaging. J Neurochem 106:529-540. doi:10.1111/j.1471-4159.2008.05407. x
    • (2008) J Neurochem , vol.106 , pp. 529-540
    • Opazo, F.1    Krenz, A.2    Heermann, S.3    Schulz, J.B.4    Falkenburger, B.H.5
  • 30
    • 33646555755 scopus 로고    scopus 로고
    • + in SK-N-SH cells
    • DOI 10.1016/j.febslet.2006.04.057, PII S001457930600500X
    • Fan GH, Zhou HY, Yang H, Chen SD (2006) Heat shock proteins reduce alpha-synuclein aggregation induced by MPP ? in SK-NSH cells. FEBS Lett 580:3091-3098. doi:10.1016/j.febslet. 2006.04.057 (Pubitemid 43729666)
    • (2006) FEBS Letters , vol.580 , Issue.13 , pp. 3091-3098
    • Fan, G.-H.1    Zhou, H.-Y.2    Yang, H.3    Chen, S.-D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.