-
1
-
-
78650028237
-
The molecular pathology of breast cancer progression
-
Bombonati A, Sgroi DC. The molecular pathology of breast cancer progression. J Pathol. 2011;223(2):307-317.
-
(2011)
J Pathol
, vol.223
, Issue.2
, pp. 307-317
-
-
Bombonati, A.1
Sgroi, D.C.2
-
2
-
-
0043142421
-
The diagnosis and management of pre-invasive breast disease: Fat epithelial atypia - classification, pathologic features and clinical signifcance
-
Schnitt SJ. The diagnosis and management of pre-invasive breast disease: fat epithelial atypia - classification, pathologic features and clinical signifcance. Breast Cancer Res. 2003;5(5):263-268.
-
(2003)
Breast Cancer Res
, vol.5
, Issue.5
, pp. 263-268
-
-
Schnitt, S.J.1
-
3
-
-
34347326186
-
Precursors and preinvasive lesions of the breast: The role of molecular prognostic markers in the diagnostic and therapeutic dilemma
-
Zagouri F, Sergentanis TN, Zografos GC. Precursors and preinvasive lesions of the breast: the role of molecular prognostic markers in the diagnostic and therapeutic dilemma. World J Surg Oncol. 2007; 5:57.
-
(2007)
World J Surg Oncol
, vol.5
, pp. 57
-
-
Zagouri, F.1
Sergentanis, T.N.2
Zografos, G.C.3
-
4
-
-
77951992183
-
Intraductal proliferative lesions of the breast: Morphology, associated risk and molecular biology
-
Ellis IO. Intraductal proliferative lesions of the breast: morphology, associated risk and molecular biology. Mod Pathol. 2010;23 Suppl 2: S1-S7.
-
(2010)
Mod Pathol
, vol.23
, Issue.SUPPL. 2
-
-
Ellis, I.O.1
-
5
-
-
1542375858
-
Multistep tumorigenesis and the microenvironment
-
Schedin P, Elias A. Multistep tumorigenesis and the microenvironment. Breast Cancer Res. 2004;6(2):93-101.
-
(2004)
Breast Cancer Res
, vol.6
, Issue.2
, pp. 93-101
-
-
Schedin, P.1
Elias, A.2
-
6
-
-
84866885625
-
ECM microenviron-ment regulates collective migration and local dissemination in normal and malignant mammary epithelium
-
Nguyen-Ngoc KV, Cheung KJ, Brenot A, et al. ECM microenviron-ment regulates collective migration and local dissemination in normal and malignant mammary epithelium. Proc Natl Acad Sci U S A. 2012; 109(39):E2595-E2604.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.39
-
-
Nguyen-Ngoc, K.V.1
Cheung, K.J.2
Brenot, A.3
-
7
-
-
78549279528
-
Histological, molecular and functional subtypes of breast cancers
-
Malhotra GK, Zhao X, Band H, Band V. Histological, molecular and functional subtypes of breast cancers. Cancer Biol Ther. 2010;10(10): 955-960.
-
(2010)
Cancer Biol Ther
, vol.10
, Issue.10
, pp. 955-960
-
-
Malhotra, G.K.1
Zhao, X.2
Band, H.3
Band, V.4
-
8
-
-
34548863946
-
Identifcation of conserved gene expression features between murine mammary carcinoma models and human breast tumors
-
Herschkowitz JI, Simin K, Weigman VJ, et al. Identifcation of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biol. 2007;8(5):R76.
-
(2007)
Genome Biol
, vol.8
, Issue.5
-
-
Herschkowitz, J.I.1
Simin, K.2
Weigman, V.J.3
-
9
-
-
84886502077
-
Patterns of Recurrence and outcome according to breast cancer subtypes in lymph node-negative disease: Results from international breast cancer study group trials VIII and IX
-
Metzger-Filho O, Sun Z, Viale G, et al. Patterns of Recurrence and outcome according to breast cancer subtypes in lymph node-negative disease: results from international breast cancer study group trials VIII and IX. J Clin Oncol. 2013;31(25):3083-3090.
-
(2013)
J Clin Oncol
, vol.31
, Issue.25
, pp. 3083-3090
-
-
Metzger-Filho, O.1
Sun, Z.2
Viale, G.3
-
10
-
-
66249109653
-
Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics
-
Hennessy BT, Gonzalez-Angulo AM, Stemke-Hale K, et al. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. Cancer Res. 2009;69(10):4116-4124.
-
(2009)
Cancer Res
, vol.69
, Issue.10
, pp. 4116-4124
-
-
Hennessy, B.T.1
Gonzalez-Angulo, A.M.2
Stemke-Hale, K.3
-
11
-
-
72749103664
-
Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
-
Visvader JE. Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis. Genes Dev. 2009;23(22):2563-2577.
-
(2009)
Genes Dev
, vol.23
, Issue.22
, pp. 2563-2577
-
-
Visvader, J.E.1
-
12
-
-
84874615488
-
Breast fbroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics
-
Dumont N, Liu B, Deflippis RA, et al. Breast fbroblasts modulate early dissemination, tumorigenesis, and metastasis through alteration of extracellular matrix characteristics. Neoplasia. 2013;15(3):249-262.
-
(2013)
Neoplasia
, vol.15
, Issue.3
, pp. 249-262
-
-
Dumont, N.1
Liu, B.2
Deflippis, R.A.3
-
13
-
-
52949139787
-
Seeding and propagation of untransformed mouse mammary cells in the lung
-
Podsypanina K, Du YC, Jechlinger M, Beverly LJ, Hambardzumyan D, Varmus H. Seeding and propagation of untransformed mouse mammary cells in the lung. Science. 2008;321(5897):1841-1844.
-
(2008)
Science
, vol.321
, Issue.5897
, pp. 1841-1844
-
-
Podsypanina, K.1
Du, Y.C.2
Jechlinger, M.3
Beverly, L.J.4
Hambardzumyan, D.5
Varmus, H.6
-
14
-
-
0141679385
-
Prolonged dormancy and site-specifc growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fuorescent protein
-
Goodison S, Kawai K, Hihara J, et al. Prolonged dormancy and site-specifc growth potential of cancer cells spontaneously disseminated from nonmetastatic breast tumors as revealed by labeling with green fuorescent protein. Clin Cancer Res. 2003;9(10 Pt 1):3808-3814.
-
(2003)
Clin Cancer Res
, vol.9
, Issue.10 PART 1
, pp. 3808-3814
-
-
Goodison, S.1
Kawai, K.2
Hihara, J.3
-
15
-
-
84877575862
-
Polarity proteins as regulators of cell junction complexes: Implications for breast cancer
-
Bazzoun D, Lelièvre S, Talhouk R. Polarity proteins as regulators of cell junction complexes: implications for breast cancer. Pharmacol Ther. 2013;138(3):418-427.
-
(2013)
Pharmacol Ther
, vol.138
, Issue.3
, pp. 418-427
-
-
Bazzoun, D.1
Lelièvre, S.2
Talhouk, R.3
-
16
-
-
84870221288
-
The apical polarity protein network in Drosophila epithelial cells: Regulation of polarity, junctions, morphogenesis, cell growth, and survival
-
Tepass U. The apical polarity protein network in Drosophila epithelial cells: regulation of polarity, junctions, morphogenesis, cell growth, and survival. Annu Rev Cell Dev Biol. 2012;28:655-685.
-
(2012)
Annu Rev Cell Dev Biol
, vol.28
, pp. 655-685
-
-
Tepass, U.1
-
17
-
-
0034617129
-
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
-
Bilder D, Li M, Perrimon N. Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science. 2000; 289(5476):113-116.
-
(2000)
Science
, vol.289
, Issue.5476
, pp. 113-116
-
-
Bilder, D.1
Li, M.2
Perrimon, N.3
-
18
-
-
0024284814
-
Identifcation of genes required for cytoplasmic localization in early C. elegans embryos
-
Kemphues KJ, Priess JR, Morton DG, Cheng NS. Identifcation of genes required for cytoplasmic localization in early C. elegans embryos. Cell. 1988;52(3):311-320.
-
(1988)
Cell
, vol.52
, Issue.3
, pp. 311-320
-
-
Kemphues, K.J.1
Priess, J.R.2
Morton, D.G.3
Cheng, N.S.4
-
19
-
-
0035898658
-
The cell polarity protein ASIP/ PAR-3 directly associates with junctional adhesion molecule (JAM)
-
Ebnet K, Suzuki A, Horikoshi Y, et al. The cell polarity protein ASIP/ PAR-3 directly associates with junctional adhesion molecule (JAM). EMBO J. 2001;20(14):3738-3748.
-
(2001)
EMBO J
, vol.20
, Issue.14
, pp. 3738-3748
-
-
Ebnet, K.1
Suzuki, A.2
Horikoshi, Y.3
-
20
-
-
84864955500
-
The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold
-
Yang Z, Xue B, Umitsu M, Ikura M, Muthuswamy SK, Neel BG. The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold. Mol Cell. 2012;47(3):469-483.
-
(2012)
Mol Cell
, vol.47
, Issue.3
, pp. 469-483
-
-
Yang, Z.1
Xue, B.2
Umitsu, M.3
Ikura, M.4
Muthuswamy, S.K.5
Neel, B.G.6
-
21
-
-
33645746316
-
The PAR-aPKC system: Lessons in polarity
-
Suzuki A, Ohno S. The PAR-aPKC system: lessons in polarity. J Cell Sci. 2006;119(Pt 6):979-987.
-
(2006)
J Cell Sci
, vol.119
, Issue.PART 6
, pp. 979-987
-
-
Suzuki, A.1
Ohno, S.2
-
22
-
-
4344699150
-
aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity
-
Suzuki A, Hirata M, Kamimura K, et al. aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity. Curr Biol. 2004;14(16):1425-1435.
-
(2004)
Curr Biol
, vol.14
, Issue.16
, pp. 1425-1435
-
-
Suzuki, A.1
Hirata, M.2
Kamimura, K.3
-
23
-
-
67749111502
-
The LKB1-AMPK pathway: Metabolism and growth control in tumour suppression
-
Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat Rev Cancer. 2009;9(8): 563-575.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.8
, pp. 563-575
-
-
Shackelford, D.B.1
Shaw, R.J.2
-
24
-
-
12144287284
-
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
-
Lizcano JM, Göransson O, Toth R, et al. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J. 2004;23(4):833-843.
-
(2004)
EMBO J
, vol.23
, Issue.4
, pp. 833-843
-
-
Lizcano, J.M.1
Göransson, O.2
Toth, R.3
-
25
-
-
33751204464
-
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
-
Zhang L, Li J, Young LH, Caplan MJ. AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc Natl Acad Sci U S A. 2006;103(46):17272-17277.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.46
, pp. 17272-17277
-
-
Zhang, L.1
Li, J.2
Young, L.H.3
Caplan, M.J.4
-
26
-
-
34250827107
-
Energy-dependent regulation of cell structure by AMP-activated protein kinase
-
Lee JH, Koh H, Kim M, et al. Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature. 2007;447(7147): 1017-1020.
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 1017-1020
-
-
Lee, J.H.1
Koh, H.2
Kim, M.3
-
27
-
-
23744440058
-
Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells
-
Fogg VC, Liu CJ, Margolis B. Multiple regions of Crumbs3 are required for tight junction formation in MCF10A cells. J Cell Sci. 2005;118(Pt 13):2859-2869.
-
(2005)
J Cell Sci
, vol.118
, Issue.PART 13
, pp. 2859-2869
-
-
Fogg, V.C.1
Liu, C.J.2
Margolis, B.3
-
28
-
-
21244431506
-
Junctional recruitment of mammalian Scribble relies on E-cadherin engagement
-
Navarro C, Nola S, Audebert S, et al. Junctional recruitment of mammalian Scribble relies on E-cadherin engagement. Oncogene. 2005;24(27):4330-4339.
-
(2005)
Oncogene
, vol.24
, Issue.27
, pp. 4330-4339
-
-
Navarro, C.1
Nola, S.2
Audebert, S.3
-
29
-
-
29144469472
-
The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin
-
Qin Y, Capaldo C, Gumbiner BM, Macara IG. The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin. J Cell Biol. 2005;171(6):1061-1071.
-
(2005)
J Cell Biol
, vol.171
, Issue.6
, pp. 1061-1071
-
-
Qin, Y.1
Capaldo, C.2
Gumbiner, B.M.3
Macara, I.G.4
-
30
-
-
0034628471
-
Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
-
Bilder D, Perrimon N. Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature. 2000;403(6770):676-680.
-
(2000)
Nature
, vol.403
, Issue.6770
, pp. 676-680
-
-
Bilder, D.1
Perrimon, N.2
-
31
-
-
3142757182
-
Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/ stardust
-
Wang Q, Hurd TW, Margolis B. Tight junction protein Par6 interacts with an evolutionarily conserved region in the amino terminus of PALS1/ stardust. J Biol Chem. 2004;279(29):30715-30721.
-
(2004)
J Biol Chem
, vol.279
, Issue.29
, pp. 30715-30721
-
-
Wang, Q.1
Hurd, T.W.2
Margolis, B.3
-
32
-
-
0037319350
-
Direct interaction of two polarity complexes implicated in epithelial tight junction assembly
-
Hurd TW, Gao L, Roh MH, Macara IG, Margolis B. Direct interaction of two polarity complexes implicated in epithelial tight junction assembly. Nat Cell Biol. 2003;5(2):137-142.
-
(2003)
Nat Cell Biol
, vol.5
, Issue.2
, pp. 137-142
-
-
Hurd, T.W.1
Gao, L.2
Roh, M.H.3
Macara, I.G.4
Margolis, B.5
-
33
-
-
24644490121
-
Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer
-
Eder AM, Sui X, Rosen DG, et al. Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. Proc Natl Acad Sci U S A. 2005; 102(35):12519-12524.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, Issue.35
, pp. 12519-12524
-
-
Eder, A.M.1
Sui, X.2
Rosen, D.G.3
-
34
-
-
24744469442
-
Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity
-
Regala RP, Weems C, Jamieson L, Copland JA, Thompson EA, Fields AP. Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity. J Biol Chem. 2005;280(35): 31109-31115.
-
(2005)
J Biol Chem
, vol.280
, Issue.35
, pp. 31109-31115
-
-
Regala, R.P.1
Weems, C.2
Jamieson, L.3
Copland, J.A.4
Thompson, E.A.5
Fields, A.P.6
-
35
-
-
38049074935
-
Amplifcation of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma
-
Yang YL, Chu JY, Luo ML, et al. Amplifcation of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma. Genes Chromosomes Cancer. 2008;47(2): 127-136.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, Issue.2
, pp. 127-136
-
-
Yang, Y.L.1
Chu, J.Y.2
Luo, M.L.3
-
36
-
-
84885789025
-
PAR6B is required for tight junction formation and activated PKCζ localization in breast cancer
-
Cunliffe HE, Jiang Y, Fornace KM, Yang F, Meltzer PS. PAR6B is required for tight junction formation and activated PKCζ localization in breast cancer. Am J Cancer Res. 2012;2(5):478-491.
-
(2012)
Am J Cancer Res
, vol.2
, Issue.5
, pp. 478-491
-
-
Cunliffe, H.E.1
Jiang, Y.2
Fornace, K.M.3
Yang, F.4
Meltzer, P.S.5
-
37
-
-
77950280030
-
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers
-
Rothenberg SM, Mohapatra G, Rivera MN, et al. A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 2010;70(6):2158-2164.
-
(2010)
Cancer Res
, vol.70
, Issue.6
, pp. 2158-2164
-
-
Rothenberg, S.M.1
Mohapatra, G.2
Rivera, M.N.3
-
38
-
-
84867492985
-
MPP3 inactivation by promoter CpG islands hypermethylation in colorectal carcinogenesis
-
Feng X, Chen K, Ye S, et al. MPP3 inactivation by promoter CpG islands hypermethylation in colorectal carcinogenesis. Cancer Biomark. 2012;11(2-3):99-106.
-
(2012)
Cancer Biomark
, vol.11
, Issue.2-3
, pp. 99-106
-
-
Feng, X.1
Chen, K.2
Ye, S.3
-
39
-
-
35548974844
-
The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
-
Aigner K, Dampier B, Descovich L, et al. The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene. 2007;26(49):6979-6988.
-
(2007)
Oncogene
, vol.26
, Issue.49
, pp. 6979-6988
-
-
Aigner, K.1
Dampier, B.2
Descovich, L.3
-
40
-
-
84867862551
-
Hugl1 and Hugl2 in mammary epithelial cells: Polarity, proliferation, and differentiation
-
Russ A, Louderbough JM, Zarnescu D, Schroeder JA. Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation. PLoS One. 2012;7(10):e47734.
-
(2012)
PLoS One
, vol.7
, Issue.10
-
-
Russ, A.1
Louderbough, J.M.2
Zarnescu, D.3
Schroeder, J.A.4
-
41
-
-
58149473474
-
Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo
-
Galvez AS, Duran A, Linares JF, et al. Protein kinase Czeta represses the interleukin-6 promoter and impairs tumorigenesis in vivo. Mol Cell Biol. 2009;29(1):104-115.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.1
, pp. 104-115
-
-
Galvez, A.S.1
Duran, A.2
Linares, J.F.3
-
42
-
-
84892750439
-
Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis
-
Linch M, Sanz-Garcia M, Rosse C, et al. Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. Carcinogenesis. Epub 2013 Nov 30.
-
(2013)
Epub
, pp. 30
-
-
Linch, M.1
Sanz-Garcia, M.2
Rosse, C.3
-
43
-
-
56349098933
-
Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
-
Zhan L, Rosenberg A, Bergami KC, et al. Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell. 2008;135(5):865-878.
-
(2008)
Cell
, vol.135
, Issue.5
, pp. 865-878
-
-
Zhan, L.1
Rosenberg, A.2
Bergami, K.C.3
-
44
-
-
84864866755
-
Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium
-
Ewald AJ, Huebner RJ, Palsdottir H, et al. Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium. J Cell Sci. 2012;125(Pt 11): 2638-2654.
-
(2012)
J Cell Sci
, vol.125
, Issue.PART 11
, pp. 2638-2654
-
-
Ewald, A.J.1
Huebner, R.J.2
Palsdottir, H.3
-
45
-
-
67149106023
-
The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis
-
McCaffrey LM, Macara IG. The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis. Genes Dev. 2009;23(12):1450-1460.
-
(2009)
Genes Dev
, vol.23
, Issue.12
, pp. 1450-1460
-
-
McCaffrey, L.M.1
Macara, I.G.2
-
46
-
-
84869000970
-
Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis
-
McCaffrey LM, Montalbano J, Mihai C, Macara IG. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell. 2012;22(5):601-614.
-
(2012)
Cancer Cell
, vol.22
, Issue.5
, pp. 601-614
-
-
McCaffrey, L.M.1
Montalbano, J.2
Mihai, C.3
Macara, I.G.4
-
47
-
-
84873410310
-
Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion
-
Xue B, Krishnamurthy K, Allred DC, Muthuswamy SK. Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. Nat Cell Biol. 2013;15(2):189-200.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.2
, pp. 189-200
-
-
Xue, B.1
Krishnamurthy, K.2
Allred, D.C.3
Muthuswamy, S.K.4
-
48
-
-
44449152002
-
The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors
-
Kojima Y, Akimoto K, Nagashima Y, et al. The overexpression and altered localization of the atypical protein kinase C lambda/iota in breast cancer correlates with the pathologic type of these tumors. Hum Pathol. 2008;39(6):824-831.
-
(2008)
Hum Pathol
, vol.39
, Issue.6
, pp. 824-831
-
-
Kojima, Y.1
Akimoto, K.2
Nagashima, Y.3
-
49
-
-
84857132136
-
Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity
-
Partanen JI, Tervonen TA, Myllynen M, et al. Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity. Proc Natl Acad Sci U S A. 2012;109(7):E388-E397.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.7
-
-
Partanen, J.I.1
Tervonen, T.A.2
Myllynen, M.3
-
50
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell. 2009;139(5):871-890.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
51
-
-
41649121862
-
Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis
-
Ewald AJ, Brenot A, Duong M, Chan BS, Werb Z. Collective epithelial migration and cell rearrangements drive mammary branching morphogenesis. Dev Cell. 2008;14(4):570-581.
-
(2008)
Dev Cell
, vol.14
, Issue.4
, pp. 570-581
-
-
Ewald, A.J.1
Brenot, A.2
Duong, M.3
Chan, B.S.4
Werb, Z.5
-
52
-
-
84867227049
-
NHERF1/EBP50 controls lactation by establishing basal membrane polarity complexes with prolactin receptor
-
Morales FC, Hayashi Y, van Pelt CS, Georgescu MM. NHERF1/EBP50 controls lactation by establishing basal membrane polarity complexes with prolactin receptor. Cell Death Dis. 2012;3:e391.
-
(2012)
Cell Death Dis
, vol.3
-
-
Morales, F.C.1
Hayashi, Y.2
van Pelt, C.S.3
Georgescu, M.M.4
-
53
-
-
79953293527
-
Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis
-
Durgan J, Kaji N, Jin D, Hall A. Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis. J Biol Chem. 2011;286(14):12461-12474.
-
(2011)
J Biol Chem
, vol.286
, Issue.14
, pp. 12461-12474
-
-
Durgan, J.1
Kaji, N.2
Jin, D.3
Hall, A.4
-
54
-
-
78049255724
-
Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins
-
Hao Y, Du Q, Chen X, et al. Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins. Curr Biol. 2010;20(20):1809-1818.
-
(2010)
Curr Biol
, vol.20
, Issue.20
, pp. 1809-1818
-
-
Hao, Y.1
Du, Q.2
Chen, X.3
-
55
-
-
58149191544
-
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
-
Jaffe AB, Kaji N, Durgan J, Hall A. Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis. J Cell Biol. 2008;183(4):625-633.
-
(2008)
J Cell Biol
, vol.183
, Issue.4
, pp. 625-633
-
-
Jaffe, A.B.1
Kaji, N.2
Durgan, J.3
Hall, A.4
-
56
-
-
24644494270
-
Asymmetric cell divisions promote stratifcation and differentiation of mammalian skin
-
Lechler T, Fuchs E. Asymmetric cell divisions promote stratifcation and differentiation of mammalian skin. Nature. 2005;437(7056): 275-280.
-
(2005)
Nature
, vol.437
, Issue.7056
, pp. 275-280
-
-
Lechler, T.1
Fuchs, E.2
-
57
-
-
77951174042
-
LGN regulates mitotic spindle orientation during epithelial morphogenesis
-
Zheng Z, Zhu H, Wan Q, et al. LGN regulates mitotic spindle orientation during epithelial morphogenesis. J Cell Biol. 2010;189(2): 275-288.
-
(2010)
J Cell Biol
, vol.189
, Issue.2
, pp. 275-288
-
-
Zheng, Z.1
Zhu, H.2
Wan, Q.3
-
58
-
-
79151469101
-
Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions
-
Žigman M, Trinh le A, Fraser SE, Moens CB. Zebrafish neural tube morphogenesis requires Scribble-dependent oriented cell divisions. Curr Biol. 2011;21(1):79-86.
-
(2011)
Curr Biol
, vol.21
, Issue.1
, pp. 79-86
-
-
Žigman, M.1
Trinh Le, A.2
Fraser, S.E.3
Moens, C.B.4
-
59
-
-
84881663995
-
Epithelial junctions maintain tissue architecture by directing planar spindle orientation
-
Nakajima Y, Meyer EJ, Kroesen A, McKinney SA, Gibson MC. Epithelial junctions maintain tissue architecture by directing planar spindle orientation. Nature. 2013;500(7462):359-362.
-
(2013)
Nature
, vol.500
, Issue.7462
, pp. 359-362
-
-
Nakajima, Y.1
Meyer, E.J.2
Kroesen, A.3
McKinney, S.A.4
Gibson, M.C.5
-
60
-
-
8344271193
-
Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins
-
Du Q, Macara IG. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell. 2004;119(4):503-516.
-
(2004)
Cell
, vol.119
, Issue.4
, pp. 503-516
-
-
Du, Q.1
Macara, I.G.2
-
61
-
-
84883802078
-
Discs large links spindle orientation to apical-basal polarity in Drosophila epithelia
-
Bergstralh DT, Lovegrove HE, St Johnston D. Discs large links spindle orientation to apical-basal polarity in Drosophila epithelia. Curr Biol. 2013;23(17):1707-1712.
-
(2013)
Curr Biol
, vol.23
, Issue.17
, pp. 1707-1712
-
-
Bergstralh, D.T.1
Lovegrove, H.E.2
St Johnston, D.3
-
62
-
-
70149120831
-
Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells
-
Johnston CA, Hirono K, Prehoda KE, Doe CQ. Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells. Cell. 2009;138(6):1150-1163.
-
(2009)
Cell
, vol.138
, Issue.6
, pp. 1150-1163
-
-
Johnston, C.A.1
Hirono, K.2
Prehoda, K.E.3
Doe, C.Q.4
-
63
-
-
84887625953
-
Mechanisms of spindle positioning: Cortical force generators in the limelight
-
Kotak S, Gönczy P. Mechanisms of spindle positioning: cortical force generators in the limelight. Curr Opin Cell Biol. 2013;25:741-748.
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 741-748
-
-
Kotak, S.1
Gönczy, P.2
-
64
-
-
44649150257
-
Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells
-
Taddei I, Deugnier MA, Faraldo MM, et al. Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. Nat Cell Biol. 2008;10(6):716-722.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.6
, pp. 716-722
-
-
Taddei, I.1
Deugnier, M.A.2
Faraldo, M.M.3
-
65
-
-
84871712311
-
An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
-
Akhtar N, Streuli CH. An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium. Nat Cell Biol. 2013;15(1):17-27.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.1
, pp. 17-27
-
-
Akhtar, N.1
Streuli, C.H.2
-
66
-
-
77958492733
-
Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis
-
Warner SJ, Longmore GD. Context-dependent compensatory proliferation in epithelial homeostasis and tumorigenesis. Cell Cycle. 2010;9(20):4037-4038.
-
(2010)
Cell Cycle
, vol.9
, Issue.20
, pp. 4037-4038
-
-
Warner, S.J.1
Longmore, G.D.2
-
67
-
-
77951204672
-
The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia
-
Warner SJ, Yashiro H, Longmore GD. The Cdc42/Par6/aPKC polarity complex regulates apoptosis-induced compensatory proliferation in epithelia. Curr Biol. 2010;20(8):677-686.
-
(2010)
Curr Biol
, vol.20
, Issue.8
, pp. 677-686
-
-
Warner, S.J.1
Yashiro, H.2
Longmore, G.D.3
-
68
-
-
53149149836
-
Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment
-
Feng W, Wu H, Chan LN, Zhang M. Par-3-mediated junctional localization of the lipid phosphatase PTEN is required for cell polarity establishment. J Biol Chem. 2008;283(34):23440-23449.
-
(2008)
J Biol Chem
, vol.283
, Issue.34
, pp. 23440-23449
-
-
Feng, W.1
Wu, H.2
Chan, L.N.3
Zhang, M.4
-
69
-
-
77953575215
-
Identification of focal adhesion kinase (FAK) and phosphatidylinositol 3-kinase (PI3-kinase) as Par3 partners by proteomic analysis
-
Itoh N, Nakayama M, Nishimura T, et al. Identification of focal adhesion kinase (FAK) and phosphatidylinositol 3-kinase (PI3-kinase) as Par3 partners by proteomic analysis. Cytoskeleton (Hoboken). 2010;67(5):297-308.
-
(2010)
Cytoskeleton (Hoboken)
, vol.67
, Issue.5
, pp. 297-308
-
-
Itoh, N.1
Nakayama, M.2
Nishimura, T.3
-
70
-
-
74049107249
-
PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality
-
López-Knowles E, O'Toole SA, McNeil CM, et al. PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality. Int J Cancer. 2010;126(5):1121-1131.
-
(2010)
Int J Cancer
, vol.126
, Issue.5
, pp. 1121-1131
-
-
López-Knowles, E.1
O'Toole, S.A.2
McNeil, C.M.3
-
71
-
-
84864869386
-
Repression of cancer cell senescence by PKCι
-
Paget JA, Restall IJ, Daneshmand M, et al. Repression of cancer cell senescence by PKCι. Oncogene. 2012;31(31):3584-3596.
-
(2012)
Oncogene
, vol.31
, Issue.31
, pp. 3584-3596
-
-
Paget, J.A.1
Restall, I.J.2
Daneshmand, M.3
-
72
-
-
4344618713
-
Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells
-
Castoria G, Migliaccio A, Di Domenico M, et al. Role of atypical protein kinase C in estradiol-triggered G1/S progression of MCF-7 cells. Mol Cell Biol. 2004;24(17):7643-7653.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.17
, pp. 7643-7653
-
-
Castoria, G.1
Migliaccio, A.2
Di Domenico, M.3
-
73
-
-
67649770134
-
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation
-
Chan SW, Lim CJ, Loo LS, Chong YF, Huang C, Hong W. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. J Biol Chem. 2009;284(21):14347-14358.
-
(2009)
J Biol Chem
, vol.284
, Issue.21
, pp. 14347-14358
-
-
Chan, S.W.1
Lim, C.J.2
Loo, L.S.3
Chong, Y.F.4
Huang, C.5
Hong, W.6
-
74
-
-
84866274900
-
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
-
Lamar JM, Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain. Proc Natl Acad Sci U S A. 2012;109(37):E2441-E2450.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.37
-
-
Lamar, J.M.1
Stern, P.2
Liu, H.3
Schindler, J.W.4
Jiang, Z.G.5
Hynes, R.O.6
-
75
-
-
84892702028
-
Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer
-
Vlug EJ, van de Ven RA, Vermeulen JF, Bult P, van Diest PJ, Derksen PW. Nuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancer. Cell Oncol (Dordr). 2013;36(5):375-384.
-
(2013)
Cell Oncol (Dordr)
, vol.36
, Issue.5
, pp. 375-384
-
-
Vlug, E.J.1
van de Ven, R.A.2
Vermeulen, J.F.3
Bult, P.4
van Diest, P.J.5
Derksen, P.W.6
-
76
-
-
53849087493
-
Expression of Yes-associated protein in common solid tumors
-
Steinhardt AA, Gayyed MF, Klein AP, et al. Expression of Yes-associated protein in common solid tumors. Hum Pathol. 2008;39(11): 1582-1589.
-
(2008)
Hum Pathol
, vol.39
, Issue.11
, pp. 1582-1589
-
-
Steinhardt, A.A.1
Gayyed, M.F.2
Klein, A.P.3
-
77
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M, Zanconato F, Azzolin L, et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell. 2011;147(4):759-772.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
-
78
-
-
54049121368
-
Yes-associated protein (YAP) functions as a tumor suppressor in breast
-
Yuan M, Tomlinson V, Lara R, et al. Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death Differ. 2008;15(11): 1752-1759.
-
(2008)
Cell Death Differ
, vol.15
, Issue.11
, pp. 1752-1759
-
-
Yuan, M.1
Tomlinson, V.2
Lara, R.3
-
79
-
-
47549095853
-
TEAD mediates YAP-dependent gene induction and growth control
-
Zhao B, Ye X, Yu J, et al. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev. 2008;22(14):1962-1971.
-
(2008)
Genes Dev
, vol.22
, Issue.14
, pp. 1962-1971
-
-
Zhao, B.1
Ye, X.2
Yu, J.3
-
80
-
-
57749084642
-
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop
-
Lapi E, Di Agostino S, Donzelli S, et al. PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell. 2008;32(6):803-814.
-
(2008)
Mol Cell
, vol.32
, Issue.6
, pp. 803-814
-
-
Lapi, E.1
Di Agostino, S.2
Donzelli, S.3
-
81
-
-
84872690692
-
The Hippo size control pathway - ever expanding
-
Lin JI, Poon CL, Harvey KF. The Hippo size control pathway - ever expanding. Sci Signal. 2013;6(259):p e4.
-
(2013)
Sci Signal
, vol.6
, Issue.259
-
-
Lin, J.I.1
Poon, C.L.2
Harvey, K.F.3
-
82
-
-
84859852225
-
Growth control by committee: Intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling
-
Boggiano JC, Fehon RG. Growth control by committee: intercellular junctions, cell polarity, and the cytoskeleton regulate Hippo signaling. Dev Cell. 2012;22(4):695-702.
-
(2012)
Dev Cell
, vol.22
, Issue.4
, pp. 695-702
-
-
Boggiano, J.C.1
Fehon, R.G.2
-
83
-
-
78649969033
-
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway
-
Varelas X, Samavarchi-Tehrani P, Narimatsu M, et al. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Dev Cell. 2010;19(6):831-844.
-
(2010)
Dev Cell
, vol.19
, Issue.6
, pp. 831-844
-
-
Varelas, X.1
Samavarchi-Tehrani, P.2
Narimatsu, M.3
-
84
-
-
84884291548
-
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
-
Yin F, Yu J, Zheng Y, Chen Q, Zhang N, Pan D. Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell. 2013;154(6):1342-1355.
-
(2013)
Cell
, vol.154
, Issue.6
, pp. 1342-1355
-
-
Yin, F.1
Yu, J.2
Zheng, Y.3
Chen, Q.4
Zhang, N.5
Pan, D.6
-
85
-
-
84876158761
-
KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals
-
Moleirinho S, Chang N, Sims AH, et al. KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals. Oncogene. 2013;32(14):1821-1830.
-
(2013)
Oncogene
, vol.32
, Issue.14
, pp. 1821-1830
-
-
Moleirinho, S.1
Chang, N.2
Sims, A.H.3
-
86
-
-
79955484868
-
KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells
-
Yoshihama Y, Sasaki K, Horikoshi Y, et al. KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells. Curr Biol. 2011;21(8):705-711.
-
(2011)
Curr Biol
, vol.21
, Issue.8
, pp. 705-711
-
-
Yoshihama, Y.1
Sasaki, K.2
Horikoshi, Y.3
-
87
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded
-
Yu J, Zheng Y, Dong J, Klusza S, Deng WM, Pan D. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded. Dev Cell. 2010;18(2):288-299.
-
(2010)
Dev Cell
, vol.18
, Issue.2
, pp. 288-299
-
-
Yu, J.1
Zheng, Y.2
Dong, J.3
Klusza, S.4
Deng, W.M.5
Pan, D.6
-
88
-
-
75749146306
-
Plasticity of cell migration: A multiscale tuning model
-
Friedl P, Wolf K. Plasticity of cell migration: a multiscale tuning model. J Cell Biol. 2010;188(1):11-19.
-
(2010)
J Cell Biol
, vol.188
, Issue.1
, pp. 11-19
-
-
Friedl, P.1
Wolf, K.2
-
89
-
-
84873811988
-
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
-
Yu M, Bardia A, Wittner BS, et al. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science. 2013;339(6119):580-584.
-
(2013)
Science
, vol.339
, Issue.6119
, pp. 580-584
-
-
Yu, M.1
Bardia, A.2
Wittner, B.S.3
-
90
-
-
39049160267
-
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
-
Spaderna S, Schmalhofer O, Wahlbuhl M, et al. The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res. 2008;68(2):537-544.
-
(2008)
Cancer Res
, vol.68
, Issue.2
, pp. 537-544
-
-
Spaderna, S.1
Schmalhofer, O.2
Wahlbuhl, M.3
-
91
-
-
84875212117
-
The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis
-
Kashyap A, Zimmerman T, Ergül N, et al. The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis. Oncogene. 2013;32(11):1396-1407.
-
(2013)
Oncogene
, vol.32
, Issue.11
, pp. 1396-1407
-
-
Kashyap, A.1
Zimmerman, T.2
Ergül, N.3
-
92
-
-
77956230322
-
The ZEB/miR-200 feedback loop - a motor of cellular plasticity in development and cancer?
-
Brabletz S, Brabletz T. The ZEB/miR-200 feedback loop - a motor of cellular plasticity in development and cancer? EMBO Rep. 2010;11(9): 670-677.
-
(2010)
EMBO Rep
, vol.11
, Issue.9
, pp. 670-677
-
-
Brabletz, S.1
Brabletz, T.2
-
93
-
-
43049103824
-
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
-
Gregory PA, Bert AG, Paterson EL, et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol. 2008;10(5):593-601.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.5
, pp. 593-601
-
-
Gregory, P.A.1
Bert, A.G.2
Paterson, E.L.3
-
94
-
-
84878662952
-
Epithelial cell differentiation regulated by MicroRNA-200a in mammary glands
-
Nagaoka K, Zhang H, Watanabe G, Taya K. Epithelial cell differentiation regulated by MicroRNA-200a in mammary glands. PLoS One. 2013;8(6):e65127.
-
(2013)
PLoS One
, vol.8
, Issue.6
-
-
Nagaoka, K.1
Zhang, H.2
Watanabe, G.3
Taya, K.4
-
95
-
-
84860015579
-
Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells
-
Chatterjee S, Seifried L, Feigin ME, et al. Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cells. PLoS One. 2012;7(4):e34343.
-
(2012)
PLoS One
, vol.7
, Issue.4
-
-
Chatterjee, S.1
Seifried, L.2
Feigin, M.E.3
-
96
-
-
14844364701
-
Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity
-
Ozdamar B, Bose R, Barrios-Rodiles M, Wang HR, Zhang Y, Wrana JL. Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity. Science. 2005;307(5715): 1603-1609.
-
(2005)
Science
, vol.307
, Issue.5715
, pp. 1603-1609
-
-
Ozdamar, B.1
Bose, R.2
Barrios-Rodiles, M.3
Wang, H.R.4
Zhang, Y.5
Wrana, J.L.6
-
97
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133(4): 704-715.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
98
-
-
79955030842
-
Breast cancer stem cells: A new challenge for breast cancer treatment
-
Jain P, Alahari SK. Breast cancer stem cells: a new challenge for breast cancer treatment. Front Biosci (Landmark Ed). 2011;16:1824-1832.
-
(2011)
Front Biosci (Landmark Ed)
, vol.16
, pp. 1824-1832
-
-
Jain, P.1
Alahari, S.K.2
-
99
-
-
33750505436
-
Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control
-
Aranda V, Haire T, Nolan ME, et al. Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol. 2006;8(11):1235-1245.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.11
, pp. 1235-1245
-
-
Aranda, V.1
Haire, T.2
Nolan, M.E.3
-
100
-
-
54249140140
-
The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer
-
Nolan ME, Aranda V, Lee S, et al. The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer. Cancer Res. 2008;68(20):8201-8209.
-
(2008)
Cancer Res
, vol.68
, Issue.20
, pp. 8201-8209
-
-
Nolan, M.E.1
Aranda, V.2
Lee, S.3
-
101
-
-
77951781454
-
A novel role for 14-3-3 sigma in regulating epithelial cell polarity
-
Ling C, Zuo D, Xue B, Muthuswamy S, Muller WJ. A novel role for 14-3-3 sigma in regulating epithelial cell polarity. Genes Dev. 2010;24(9):947-956.
-
(2010)
Genes Dev
, vol.24
, Issue.9
, pp. 947-956
-
-
Ling, C.1
Zuo, D.2
Xue, B.3
Muthuswamy, S.4
Muller, W.J.5
-
102
-
-
84865772261
-
Loss of the 14-3-3σ tumor suppressor is a critical event in ErbB2-mediated tumor progression
-
Ling C, Su VM, Zuo D, Muller WJ. Loss of the 14-3-3σ tumor suppressor is a critical event in ErbB2-mediated tumor progression. Cancer Discov. 2012;2(1):68-81.
-
(2012)
Cancer Discov
, vol.2
, Issue.1
, pp. 68-81
-
-
Ling, C.1
Su, V.M.2
Zuo, D.3
Muller, W.J.4
-
103
-
-
84879804592
-
LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway
-
Zhuang Z, Wang K, Cheng X, et al. LKB1 inhibits breast cancer partially through repressing the Hedgehog signaling pathway. PLoS One. 2013;8(7):e67431.
-
(2013)
PLoS One
, vol.8
, Issue.7
-
-
Zhuang, Z.1
Wang, K.2
Cheng, X.3
-
104
-
-
0036726312
-
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium
-
Weaver VM, Lelièvre S, Lakins JN, et al. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002;2(3):205-216.
-
(2002)
Cancer Cell
, vol.2
, Issue.3
, pp. 205-216
-
-
Weaver, V.M.1
Lelièvre, S.2
Lakins, J.N.3
-
105
-
-
56649124726
-
Tiam1-defciency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice
-
Strumane K, Rygiel T, van der Valk M, Collard JG. Tiam1-defciency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice. J Cancer Res Clin Oncol. 2009;135(1):69-80.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, Issue.1
, pp. 69-80
-
-
Strumane, K.1
Rygiel, T.2
van der Valk, M.3
Collard, J.G.4
-
106
-
-
69549128378
-
A role for the TGFbeta-Par6 polarity pathway in breast cancer progression
-
Viloria-Petit AM, David L, Jia JY, et al. A role for the TGFbeta-Par6 polarity pathway in breast cancer progression. Proc Natl Acad Sci U S A. 2009;106(33):14028-14033.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.33
, pp. 14028-14033
-
-
Viloria-Petit, A.M.1
David, L.2
Jia, J.Y.3
-
107
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490(7418):61-70.
-
(2012)
Nature
, vol.490
, Issue.7418
, pp. 61-70
-
-
-
108
-
-
84880769933
-
Localization, not important in all tumor-suppressing properties: A lesson learnt from scribble
-
Elsum IA, Humbert PO. Localization, not important in all tumor-suppressing properties: a lesson learnt from scribble. Cells Tissues Organs. 2013;198(1):1-11.
-
(2013)
Cells Tissues Organs
, vol.198
, Issue.1
, pp. 1-11
-
-
Elsum, I.A.1
Humbert, P.O.2
-
109
-
-
27244455638
-
Biological variables and prognosis of DCIS
-
van de Vijver MJ. Biological variables and prognosis of DCIS. Breast. 2005;14(6):509-519.
-
(2005)
Breast
, vol.14
, Issue.6
, pp. 509-519
-
-
van de Vijver, M.J.1
-
110
-
-
84870159400
-
Phosphorylation-dependent protein-protein interaction modules as potential molecular targets for cancer therapy
-
Watanabe N, Osada H. Phosphorylation-dependent protein-protein interaction modules as potential molecular targets for cancer therapy. Curr Drug Targets. 2012;13(13):1654-1658.
-
(2012)
Curr Drug Targets
, vol.13
, Issue.13
, pp. 1654-1658
-
-
Watanabe, N.1
Osada, H.2
-
111
-
-
84875617207
-
Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes
-
Kjær S, Linch M, Purkiss A, et al. Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes. Biochem J. 2013;451(2):329-342.
-
(2013)
Biochem J
, vol.451
, Issue.2
, pp. 329-342
-
-
Kjær, S.1
Linch, M.2
Purkiss, A.3
-
112
-
-
33748802758
-
Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ciota
-
Erdogan E, Lamark T, Stallings-Mann M, et al. Aurothiomalate inhibits transformed growth by targeting the PB1 domain of protein kinase Ciota. J Biol Chem. 2006;281(38):28450-28459.
-
(2006)
J Biol Chem
, vol.281
, Issue.38
, pp. 28450-28459
-
-
Erdogan, E.1
Lamark, T.2
Stallings-Mann, M.3
-
113
-
-
79953232778
-
A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma
-
Pillai P, Desai S, Patel R, et al. A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma. Int J Biochem Cell Biol. 2011;43(5):784-794.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, Issue.5
, pp. 784-794
-
-
Pillai, P.1
Desai, S.2
Patel, R.3
-
114
-
-
44849097288
-
aPKC inhibitors might be the sensitizer of chemotherapy and adoptive immunotherapy in the treatment of hASIPa-overexpressed breast cancer
-
Jin YT, Ying XX, Hu YH, Zou Q, Wang HY, Xu YH. aPKC inhibitors might be the sensitizer of chemotherapy and adoptive immunotherapy in the treatment of hASIPa-overexpressed breast cancer. Oncol Res. 2008;17(2):59-68.
-
(2008)
Oncol Res
, vol.17
, Issue.2
, pp. 59-68
-
-
Jin, Y.T.1
Ying, X.X.2
Hu, Y.H.3
Zou, Q.4
Wang, H.Y.5
Xu, Y.H.6
-
115
-
-
84863116087
-
Comparative oncogenomics identifes breast tumors enriched in functional tumor-initiating cells
-
Herschkowitz JI, Zhao W, Zhang M, et al. Comparative oncogenomics identifes breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A. 2012;109(8):2778-2783.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.8
, pp. 2778-2783
-
-
Herschkowitz, J.I.1
Zhao, W.2
Zhang, M.3
-
116
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133(4): 704-715.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
117
-
-
0037388204
-
Prospective identifcation of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identifcation of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A. 2003;100(7):3983-3988.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
118
-
-
78049308800
-
Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer
-
Prat A, Parker JS, Karginova O, et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer. Breast Cancer Res. 2010;12(5):R68.
-
(2010)
Breast Cancer Res
, vol.12
, Issue.5
-
-
Prat, A.1
Parker, J.S.2
Karginova, O.3
-
119
-
-
70349123829
-
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
-
Cicalese A, Bonizzi G, Pasi CE, et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell. 2009;138(6):1083-1095.
-
(2009)
Cell
, vol.138
, Issue.6
, pp. 1083-1095
-
-
Cicalese, A.1
Bonizzi, G.2
Pasi, C.E.3
-
120
-
-
78649439321
-
Asymmetric cell division: Recent developments and their implications for tumour biology
-
Knoblich JA. Asymmetric cell division: recent developments and their implications for tumour biology. Nat Rev Mol Cell Biol. 2010;11(12):849-860.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, Issue.12
, pp. 849-860
-
-
Knoblich, J.A.1
|