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Volumn 2, Issue 1, 2012, Pages 68-81

Loss of the 14-3-3σ tumor suppressor is a critical event in ErbB2-mediated tumor progression

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GENOMIC DNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE B; RAF PROTEIN; STRATIFIN;

EID: 84865772261     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-11-0189     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 0031954313 scopus 로고    scopus 로고
    • neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group
    • Andrulis IL, Bull SB, Blackstein ME, Sutherland D, Mak C, Sidlofsky S, et al. neu/erbB-2 amplification identifies a poor-prognosis group of women with node-negative breast cancer. Toronto Breast Cancer Study Group. J Clin Oncol 1998;16:1340-9.
    • (1998) J Clin Oncol , vol.16 , pp. 1340-1349
    • Andrulis, I.L.1    Bull, S.B.2    Blackstein, M.E.3    Sutherland, D.4    Mak, C.5    Sidlofsky, S.6
  • 2
    • 37049183697 scopus 로고
    • Human breast cancer:Correlation of relapse and survival with the amplification of the HER2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A McGuire, WL. Human breast cancer:correlation of relapse and survival with the amplification of the HER2/neu oncogene. Science 1987;235:177-82.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 4
    • 0034690033 scopus 로고    scopus 로고
    • Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation
    • Brandt R, Eisenbrandt R, Leenders F, Zschiesche W, Binas B, Juergensen C, et al. Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation. Oncogene 2000;19:2129-37.
    • (2000) Oncogene , vol.19 , pp. 2129-2137
    • Brandt, R.1    Eisenbrandt, R.2    Leenders, F.3    Zschiesche, W.4    Binas, B.5    Juergensen, C.6
  • 5
    • 0025372023 scopus 로고
    • Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice
    • Matsui Y, Halter SA, Holt JT, Hogan BL, Coffey RJ. Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice. Cell 1990;61:1147-55.
    • (1990) Cell , vol.61 , pp. 1147-1155
    • Matsui, Y.1    Halter, S.A.2    Holt, J.T.3    Hogan, B.L.4    Coffey, R.J.5
  • 6
    • 0025297086 scopus 로고
    • Overexpression of TGF alpha in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast
    • Sandgren EP, Luetteke NC, Palmiter RD, Brinster RL, Lee DC. Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast. Cell 1990;61:1121-35.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.D.3    Brinster, R.L.4    Lee, D.C.5
  • 7
    • 0029102871 scopus 로고
    • Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice
    • Sandgren EP, Schroeder JA, Qui TH, Palmiter RD, Brinster RL, Lee DC. Inhibition of mammary gland involution is associated with transforming growth factor alpha but not c-myc-induced tumorigenesis in transgenic mice. Cancer Res 1995;55:3915-27.
    • (1995) Cancer Res , vol.55 , pp. 3915-3927
    • Sandgren, E.P.1    Schroeder, J.A.2    Qui, T.H.3    Palmiter, R.D.4    Brinster, R.L.5    Lee, D.C.6
  • 8
    • 0024405949 scopus 로고
    • Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene
    • Bouchard L, Lamarre L, Tremblay PJ, Jolicoeur P. Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene. Cell 1989;57:931-6.
    • (1989) Cell , vol.57 , pp. 931-936
    • Bouchard, L.1    Lamarre, L.2    Tremblay, P.J.3    Jolicoeur, P.4
  • 9
    • 0029997433 scopus 로고    scopus 로고
    • Activated neu induces rapid tumor progression
    • Guy CT, Cardiff RD, Muller WJ. Activated neu induces rapid tumor progression. J Biol Chem 1996;271:7673-8.
    • (1996) J Biol Chem , vol.271 , pp. 7673-7678
    • Guy, C.T.1    Cardiff, R.D.2    Muller, W.J.3
  • 10
    • 0026633920 scopus 로고
    • Early and multifocal tumors in breast, salivary, harderian and epididymal tissues developed in MMTY-Neu transgenic mice
    • Lucchini F, Sacco MG, Hu N, Villa A, Brown J, Cesano L, et al. Early and multifocal tumors in breast, salivary, harderian and epididymal tissues developed in MMTY-Neu transgenic mice. Cancer Lett 1992;64:203-9.
    • (1992) Cancer Lett , vol.64 , pp. 203-209
    • Lucchini, F.1    Sacco, M.G.2    Hu, N.3    Villa, A.4    Brown, J.5    Cesano, L.6
  • 11
    • 0023713558 scopus 로고
    • Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene
    • Muller WJ, Sinn E, Pattengale PK, Wallace R, Leder P. Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell 1988;54:105-15.
    • (1988) Cell , vol.54 , pp. 105-115
    • Muller, W.J.1    Sinn, E.2    Pattengale, P.K.3    Wallace, R.4    Leder, P.5
  • 12
    • 0033561296 scopus 로고    scopus 로고
    • Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: Implications for human breast cancer
    • Siegel PM, Ryan ED, Cardiff RD, Muller WJ. Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. Embo J 1999;18:2149-64.
    • (1999) Embo J , vol.18 , pp. 2149-2164
    • Siegel, P.M.1    Ryan, E.D.2    Cardiff, R.D.3    Muller, W.J.4
  • 13
    • 0025215079 scopus 로고
    • Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer
    • Lemoine NR, Staddon S, Dickson C, Barnes DM, Gullick WJ. Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer. Oncogene 1990;5:237-9.
    • (1990) Oncogene , vol.5 , pp. 237-239
    • Lemoine, N.R.1    Staddon, S.2    Dickson, C.3    Barnes, D.M.4    Gullick, W.J.5
  • 15
    • 85047696060 scopus 로고    scopus 로고
    • Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu
    • Montagna C, Andrechek ER, Padilla-Nash H, Muller WJ, Ried T. Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu. Oncogene 2002;21:890-8.
    • (2002) Oncogene , vol.21 , pp. 890-898
    • Montagna, C.1    Andrechek, E.R.2    Padilla-Nash, H.3    Muller, W.J.4    Ried, T.5
  • 16
    • 37549048594 scopus 로고    scopus 로고
    • An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer
    • Dillon RL, Brown ST, Ling C, Shioda T, Muller WJ. An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Mol Cell Biol 2007;27:8648-57.
    • (2007) Mol Cell Biol , vol.27 , pp. 8648-8657
    • Dillon, R.L.1    Brown, S.T.2    Ling, C.3    Shioda, T.4    Muller, W.J.5
  • 17
    • 27544442628 scopus 로고    scopus 로고
    • Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling
    • Hodgson JG, Malek T, Bornstein S, Hariono S, Ginzinger DG, Muller WJ, et al. Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling. Cancer Res 2005;65:9695-704.
    • (2005) Cancer Res , vol.65 , pp. 9695-9704
    • Hodgson, J.G.1    Malek, T.2    Bornstein, S.3    Hariono, S.4    Ginzinger, D.G.5    Muller, W.J.6
  • 19
    • 0028918250 scopus 로고
    • Detection and cloning of a common region of loss of heterozygosity at chromosome 1p in breast cancer
    • Nagai H, Negrini M, Carter SL, Gillum DR, Rosenberg AL, Schwartz GF, et al. Detection and cloning of a common region of loss of heterozygosity at chromosome 1p in breast cancer. Cancer Res 1995;55:1752-7.
    • (1995) Cancer Res , vol.55 , pp. 1752-1757
    • Nagai, H.1    Negrini, M.2    Carter, S.L.3    Gillum, D.R.4    Rosenberg, A.L.5    Schwartz, G.F.6
  • 20
    • 0026901457 scopus 로고
    • Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells
    • Prasad GL, Valverius EM, McDuffie E, Cooper HL. Complementary DNA cloning of a novel epithelial cell marker protein, HME1, that may be down-regulated in neoplastic mammary cells. Cell Growth Differ 1992;3:507-13.
    • (1992) Cell Growth Differ , vol.3 , pp. 507-513
    • Prasad, G.L.1    Valverius, E.M.2    McDuffie, E.3    Cooper, H.L.4
  • 24
    • 0033533612 scopus 로고    scopus 로고
    • 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
    • Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B. 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 1999;401:616-20.
    • (1999) Nature , vol.401 , pp. 616-620
    • Chan, T.A.1    Hermeking, H.2    Lengauer, C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 25
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006;10:515-27.
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 26
    • 27644529779 scopus 로고    scopus 로고
    • A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice
    • Herron BJ, Liddell RA, Parker A, Grant S, Kinne J, Fisher JK, et al. A mutation in stratifin is responsible for the repeated epilation (Er) phenotype in mice. Nat Genet 2005;37:1210-2.
    • (2005) Nat Genet , vol.37 , pp. 1210-1212
    • Herron, B.J.1    Liddell, R.A.2    Parker, A.3    Grant, S.4    Kinne, J.5    Fisher, J.K.6
  • 27
    • 27644525123 scopus 로고    scopus 로고
    • Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse
    • Li Q, Lu Q, Estepa G, Verma IM. Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse. Proc Natl Acad Sci U S A 2005;102:15977-82.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 15977-15982
    • Li, Q.1    Lu, Q.2    Estepa, G.3    Verma, I.M.4
  • 28
    • 77951781454 scopus 로고    scopus 로고
    • A novel role for 14-3-3sigma in regulating epithelial cell polarity
    • Ling C, Zuo D, Xue B, Muthuswamy S, Muller WJ. A novel role for 14-3-3sigma in regulating epithelial cell polarity. Genes Dev 2010;24:947-56.
    • (2010) Genes Dev , vol.24 , pp. 947-956
    • Ling, C.1    Zuo, D.2    Xue, B.3    Muthuswamy, S.4    Muller, W.J.5
  • 29
    • 40949130063 scopus 로고    scopus 로고
    • ShcA signalling is essential for tumour progression in mouse models of human breast cancer
    • Ursini-Siegel J, Hardy WR, Zuo D, Lam SH, Sanguin-Gendreau V, Cardiff RD, et al. ShcA signalling is essential for tumour progression in mouse models of human breast cancer. Embo J 2008;27:910-20.
    • (2008) Embo J , vol.27 , pp. 910-920
    • Ursini-Siegel, J.1    Hardy, W.R.2    Zuo, D.3    Lam, S.H.4    Sanguin-Gendreau, V.5    Cardiff, R.D.6
  • 30
    • 0027400599 scopus 로고
    • Introduction to the genetics of primary renal tumors in children
    • Knudson AG Jr. Introduction to the genetics of primary renal tumors in children. Med Pediatr Oncol 1993;21:193-8.
    • (1993) Med Pediatr Oncol , vol.21 , pp. 193-198
    • Knudson Jr., A.G.1
  • 32
    • 59149095847 scopus 로고    scopus 로고
    • Regulation of RAF activity by 14-3-3 proteins: RAF kinases associate functionally with both homo-and heterodimeric forms of 14-3-3 proteins
    • Fischer A, Baljuls A, Reinders J, Nekhoroshkova E, Sibilski C, Metz R, et al. Regulation of RAF activity by 14-3-3 proteins: RAF kinases associate functionally with both homo-and heterodimeric forms of 14-3-3 proteins. J Biol Chem 2009;284:3183-94.
    • (2009) J Biol Chem , vol.284 , pp. 3183-3194
    • Fischer, A.1    Baljuls, A.2    Reinders, J.3    Nekhoroshkova, E.4    Sibilski, C.5    Metz, R.6
  • 33
    • 0023631608 scopus 로고
    • Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivo
    • Sinn E, Muller W, Pattengale P, Tepler I, Wallace R, Leder P. Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell 1987;49:465-75.
    • (1987) Cell , vol.49 , pp. 465-475
    • Sinn, E.1    Muller, W.2    Pattengale, P.3    Tepler, I.4    Wallace, R.5    Leder, P.6
  • 35
    • 0025969655 scopus 로고
    • Expression of c-erbB-2 oncoprotein in salivary gland tumours: An immunohistochemical study
    • Kernohan NM, Blessing K, King G, Corbett IP, Miller ID. Expression of c-erbB-2 oncoprotein in salivary gland tumours: an immunohistochemical study. J Pathol 1991;163:77-80.
    • (1991) J Pathol , vol.163 , pp. 77-80
    • Kernohan, N.M.1    Blessing, K.2    King, G.3    Corbett, I.P.4    Miller, I.D.5
  • 36
    • 0024563889 scopus 로고
    • Expression pattern of the neu (NGL) gene-encoded growth factor receptor protein (p185neu) in normal and transformed epithelial tissues of the digestive tract
    • Cohen JA, Weiner DB, More KF, Kokai Y, Williams WV, Maguire HC Jr, et al. Expression pattern of the neu (NGL) gene-encoded growth factor receptor protein (p185neu) in normal and transformed epithelial tissues of the digestive tract. Oncogene 1989;4:81-8.
    • (1989) Oncogene , vol.4 , pp. 81-88
    • Cohen, J.A.1    Weiner, D.B.2    More, K.F.3    Kokai, Y.4    Williams, W.V.5    Maguire Jr., H.C.6
  • 37
    • 0010066582 scopus 로고
    • A v-erbBrelated protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma
    • Semba K, Kamata N, Toyoshima K, Yamamoto T. A v-erbBrelated protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc Natl Acad Sci U S A 1985;82:6497-501.
    • (1985) Proc Natl Acad Sci U S A , vol.82 , pp. 6497-6501
    • Semba, K.1    Kamata, N.2    Toyoshima, K.3    Yamamoto, T.4
  • 38
    • 5044234175 scopus 로고    scopus 로고
    • Frequent downregulation of 14-3-3 sigma protein and hypermethylation of 14-3-3 sigma gene in salivary gland adenoid cystic carcinoma
    • Uchida D, Begum NM, Almofti A, Kawamata H, Yoshida H, Sato M. Frequent downregulation of 14-3-3 sigma protein and hypermethylation of 14-3-3 sigma gene in salivary gland adenoid cystic carcinoma. Br J Cancer 2004;91:1131-8.
    • (2004) Br J Cancer , vol.91 , pp. 1131-1138
    • Uchida, D.1    Begum, N.M.2    Almofti, A.3    Kawamata, H.4    Yoshida, H.5    Sato, M.6
  • 39
    • 0031984788 scopus 로고    scopus 로고
    • Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins
    • Cullere X, Rose P, Thathamangalam U, Chatterjee A, Mullane KP, Pallas DC, et al. Serine 257 phosphorylation regulates association of polyomavirus middle T antigen with 14-3-3 proteins. J Virol 1998;72:558-63.
    • (1998) J Virol , vol.72 , pp. 558-563
    • Cullere, X.1    Rose, P.2    Thathamangalam, U.3    Chatterjee, A.4    Mullane, K.P.5    Pallas, D.C.6
  • 40
    • 0037142070 scopus 로고    scopus 로고
    • Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth
    • Urano T, Saito T, Tsukui T, Fujita M, Hosoi T, Muramatsu M, et al. Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth. Nature 2002;417:871-5.
    • (2002) Nature , vol.417 , pp. 871-875
    • Urano, T.1    Saito, T.2    Tsukui, T.3    Fujita, M.4    Hosoi, T.5    Muramatsu, M.6
  • 41
    • 24344457712 scopus 로고    scopus 로고
    • The role of epigenetic inactivation of 14-3-3sigma in human cancer
    • Lodygin D, Hermeking H. The role of epigenetic inactivation of 14-3-3sigma in human cancer. Cell Res 2005;15:237-46.
    • (2005) Cell Res , vol.15 , pp. 237-246
    • Lodygin, D.1    Hermeking, H.2
  • 42
    • 69249240289 scopus 로고    scopus 로고
    • 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelialmesenchymal transition
    • Lu J, Guo H, Treekitkarnmongkol W, Li P, Zhang J, Shi B, et al. 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelialmesenchymal transition. Cancer Cell 2009;16:195-207.
    • (2009) Cancer Cell , vol.16 , pp. 195-207
    • Lu, J.1    Guo, H.2    Treekitkarnmongkol, W.3    Li, P.4    Zhang, J.5    Shi, B.6
  • 43
    • 0344663968 scopus 로고    scopus 로고
    • Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia
    • Hurd TW, Fan S, Liu CJ, Kweon HK, Hakansson K, Margolis B. Phosphorylation-dependent binding of 14-3-3 to the polarity protein Par3 regulates cell polarity in mammalian epithelia. Curr Biol 2003;13:2082-90.
    • (2003) Curr Biol , vol.13 , pp. 2082-2090
    • Hurd, T.W.1    Fan, S.2    Liu, C.J.3    Kweon, H.K.4    Hakansson, K.5    Margolis, B.6
  • 44
    • 33750505436 scopus 로고    scopus 로고
    • Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control
    • Aranda V, Haire T, Nolan ME, Calarco JP, Rosenberg AZ, Fawcett JP, et al. Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol 2006;8:1235-45.
    • (2006) Nat Cell Biol , vol.8 , pp. 1235-1245
    • Aranda, V.1    Haire, T.2    Nolan, M.E.3    Calarco, J.P.4    Rosenberg, A.Z.5    Fawcett, J.P.6
  • 45
    • 56349098933 scopus 로고    scopus 로고
    • Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
    • Zhan L, Rosenberg A, Bergami KC, Yu M, Xuan Z, Jaffe AB, et al. Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 2008;135:865-78.
    • (2008) Cell , vol.135 , pp. 865-878
    • Zhan, L.1    Rosenberg, A.2    Bergami, K.C.3    Yu, M.4    Xuan, Z.5    Jaffe, A.B.6
  • 46
    • 33646897898 scopus 로고    scopus 로고
    • Epigenetic silencing of 14-3-3sigma in cancer
    • Lodygin D, Hermeking H. Epigenetic silencing of 14-3-3sigma in cancer. Semin Cancer Biol 2006;16:214-24.
    • (2006) Semin Cancer Biol , vol.16 , pp. 214-224
    • Lodygin, D.1    Hermeking, H.2


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