Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium

Journal of Cell Science

Volumn 125, Issue 11, 2012, Pages 2638-2654

  Ewald, Andrew J ^a,b   Huebner, Robert J ^b   Palsdottir, Hildur ^c   Lee, Jessie K ^c   Perez, Melissa J ^c   Jorgens, Danielle M ^c   Tauscher, Andrew N ^c   Cheung, Kevin J ^b   Werb, Zena ^a   Auer, Manfred ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Apico basal polarity; Breast cancer; Epithelial morphogenesis; Mammary gland

Indexed keywords

BETA CATENIN; PAR3 PROTEIN; PROTEIN; PROTEIN KINASE C ZETA; RHO KINASE; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BASOLATERAL MEMBRANE; BREAST CELL; BREAST EPITHELIUM; CANCER GROWTH; CELL ADHESION; CELL CONTACT; CELL JUNCTION; CELL LABELING; CELL MEMBRANE; CELL MIGRATION; CELL POLARITY; CELL SHAPE; CONTROLLED STUDY; CYTOPLASM; DESMOSOME; ELECTRON MICROSCOPY; ENZYME INHIBITION; ENZYME LOCALIZATION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FEMALE; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; TIGHT JUNCTION; ULTRASTRUCTURE ANALYSIS AND ELECTRON MICROSCOPY;

AMIDES; ANIMALS; CELL COMMUNICATION; CELL MEMBRANE; CELL MOVEMENT; CELL POLARITY; CELL SHAPE; CELL SURFACE EXTENSIONS; COLLAGEN; DESMOSOMES; DRUG COMBINATIONS; EPITHELIAL CELLS; EPITHELIUM; EXTRACELLULAR MATRIX; FEMALE; LAMININ; MAMMARY GLANDS, ANIMAL; MICE; MODELS, BIOLOGICAL; MORPHOGENESIS; MYOSIN-LIGHT-CHAIN KINASE; ORGANOIDS; PROTEOGLYCANS; PYRIDINES; RAC GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; TIGHT JUNCTIONS; TISSUE CULTURE TECHNIQUES;

EID: 84864866755     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.096875     Document Type: Article

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