Atypical PKCι contributes to poor prognosis through loss of apical-basal polarity and Cyclin E overexpression in ovarian cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 35, 2005, Pages 12519-12524

  Eder, Astrid M ^a   Sui, Xiaomei ^a   Rosen, Daniel G ^a   Nolden, Laura K ^a   Cheng, Kwai Wa ^a   Lahad, John P ^a   Kango Singh, Madhuri ^a   Lu, Karen H ^a   Warneke, Carla L ^a   Atkinson, Edward M ^a   Bedrosian, Isabelle ^a   Keyomarsi, Khandan ^a   Kuo, Wen Lin ^b   Gray, Joe W ^b   Yin, Jerry C P ^c   Liu, Jinsong ^a   Halder, Georg ^a   Mills, Gordon B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Epithelial cell polarity; Proliferation

Indexed keywords

CYCLIN E; PROTEIN KINASE C IOTA; ISOENZYME; PROTEIN KINASE C; PROTEIN KINASE C LAMBDA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CELL POLARITY; CELL PROLIFERATION; CONTROLLED STUDY; DROSOPHILA; DRUG TARGETING; EPITHELIUM CELL; FEMALE; GENE AMPLIFICATION; GENE NUMBER; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IN VIVO STUDY; MAJOR CLINICAL STUDY; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; SURVIVAL RATE; ANIMAL; APOPTOSIS; CYTOLOGY; ENZYMOLOGY; EYE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; ONCOGENE; OVARY TUMOR; PATHOLOGY; RAT; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; CELL POLARITY; CELL PROLIFERATION; CYCLIN E; DROSOPHILA; EYE; FEMALE; GENE AMPLIFICATION; HUMANS; ISOENZYMES; ONCOGENES; OVARIAN NEOPLASMS; PROGNOSIS; PROTEIN KINASE C; RATS;

EID: 24644490121     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505641102     Document Type: Article

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