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Volumn 198, Issue 1, 2013, Pages 1-11

Localization, not important in all tumor-suppressing properties: A lesson learnt from scribble

Author keywords

Epithelia; Epithelial to mesenchymal transition; MCF10A; Mitogen activated proteinkinase; Protein localization; Scribble; Transformation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; TUMOR SUPPRESSOR PROTEIN; BETA CATENIN; F ACTIN; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; VASCULOTROPIN;

EID: 84880769933     PISSN: 14226405     EISSN: 14226421     Source Type: Journal    
DOI: 10.1159/000348423     Document Type: Article
Times cited : (23)

References (38)
  • 2
    • 0034628471 scopus 로고    scopus 로고
    • Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
    • Bilder, D., N. Perrimon (2000) Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature 403: 676-680
    • (2000) Nature , vol.403 , pp. 676-680
    • Bilder, D.1    Perrimon, N.2
  • 3
    • 0242641565 scopus 로고    scopus 로고
    • Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
    • Brumby, A.M., H.E. Richardson (2003) Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila . Embo J 22: 5769-5779
    • (2003) Embo J , vol.22 , pp. 5769-5779
    • Brumby, A.M.1    Richardson, H.E.2
  • 4
    • 0034253594 scopus 로고    scopus 로고
    • LAP proteins: What's up with epithelia?
    • Bryant, P.J., A. Huwe (2000) LAP proteins: what's up with epithelia? Nat Cell Biol 2: E141-E143
    • (2000) Nat Cell Biol , vol.2
    • Bryant, P.J.1    Huwe, A.2
  • 5
    • 34548233208 scopus 로고    scopus 로고
    • Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain
    • Dai, F., C. Chang, X. Lin, P. Dai, L. Mei, X.H. Feng (2007) Erbin inhibits transforming growth factor beta signaling through a novel Smad-interacting domain. Mol Cell Biol 27: 6183-6194
    • (2007) Mol Cell Biol , vol.27 , pp. 6183-6194
    • Dai, F.1    Chang, C.2    Lin, X.3    Dai, P.4    Mei, L.5    Feng, X.H.6
  • 6
    • 79951766734 scopus 로고    scopus 로고
    • Erbin, a Negative Regulator in Diverse Signal Pathways
    • Dan, L., M. Shi, H. Duan, C. Han, N. Guo (2010) Erbin, a Negative Regulator in Diverse Signal Pathways. Curr Protein Pept Sci 11: 759- 764
    • (2010) Curr Protein Pept Sci , vol.11 , pp. 759-764
    • Dan, L.1    Shi, M.2    Duan, H.3    Han, C.4    Guo, N.5
  • 7
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF- 10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath, J., S.K. Muthuswamy, J.S. Brugge (2003) Morphogenesis and oncogenesis of MCF- 10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 30: 256-268
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 9
    • 53649108148 scopus 로고    scopus 로고
    • Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling
    • Dow, L.E., I.A. Elsum, C.L. King, K.M. Kinross, H.E. Richardson, P.O. Humbert (2008) Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling. Oncogene 27: 5988- 6001
    • (2008) Oncogene , vol.27 , pp. 5988-6001
    • Dow, L.E.1    Elsum, I.A.2    King, C.L.3    Kinross, K.M.4    Richardson, H.E.5    Humbert, P.O.6
  • 10
    • 34147094240 scopus 로고    scopus 로고
    • The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
    • Dow, L.E., J.S. Kauffman, J. Caddy, K. Zarbalis, A.S. Peterson, S.M. Jane, S.M. Russell, P.O. Humbert (2007) The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: regulation of Rho GTPase recruitment to the leading edge. Oncogene 26: 2272-2282
    • (2007) Oncogene , vol.26 , pp. 2272-2282
    • Dow, L.E.1    Kauffman, J.S.2    Caddy, J.3    Zarbalis, K.4    Peterson, A.S.5    Jane, S.M.6    Russell, S.M.7    Humbert, P.O.8
  • 12
    • 33747465415 scopus 로고    scopus 로고
    • Human Discs Large and Scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression
    • Gardiol, D., A. Zacchi, F. Petrera, G. Stanta, L. Banks (2006) Human Discs Large and Scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression. Int J Cancer 119: 1285-1290
    • (2006) Int J Cancer , vol.119 , pp. 1285-1290
    • Gardiol, D.1    Zacchi, A.2    Petrera, F.3    Stanta, G.4    Banks, L.5
  • 13
    • 77954865524 scopus 로고    scopus 로고
    • Cell polarity in motion: Redefining mammary tissue organization through EMT and cell polarity transitions
    • Godde, N.J., R.C. Galea, I.A. Elsum, P.O. Humbert (2010) Cell polarity in motion: redefining mammary tissue organization through EMT and cell polarity transitions. J Mammary Gland Biol Neoplasia 15: 149-168
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , pp. 149-168
    • Godde, N.J.1    Galea, R.C.2    Elsum, I.A.3    Humbert, P.O.4
  • 14
    • 76049106434 scopus 로고    scopus 로고
    • Polarity protein alterations in carcinoma: A focus on emerging roles for polarity regulators
    • Huang, L., S.K. Muthuswamy (2010) Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators. Curr Opin Genet Dev 20: 41-50
    • (2010) Curr Opin Genet Dev , vol.20 , pp. 41-50
    • Huang, L.1    Muthuswamy, S.K.2
  • 16
    • 84857219453 scopus 로고    scopus 로고
    • Protein localization in disease and therapy
    • Hung, M.C., W. Link (2011) Protein localization in disease and therapy. J Cell Sci 124: 3381- 3392
    • (2011) J Cell Sci , vol.124 , pp. 3381-3392
    • Hung, M.C.1    Link, W.2
  • 17
    • 0036232188 scopus 로고    scopus 로고
    • Assessment of the ability to model proteins with leucine-rich repeats in light of the latest structural information
    • Kajava, A.V., B. Kobe (2002) Assessment of the ability to model proteins with leucine-rich repeats in light of the latest structural information. Protein Sci 11: 1082-1090
    • (2002) Protein Sci , vol.11 , pp. 1082-1090
    • Kajava, A.V.1    Kobe, B.2
  • 19
    • 67650661180 scopus 로고    scopus 로고
    • Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: An immunohistochemical study
    • Lisovsky, M., K. Dresser, S. Baker, A. Fisher, B. Woda, B. Banner, G.Y. Lauwers (2009) Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: an immunohistochemical study. Mod Pathol 22: 977-984
    • (2009) Mod Pathol , vol.22 , pp. 977-984
    • Lisovsky, M.1    Dresser, K.2    Baker, S.3    Fisher, A.4    Woda, B.5    Banner, B.6    Lauwers, G.Y.7
  • 20
    • 0037805547 scopus 로고    scopus 로고
    • Ras oncogenes: The first 30 years
    • Malumbres, M., M. Barbacid (2003) Ras oncogenes: the first 30 years. Nat Rev Cancer 3: 7-13
    • (2003) Nat Rev Cancer , vol.3 , pp. 7-13
    • Malumbres, M.1    Barbacid, M.2
  • 21
    • 84655169623 scopus 로고    scopus 로고
    • Epithelial cell polarity, stem cells and cancer
    • Martin-Belmonte, F., M. Perez-Moreno (2012) Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer 12: 23-38
    • (2012) Nat Rev Cancer , vol.12 , pp. 23-38
    • Martin-Belmonte, F.1    Perez-Moreno, M.2
  • 23
    • 0842329915 scopus 로고    scopus 로고
    • Analysis of the expression and localisation of a LAP protein, human Scribble, in the normal and neoplastic epithelium of uterine cervix
    • Nakagawa, S., T. Yano, K. Nakagawa, S. Takizawa, Y. Suzuki, T. Yasugi, J.M. Huibregtse, Y. Taketani (2004) Analysis of the expression and localisation of a LAP protein, human Scribble, in the normal and neoplastic epithelium of uterine cervix. Br J Cancer 90: 194-199
    • (2004) Br J Cancer , vol.90 , pp. 194-199
    • Nakagawa, S.1    Yano, T.2    Nakagawa, K.3    Takizawa, S.4    Suzuki, Y.5    Yasugi, T.6    Huibregtse, J.M.7    Taketani, Y.8
  • 24
    • 0242666126 scopus 로고    scopus 로고
    • A genetic screen in Drosophila for metastatic behavior
    • Pagliarini, R.A., T. Xu (2003) A genetic screen in Drosophila for metastatic behavior. Science 302: 1227-1231
    • (2003) Science , vol.302 , pp. 1227-1231
    • Pagliarini, R.A.1    Xu, T.2
  • 27
    • 84857782607 scopus 로고    scopus 로고
    • Mutations in the planar cell polarity genes CELSR1 and Scrib are associated with the severe neural tube defect craniorachischisis
    • Robinson, A., S. Escuin, K. Doudney, M. Vekemans, R.E. Stevenson, N.D. Greene, A.J. Copp, P. Stanier (2012) Mutations in the planar cell polarity genes CELSR1 and Scrib are associated with the severe neural tube defect craniorachischisis. Hum Mutat 33: 440-447
    • (2012) Hum Mutat , vol.33 , pp. 440-447
    • Robinson, A.1    Escuin, S.2    Doudney, K.3    Vekemans, M.4    Stevenson, R.E.5    Greene, N.D.6    Copp, A.J.7    Stanier, P.8
  • 29
    • 78649369742 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition (EMT) phenomenon
    • suppl 7
    • Savagner, P. (2010) The epithelial-mesenchymal transition (EMT) phenomenon. Ann Oncol 21(suppl 7): vii89-vii92
    • (2010) Ann Oncol , vol.21
    • Savagner, P.1
  • 30
    • 0032504106 scopus 로고    scopus 로고
    • SUR-8, a conserved Ras-binding protein with leucinerich repeats, positively regulates Ras-mediated signaling in C. Elegans
    • Sieburth, D.S., Q. Sun, M. Han (1998) SUR-8, a conserved Ras-binding protein with leucinerich repeats, positively regulates Ras-mediated signaling in C. elegans . Cell 94: 119-130
    • (1998) Cell , vol.94 , pp. 119-130
    • Sieburth, D.S.1    Sun, Q.2    Han, M.3
  • 31
    • 0035192909 scopus 로고    scopus 로고
    • Involvement of p38 mitogen-activated protein kinase signaling in transformed growth of a cholangiocarcinoma cell line
    • Tadlock, L., T. Patel (2001) Involvement of p38 mitogen-activated protein kinase signaling in transformed growth of a cholangiocarcinoma cell line. Hepatology 33: 43-51
    • (2001) Hepatology , vol.33 , pp. 43-51
    • Tadlock, L.1    Patel, T.2
  • 33
    • 10944257459 scopus 로고    scopus 로고
    • Molecular signaling regulating anchorage-independent growth of cancer cells
    • Wang, L.H. (2004) Molecular signaling regulating anchorage-independent growth of cancer cells. Mt Sinai J Med 71: 361-367
    • (2004) Mt Sinai J Med , vol.71 , pp. 361-367
    • Wang, L.H.1
  • 34
    • 6944248910 scopus 로고    scopus 로고
    • Activation of the ERK pathway is required for TGF-beta1-induced EMT in vitro
    • Xie, L., B.K. Law, A.M. Chytil, K.A. Brown, M.E. Aakre, H.L. Moses (2004) Activation of the ERK pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia 6: 603-610
    • (2004) Neoplasia , vol.6 , pp. 603-610
    • Xie, L.1    Law, B.K.2    Chytil, A.M.3    Brown, K.A.4    Aakre, M.E.5    Moses, H.L.6
  • 35
    • 59449090107 scopus 로고    scopus 로고
    • TGF-betainduced epithelial to mesenchymal transition
    • Xu, J., S. Lamouille, R. Derynck (2009) TGF-betainduced epithelial to mesenchymal transition. Cell Res 19: 156-172
    • (2009) Cell Res , vol.19 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 36
    • 19344362286 scopus 로고    scopus 로고
    • A focused and efficient genetic screening strategy in the mouse: Identification of mutations that disrupt cortical development
    • Zarbalis, K., S.R. May, Y. Shen, M. Ekker, J.L. Rubenstein, A.S. Peterson (2004) A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development. PLoS Biol 2: E219.
    • (2004) PLoS Biol , vol.2
    • Zarbalis, K.1    May, S.R.2    Shen, Y.3    Ekker, M.4    Rubenstein, J.L.5    Peterson, A.S.6
  • 37
    • 11244314036 scopus 로고    scopus 로고
    • Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble
    • Zeitler, J., C.P. Hsu, H. Dionne, D. Bilder (2004) Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble. J Cell Biol 167: 1137-1146
    • (2004) J Cell Biol , vol.167 , pp. 1137-1146
    • Zeitler, J.1    Hsu, C.P.2    Dionne, H.3    Bilder, D.4
  • 38
    • 56349098933 scopus 로고    scopus 로고
    • Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma
    • Zhan, L., A. Rosenberg, K.C. Bergami, M. Yu, Z. Xuan, A.B. Jaffe, C. Allred, S.K. Muthuswamy (2008) Deregulation of scribble promotes mammary tumorigenesis and reveals a role for cell polarity in carcinoma. Cell 135: 865- 878.
    • (2008) Cell , vol.135 , pp. 865-878
    • Zhan, L.1    Rosenberg, A.2    Bergami, K.C.3    Yu, M.4    Xuan, Z.5    Jaffe, A.B.6    Allred, C.7    Muthuswamy, S.K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.