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Volumn 119, Issue 4, 2004, Pages 503-516

Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CELL PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; MICROTUBULE PROTEIN; PROTEIN LGN; PROTEIN NUMA; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN;

EID: 8344271193     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2004.10.028     Document Type: Article
Times cited : (313)

References (38)
  • 1
    • 0029923978 scopus 로고    scopus 로고
    • Metaphase spindles rotate in the neuroepithelium of rat cerebral cortex
    • Adams R.J. Metaphase spindles rotate in the neuroepithelium of rat cerebral cortex. J. Neurosci. 16:1996;7610-7618
    • (1996) J. Neurosci. , vol.16 , pp. 7610-7618
    • Adams, R.J.1
  • 2
    • 0030614352 scopus 로고    scopus 로고
    • NH2-terminal deletion of beta-catenin results in stable colocalization of mutant β-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion
    • Barth A.I., Pollack A.L., Altschuler Y., Mostov K.E., Nelson W.J. NH2-terminal deletion of beta-catenin results in stable colocalization of mutant β-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesion. J. Cell Biol. 136:1997;693-706
    • (1997) J. Cell Biol. , vol.136 , pp. 693-706
    • Barth, A.I.1    Pollack, A.L.2    Altschuler, Y.3    Mostov, K.E.4    Nelson, W.J.5
  • 3
    • 0036897569 scopus 로고    scopus 로고
    • Asymmetric segregation of Numb: A mechanism for neural specification from Drosophila to mammals
    • Cayouette M., Raff M. Asymmetric segregation of Numb. a mechanism for neural specification from Drosophila to mammals Nat. Neurosci. 5:2002;1265-1269
    • (2002) Nat. Neurosci. , vol.5 , pp. 1265-1269
    • Cayouette, M.1    Raff, M.2
  • 4
    • 0038046388 scopus 로고    scopus 로고
    • Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos
    • Colombo K., Grill S.W., Kimple R.J., Willard F.S., Siderovski D.P., Gonczy P. Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryos. Science. 300:2003;1957-1961
    • (2003) Science , vol.300 , pp. 1957-1961
    • Colombo, K.1    Grill, S.W.2    Kimple, R.J.3    Willard, F.S.4    Siderovski, D.P.5    Gonczy, P.6
  • 5
    • 0033782853 scopus 로고    scopus 로고
    • Spindle assembly in animal cells
    • Compton D.A. Spindle assembly in animal cells. Annu. Rev. Biochem. 69:2000;95-114
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 95-114
    • Compton, D.A.1
  • 6
    • 0028986424 scopus 로고
    • Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis
    • Compton D.A., Luo C. Mutation of the predicted p34cdc2 phosphorylation sites in NuMA impair the assembly of the mitotic spindle and block mitosis. J. Cell Sci. 108:1995;621-633
    • (1995) J. Cell Sci. , vol.108 , pp. 621-633
    • Compton, D.A.1    Luo, C.2
  • 7
    • 0026600132 scopus 로고
    • Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis
    • Compton D.A., Szilak I., Cleveland D.W. Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis. J. Cell Biol. 116:1992;1395-1408
    • (1992) J. Cell Biol. , vol.116 , pp. 1395-1408
    • Compton, D.A.1    Szilak, I.2    Cleveland, D.W.3
  • 8
    • 0035141286 scopus 로고    scopus 로고
    • Asymmetric cell division: Fly neuroblast meets worm zygote
    • Doe C.Q., Bowerman B. Asymmetric cell division. fly neuroblast meets worm zygote Curr. Opin. Cell Biol. 13:2001;68-75
    • (2001) Curr. Opin. Cell Biol. , vol.13 , pp. 68-75
    • Doe, C.Q.1    Bowerman, B.2
  • 9
    • 0035205087 scopus 로고    scopus 로고
    • A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization
    • Du Q., Stukenberg P.T., Macara I.G. A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization. Nat. Cell Biol. 3:2001;1069-1075
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1069-1075
    • Du, Q.1    Stukenberg, P.T.2    MacAra, I.G.3
  • 10
    • 0037137429 scopus 로고    scopus 로고
    • LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation
    • Du Q., Taylor L., Compton D.A., Macara I.G. LGN blocks the ability of NuMA to bind and stabilize microtubules. A mechanism for mitotic spindle assembly regulation. Curr. Biol. 12:2002;1928-1933
    • (2002) Curr. Biol. , vol.12 , pp. 1928-1933
    • Du, Q.1    Taylor, L.2    Compton, D.A.3    MacAra, I.G.4
  • 11
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:2001;494-498
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 12
    • 0028877327 scopus 로고
    • NuMA is required for the organization of microtubules into aster-like mitotic arrays
    • Gaglio T., Saredi A., Compton D.A. NuMA is required for the organization of microtubules into aster-like mitotic arrays. J. Cell Biol. 131:1995;693-708
    • (1995) J. Cell Biol. , vol.131 , pp. 693-708
    • Gaglio, T.1    Saredi, A.2    Compton, D.A.3
  • 13
    • 0035809156 scopus 로고    scopus 로고
    • Chromosome movement in mitosis requires microtubule anchorage at spindle poles
    • Gordon M., Howard L., Compton D. Chromosome movement in mitosis requires microtubule anchorage at spindle poles. J. Cell Biol. 152:2001;425-434
    • (2001) J. Cell Biol. , vol.152 , pp. 425-434
    • Gordon, M.1    Howard, L.2    Compton, D.3
  • 14
    • 0034745355 scopus 로고    scopus 로고
    • Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorabditis elegans embryos
    • Gotta M., Ahringer J. Distinct roles for Gα and Gβγ in regulating spindle position and orientation in Caenorabditis elegans embryos. Nat. Cell Biol. 3:2001;297-300
    • (2001) Nat. Cell Biol. , vol.3 , pp. 297-300
    • Gotta, M.1    Ahringer, J.2
  • 15
    • 0037665297 scopus 로고    scopus 로고
    • Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo
    • Gotta M., Dong Y., Peterson Y.K., Lanier S.M., Ahringer J. Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo. Curr. Biol. 13:2003;1029-1037
    • (2003) Curr. Biol. , vol.13 , pp. 1029-1037
    • Gotta, M.1    Dong, Y.2    Peterson, Y.K.3    Lanier, S.M.4    Ahringer, J.5
  • 16
    • 0035252546 scopus 로고    scopus 로고
    • Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo
    • Grill S.W., Gonczy P., Stelzer E.H., Hyman A.A. Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo. Nature. 409:2001;630-633
    • (2001) Nature , vol.409 , pp. 630-633
    • Grill, S.W.1    Gonczy, P.2    Stelzer, E.H.3    Hyman, A.A.4
  • 17
    • 0042845879 scopus 로고    scopus 로고
    • The distribution of active force generators controls mitotic spindle position
    • Grill S.W., Howard J., Schaffer E., Stelzer E.H., Hyman A.A. The distribution of active force generators controls mitotic spindle position. Science. 301:2003;518-521
    • (2003) Science , vol.301 , pp. 518-521
    • Grill, S.W.1    Howard, J.2    Schaffer, E.3    Stelzer, E.H.4    Hyman, A.A.5
  • 18
    • 0036558281 scopus 로고    scopus 로고
    • Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules
    • Haren L., Merdes A. Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules. J. Cell Sci. 115:2002;1815-1824
    • (2002) J. Cell Sci. , vol.115 , pp. 1815-1824
    • Haren, L.1    Merdes, A.2
  • 19
    • 0035513733 scopus 로고    scopus 로고
    • Asymmetric cell division in the Drosophila nervous system
    • Jan Y.N., Jan L.Y. Asymmetric cell division in the Drosophila nervous system. Nat. Rev. Neurosci. 2:2001;772-779
    • (2001) Nat. Rev. Neurosci. , vol.2 , pp. 772-779
    • Jan, Y.N.1    Jan, L.Y.2
  • 20
    • 0034253536 scopus 로고    scopus 로고
    • The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
    • Joberty G., Petersen C., Gao L., Macara I.G. The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42. Nat. Cell Biol. 2:2000;531-539
    • (2000) Nat. Cell Biol. , vol.2 , pp. 531-539
    • Joberty, G.1    Petersen, C.2    Gao, L.3    MacAra, I.G.4
  • 21
    • 0041969719 scopus 로고    scopus 로고
    • Subcellular localization of LGN during mitosis: Evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression
    • Kaushik R., Yu F., Chia W., Yang X., Bahri S. Subcellular localization of LGN during mitosis. evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression Mol. Biol. Cell. 14:2003;3144-3155
    • (2003) Mol. Biol. Cell , vol.14 , pp. 3144-3155
    • Kaushik, R.1    Yu, F.2    Chia, W.3    Yang, X.4    Bahri, S.5
  • 22
    • 0027481032 scopus 로고
    • The binding site for the β/γ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase
    • Koch W.J., Inglese J., Stone W.C., Lefkowitz R.J. The binding site for the β/γ subunits of heterotrimeric G proteins on the β-adrenergic receptor kinase. J. Biol. Chem. 268:1993;8256-8260
    • (1993) J. Biol. Chem. , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 24
    • 0030298137 scopus 로고    scopus 로고
    • A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly
    • Merdes A., Ramyar K., Vechio J.D., Cleveland D.W. A complex of NuMA and cytoplasmic dynein is essential for mitotic spindle assembly. Cell. 87:1996;447-458
    • (1996) Cell , vol.87 , pp. 447-458
    • Merdes, A.1    Ramyar, K.2    Vechio, J.D.3    Cleveland, D.W.4
  • 25
    • 0037343944 scopus 로고    scopus 로고
    • Visualization of the spatial and temporal dynamics of intracellular signaling
    • Miyawaki A. Visualization of the spatial and temporal dynamics of intracellular signaling. Dev. Cell. 4:2003;295-305
    • (2003) Dev. Cell , vol.4 , pp. 295-305
    • Miyawaki, A.1
  • 26
    • 0036138908 scopus 로고    scopus 로고
    • A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications
    • Nagai T., Ibata K., Park E.S., Kubota M., Mikoshiba K., Miyawaki A. A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications. Nat. Biotechnol. 20:2002;87-90
    • (2002) Nat. Biotechnol. , vol.20 , pp. 87-90
    • Nagai, T.1    Ibata, K.2    Park, E.S.3    Kubota, M.4    Mikoshiba, K.5    Miyawaki, A.6
  • 27
    • 0035340989 scopus 로고    scopus 로고
    • Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs
    • Natochin M., Gasimov K.G., Artemyev N.O. Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs. Biochemistry. 40:2001;5322-5328
    • (2001) Biochemistry , vol.40 , pp. 5322-5328
    • Natochin, M.1    Gasimov, K.G.2    Artemyev, N.O.3
  • 28
    • 0028101021 scopus 로고
    • Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells
    • Reinsch S., Karsenti E. Orientation of spindle axis and distribution of plasma membrane proteins during cell division in polarized MDCKII cells. J. Cell Biol. 126:1994;1509-1526
    • (1994) J. Cell Biol. , vol.126 , pp. 1509-1526
    • Reinsch, S.1    Karsenti, E.2
  • 29
    • 0034611690 scopus 로고    scopus 로고
    • A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila
    • Schaefer M., Shevchenko A., Knöblich J.A. A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila. Curr. Biol. 10:2000;353-362
    • (2000) Curr. Biol. , vol.10 , pp. 353-362
    • Schaefer, M.1    Shevchenko, A.2    Knöblich, J.A.3
  • 30
    • 0035913905 scopus 로고    scopus 로고
    • Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system
    • Schaefer M., Petronczki M., Dorner D., Forte M., Knöblich J.A. Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system. Cell. 107:2001;183-194
    • (2001) Cell , vol.107 , pp. 183-194
    • Schaefer, M.1    Petronczki, M.2    Dorner, D.3    Forte, M.4    Knöblich, J.A.5
  • 31
    • 0346155807 scopus 로고    scopus 로고
    • Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote
    • Schneider S.Q., Bowerman B. Cell polarity and the cytoskeleton in the Caenorhabditis elegans zygote. Annu. Rev. Genet. 37:2003;221-249
    • (2003) Annu. Rev. Genet. , vol.37 , pp. 221-249
    • Schneider, S.Q.1    Bowerman, B.2
  • 32
    • 0037948857 scopus 로고    scopus 로고
    • A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans
    • Srinivasan D.G., Fisk R.M., Xu H., van den Heuvel S. A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans. Genes Dev. 17:2003;1225-1239
    • (2003) Genes Dev. , vol.17 , pp. 1225-1239
    • Srinivasan, D.G.1    Fisk, R.M.2    Xu, H.3    Van Den Heuvel, S.4
  • 33
    • 0030920202 scopus 로고    scopus 로고
    • Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro
    • Vasquez R.J., Howell B., Yvon A.M., Wadsworth P., Cassimeris L. Nanomolar concentrations of nocodazole alter microtubule dynamic instability in vivo and in vitro. Mol. Biol. Cell. 8:1997;973-985
    • (1997) Mol. Biol. Cell , vol.8 , pp. 973-985
    • Vasquez, R.J.1    Howell, B.2    Yvon, A.M.3    Wadsworth, P.4    Cassimeris, L.5
  • 37
    • 0034681261 scopus 로고    scopus 로고
    • Analysis of Partner of Inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in Inscuteable apical localization
    • Yu F., Morin X., Cai Y., Yang X., Chia W. Analysis of Partner of Inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in Inscuteable apical localization. Cell. 100:2000;399-409
    • (2000) Cell , vol.100 , pp. 399-409
    • Yu, F.1    Morin, X.2    Cai, Y.3    Yang, X.4    Chia, W.5
  • 38
    • 0037352776 scopus 로고    scopus 로고
    • A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts
    • Yu F., Morin X., Kaushik R., Bahri S., Yang X., Chia W. A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts. J. Cell Sci. 116:2003;887-896
    • (2003) J. Cell Sci. , vol.116 , pp. 887-896
    • Yu, F.1    Morin, X.2    Kaushik, R.3    Bahri, S.4    Yang, X.5    Chia, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.