Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling

European Journal of Medicinal Chemistry

Volumn 74, Issue , 2014, Pages 95-115

  Rescifina, Antonio ^a   Zagni, Chiara ^a   Varrica, Maria Giulia ^a   Pistarà, Venerando ^a   Corsaro, Antonino ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Anticancer agents; Cancer chemotherapy; DNA intercalators; Docking; Drug discovery; Molecular modeling

Indexed keywords

ACRIDINE DERIVATIVE; ANTINEOPLASTIC AGENT; DNA; DNA B; DNA INTERCALATING AGENT; INDOLE DERIVATIVE; INTERCALATING AGENT; PHENAZINE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; QUINOLINE; QUINOXALINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; BIOLOGICAL ACTIVITY; CANCER CHEMOTHERAPY; CANCER THERAPY; CELL STRAIN HL 60; CHEMICAL STRUCTURE; CONCEPTUAL FRAMEWORK; CRYSTAL STRUCTURE; DNA BINDING; DNA STRUCTURE; DRUG DEVELOPMENT; DRUG SYNTHESIS; HUMAN; INTERCALATION COMPLEX; MOLECULAR MODEL; MOLECULAR RECOGNITION; PROTEIN BINDING; REVIEW;

ANTICANCER AGENTS; CANCER CHEMOTHERAPY; DNA INTERCALATORS; DOCKING; DRUG DISCOVERY; MOLECULAR MODELING;

ANIMALS; CELL LINE, TUMOR; DNA; HUMANS; INTERCALATING AGENTS; MOLECULAR DOCKING SIMULATION;

EID: 84892724604     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.11.029     Document Type: Review

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