DNA binders: 2. Molecular recognition of DNA by 2,3,6,7-tetrahydro-1H- pyrrolo[1,2-a]indole-1,8(5H)-dione bis(4,5-dihydro-1H-imidazol-2-ylhydrazone) as a prototype of "two-armed" intercalating agents

Letters in Drug Design and Discovery

Volumn 6, Issue 4, 2009, Pages 246-251

  Dallocchio, Roberto ^a   Dessì, Alessandro ^a   Sanna, Vanna ^b   Pala, Nicolino ^c   Campesi, Ilaria ^c   Paglietti, Giuseppe ^c   Sechi, Mario ^c  

^a CNR Consiglio Nazionale delle Ricerche   (Italy)

^b Porto Conte Ricerche Srl   (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

Author keywords

2,3,6,7 Tetrahydro 1H pyrrolo 1,2 a indole 1, 8(5H) dione bis(4,5 dihydro 1H imidazol 2 yl hydrazone); DNA binders; Intercalation; Molecular dynamic; Relaxed complex method; Two armed derivatives; Viscosimetry

Indexed keywords

2,3,6,7 TETRAHYDRO 1H PYRROLO[1,2 A]INDOLE 1,8(5H) DIONE BIS(4,5 DIHYDRO 1H IMIDAZOL 2 YL HYDRAZONE); HYDRAZONE DERIVATIVE; INTERCALATING AGENT; LIGAND; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; VISCOMETRY;

EID: 66349101310     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018009788452537     Document Type: Article

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