Design and synthesis of threading intercalators to target DNA

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 23, 2010, Pages 6956-6959

  Howell, Lesley A ^a   Gulam, Rosul ^a   Mueller, Anja ^a   O'Connell, Maria A ^a   Searcey, Mark ^a  

^a UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Acridine; DNA; Intercalator

Indexed keywords

ACID; ACRIDINE DERIVATIVE; AMIDE; DOUBLE STRANDED DNA; INTERCALATING AGENT; PEPTIDE; SULFONIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL NUCLEUS; CELL STRAIN HL 60; CHO CELL; DNA BINDING; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; HUMAN; HUMAN CELL; IC 50; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ACRIDINES; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DNA; DRUG DESIGN; HUMANS; INTERCALATING AGENTS; NUCLEIC ACID CONFORMATION;

EID: 78149359071     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.09.128     Document Type: Article

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