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Bioorganic and Medicinal Chemistry

Volumn 20, Issue 16, 2012, Pages 4978-4984

Synthesis and biological activity of novel bifunctional isoxazolidinyl polycyclic aromatic hydrocarbons

(4) Rescifina, Antonio a Zagni, Chiara a Romeo, Giovanni b Sortino, Salvatore a

a UNIVERSITY OF CATANIA (Italy)

b UNIVERSITY OF MESSINA (Italy)

Author keywords

Anticancer agents; Cation recognition; Cycloaddition; DNA; Docking

Indexed keywords

ANTINEOPLASTIC AGENT; DACTINOMYCIN; DNA; ISOXAZOLIDINYL POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYCLOADDITION; DNA DENATURATION; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG DNA BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROPHORESIS; HUMAN; HUMAN CELL; IC 50; INTERCALATION COMPLEX; MOLECULAR DOCKING; NONHUMAN; PHYSICAL CHEMISTRY; SPECTROFLUOROMETRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; ISOXAZOLES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; POLYCYCLIC HYDROCARBONS, AROMATIC; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 84864422190 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.06.035 Document Type: Article

Times cited : (26)

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