Automating crystallographic structure solution and refinement of protein-ligand complexes

Acta Crystallographica Section D: Biological Crystallography

Volumn 70, Issue 1, 2014, Pages 144-154

  Echols, Nathaniel ^a   Moriarty, Nigel W ^a   Klei, Herbert E ^a   Afonine, Pavel V ^a   Bunkóczi, Gábor ^b   Headd, Jeffrey J ^a   McCoy, Airlie J ^b   Oeffner, Robert D ^b   Read, Randy J ^b   Terwilliger, Thomas C ^c   Adams, Paul D ^a,d  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c LOS ALAMOS NATIONAL LABORATORY   (United States)

^d University of California   (United States)

Author keywords

automation; crystallographic structure solution and refinement; protein ligand complexes

Indexed keywords

BLOOD CLOTTING FACTOR 10A; HUMAN IMMUNODEFICIENCY VIRUS PROTEINASE; LIGAND; P16 PROTEASE, HUMAN IMMUNODEFICIENCY VIRUS 1; PROTEIN; THROMBIN;

ANIMAL; ARTICLE; AUTOMATION; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLOGRAPHIC STRUCTURE SOLUTION AND REFINEMENT; DRUG DESIGN; ENZYMOLOGY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; METHODOLOGY; PROTEIN BINDING; PROTEIN-LIGAND COMPLEXES; X RAY CRYSTALLOGRAPHY;

AUTOMATION; CRYSTALLOGRAPHIC STRUCTURE SOLUTION AND REFINEMENT; PROTEIN-LIGAND COMPLEXES;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; DRUG DESIGN; FACTOR XA; HIV PROTEASE; HIV-1; HUMANS; LIGANDS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEINS; THROMBIN;

EID: 84892413114     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S139900471302748X     Document Type: Article

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