Dynamic roles of arginine residues 82 and 92 of Escherichia coli 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Crystallographic studies

Biochemistry

Volumn 42, Issue 6, 2003, Pages 1573-1580

  Blaszczyk, Jaroslaw ^a   Li, Yue ^b   Shi, Genbin ^b   Yan, Honggao ^b   Ji, Xinhua ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Michigan State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BINDING ENERGY; BIOCHEMISTRY; BIOSYNTHESIS; CONFORMATIONS; CRYSTAL STRUCTURE; ESCHERICHIA COLI; MUTAGENESIS; PHOSPHATES;

LIGANDS;

ENZYME KINETICS;

6 HYDROXYMETHYL 7,8 DIHYDROPTERIN PYROPHOSPHOKINASE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; ARGININE; ENZYME VARIANT; FOLIC ACID; MAGNESIUM ION; MUTANT PROTEIN; PHOSPHATE; PHOSPHOTRANSFERASE; PTERIN DERIVATIVE; PYROPHOSPHORIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOSYNTHESIS; CATALYSIS; CHEMICAL REACTION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; MOLECULAR DYNAMICS; OXIDATION; PRIORITY JOURNAL; STOICHIOMETRY;

ALANINE; ARGININE; BINDING SITES; CATALYSIS; CATIONS, DIVALENT; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHOTRANSFERASES; ESCHERICHIA COLI PROTEINS; MAGNESIUM; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; POINT MUTATION; PROTEIN CONFORMATION; PTERIDINES; PTERINS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0347927707     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0267994     Document Type: Article

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