Three-component domino reaction synthesis of highly functionalized bicyclic pyrrole derivatives

Tetrahedron

Volumn 70, Issue 5, 2014, Pages 1047-1054

  Chen, Xue Bing ^a   Wang, Xiao Ying ^a   Zhu, Dan Dan ^a   Yan, Sheng Jiao ^a   Lin, Jun ^a  

^a YUNNAN UNIVERSITY   (China)

Author keywords

Bicyclic pyrroles; Domino reaction; Heterocyclic ketene aminals; Three component

Indexed keywords

(2 CHLOROPHENYL)[6 (4 FLUOROPHENYL) 7 (1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (2 CHLOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 METHYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (2 CHLOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 PHENYLL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (2 CHLOROPHENYL)[6 PHENYL 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (2 CHLOROPHENYL)[7 (2 METHYL 1H INDOL 3 YL) 6 PHEN YL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (2 FLUOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 METHYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (2 FLUOROPHENYL)[7 (2 METHYL 1H INDOL 3 YL) 6 PHEN YL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 CHLOROPHENYL)[6 (4 FLUOROPHENYL) 7 (1H INDOL 2 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 CHLOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 METHYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 CHLOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 CHLOROPHENYL)[6 PHENYL 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 CHLOROPHENYL)[7 (2 METHYL 1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 CHLOROPHENYL)[7 (4 FLUOROPHENYL) 8 (2 METHYL 1H INDOL 3 YL) 2,3,4,5 TETRAHYDRO 1H PYRROLO[1,2 A][1,3]DIAZEPIN 9 YL]METHANONE; (4 FLUOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 METHYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 FLUOROPHENYL)[6 (4 FLUOROPHENYL) 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 FLUOROPHENYL)[6 PHENYL 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; (4 FLUOROPHENYL)[7 (2 METHYL 1H INDOL 3 YL) 6 PHEN YL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; [6 (4 FLUOROPHENYL) 7 (2 METHYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]PHENYLMETHANONE; [6 (4 FLUOROPHENYL) 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]PHENYLMETHANONE; [7 (1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL](2 CHLOROPHENYL)METHANONE; [7 (1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL](4 CHLOROPHENYL)METHANONE; [7 (1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL](4 FLUOROPHENYL)METHANONE; [7 (1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]PHENYLMETHANONE; [7 (2 METHYL 1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL](PARA TOLYL)METHANONE; [7 (2 METHYL 1H INDOL 3 YL) 6 PHENYL 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]PHENYLMETHANONE; HETEROCYCLIC COMPOUND; INDOLE DERIVATIVE; KETENE DERIVATIVE; PHENYL [6 PHENYL 7 (2 PHENYL 1H INDOL 3 YL) 1,2,3,4 TETRAHYDROPYRROLO[1,2 A]PYRIMIDIN 8 YL]METHANONE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CATALYST; CRYSTAL STRUCTURE; DOMINO REACTION SYNTHESIS; DRUG SCREENING; IN VITRO STUDY; ONE POT SYNTHESIS; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 84892366771     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2013.12.062     Document Type: Article

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