Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach

Journal of Medicinal Chemistry

Volumn 52, Issue 15, 2009, Pages 4941-4945

  Wu, Yu Shan ^a,b   Coumar, Mohane Selvaraj ^a   Chang, Jang Yang ^a   Sun, Hsu Yi ^a   Kuo, Fu Ming ^a   Kuo, Ching Chuan ^a   Chen, Ying Jun ^a   Chang, Chi Yen ^a   Hsiao, Chia Ling ^a   Liou, Jing Ping ^c   Chen, Ching Ping ^a   Yao, Hsien Tsung ^a   Chiang, Yi Kun ^a   Tan, Uan Kang ^d   Chen, Chiung Tong ^a   Chu, Chang Ying ^a   Wu, Su Ying ^a   Yeh, Teng Kuang ^a   Lin, Chin Yu ^a   Hsieh, Hsing Pang ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b TUNGHAI UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TECHNOLOGY AND SCIENCE INSTITUTE OF NORTHERN TAIWAN   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

(7 IODO 6 METHOXY 1H INDOL 3 YL)(3,4,5 TRIMETHOXYPHENYL)METHANONE; 6 METHOXY 3 (3',4',5' TRIMETHOXYBENZOYL) 1H INDOLE; ANTINEOPLASTIC AGENT; BPR 0L075; COLCHICINE; COMBRETASTATIN A4; INDOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BIOTRANSFORMATION; CANCER CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG HALF LIFE; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLITE; MICROSOME; MICROTUBULE ASSEMBLY; MOUSE; NONHUMAN; TUMOR VOLUME; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; COLCHICINE; DRUG DESIGN; HUMANS; INDOLES; MICE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN MODULATORS;

EID: 68549135156     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900060s     Document Type: Article

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