Cripto regulates hematopoietic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78

Cell Stem Cell

Volumn 9, Issue 4, 2011, Pages 330-344

  Miharada, Kenichi ^a   Karlsson, Göran ^a   Rehn, Matilda ^a   Rörby, Emma ^a   Siva, Kavitha ^a   Cammenga, Jörg ^a   Karlsson, Stefan ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIBODY; CELL SURFACE RECEPTOR; GLUCOSE REGULATED PROTEIN 78; GLYCOLYTIC ENZYME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CYTOMETRY; ENDOSCOPE; ENZYME ACTIVITY; FEMALE; HEMATOPOIETIC STEM CELL; HYPOXIC CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELL TRANSPLANTATION;

ANIMALS; BIOLOGICAL MARKERS; BONE AND BONES; CELL HYPOXIA; EPIDERMAL GROWTH FACTOR; GLYCOLYSIS; HEAT-SHOCK PROTEINS; HEMATOPOIETIC STEM CELLS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STEM CELL NICHE; TIME FACTORS; UP-REGULATION;

MUS;

EID: 80053926733     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2011.07.016     Document Type: Article

References (49)

1. F. Arai, A. Hirao, M. Ohmura, H. Sato, S. Matsuoka, K. Takubo, K. Ito, G.Y. Koh, and T. Suda Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche Cell 118 2004 149 161 (Pubitemid 38962572)
2. F. Arai, and T. Suda Maintenance of quiescent hematopoietic stem cells in the osteoblastic niche Ann. N Y Acad. Sci. 1106 2007 41 53 (Pubitemid 47443041)
3. C. Bianco, C. Cotten, E. Lonardo, L. Strizzi, C. Baraty, M. Mancino, M. Gonzales, K. Watanabe, T. Nagaoka, and C. Berry Cripto-1 is required for hypoxia to induce cardiac differentiation of mouse embryonic stem cells Am. J. Pathol. 175 2009 2146 2158
4. C. Bianco, M.C. Rangel, N.P. Castro, T. Nagaoka, K. Rollman, M. Gonzales, and D.S. Salomon Role of Cripto-1 in stem cell maintenance and malignant progression Am. J. Pathol. 177 2010 532 540
5. G.A. Challen, N.C. Boles, S.M. Chambers, and M.A. Goodell Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-β1 Cell Stem Cell 6 2010 265 278
6. A. Ciccodicola, R. Dono, S. Obici, A. Simeone, M. Zollo, and M.G. Persico Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells EMBO J. 8 1989 1987 1991 (Pubitemid 19273525)
7. G.H. Danet, Y. Pan, J.L. Luongo, D.A. Bonnet, and M.C. Simon Expansion of human SCID-repopulating cells under hypoxic conditions J. Clin. Invest. 112 2003 126 135 (Pubitemid 38056384)
8. D.J. Davidson, C. Haskell, S. Majest, A. Kherzai, D.A. Egan, K.A. Walter, A. Schneider, E.F. Gubbins, L. Solomon, and Z. Chen Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78 Cancer Res. 65 2005 4663 4672 (Pubitemid 40740802)
9. J. Ding, L. Yang, Y.T. Yan, A. Chen, N. Desai, A. Wynshaw-Boris, and M.M. Shen Cripto is required for correct orientation of the anterior-posterior axis in the mouse embryo Nature 395 1998 702 707 (Pubitemid 28475967)
10. B. Dykstra, D. Kent, M. Bowie, L. McCaffrey, M. Hamilton, K. Lyons, S.J. Lee, R. Brinkman, and C. Eaves Long-term propagation of distinct hematopoietic differentiation programs in vivo Cell Stem Cell 1 2007 218 229 (Pubitemid 47215588)
11. M. Gonzalez-Gronow, M.A. Selim, J. Papalas, and S.V. Pizzo GRP78: a multifunctional receptor on the cell surface Antioxid. Redox Signal. 11 2009 2299 2306
12. M.A. Goodell, K. Brose, G. Paradis, A.S. Conner, and R.C. Mulligan Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo J. Exp. Med. 183 1996 1797 1806 (Pubitemid 26134320)
13. J. Grassinger, D.N. Haylock, B. Williams, G.H. Olsen, and S.K. Nilsson Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential Blood 116 2010 3185 3196
14. P.C. Gray, G. Shani, K. Aung, J. Kelber, and W. Vale Cripto binds transforming growth factor β (TGF-β) and inhibits TGF-β signaling Mol. Cell. Biol. 26 2006 9268 9278 (Pubitemid 44904422)
15. B. Hardy, and A. Raiter Peptide-binding heat shock protein GRP78 protects cardiomyocytes from hypoxia-induced apoptosis J. Mol. Med. 88 2010 1157 1167
16. J.S. Haug, X.C. He, J.C. Grindley, J.P. Wunderlich, K. Gaudenz, J.T. Ross, A. Paulson, K.P. Wagner, Y. Xie, and R. Zhu N-cadherin expression level distinguishes reserved versus primed states of hematopoietic stem cells Cell Stem Cell 2 2008 367 379 (Pubitemid 351455240)
17. S.R. Hough, A.L. Laslett, S.B. Grimmond, G. Kolle, and M.F. Pera A continuum of cell states spans pluripotency and lineage commitment in human embryonic stem cells PLoS ONE 4 2009 e7708
18. Y. Huang, and J.K. Burkhardt T-cell-receptor-dependent actin regulatory mechanisms J. Cell Sci. 120 2007 723 730 (Pubitemid 46523474)
19. J. Kahn, T. Byk, L. Jansson-Sjostrand, I. Petit, S. Shivtiel, A. Nagler, I. Hardan, V. Deutsch, Z. Gazit, and D. Gazit Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulation Blood 103 2004 2942 2949 (Pubitemid 38451665)
20. G. Karlsson, U. Blank, J.L. Moody, M. Ehinger, S. Singbrant, C.X. Deng, and S. Karlsson Smad4 is critical for self-renewal of hematopoietic stem cells J. Exp. Med. 204 2007 467 474 (Pubitemid 46457070)
21. B. Keith, and M.C. Simon Hypoxia-inducible factors, stem cells, and cancer Cell 129 2007 465 472 (Pubitemid 46660978)
22. J.A. Kelber, A.D. Panopoulos, G. Shani, E.C. Booker, J.C. Belmonte, W.W. Vale, and P.C. Gray Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways Oncogene 28 2009 2324 2336
23. D.G. Kent, M.R. Copley, C. Benz, S. Wöhrer, B.J. Dykstra, E. Ma, J. Cheyne, Y. Zhao, M.B. Bowie, and Y. Zhao Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential Blood 113 2009 6342 6350
24. M.J. Kiel, and S.J. Morrison Uncertainty in the niches that maintain haematopoietic stem cells Nat. Rev. Immunol. 8 2008 290 301 (Pubitemid 351432804)
25. M.J. Kiel, O.H. Yilmaz, T. Iwashita, O.H. Yilmaz, C. Terhorst, and S.J. Morrison SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells Cell 121 2005 1109 1121 (Pubitemid 40884400)
26. Y. Kubota, K. Takubo, and T. Suda Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche Biochem. Biophys. Res. Commun. 366 2008 335 339 (Pubitemid 50016265)
27. L. Li, and H. Clevers Coexistence of quiescent and active adult stem cells in mammals Science 327 2010 542 545
28. C.L. Li, and G.R. Johnson Murine hematopoietic stem and progenitor cells: I. Enrichment and biologic characterization Blood 85 1995 1472 1479
29. S. Malhotra, and P.W. Kincade Wnt-related molecules and signaling pathway equilibrium in hematopoiesis Cell Stem Cell 4 2009 27 36
30. Y. Morita, H. Ema, and H. Nakauchi Heterogeneity and hierarchy within the most primitive hematopoietic stem cell compartment J. Exp. Med. 207 2010 1173 1182
31. S.J. Morrison, and A.C. Spradling Stem cells and niches: mechanisms that promote stem cell maintenance throughout life Cell 132 2008 598 611 (Pubitemid 351253690)
32. Y. Nakamura, F. Arai, H. Iwasaki, K. Hosokawa, I. Kobayashi, Y. Gomei, Y. Matsumoto, H. Yoshihara, and T. Suda Isolation and characterization of endosteal niche cell populations that regulate hematopoietic stem cells Blood 116 2010 1422 1432
33. T. Ogaeri, K. Eto, M. Otsu, H. Ema, and H. Nakauchi The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells Stem Cells 27 2009 1120 1129
34. M. Osawa, K. Hanada, H. Hamada, and H. Nakauchi Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell Science 273 1996 242 245 (Pubitemid 26285891)
35. L. Østergaard, U. Simonsen, Y. Eskildsen-Helmond, H. Vorum, N. Uldbjerg, B. Honoré, and M.J. Mulvany Proteomics reveals lowering oxygen alters cytoskeletal and endoplasmatic stress proteins in human endothelial cells Proteomics 9 2009 4457 4467
36. K. Parmar, P. Mauch, J.A. Vergilio, R. Sackstein, and J.D. Down Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia Proc. Natl. Acad. Sci. USA 104 2007 5431 5436 (Pubitemid 47175697)
37. P. Pinto do Ó, K. Richter, and L. Carlsson Hematopoietic progenitor/stem cells immortalized by Lhx2 generate functional hematopoietic cells in vivo Blood 99 2002 3939 3946 (Pubitemid 35332032)
38. D.S. Saloman, C. Bianco, A.D. Ebert, N.I. Khan, M. De Santis, N. Normanno, C. Wechselberger, M. Seno, K. Williams, and M. Sanicola The EGF-CFC family: novel epidermal growth factor-related proteins in development and cancer Endocr. Relat. Cancer 7 2000 199 226 (Pubitemid 32172272)
39. N. Sato, I.M. Sanjuan, M. Heke, M. Uchida, F. Naef, and A.H. Brivanlou Molecular signature of human embryonic stem cells and its comparison with the mouse Dev. Biol. 260 2003 404 413 (Pubitemid 36960088)
40. D.T. Scadden The stem-cell niche as an entity of action Nature 441 2006 1075 1079 (Pubitemid 43990719)
41. T. Schroeder Hematopoietic stem cell heterogeneity: subtypes, not unpredictable behavior Cell Stem Cell 6 2010 203 207
42. G. Shani, W.H. Fischer, N.J. Justice, J.A. Kelber, W. Vale, and P.C. Gray GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor β signaling and enhance cell growth Mol. Cell. Biol. 28 2008 666 677
43. T. Simsek, F. Kocabas, J. Zheng, R.J. Deberardinis, A.I. Mahmoud, E.N. Olson, J.W. Schneider, C.C. Zhang, and H.A. Sadek The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche Cell Stem Cell 7 2010 380 390
44. L. Strizzi, C. Bianco, N. Normanno, and D. Salomon Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis Oncogene 24 2005 5731 5741 (Pubitemid 43086133)
45. K. Takubo, N. Goda, W. Yamada, H. Iriuchishima, E. Ikeda, Y. Kubota, H. Shima, R.S. Johnson, A. Hirao, M. Suematsu, and T. Suda Regulation of the HIF-1α level is essential for hematopoietic stem cells Cell Stem Cell 7 2010 391 402
46. A. Wilson, E. Laurenti, G. Oser, R.C. van der Wath, W. Blanco-Bose, M. Jaworski, S. Offner, C.F. Dunant, L. Eshkind, and E. Bockamp Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair Cell 135 2008 1118 1129
47. C. Xu, G. Liguori, E.D. Adamson, and M.G. Persico Specific arrest of cardiogenesis in cultured embryonic stem cells lacking Cripto-1 Dev. Biol. 196 1998 237 247 (Pubitemid 28198850)
48. S. Yamazaki, A. Iwama, S. Takayanagi, K. Eto, H. Ema, and H. Nakauchi TGF-β as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation Blood 113 2009 1250 1256
49. J. Zhou, T. Schmid, R. Frank, and B. Brüne PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1α from pVHL-independent degradation J. Biol. Chem. 279 2004 13506 13513 (Pubitemid 38468875)