-
1
-
-
0030034673
-
Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias
-
DOI 10.1038/ng0296-149
-
Nakamura T, Largaespada DA, Shaughnessy JD Jr, Jenkins NA, Copeland NG. Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukaemias. Nat Genet. 1996;12(2):149-153. (Pubitemid 26051294)
-
(1996)
Nature Genetics
, vol.12
, Issue.2
, pp. 149-153
-
-
Nakamura, T.1
Largaespada, D.A.2
Shaughnessy Jr., J.D.3
Jenkins, N.A.4
Copeland, N.G.5
-
2
-
-
0034747741
-
Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia
-
Thorsteinsdottir U, Kroon E, Jerome L, Blasi F, Sauvageau G. Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia. Mol Cell Biol. 2001;21(1):224-234.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.1
, pp. 224-234
-
-
Thorsteinsdottir, U.1
Kroon, E.2
Jerome, L.3
Blasi, F.4
Sauvageau, G.5
-
3
-
-
0036142691
-
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny
-
DOI 10.1016/S0301-472X(01)00757-3, PII S0301472X01007573
-
Pineault N, Helgason CD, Lawrence HJ, Humphries RK. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol. 2002;30(1):49-57. (Pubitemid 34059217)
-
(2002)
Experimental Hematology
, vol.30
, Issue.1
, pp. 49-57
-
-
Pineault, N.1
Helgason, C.D.2
Lawrence, H.J.3
Humphries, R.K.4
-
4
-
-
42949097515
-
Malignant Transformation Initiated by Mll-AF9: Gene Dosage and Critical Target Cells
-
DOI 10.1016/j.ccr.2008.03.005, PII S1535610808000901
-
Chen W, Kumar AR, Hudson WA, et al. Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells. Cancer Cell. 2008;13(5):432-440. (Pubitemid 351609442)
-
(2008)
Cancer Cell
, vol.13
, Issue.5
, pp. 432-440
-
-
Chen, W.1
Kumar, A.R.2
Hudson, W.A.3
Li, Q.4
Wu, B.5
Staggs, R.A.6
Lund, E.A.7
Sam, T.N.8
Kersey, J.H.9
-
5
-
-
18844434679
-
The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo
-
DOI 10.1016/j.ydbio.2005.01.004, PII S0012160605000059
-
Azcoitia V, Aracil M, Martinez AC, Torres M. The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. Dev Biol. 2005;280(2):307-320. (Pubitemid 40692134)
-
(2005)
Developmental Biology
, vol.280
, Issue.2
, pp. 307-320
-
-
Azcoitia, V.1
Aracil, M.2
Martinez-A, C.3
Torres, M.4
-
6
-
-
10744229578
-
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
-
DOI 10.1038/sj.emboj.7600038
-
Hisa T, Spence SE, Rachel RA, et al. Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J. 2004;23(2):450-459. (Pubitemid 38294509)
-
(2004)
EMBO Journal
, vol.23
, Issue.2
, pp. 450-459
-
-
Hisa, T.1
Spence, S.E.2
Rachel, R.A.3
Fujita, M.4
Nakamura, T.5
Ward, J.M.6
Devor-Henneman, D.E.7
Saiki, Y.8
Kutsuna, H.9
Tessarollo, L.10
Jenkins, N.A.11
Copeland, N.G.12
-
7
-
-
0030813558
-
Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins
-
Chang C, Jacobs Y, Nakamura T, Jenkins N, Copeland N, Cleary M. Meis proteins are major in vivo DNA binding partners for wild-type but not chimeric Pbx proteins. Mol Cell Biol. 1997;17(10):5679-5687. (Pubitemid 27411075)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.10
, pp. 5679-5687
-
-
Chang, C.-P.1
Jacobs, Y.2
Nakamura, T.3
Jenkins, N.A.4
Copeland, N.G.5
Cleary, M.L.6
-
8
-
-
0032964378
-
HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells
-
Shen W-F, Rozenfeld S, Kwong A, Komuves LG, Lawrence HJ, Largman C. HOXA9 Forms Triple Complexes with PBX2 and MEIS1 in Myeloid Cells. Mol Cell Biol. 1999;19(4):3051-3061. (Pubitemid 29144550)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.4
, pp. 3051-3061
-
-
Shen, W.-F.1
Rozenfeld, S.2
Kwong, A.3
Komuves, L.G.4
Lawrence, H.J.5
Largman, C.6
-
9
-
-
42649142267
-
Pbx1 Regulates Self-Renewal of Long-Term Hematopoietic Stem Cells by Maintaining Their Quiescence
-
DOI 10.1016/j.stem.2008.03.004, PII S1934590908001161
-
Ficara F, Murphy MJ, Lin M, Cleary ML. Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence. Cell Stem Cell. 2008;2(5):484-496. (Pubitemid 351598079)
-
(2008)
Cell Stem Cell
, vol.2
, Issue.5
, pp. 484-496
-
-
Ficara, F.1
Murphy, M.J.2
Lin, M.3
Cleary, M.L.4
-
10
-
-
79960989834
-
Stem cell quiescence
-
Li L, Bhatia R. Stem cell quiescence. Clin Cancer Res. 2011;17(15):4936-4941.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.15
, pp. 4936-4941
-
-
Li, L.1
Bhatia, R.2
-
11
-
-
77956217067
-
Regulation of the HIF-1alpha level is essential for hematopoietic stem cells
-
Takubo K, Goda N, Yamada W, et al. Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell. 2010;7(3):391-402.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.3
, pp. 391-402
-
-
Takubo, K.1
Goda, N.2
Yamada, W.3
-
12
-
-
77956205122
-
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
-
Simsek T, Kocabas F, Zheng J, et al. The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell. 2010;7(3):380-390.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.3
, pp. 380-390
-
-
Simsek, T.1
Kocabas, F.2
Zheng, J.3
-
14
-
-
0037352031
-
A highly efficient recombineering-based method for generating conditional knockout mutations
-
DOI 10.1101/gr.749203
-
Liu P, Jenkins NA, Copeland NG. A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout Mutations. Genome Research. 2003;13(3):476-484. (Pubitemid 36395405)
-
(2003)
Genome Research
, vol.13
, Issue.3
, pp. 476-484
-
-
Liu, P.1
Jenkins, N.A.2
Copeland, N.G.3
-
15
-
-
65549095150
-
Manipulating mouse embryonic stem cells
-
Southon E, Tessarollo L. Manipulating mouse embryonic stem cells. Methods Mol Biol. 2009;530:165-185.
-
(2009)
Methods Mol Biol
, vol.530
, pp. 165-185
-
-
Southon, E.1
Tessarollo, L.2
-
16
-
-
65549094170
-
Isolation, microinjection and transfer of mouse blastocysts
-
Reid SW, Tessarollo L. Isolation, microinjection and transfer of mouse blastocysts. Methods Mol Biol. 2009;530:269-285.
-
(2009)
Methods Mol Biol
, vol.530
, pp. 269-285
-
-
Reid, S.W.1
Tessarollo, L.2
-
17
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
DOI 10.1038/nature05541, PII NATURE05541
-
Ventura A, Kirsch DG, McLaughlin ME, et al. Restoration of p53 function leads to tumour regression in vivo. Nature. 2007;445(7128):661-665. (Pubitemid 46232887)
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
-
18
-
-
84855432325
-
Conditional hypoxia inducible factor-1alpha induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis
-
Bridges JP, Lin S, Ikegami M, Shannon JM. Conditional hypoxia inducible factor-1alpha induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol. 2012;362(1):24-41.
-
(2012)
Dev Biol
, vol.362
, Issue.1
, pp. 24-41
-
-
Bridges, J.P.1
Lin, S.2
Ikegami, M.3
Shannon, J.M.4
-
19
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med. 2006;12(4):446-451.
-
(2006)
Nat Med
, vol.12
, Issue.4
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
-
20
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
DOI 10.1073/pnas.0506580102
-
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005;102(43):15545-15550. (Pubitemid 41528093)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
Paulovich, A.7
Pomeroy, S.L.8
Golub, T.R.9
Lander, E.S.10
Mesirov, J.P.11
-
21
-
-
1442356858
-
Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia
-
DOI 10.1182/blood-2003-07-2582
-
Kumar AR, Hudson WA, Chen W, Nishiuchi R, Yao Q, Kersey JH. Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia. Blood. 2004;103(5):1823-1828. (Pubitemid 38268979)
-
(2004)
Blood
, vol.103
, Issue.5
, pp. 1823-1828
-
-
Kumar, A.R.1
Hudson, W.A.2
Chen, W.3
Nishiuchi, R.4
Yao, Q.5
Kersey, J.H.6
-
22
-
-
28444446313
-
Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): Association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance
-
DOI 10.1182/blood-2005-05-2168
-
Verhaak RG, Goudswaard CS, van Putten W, et al. Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance. Blood. 2005;106(12):3747-3754. (Pubitemid 41739008)
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3747-3754
-
-
Verhaak, R.G.W.1
Goudswaard, C.S.2
Van Putten, W.3
Bijl, M.A.4
Sanders, M.A.5
Hugens, W.6
Uitterlinden, A.G.7
Erpelinck, C.A.J.8
Delwel, R.9
Lowenberg, B.10
Valk, P.J.M.11
-
23
-
-
11244315697
-
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
-
DOI 10.1182/blood-2004-07-2958
-
Manalo DJ, Rowan A, Lavoie T, et al. Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1. Blood. 2005;105(2):659-669. (Pubitemid 40070750)
-
(2005)
Blood
, vol.105
, Issue.2
, pp. 659-669
-
-
Manalo, D.J.1
Rowan, A.2
Lavoie, T.3
Natarajan, L.4
Kelly, B.D.5
Ye, S.Q.6
Garcia, J.G.N.7
Semenza, G.L.8
-
24
-
-
33646765735
-
Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes
-
DOI 10.1152/physiolgenomics.00315.2005
-
Mense SM, Sengupta A, Zhou M, et al. Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes. Physiol Genomics. 2006;25(3):435-449. (Pubitemid 43764765)
-
(2006)
Physiological Genomics
, vol.25
, Issue.3
, pp. 435-449
-
-
Mense, S.M.1
Sengupta, A.2
Zhou, M.3
Lan, C.4
Bentsman, G.5
Volsky, D.J.6
Zhang, L.7
-
26
-
-
34548457683
-
Effect of chemical stabilizers of hypoxia-inducible factors on early lung development
-
DOI 10.1152/ajplung.00486.2006
-
Groenman FA, Rutter M, Wang J, Caniggia I, Tibboel D, Post M. Effect of chemical stabilizers of hypoxia-inducible factors on early lung development. Am J Physiol Lung Cell Mol Physiol. 2007;293(3):L557-L567. (Pubitemid 47358816)
-
(2007)
American Journal of Physiology - Lung Cellular and Molecular Physiology
, vol.293
, Issue.3
-
-
Groenman, F.A.1
Rutter, M.2
Wang, J.3
Caniggia, I.4
Tibboel, D.5
Post, M.6
-
27
-
-
60149100010
-
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter
-
Chen MJ, Yokomizo T, Zeigler BM, Dzierzak E, Speck NA. Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature. 2009;457(7231):887-891.
-
(2009)
Nature
, vol.457
, Issue.7231
, pp. 887-891
-
-
Chen, M.J.1
Yokomizo, T.2
Zeigler, B.M.3
Dzierzak, E.4
Speck, N.A.5
-
28
-
-
3242669145
-
Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
-
DOI 10.1016/j.cell.2004.07.004, PII S0092867404006622
-
Arai F, Hirao A, Ohmura M, et al. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche. Cell. 2004;118(2):149-161. (Pubitemid 38962572)
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 149-161
-
-
Arai, F.1
Hirao, A.2
Ohmura, M.3
Sato, H.4
Matsuoka, S.5
Takubo, K.6
Ito, K.7
Koh, G.Y.8
Suda, T.9
-
29
-
-
79551649810
-
The role of meis1 in primitive and definitive hematopoiesis during zebrafish development
-
Cvejic A, Serbanovic-Canic J, Stemple DL, Ouwehand WH. The role of meis1 in primitive and definitive hematopoiesis during zebrafish development. Haematologica. 2011;96(2):190-198.
-
(2011)
Haematologica
, vol.96
, Issue.2
, pp. 190-198
-
-
Cvejic, A.1
Serbanovic-Canic, J.2
Stemple, D.L.3
Ouwehand, W.H.4
-
30
-
-
79955974326
-
Prdm16 is a physiologic regulator of hematopoietic stem cells
-
Aguilo F, Avagyan S, Labar A, et al. Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood. 2011;117(19):5057-5066.
-
(2011)
Blood
, vol.117
, Issue.19
, pp. 5057-5066
-
-
Aguilo, F.1
Avagyan, S.2
Labar, A.3
-
31
-
-
73949121249
-
The hematopoietic stem cell niche: Low in oxygen but a nice place to be
-
Eliasson P, Jonsson JI. The hematopoietic stem cell niche: low in oxygen but a nice place to be. J Cell Physiol. 2010;222(1):17-22.
-
(2010)
J Cell Physiol
, vol.222
, Issue.1
, pp. 17-22
-
-
Eliasson, P.1
Jonsson, J.I.2
-
32
-
-
78349272461
-
HIF-1 and HIF-2 transcription factors-similar but not identical
-
Loboda A, Jozkowicz A, Dulak J. HIF-1 and HIF-2 transcription factors-similar but not identical. Mol Cells. 2010;29(5):435-442.
-
(2010)
Mol Cells
, vol.29
, Issue.5
, pp. 435-442
-
-
Loboda, A.1
Jozkowicz, A.2
Dulak, J.3
-
33
-
-
17044378251
-
HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner
-
Scortegagna M, Ding K, Zhang Q, et al. HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner. Blood. 2005;105(8):3133-3140.
-
(2005)
Blood
, vol.105
, Issue.8
, pp. 3133-3140
-
-
Scortegagna, M.1
Ding, K.2
Zhang, Q.3
-
34
-
-
15444342958
-
2 homeostasis by hypoxia- inducible factor 1alpha
-
Iyer NV, Kotch LE, Agani F, et al. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes Dev. 1998;12(2):149-162. (Pubitemid 28060446)
-
(1998)
Genes and Development
, vol.12
, Issue.2
, pp. 149-162
-
-
Iyer, N.V.1
Kotch, L.E.2
Agani, F.3
Leung, S.W.4
Laughner, E.5
Wenger, R.H.6
Gassmann, M.7
Gearhart, J.D.8
Lawler, A.M.9
Yu, A.Y.10
Semenza, G.L.11
-
35
-
-
0032100732
-
HIF-1alpha is required for solid tumor formation and embryonic vascularization
-
DOI 10.1093/emboj/17.11.3005
-
Ryan HE, Lo J, Johnson RS. HIF-1 alpha is required for solid tumor formation and embryonic vascularization. EMBO J. 1998;17(11):3005-3015. (Pubitemid 28254373)
-
(1998)
EMBO Journal
, vol.17
, Issue.11
, pp. 3005-3015
-
-
Ryan, H.E.1
Lo, J.2
Johnson, R.S.3
|