Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

Nature Genetics

Volumn 29, Issue 4, 2001, Pages 469-474

  Bamforth, Simon D ^a   Bragança, José ^a   Eloranta, Jyrki J ^b   Murdoch, Jennifer N ^c   Marques, Fatima I R ^a   Kranc, Kamil R ^a   Farza, Hend ^a   Henderson, Deborah J ^c   Hurst, Helen C ^b   Bhattacharya, Shoumo ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; E1A ASSOCIATED P300 PROTEIN; GENE PRODUCT; PROTEIN CITED2; TRANSCRIPTION FACTOR AP 2; UNCLASSIFIED DRUG;

ADRENAL GLAND MALFORMATION; AGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ARCH ANOMALY; AORTA DISEASE; APOPTOSIS; ARTICLE; CONGENITAL HEART MALFORMATION; EMBRYO; EMBRYO DEVELOPMENT; EXENCEPHALY; HEART ATRIUM SEPTUM DEFECT; HEART DEVELOPMENT; HEART RIGHT VENTRICLE DOUBLE OUTLET; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HUMAN CELL; MESENCEPHALON; MOUSE; NEURAL CREST; NEURAL TUBE; NONHUMAN; PATENT DUCTUS ARTERIOSUS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ADRENAL GLANDS; ANIMALS; CELL LINE; DNA-BINDING PROTEINS; FEMALE; HEART DEFECTS, CONGENITAL; MALE; MICE; MICE, KNOCKOUT; NEURAL CREST; NEURAL TUBE DEFECTS; REPRESSOR PROTEINS; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 18344389337     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng768     Document Type: Article

References (30)

1. CBP/p300 in cell growth, transformation, and development
2. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
3. Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis
4. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
5. Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: Implications for a dominant-negative mechanism
6. Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
7. Cardiac abnormalities in the Rubinstein-Taybi syndrome
8. Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1
9. MSG1 and its related protein MRG1 share a transcription activating domain
10. MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone α-subunit gene expression
11. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2
12. Transcription factor AP-2 essential for cranial closure and craniofacial development
13. Mutations in TFAP2B cause Char syndrome, a familial form of patent ductus arteriosus
14. The role of cell death in regulating the size and shape of the mammalian forebrain
15. Multiple essential functions of neuregulin in development
16. The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system
17. Severe neuropathies in mice with targeted mutations in the ErbB3 receptor
18. ErbB3 is required for normal cerebellar and cardiac development: A comparison with ErbB2- and heregulin-deficient mice
19. Mouse models for neural tube closure defects
20. Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis
21. Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis
22. Comparative analysis of AP-2α and AP-2β gene expression during murine embryogenesis
23. Transcriptional regulation of the c-erbB-3 gene in human breast carcinoma cell lines
24. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
25. −/− embryos is associated with failure to close the neural tube
26. Whole mount in situ hybridization of vertebrate embryos
27. A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma
28. Primary and multipassage culture of mouse embryo cells in serum-containing and serum-free media