-
1
-
-
0032797852
-
Regulation of glucose production by the liver
-
Nordlie, R. C., Foster, J. D. and Lange, A. J. (1999) Regulation of glucose production by the liver. Annu. Rev. Nutr. 19, 379-406.
-
(1999)
Annu. Rev. Nutr.
, vol.19
, pp. 379-406
-
-
Nordlie, R.C.1
Foster, J.D.2
Lange, A.J.3
-
2
-
-
0023918674
-
Hormonal regulation of hepatic gluconeogenesis and glycolysis
-
Pilkis, S. J., el-Maghrabi, M. R. and Claus, T. H. (1988) Hormonal regulation of hepatic gluconeogenesis and glycolysis. Annu. Rev. Biochem. 57, 755-783.
-
(1988)
Annu. Rev. Biochem.
, vol.57
, pp. 755-783
-
-
Pilkis, S.J.1
el-Maghrabi, M.R.2
Claus, T.H.3
-
3
-
-
0025914685
-
Hepatic gluconeogenesis/ glycolysis: regulation and structure/function relationships of substrate cycle enzymes
-
Pilkis, S. J. and Claus, T. H. (1991) Hepatic gluconeogenesis/ glycolysis: regulation and structure/function relationships of substrate cycle enzymes. Annu. Rev. Nutr. 11, 465-515.
-
(1991)
Annu. Rev. Nutr.
, vol.11
, pp. 465-515
-
-
Pilkis, S.J.1
Claus, T.H.2
-
4
-
-
0030753971
-
Regulation of the expression of lipogenic enzyme genes by carbohydrate
-
Towle, H. C., Kaytor, E. N. and Shih, H. M. (1997) Regulation of the expression of lipogenic enzyme genes by carbohydrate. Annu. Rev. Nutr. 17, 405-433.
-
(1997)
Annu. Rev. Nutr.
, vol.17
, pp. 405-433
-
-
Towle, H.C.1
Kaytor, E.N.2
Shih, H.M.3
-
5
-
-
38649116056
-
Selective versus total insulin resistance: a pathogenic paradox
-
Brown, M. S. and Goldstein, J. L. (2008) Selective versus total insulin resistance: a pathogenic paradox. Cell Metab. 7, 95-96.
-
(2008)
Cell Metab.
, vol.7
, pp. 95-96
-
-
Brown, M.S.1
Goldstein, J.L.2
-
6
-
-
38449087713
-
ChREBP, a transcriptional regulator of glucose and lipid metabolism
-
Postic, C., Dentin, R., Denechaud, P. D. and Girard, J. (2007) ChREBP, a transcriptional regulator of glucose and lipid metabolism. Annu. Rev. Nutr. 27, 179-192.
-
(2007)
Annu. Rev. Nutr.
, vol.27
, pp. 179-192
-
-
Postic, C.1
Dentin, R.2
Denechaud, P.D.3
Girard, J.4
-
7
-
-
33746536677
-
Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis
-
Uyeda, K. and Repa, J. J. (2006) Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. Cell Metab. 4, 107-110.
-
(2006)
Cell Metab.
, vol.4
, pp. 107-110
-
-
Uyeda, K.1
Repa, J.J.2
-
8
-
-
0031957026
-
Autoregulation of hepatic glucose production
-
Moore, M. C., Connolly, C. C. and Cherrington, A. D. (1998) Autoregulation of hepatic glucose production. Eur. J. Endocrinol. 138, 240-248.
-
(1998)
Eur. J. Endocrinol.
, vol.138
, pp. 240-248
-
-
Moore, M.C.1
Connolly, C.C.2
Cherrington, A.D.3
-
9
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel, A. R. and Kahn, C. R. (2001) Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414, 799-806.
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
10
-
-
0035855905
-
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
-
Herzig, S., Long, F., Jhala, U. S., Hedrick, S., Quinn, R., Bauer, A., Rudolph, D., Schutz, G., Yoon, C., Puigserver, P., Spiegelman, B. and Montminy, M. (2001) CREB regulates hepatic gluconeogenesis through the coactivator PGC-1. Nature 413, 179-183.
-
(2001)
Nature
, vol.413
, pp. 179-183
-
-
Herzig, S.1
Long, F.2
Jhala, U.S.3
Hedrick, S.4
Quinn, R.5
Bauer, A.6
Rudolph, D.7
Schutz, G.8
Yoon, C.9
Puigserver, P.10
Spiegelman, B.11
Montminy, M.12
-
11
-
-
84862653969
-
Orphan nuclear receptor es trogen-related receptor gamma (ERRgamma) is key regulator of hepatic gluconeogenesis
-
Kim, D. K., Ryu, D., Koh, M., Lee, M. W., Lim, D., Kim, M. J., Kim, Y. H., Cho, W. J., Lee, C. H., Park, S. B., Koo, S. H. and Choi, H. S. (2012) Orphan nuclear receptor es trogen-related receptor gamma (ERRgamma) is key regulator of hepatic gluconeogenesis. J. Biol. Chem. 287, 21628-21639.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 21628-21639
-
-
Kim, D.K.1
Ryu, D.2
Koh, M.3
Lee, M.W.4
Lim, D.5
Kim, M.J.6
Kim, Y.H.7
Cho, W.J.8
Lee, C.H.9
Park, S.B.10
Koo, S.H.11
Choi, H.S.12
-
12
-
-
77950285163
-
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH
-
Lee, M. W., Chanda, D., Yang, J., Oh, H., Kim, S. S., Yoon, Y. S., Hong, S., Park, K. G., Lee, I. K., Choi, C. S., Hanson, R. W., Choi, H. S. and Koo, S. H. (2010) Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH. Cell Metab. 11, 331-339.
-
(2010)
Cell Metab.
, vol.11
, pp. 331-339
-
-
Lee, M.W.1
Chanda, D.2
Yang, J.3
Oh, H.4
Kim, S.S.5
Yoon, Y.S.6
Hong, S.7
Park, K.G.8
Lee, I.K.9
Choi, C.S.10
Hanson, R.W.11
Choi, H.S.12
Koo, S.H.13
-
13
-
-
0037086660
-
The glucose-6- phosphatase system
-
van Schaftingen, E. and Gerin, I. (2002) The glucose-6- phosphatase system. Biochem. J. 362, 513-532.
-
(2002)
Biochem. J.
, vol.362
, pp. 513-532
-
-
van Schaftingen, E.1
Gerin, I.2
-
14
-
-
79960938560
-
Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control
-
Bedford, D. C., Kasper, L. H., Wang, R., Chang, Y., Green, D. R. and Brindle, P. K. (2011) Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control. Cell Metab. 14, 219-230.
-
(2011)
Cell Metab.
, vol.14
, pp. 219-230
-
-
Bedford, D.C.1
Kasper, L.H.2
Wang, R.3
Chang, Y.4
Green, D.R.5
Brindle, P.K.6
-
15
-
-
84867169367
-
Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner
-
Choi, D., Oh, K. J., Han, H. S., Yoon, Y. S., Jung, C. Y., Kim, S. T. and Koo, S. H. (2012) Protein arginine methyltransferase 1 regulates hepatic glucose production in a FoxO1-dependent manner. Hepatology. 56, 1546-1556.
-
(2012)
Hepatology.
, vol.56
, pp. 1546-1556
-
-
Choi, D.1
Oh, K.J.2
Han, H.S.3
Yoon, Y.S.4
Jung, C.Y.5
Kim, S.T.6
Koo, S.H.7
-
16
-
-
27144506185
-
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism
-
Koo, S. H., Flechner, L., Qi, L., Zhang, X., Screaton, R. A., Jeffries, S., Hedrick, S., Xu, W., Boussouar, F., Brindle, P., Takemori, H. and Montminy, M. (2005) The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism. Nature 437, 1109-1111.
-
(2005)
Nature
, vol.437
, pp. 1109-1111
-
-
Koo, S.H.1
Flechner, L.2
Qi, L.3
Zhang, X.4
Screaton, R.A.5
Jeffries, S.6
Hedrick, S.7
Xu, W.8
Boussouar, F.9
Brindle, P.10
Takemori, H.11
Montminy, M.12
-
17
-
-
33645649005
-
Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1
-
Krones-Herzig, A., Mesaros, A., Metzger, D., Ziegler, A., Lemke, U., Bruning, J. C. and Herzig, S. (2006) Signal-dependent control of gluconeogenic key enzyme genes through coactivator-associated arginine methyltransferase 1. J. Biol. Chem. 281, 3025-3029.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 3025-3029
-
-
Krones-Herzig, A.1
Mesaros, A.2
Metzger, D.3
Ziegler, A.4
Lemke, U.5
Bruning, J.C.6
Herzig, S.7
-
18
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
Puigserver, P., Rhee, J., Donovan, J., Walkey, C. J., Yoon, J. C., Oriente, F., Kitamura, Y., Altomonte, J., Dong, H., Accili, D. and Spiegelman, B. M. (2003) Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature 423, 550-555.
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
19
-
-
0035855858
-
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
-
Yoon, J. C., Puigserver, P., Chen, G., Donovan, J., Wu, Z., Rhee, J., Adelmant, G., Stafford, J., Kahn, C. R., Granner, D. K., Newgard, C. B. and Spiegelman, B. M. (2001) Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. Nature 413, 131-138.
-
(2001)
Nature
, vol.413
, pp. 131-138
-
-
Yoon, J.C.1
Puigserver, P.2
Chen, G.3
Donovan, J.4
Wu, Z.5
Rhee, J.6
Adelmant, G.7
Stafford, J.8
Kahn, C.R.9
Granner, D.K.10
Newgard, C.B.11
Spiegelman, B.M.12
-
20
-
-
77957768686
-
AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner
-
Lee, J. M., Seo, W. Y., Song, K. H., Chanda, D., Kim, Y. D., Kim, D. K., Lee, M. W., Ryu, D., Kim, Y. H., Noh, J. R., Lee, C. H., Chiang, J. Y., Koo, S. H. and Choi, H. S. (2010) AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner. J. Biol. Chem. 285, 32182-32191.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 32182-32191
-
-
Lee, J.M.1
Seo, W.Y.2
Song, K.H.3
Chanda, D.4
Kim, Y.D.5
Kim, D.K.6
Lee, M.W.7
Ryu, D.8
Kim, Y.H.9
Noh, J.R.10
Lee, C.H.11
Chiang, J.Y.12
Koo, S.H.13
Choi, H.S.14
-
21
-
-
70350463602
-
DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression
-
Nedumaran, B., Hong, S., Xie, Y. B., Kim, Y. H., Seo, W. Y., Lee, M. W., Lee, C. H., Koo, S. H. and Choi, H. S. (2009) DAX-1 acts as a novel corepressor of orphan nuclear receptor HNF4alpha and negatively regulates gluconeogenic enzyme gene expression. J. Biol. Chem. 284, 27511-27523.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27511-27523
-
-
Nedumaran, B.1
Hong, S.2
Xie, Y.B.3
Kim, Y.H.4
Seo, W.Y.5
Lee, M.W.6
Lee, C.H.7
Koo, S.H.8
Choi, H.S.9
-
22
-
-
84866890442
-
TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver
-
Oh, K. J., Park, J., Kim, S. S., Oh, H., Choi, C. S. and Koo, S. H. (2012) TCF7L2 modulates glucose homeostasis by regulating CREB- and FoxO1-dependent transcriptional pathway in the liver. PloS. Genetics. 8, e1002986.
-
(2012)
PloS. Genetics.
, vol.8
-
-
Oh, K.J.1
Park, J.2
Kim, S.S.3
Oh, H.4
Choi, C.S.5
Koo, S.H.6
-
23
-
-
0024445798
-
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
-
Gonzalez, G. A. and Montminy, M. R. (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell. 59, 675-680.
-
(1989)
Cell.
, vol.59
, pp. 675-680
-
-
Gonzalez, G.A.1
Montminy, M.R.2
-
24
-
-
0028060030
-
Activation of cAMP and mitogen responsive genes relies on a common nuclear factor
-
Arias, J., Alberts, A. S., Brindle, P., Claret, F. X., Smeal, T., Karin, M., Feramisco, J. and Montminy, M. (1994) Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370, 226-229.
-
(1994)
Nature
, vol.370
, pp. 226-229
-
-
Arias, J.1
Alberts, A.S.2
Brindle, P.3
Claret, F.X.4
Smeal, T.5
Karin, M.6
Feramisco, J.7
Montminy, M.8
-
25
-
-
0027433708
-
Phosphorylated CREB binds specifically to the nuclear protein CBP
-
Chrivia, J. C., Kwok, R. P., Lamb, N., Hagiwara, M., Montminy, M. R. and Goodman, R. H. (1993) Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365, 855-859.
-
(1993)
Nature
, vol.365
, pp. 855-859
-
-
Chrivia, J.C.1
Kwok, R.P.2
Lamb, N.3
Hagiwara, M.4
Montminy, M.R.5
Goodman, R.H.6
-
26
-
-
0028060029
-
Nuclear protein CBP is a coactivator for the transcription factor CREB
-
Kwok, R. P., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bachinger, H. P., Brennan, R. G., Roberts, S. G., Green, M. R. and Goodman, R. H. (1994) Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370, 223-226.
-
(1994)
Nature
, vol.370
, pp. 223-226
-
-
Kwok, R.P.1
Lundblad, J.R.2
Chrivia, J.C.3
Richards, J.P.4
Bachinger, H.P.5
Brennan, R.G.6
Roberts, S.G.7
Green, M.R.8
Goodman, R.H.9
-
27
-
-
0038185273
-
Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness
-
Conkright, M. D., Guzman, E., Flechner, L., Su, A. I., Hogenesch, J. B. and Montminy, M. (2003) Genome-wide analysis of CREB target genes reveals a core promoter requirement for cAMP responsiveness. Mol. Cell. 11, 1101-1108.
-
(2003)
Mol. Cell.
, vol.11
, pp. 1101-1108
-
-
Conkright, M.D.1
Guzman, E.2
Flechner, L.3
Su, A.I.4
Hogenesch, J.B.5
Montminy, M.6
-
28
-
-
0142091390
-
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells
-
Iourgenko, V., Zhang, W., Mickanin, C., Daly, I., Jiang, C., Hexham, J. M., Orth, A. P., Miraglia, L., Meltzer, J., Garza, D., Chirn, G. W., McWhinnie, E., Cohen, D., Skelton, J., Terry, R., Yu, Y., Bodian, D., Buxton, F. P., Zhu, J., Song, C. and Labow, M. A. (2003) Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells. Proc. Natl. Acad. Sci. U. S. A. 100, 12147-12152.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 12147-12152
-
-
Iourgenko, V.1
Zhang, W.2
Mickanin, C.3
Daly, I.4
Jiang, C.5
Hexham, J.M.6
Orth, A.P.7
Miraglia, L.8
Meltzer, J.9
Garza, D.10
Chirn, G.W.11
McWhinnie, E.12
Cohen, D.13
Skelton, J.14
Terry, R.15
Yu, Y.16
Bodian, D.17
Buxton, F.P.18
Zhu, J.19
Song, C.20
Labow, M.A.21
more..
-
29
-
-
0028229873
-
Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on Ser-133 is transcriptionally active upon its introduction into fibroblast nuclei
-
Alberts, A. S., Arias, J., Hagiwara, M., Montminy, M. R. and Feramisco, J. R. (1994) Recombinant cyclic AMP response element binding protein (CREB) phosphorylated on Ser-133 is transcriptionally active upon its introduction into fibroblast nuclei. J. Biol. Chem. 269, 7623-7630.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 7623-7630
-
-
Alberts, A.S.1
Arias, J.2
Hagiwara, M.3
Montminy, M.R.4
Feramisco, J.R.5
-
30
-
-
0027221605
-
Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation
-
Wadzinski, B. E., Wheat, W. H., Jaspers, S., Peruski, L. F. Jr., Lickteig, R. L., Johnson, G. L. and Klemm, D. J. (1993) Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation. Mol. Cell. Biol. 13, 2822-2834.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2822-2834
-
-
Wadzinski, B.E.1
Wheat, W.H.2
Jaspers, S.3
Peruski, L.F.4
Lickteig, R.L.5
Johnson, G.L.6
Klemm, D.J.7
-
31
-
-
0030998776
-
Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression
-
Hanson, R. W. and Reshef, L. (1997) Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. Annu. Rev. Biochem. 66, 581-611.
-
(1997)
Annu. Rev. Biochem.
, vol.66
, pp. 581-611
-
-
Hanson, R.W.1
Reshef, L.2
-
32
-
-
70449927254
-
Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein
-
Erion, D. M., Ignatova, I. D., Yonemitsu, S., Nagai, Y., Chatterjee, P., Weismann, D. Hsiao, J. J., Zhang, D., Iwasaki, T., Stark, R., Flannery, C., Kahn, M., Carmean, C. M., Yu, X. X., Murray, S. F., Bhanot, S., Monia, B. P., Cline, G. W., Samuel, V. T. and Shulman, G. I. (2009) Prevention of hepatic steatosis and hepatic insulin resistance by knockdown of cAMP response element-binding protein. Cell Metab. 10, 499-506.
-
(2009)
Cell Metab.
, vol.10
, pp. 499-506
-
-
Erion, D.M.1
Ignatova, I.D.2
Yonemitsu, S.3
Nagai, Y.4
Chatterjee, P.5
Weismann, D.6
Hsiao, J.J.7
Zhang, D.8
Iwasaki, T.9
Stark, R.10
Flannery, C.11
Kahn, M.12
Carmean, C.M.13
Yu, X.X.14
Murray, S.F.15
Bhanot, S.16
Monia, B.P.17
Cline, G.W.18
Samuel, V.T.19
Shulman, G.I.20
more..
-
33
-
-
0030480969
-
The CBP co-activator is a histone acetyltransferase
-
Bannister, A. J. and Kouzarides, T. (1996) The CBP co-activator is a histone acetyltransferase. Nature 384, 641-643.
-
(1996)
Nature
, vol.384
, pp. 641-643
-
-
Bannister, A.J.1
Kouzarides, T.2
-
34
-
-
0030606239
-
The transcriptional coactivators p300 and CBP are histone acetyltransferases
-
Ogryzko, V. V., Schiltz, R. L., Russanova, V., Howard, B. H. and Nakatani, Y. (1996) The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell. 87, 953-959.
-
(1996)
Cell.
, vol.87
, pp. 953-959
-
-
Ogryzko, V.V.1
Schiltz, R.L.2
Russanova, V.3
Howard, B.H.4
Nakatani, Y.5
-
35
-
-
0030923585
-
Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome
-
Tanaka, Y., Naruse, I., Maekawa, T., Masuya, H., Shiroishi, T. and Ishii, S. (1997) Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome. Proc. Natl. Acad. Sci. U. S. A. 94, 10215-10220.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 10215-10220
-
-
Tanaka, Y.1
Naruse, I.2
Maekawa, T.3
Masuya, H.4
Shiroishi, T.5
Ishii, S.6
-
36
-
-
17644445419
-
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
-
Yao, T. P., Oh, S. P., Fuchs, M., Zhou, N. D., Ch'ng, L. E., Newsome, D., Bronson, R. T., Li, E., Livingston, D. M. and Eckner, R. (1998) Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 93, 361-372.
-
(1998)
Cell.
, vol.93
, pp. 361-372
-
-
Yao, T.P.1
Oh, S.P.2
Fuchs, M.3
Zhou, N.D.4
Ch'ng, L.E.5
Newsome, D.6
Bronson, R.T.7
Li, E.8
Livingston, D.M.9
Eckner, R.10
-
37
-
-
0036478904
-
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice
-
Yamauchi, T., Oike, Y., Kamon, J., Waki, H., Komeda, K., Tsuchida, A., Date, Y., Li, M. X., Miki, H., Akanuma, Y., Nagai, R., Kimura, S., Saheki, T., Nakazato, M., Naitoh, T., Yamamura, K. and Kadowaki, T. (2002) Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice. Nat. Genet. 30, 221-226.
-
(2002)
Nat. Genet.
, vol.30
, pp. 221-226
-
-
Yamauchi, T.1
Oike, Y.2
Kamon, J.3
Waki, H.4
Komeda, K.5
Tsuchida, A.6
Date, Y.7
Li, M.X.8
Miki, H.9
Akanuma, Y.10
Nagai, R.11
Kimura, S.12
Saheki, T.13
Nakazato, M.14
Naitoh, T.15
Yamamura, K.16
Kadowaki, T.17
-
38
-
-
65549136655
-
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein
-
He, L., Sabet, A., Djedjos, S., Miller, R., Sun, X., Hussain, M. A., Radovick, S. and Wondisford, F. E. (2009) Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein. Cell. 137, 635-646.
-
(2009)
Cell.
, vol.137
, pp. 635-646
-
-
He, L.1
Sabet, A.2
Djedjos, S.3
Miller, R.4
Sun, X.5
Hussain, M.A.6
Radovick, S.7
Wondisford, F.E.8
-
39
-
-
14544289119
-
Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver
-
Dentin, R., Girard, J. and Postic, C. (2005) Carbohydrate responsive element binding protein (ChREBP) and sterol regulatory element binding protein-1c (SREBP-1c): two key regulators of glucose metabolism and lipid synthesis in liver. Biochimie. 87, 81-86.
-
(2005)
Biochimie.
, vol.87
, pp. 81-86
-
-
Dentin, R.1
Girard, J.2
Postic, C.3
-
40
-
-
79951962147
-
CREB and the CRTC co-activators: sensors for hormonal and metabolic signals
-
Altarejos, J. Y. and Montminy, M. (2011) CREB and the CRTC co-activators: sensors for hormonal and metabolic signals. Nat. Rev. Mol. Cell Biol. 12, 141-151.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 141-151
-
-
Altarejos, J.Y.1
Montminy, M.2
-
41
-
-
78049292405
-
Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis
-
Yoon, Y. S., Lee, M. W., Ryu, D., Kim, J. H., Ma, H., Seo, W. Y., Kim, Y. N., Kim, S. S., Lee, C. H., Hunter, T., Choi, C. S., Montminy, M. R. and Koo, S. H. (2010) Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis. Proc. Natl. Acad. Sci. U.S.A. 107, 17704-17709.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 17704-17709
-
-
Yoon, Y.S.1
Lee, M.W.2
Ryu, D.3
Kim, J.H.4
Ma, H.5
Seo, W.Y.6
Kim, Y.N.7
Kim, S.S.8
Lee, C.H.9
Hunter, T.10
Choi, C.S.11
Montminy, M.R.12
Koo, S.H.13
-
42
-
-
84860510820
-
Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes
-
Wang, Y., Li, G., Goode, J., Paz, J. C., Ouyang, K., Screaton, R., Fischer, W. H., Chen, J., Tabas, I. and Montminy, M. (2012) Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature 485, 128-132.
-
(2012)
Nature
, vol.485
, pp. 128-132
-
-
Wang, Y.1
Li, G.2
Goode, J.3
Paz, J.C.4
Ouyang, K.5
Screaton, R.6
Fischer, W.H.7
Chen, J.8
Tabas, I.9
Montminy, M.10
-
43
-
-
70249127893
-
Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis
-
Yoon, Y. S., Ryu, D., Lee, M. W., Hong, S. and Koo, S. H. (2009) Adiponectin and thiazolidinedione targets CRTC2 to regulate hepatic gluconeogenesis. Exp. Mol. Med. 41, 577-583.
-
(2009)
Exp. Mol. Med.
, vol.41
, pp. 577-583
-
-
Yoon, Y.S.1
Ryu, D.2
Lee, M.W.3
Hong, S.4
Koo, S.H.5
-
44
-
-
70350447639
-
Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes
-
Saberi, M., Bjelica, D., Schenk, S., Imamura, T., Bandyopadhyay, G., Li, P., Vargeese, C., Wang, W., Bowman, K., Zhang, Y., Polisky, B. and Olefsky, J. M. (2009) Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes. Am. J. Physiol. Endocrinol. Metab. 297, E1137-1146.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
-
-
Saberi, M.1
Bjelica, D.2
Schenk, S.3
Imamura, T.4
Bandyopadhyay, G.5
Li, P.6
Vargeese, C.7
Wang, W.8
Bowman, K.9
Zhang, Y.10
Polisky, B.11
Olefsky, J.M.12
-
45
-
-
77649253906
-
Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity
-
Wang, Y., Inoue, H., Ravnskjaer, K., Viste, K., Miller, N., Liu, Y., Hedrick, S., Vera, L. and Montminy, M. (2010) Targeted disruption of the CREB coactivator Crtc2 increases insulin sensitivity. Proc. Natl. Acad. Sci. U. S. A. 107, 3087-3092.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 3087-3092
-
-
Wang, Y.1
Inoue, H.2
Ravnskjaer, K.3
Viste, K.4
Miller, N.5
Liu, Y.6
Hedrick, S.7
Vera, L.8
Montminy, M.9
-
46
-
-
67749135249
-
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
-
Wang, Y., Vera, L., Fischer, W. H. and Montminy, M. (2009) The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis. Nature 460, 534-537.
-
(2009)
Nature
, vol.460
, pp. 534-537
-
-
Wang, Y.1
Vera, L.2
Fischer, W.H.3
Montminy, M.4
-
47
-
-
60649114293
-
TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1
-
Ryu, D., Oh, K. J., Jo, H. Y., Hedrick, S., Kim, Y. N., Hwang, Y. J., Park, T. S., Han, J. S., Choi, C. S., Montminy M. and Koo, S. H. (2009) TORC2 regulates hepatic insulin signaling via a mammalian phosphatidic acid phosphatase, LIPIN1. Cell Metab. 9, 240-251.
-
(2009)
Cell Metab.
, vol.9
, pp. 240-251
-
-
Ryu, D.1
Oh, K.J.2
Jo, H.Y.3
Hedrick, S.4
Kim, Y.N.5
Hwang, Y.J.6
Park, T.S.7
Han, J.S.8
Choi, C.S.9
Montminy, M.10
Koo, S.H.11
-
48
-
-
2342496712
-
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
-
Accili, D. and Arden, K. C. (2004) FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117, 421-426.
-
(2004)
Cell
, vol.117
, pp. 421-426
-
-
Accili, D.1
Arden, K.C.2
-
49
-
-
18044381312
-
FoxO proteins in insulin action and metabolism
-
Barthel, A., Schmoll, D. and Unterman, T. G. (2005) FoxO proteins in insulin action and metabolism. Trends Endocrinol. Metab. 16, 183-189.
-
(2005)
Trends Endocrinol. Metab.
, vol.16
, pp. 183-189
-
-
Barthel, A.1
Schmoll, D.2
Unterman, T.G.3
-
50
-
-
0033595011
-
Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
-
Biggs, W. H., 3rd, Meisenhelder, J., Hunter, T., Cavenee, W. K. and Arden, K. C. (1999) Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl. Acad. Sci. U. S. A. 96, 7421-7426.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 7421-7426
-
-
Biggs, W.H.1
Meisenhelder, J.2
Hunter, T.3
Cavenee, W.K.4
Arden, K.C.5
-
51
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J. and Greenberg, M. E. (1999) Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 96, 857-868.
-
(1999)
Cell.
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
52
-
-
0033522897
-
Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway
-
Nakae, J., Park, B. C. and Accili, D. (1999) Insulin stimulates phosphorylation of the forkhead transcription factor FKHR on serine 253 through a Wortmannin-sensitive pathway. J. Biol. Chem. 274, 15982-15985.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15982-15985
-
-
Nakae, J.1
Park, B.C.2
Accili, D.3
-
53
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
Daitoku, H., Hatta, M., Matsuzaki, H., Aratani, S., Ohshima, T., Miyagishi, M., Nakajima, T. and Fukamizu, A. (2004) Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc. Natl. Acad. Sci. U. S. A. 101, 10042-10047.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
54
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta, M. C., Divecha, N., Lemieux, M., Kamel, C., Chen, D., Gu, W., Bultsma, Y., McBurney, M. and Guarente, L. (2004) Mammalian SIRT1 represses forkhead transcription factors. Cell. 116, 551-563.
-
(2004)
Cell.
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
55
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
-
van der Horst, A., Tertoolen, L. G., de Vries-Smits, L. M., Frye, R. A., Medema, R. H. and Burgering, B. M. (2004) FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J. Biol. Chem. 279, 28873-28879.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28873-28879
-
-
van der Horst, A.1
Tertoolen, L.G.2
de Vries-Smits, L.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.6
-
56
-
-
78149272381
-
FoxOs function synergistically to promote glucose production
-
Haeusler, R. A., Kaestner, K. H. and Accili, D. (2010) FoxOs function synergistically to promote glucose production. J. Biol. Chem. 285, 35245-35248.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35245-35248
-
-
Haeusler, R.A.1
Kaestner, K.H.2
Accili, D.3
-
57
-
-
0032830572
-
Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence
-
Ayala, J. E., Streeper, R. S., Desgrosellier, J. S., Durham, S. K., Suwanichkul, A., Svitek, C. A., Goldman, J. K., Barr, F. G., Powell, D. R. and O'Brien, R. M. (1999) Conservation of an insulin response unit between mouse and human glucose-6-phosphatase catalytic subunit gene promoters: transcription factor FKHR binds the insulin response sequence. Diabetes. 48, 1885-1889.
-
(1999)
Diabetes.
, vol.48
, pp. 1885-1889
-
-
Ayala, J.E.1
Streeper, R.S.2
Desgrosellier, J.S.3
Durham, S.K.4
Suwanichkul, A.5
Svitek, C.A.6
Goldman, J.K.7
Barr, F.G.8
Powell, D.R.9
O'Brien, R.M.10
-
58
-
-
34548349302
-
Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver
-
Matsumoto, M., Pocai, A., Rossetti, L., Depinho, R. A. and Accili, D. (2007) Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver. Cell Metab. 6, 208-216.
-
(2007)
Cell Metab.
, vol.6
, pp. 208-216
-
-
Matsumoto, M.1
Pocai, A.2
Rossetti, L.3
Depinho, R.A.4
Accili, D.5
-
59
-
-
80755148700
-
FoxO6 integrates insulin signaling with gluconeogenesis in the liver
-
Kim, D. H., Perdomo, G., Zhang, T., Slusher, S., Lee, S., Phillips, B. E., Fan, Y., Giannoukakis, N., Gramignoli, R., Strom, S., Ringquist, S. and Dong, H. H. (2011) FoxO6 integrates insulin signaling with gluconeogenesis in the liver. Diabetes. 60, 2763-2774.
-
(2011)
Diabetes.
, vol.60
, pp. 2763-2774
-
-
Kim, D.H.1
Perdomo, G.2
Zhang, T.3
Slusher, S.4
Lee, S.5
Phillips, B.E.6
Fan, Y.7
Giannoukakis, N.8
Gramignoli, R.9
Strom, S.10
Ringquist, S.11
Dong, H.H.12
-
60
-
-
0032549811
-
A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
-
Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M. and Spiegelman, B. M. (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell. 92, 829-839.
-
(1998)
Cell.
, vol.92
, pp. 829-839
-
-
Puigserver, P.1
Wu, Z.2
Park, C.W.3
Graves, R.4
Wright, M.5
Spiegelman, B.M.6
-
61
-
-
0032589689
-
Activation of PPARgamma coactivator-1 through transcription factor docking
-
Puigserver, P., Adelmant, G., Wu, Z., Fan, M., Xu, J., O'Malley, B. and Spiegelman, B. M. (1999) Activation of PPARgamma coactivator-1 through transcription factor docking. Science 286, 1368-1371.
-
(1999)
Science
, vol.286
, pp. 1368-1371
-
-
Puigserver, P.1
Adelmant, G.2
Wu, Z.3
Fan, M.4
Xu, J.5
O'Malley, B.6
Spiegelman, B.M.7
-
62
-
-
0344413490
-
Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha
-
Wallberg, A. E., Yamamura, S., Malik, S., Spiegelman, B. M. and Roeder, R. G. (2003) Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha. Mol. Cell. 12, 1137-1149.
-
(2003)
Mol. Cell.
, vol.12
, pp. 1137-1149
-
-
Wallberg, A.E.1
Yamamura, S.2
Malik, S.3
Spiegelman, B.M.4
Roeder, R.G.5
-
63
-
-
24144463983
-
Metabolic control through the PGC-1 family of transcription coactivators
-
Lin, J., Handschin, C. and Spiegelman, B. M. (2005) Metabolic control through the PGC-1 family of transcription coactivators. Cell. Metab. 1, 361-370.
-
(2005)
Cell. Metab.
, vol.1
, pp. 361-370
-
-
Lin, J.1
Handschin, C.2
Spiegelman, B.M.3
-
64
-
-
84864391371
-
Identification of interacting proteins of retinoid-related orphan nuclear receptor gamma in HepG2 cells
-
Huang, Z. M., Wu, J., Jia, Z. C., Tian, Y., Tang, J., Tang, Y., Wang, Y., Wu, Y. Z. and Ni, B. (2012) Identification of interacting proteins of retinoid-related orphan nuclear receptor gamma in HepG2 cells. BMB Rep. 45, 331-336.
-
(2012)
BMB Rep.
, vol.45
, pp. 331-336
-
-
Huang, Z.M.1
Wu, J.2
Jia, Z.C.3
Tian, Y.4
Tang, J.5
Tang, Y.6
Wang, Y.7
Wu, Y.Z.8
Ni, B.9
-
65
-
-
2442701392
-
PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3
-
Koo, S. H., Satoh, H., Herzig, S., Lee, C. H., Hedrick, S., Kulkarni, R., Evans, R. M., Olefsky, J. and Montminy, M. (2004) PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat. Med. 10, 530-534.
-
(2004)
Nat. Med.
, vol.10
, pp. 530-534
-
-
Koo, S.H.1
Satoh, H.2
Herzig, S.3
Lee, C.H.4
Hedrick, S.5
Kulkarni, R.6
Evans, R.M.7
Olefsky, J.8
Montminy, M.9
-
66
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin, J., Wu, P. H., Tarr, P. T., Lindenberg, K. S., St-Pierre, J., Zhang, C. Y., Mootha, V. K., Jager, S., Vianna, C. R., Reznick, R. M., Cui, L., Manieri, M., Donovan, M. X., Wu, Z., Cooper, M. P., Fan, M. C., Rohas, L. M., Zavacki, A. M., Cinti, S., Shulman, G. I., Lowell, B. B., Krainc, D. and Spiegelman, B. M. (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119, 121-135.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
67
-
-
84876725213
-
Protein arginine methylation in hepatic glucose metabolism regulation: Histone or nonhistone? That is the question
-
Choi, D., Oh, K. J. and Koo, S. H. (2013) Protein arginine methylation in hepatic glucose metabolism regulation: Histone or nonhistone? That is the question. Reply. Hepatology. 57, 2091.
-
(2013)
Reply. Hepatology.
, vol.57
, pp. 2091
-
-
Choi, D.1
Oh, K.J.2
Koo, S.H.3
-
68
-
-
79955608146
-
Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16
-
Takahashi, Y., Daitoku, H., Hirota, K., Tamiya, H., Yokoyama, A., Kako, K., Nagashima, Y., Nakamura, A., Shimada, T., Watanabe, S., Yamagata, K., Yasuda, K., Ishii, N. and Fukamizu, A. (2011) Asymmetric arginine dimethylation determines life span in C. elegans by regulating forkhead transcription factor DAF-16. Cell Metab. 13, 505-516.
-
(2011)
Cell Metab.
, vol.13
, pp. 505-516
-
-
Takahashi, Y.1
Daitoku, H.2
Hirota, K.3
Tamiya, H.4
Yokoyama, A.5
Kako, K.6
Nagashima, Y.7
Nakamura, A.8
Shimada, T.9
Watanabe, S.10
Yamagata, K.11
Yasuda, K.12
Ishii, N.13
Fukamizu, A.14
-
69
-
-
53949087832
-
Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt
-
Yamagata, K., Daitoku, H., Takahashi, Y., Namiki, K., Hisatake, K., Kako, K., Mukai, H., Kasuya, Y. and Fukamizu, A. (2008) Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol. Cell. 32, 221-231.
-
(2008)
Mol. Cell.
, vol.32
, pp. 221-231
-
-
Yamagata, K.1
Daitoku, H.2
Takahashi, Y.3
Namiki, K.4
Hisatake, K.5
Kako, K.6
Mukai, H.7
Kasuya, Y.8
Fukamizu, A.9
-
70
-
-
4944263717
-
Molecular mechanisms of DAX1 action
-
Iyer, A. K. and McCabe, E. R. (2004) Molecular mechanisms of DAX1 action. Mol. Genet. Metab. 83, 60-73.
-
(2004)
Mol. Genet. Metab.
, vol.83
, pp. 60-73
-
-
Iyer, A.K.1
McCabe, E.R.2
-
71
-
-
0030001371
-
An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors
-
Seol, W., Choi, H. S. and Moore, D. D. (1996) An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors. Science 272, 1336-1339.
-
(1996)
Science
, vol.272
, pp. 1336-1339
-
-
Seol, W.1
Choi, H.S.2
Moore, D.D.3
-
72
-
-
43449097571
-
Molecular basis of endocrine regulation by orphan nuclear receptor Small Heterodimer Partner
-
Chanda, D., Park, J. H. and Choi, H. S. (2008) Molecular basis of endocrine regulation by orphan nuclear receptor Small Heterodimer Partner. Endocr. J. 55, 253-268.
-
(2008)
Endocr. J.
, vol.55
, pp. 253-268
-
-
Chanda, D.1
Park, J.H.2
Choi, H.S.3
-
73
-
-
34249793707
-
Structure and function of the atypical orphan nuclear receptor small heterodimer partner
-
Lee, Y. S., Chanda, D., Sim, J., Park, Y. Y. and Choi, H. S. (2007) Structure and function of the atypical orphan nuclear receptor small heterodimer partner. Int. Rev. Cytol. 261, 117-158.
-
(2007)
Int. Rev. Cytol.
, vol.261
, pp. 117-158
-
-
Lee, Y.S.1
Chanda, D.2
Sim, J.3
Park, Y.Y.4
Choi, H.S.5
-
74
-
-
40749116561
-
Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase- dependent regulation of the orphan nuclear receptor SHP
-
Kim, Y. D., Park, K. G., Lee, Y. S., Park, Y. Y., Kim, D. K., Nedumaran, B., Jang, W. G., Cho, W. J., Ha, J., Lee, I. K., Lee, C. H. and Choi, H. S. (2008) Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase- dependent regulation of the orphan nuclear receptor SHP. Diabetes 57, 306-314.
-
(2008)
Diabetes
, vol.57
, pp. 306-314
-
-
Kim, Y.D.1
Park, K.G.2
Lee, Y.S.3
Park, Y.Y.4
Kim, D.K.5
Nedumaran, B.6
Jang, W.G.7
Cho, W.J.8
Ha, J.9
Lee, I.K.10
Lee, C.H.11
Choi, H.S.12
-
75
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens, J., von Kries, J. P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R. and Birchmeier W. (1996) Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382, 638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
von Kries, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
76
-
-
0345343608
-
Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
-
Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B. G. and Kemler, R. (1996) Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech. Dev. 59, 3-10.
-
(1996)
Mech. Dev.
, vol.59
, pp. 3-10
-
-
Huber, O.1
Korn, R.2
McLaughlin, J.3
Ohsugi, M.4
Herrmann, B.G.5
Kemler, R.6
-
77
-
-
0001003110
-
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
-
Molenaar, M., van de Wetering, M., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destree, O. and Clevers, H. (1996) XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 86, 391-399.
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
van de Wetering, M.2
Oosterwegel, M.3
Peterson-Maduro, J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
78
-
-
0030900696
-
Stabilization of beta-catenin by genetic defects in melanoma cell lines
-
Rubinfeld, B., Robbins, P., El-Gamil, M., Albert, I., Porfiri, E. and Polakis, P. (1997) Stabilization of beta-catenin by genetic defects in melanoma cell lines. Science 275, 1790-1792.
-
(1997)
Science
, vol.275
, pp. 1790-1792
-
-
Rubinfeld, B.1
Robbins, P.2
El-Gamil, M.3
Albert, I.4
Porfiri, E.5
Polakis, P.6
-
79
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers, H. (2006) Wnt/beta-catenin signaling in development and disease. Cell 127, 469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
80
-
-
33845936147
-
Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population
-
Chandak, G. R., Janipalli, C. S., Bhaskar, S., Kulkarni, S. R., Mohankrishna, P., Hattersley, A. T., Frayling, T. M. and Yajnik, C. S. (2007) Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population. Diabetologia 50, 63-67.
-
(2007)
Diabetologia
, vol.50
, pp. 63-67
-
-
Chandak, G.R.1
Janipalli, C.S.2
Bhaskar, S.3
Kulkarni, S.R.4
Mohankrishna, P.5
Hattersley, A.T.6
Frayling, T.M.7
Yajnik, C.S.8
-
81
-
-
32544451924
-
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
-
Grant, S. F., Thorleifsson, G., Reynisdottir, I., Benediktsson, R., Manolescu, A., Sainz, J., Helgason, A., Stefansson, H., Emilsson, V., Helgadottir, A., Styrkarsdottir, U., Magnusson, K. P., Walters, G. B., Palsdottir, E., Jonsdottir, T., Gudmundsdottir, T., Gylfason, A., Saemundsdottir, J., Wilensky, R. L., Reilly, M. P., Rader, D. J., Bagger, Y., Christiansen, C., Gudnason, V., Sigurdsson, G., Thorsteinsdottir, U., Gulcher, J. R., Kong, A. and Stefansson, K. (2006) Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat. Genet. 38, 320-323.
-
(2006)
Nat. Genet.
, vol.38
, pp. 320-323
-
-
Grant, S.F.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Manolescu, A.5
Sainz, J.6
Helgason, A.7
Stefansson, H.8
Emilsson, V.9
Helgadottir, A.10
Styrkarsdottir, U.11
Magnusson, K.P.12
Walters, G.B.13
Palsdottir, E.14
Jonsdottir, T.15
Gudmundsdottir, T.16
Gylfason, A.17
Saemundsdottir, J.18
Wilensky, R.L.19
Reilly, M.P.20
Rader, D.J.21
Bagger, Y.22
Christiansen, C.23
Gudnason, V.24
Sigurdsson, G.25
Thorsteinsdottir, U.26
Gulcher, J.R.27
Kong, A.28
Stefansson, K.29
more..
-
82
-
-
34147119644
-
Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population
-
Hayashi, T., Iwamoto, Y., Kaku, K., Hirose, H. and Maeda, S. (2007) Replication study for the association of TCF7L2 with susceptibility to type 2 diabetes in a Japanese population. Diabetologia 50, 980-984.
-
(2007)
Diabetologia
, vol.50
, pp. 980-984
-
-
Hayashi, T.1
Iwamoto, Y.2
Kaku, K.3
Hirose, H.4
Maeda, S.5
-
83
-
-
33846596193
-
Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution
-
Helgason, A., Palsson, S., Thorleifsson, G., Grant, S. F., Emilsson, V., Gunnarsdottir, S., Adeyemo, A., Chen, Y., Chen, G., Reynisdottir, I., Benediktsson, R., Hinney, A., Hansen, T., Andersen, G., Borch-Johnsen, K., Jorgensen, T., Schafer, H., Faruque, M., Doumatey, A., Zhou, J., Wilensky, R. L., Reilly, M. P., Rader, D. J., Bagger, Y., Christiansen, C., Sigurdsson, G., Hebebrand, J., Pedersen, O., Thorsteinsdottir, U., Gulcher, J. R., Kong, A., Rotimi, C. and Stefansson, K. (2007) Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat. Genet. 39, 218-225.
-
(2007)
Nat. Genet.
, vol.39
, pp. 218-225
-
-
Helgason, A.1
Palsson, S.2
Thorleifsson, G.3
Grant, S.F.4
Emilsson, V.5
Gunnarsdottir, S.6
Adeyemo, A.7
Chen, Y.8
Chen, G.9
Reynisdottir, I.10
Benediktsson, R.11
Hinney, A.12
Hansen, T.13
Andersen, G.14
Borch-Johnsen, K.15
Jorgensen, T.16
Schafer, H.17
Faruque, M.18
Doumatey, A.19
Zhou, J.20
Wilensky, R.L.21
Reilly, M.P.22
Rader, D.J.23
Bagger, Y.24
Christiansen, C.25
Sigurdsson, G.26
Hebebrand, J.27
Pedersen, O.28
Thorsteinsdottir, U.29
Gulcher, J.R.30
Kong, A.31
Rotimi, C.32
Stefansson, K.33
more..
-
84
-
-
33847014094
-
Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans
-
Lehman, D. M., Hunt, K. J., Leach, R. J., Hamlington, J., Arya, R., Abboud, H. E., Duggirala, R., Blangero, J., Goring, H. H. and Stern, M. P. (2007) Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of onset in Mexican Americans. Diabetes 56, 389-393.
-
(2007)
Diabetes
, vol.56
, pp. 389-393
-
-
Lehman, D.M.1
Hunt, K.J.2
Leach, R.J.3
Hamlington, J.4
Arya, R.5
Abboud, H.E.6
Duggirala, R.7
Blangero, J.8
Goring, H.H.9
Stern, M.P.10
-
85
-
-
12544254474
-
TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase- 3beta
-
Yi, F., Brubaker, P. L. and Jin, T. (2005) TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase- 3beta. J. Biol. Chem. 280, 1457-1464.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 1457-1464
-
-
Yi, F.1
Brubaker, P.L.2
Jin, T.3
-
86
-
-
82455212297
-
Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism
-
Norton, L., Fourcaudot, M., Abdul-Ghani, M. A., Winnier, D., Mehta, F. F., Jenkinson, C. P. and Defronzo, R. A. (2011) Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism. Diabetologia 54, 3132-3142.
-
(2011)
Diabetologia
, vol.54
, pp. 3132-3142
-
-
Norton, L.1
Fourcaudot, M.2
Abdul-Ghani, M.A.3
Winnier, D.4
Mehta, F.F.5
Jenkinson, C.P.6
Defronzo, R.A.7
|