Orphan nuclear receptor estrogen-related receptor γ(ERRγ) is key regulator of hepatic gluconeogenesis

Journal of Biological Chemistry

Volumn 287, Issue 26, 2012, Pages 21628-21639

  Kim, Don Kyu ^a   Ryu, Dongryeol ^b   Koh, Minseob ^c   Lee, Min Woo ^b   Lim, Donghyun ^c   Kim, Min Jung ^b   Kim, Yong Hoon ^d   Cho, Won Jea ^a   Lee, Chul Ho ^d   Park, Seung Bum ^c   Koo, Seung Hoi ^b   Choi, Hueng Sik ^a,e  

^a Chonnam National University   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c Seoul National University   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^e Chonnam National University Medical School   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DB/DB MOUSE; GENE TRANSCRIPTIONS; GLUCONEOGENIC GENES; GLUCOSE HOMEOSTASIS; GLUCOSE PRODUCTION; HEPATIC GLUCONEOGENESIS; HORMONAL REGULATION; IN-VIVO IMAGING; INSULIN RESISTANCE; KEY REGULATORS; MUTATION ANALYSIS; NUCLEAR RECEPTORS; OVER-EXPRESSION; PRIMARY HEPATOCYTES; RESPONSE ELEMENTS; TRANSCRIPTIONAL ACTIVITY; TYPE-2 DIABETES;

GENES; GLUCOSE; MAMMALS; TRANSCRIPTION;

METABOLISM;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN REGULATED TRANSCRIPTION COACTIVATOR 2; ESTROGEN RECEPTOR; ESTROGEN RELATED RECEPTOR GAMMA; GLUCAGON; GLUCOSE; GSK 5182; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG MECHANISM; ERR GAMMA GENE; ESTROGEN RESPONSIVE ELEMENT; G6PC GENE; GENE; GENE ACTIVATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLYCEMIC CONTROL; HYPERGLYCEMIA; IN VIVO STUDY; INTRACELLULAR SIGNALING; LIVER METABOLISM; MALE; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PCK1 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; TRANSCRIPTION REGULATION;

ANIMALS; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE; HEAT-SHOCK PROTEINS; HEPATOCYTES; HUMANS; INSULIN RESISTANCE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORPHAN NUCLEAR RECEPTORS; PROMOTER REGIONS, GENETIC; RATS; RECEPTORS, ESTROGEN; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS;

EID: 84862653969     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.315168     Document Type: Article

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