TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver

PLoS Genetics

Volumn 8, Issue 9, 2012, Pages

  Oh, Kyoung Jin ^a   Park, Jinyoung ^a   Kim, Su Sung ^b   Oh, Hyunhee ^b   Choi, Cheol Soo ^b   Koo, Seung Hoi ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Gachon University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLUCOSE; INSULIN; TRANSCRIPTION FACTOR 7 LIKE 2; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HAPLOINSUFFICIENCY; HYPERGLYCEMIA; INSULIN RESISTANCE; LIPID DIET; LIVER METABOLISM; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE;

ANIMALS; BLOOD GLUCOSE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; GLUCONEOGENESIS; GLUCOSE; GLUCOSE INTOLERANCE; HUMANS; INSULIN RESISTANCE; LIVER; METABOLIC NETWORKS AND PATHWAYS; MICE; TRANSCRIPTION FACTOR 7-LIKE 2 PROTEIN; TRANSCRIPTION FACTORS;

MAMMALIA; MUS;

EID: 84866890442     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002986     Document Type: Article

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