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Volumn 57, Issue 1-3, 2013, Pages 172-184

Myeloid derived suppressor cells in physiological and pathological conditions: The good, the bad, and the ugly

Author keywords

Carcinogenesis; Chronic inflammation; MDSCs subsets; Myeloid derived suppressor cells; Physiological immune response; Tumor progression

Indexed keywords

ARGINASE 1; CYSTEINE; INDUCIBLE NITRIC OXIDE SYNTHASE;

EID: 84891486024     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-013-8455-2     Document Type: Article
Times cited : (81)

References (150)
  • 1
    • 0021558066 scopus 로고
    • Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: Exploring obscure relationships
    • 6152690 1:STN:280:DyaL28%2FisF2huw%3D%3D
    • Strober S. Natural suppressor (NS) cells, neonatal tolerance, and total lymphoid irradiation: exploring obscure relationships. Annu Rev Immunol. 1984;2:219-37.
    • (1984) Annu Rev Immunol. , vol.2 , pp. 219-237
    • Strober, S.1
  • 2
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells
    • 11090068 1:CAS:528:DC%2BD3cXosVGntbg%3D
    • Bronte V, Apolloni E, Cabrelle A, Ronca R, Serafini P, Zamboni P, et al. Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood. 2000;96(12):3838-46.
    • (2000) Blood , vol.96 , Issue.12 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3    Ronca, R.4    Serafini, P.5    Zamboni, P.6
  • 3
    • 0033757517 scopus 로고    scopus 로고
    • Chemoattraction of femoral CD34+ progenitor cells by tumor-derived vascular endothelial cell growth factor
    • 11089887 1:CAS:528:DC%2BD3cXos1Orsro%3D
    • Young MR, Kolesiak K, Wright MA, Gabrilovich DI. Chemoattraction of femoral CD34+ progenitor cells by tumor-derived vascular endothelial cell growth factor. Clin Exp Metastasis. 1999;17(10):881-8.
    • (1999) Clin Exp Metastasis. , vol.17 , Issue.10 , pp. 881-888
    • Young, M.R.1    Kolesiak, K.2    Wright, M.A.3    Gabrilovich, D.I.4
  • 4
    • 0035164478 scopus 로고    scopus 로고
    • Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
    • 11123353 1:CAS:528:DC%2BD3MXis1elsw%3D%3D
    • Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, et al. Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol. 2001;166(1):678-89.
    • (2001) J Immunol. , vol.166 , Issue.1 , pp. 678-689
    • Almand, B.1    Clark, J.I.2    Nikitina, E.3    Van Beynen, J.4    English, N.R.5    Knight, S.C.6
  • 5
    • 84856899903 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in cancer patients: A clinical perspective
    • 10.1097/CJI.0b013e318242169f 22306898
    • Montero AJ, Diaz-Montero CM, Kyriakopoulos CE, Bronte V, Mandruzzato S. Myeloid-derived suppressor cells in cancer patients: a clinical perspective. J Immunother. 2012;35(2):107-15. doi: 10.1097/CJI.0b013e318242169f.
    • (2012) J Immunother. , vol.35 , Issue.2 , pp. 107-115
    • Montero, A.J.1    Diaz-Montero, C.M.2    Kyriakopoulos, C.E.3    Bronte, V.4    Mandruzzato, S.5
  • 6
    • 84864289043 scopus 로고    scopus 로고
    • Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells
    • 10.1097/QAD.0b013e328354b43f 22526518 1:CAS:528:DC%2BC38XhtVKqu7zE
    • Vollbrecht T, Stirner R, Tufman A, Roider J, Huber RM, Bogner JR, et al. Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells. AIDS. 2012;26(12):F31-7. doi: 10.1097/QAD.0b013e328354b43f.
    • (2012) AIDS. , vol.26 , Issue.12
    • Vollbrecht, T.1    Stirner, R.2    Tufman, A.3    Roider, J.4    Huber, R.M.5    Bogner, J.R.6
  • 7
    • 0025742716 scopus 로고
    • Staphylococcal exotoxins stimulate nitric oxide-dependent murine macrophage tumoricidal activity
    • 1908828 1:CAS:528:DyaK3MXmsFCjtbY%3D
    • Fast DJ, Shannon BJ, Herriott MJ, Kennedy MJ, Rummage JA, Leu RW. Staphylococcal exotoxins stimulate nitric oxide-dependent murine macrophage tumoricidal activity. Infect Immun. 1991;59(9):2987-93.
    • (1991) Infect Immun. , vol.59 , Issue.9 , pp. 2987-2993
    • Fast, D.J.1    Shannon, B.J.2    Herriott, M.J.3    Kennedy, M.J.4    Rummage, J.A.5    Leu, R.W.6
  • 8
    • 0025191261 scopus 로고
    • Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor
    • 2136804 1:CAS:528:DyaK3cXhtlOis7s%3D
    • Fu YX, Watson G, Jimenez JJ, Wang Y, Lopez DM. Expansion of immunoregulatory macrophages by granulocyte-macrophage colony-stimulating factor derived from a murine mammary tumor. Cancer Res. 1990;50:227-34.
    • (1990) Cancer Res. , vol.50 , pp. 227-234
    • Fu, Y.X.1    Watson, G.2    Jimenez, J.J.3    Wang, Y.4    Lopez, D.M.5
  • 9
    • 0141456030 scopus 로고    scopus 로고
    • Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity
    • 12750171 1:CAS:528:DC%2BD3sXntlKrs78%3D
    • Melani C, Chiodoni C, Forni G, Colombo MP. Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity. Blood. 2003;102(6):2138-45.
    • (2003) Blood. , vol.102 , Issue.6 , pp. 2138-2145
    • Melani, C.1    Chiodoni, C.2    Forni, G.3    Colombo, M.P.4
  • 10
    • 0041850021 scopus 로고    scopus 로고
    • Inhibition of myeloid cell differentiation in cancer: The role of reactive oxygen species
    • 12885935 1:CAS:528:DC%2BD3sXmt1Ggtbc%3D
    • Kusmartsev S, Gabrilovich DI. Inhibition of myeloid cell differentiation in cancer: the role of reactive oxygen species. J Leukoc Biol. 2003;74(2):186-96.
    • (2003) J Leukoc Biol. , vol.74 , Issue.2 , pp. 186-196
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 11
    • 0034671610 scopus 로고    scopus 로고
    • Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes
    • 11120790 1:CAS:528:DC%2BD3cXovFyhtLg%3D
    • Apolloni E, Bronte V, Mazzoni A, Serafini P, Cabrelle A, Segal DM, et al. Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes. J Immunol. 2000;165(12):6723-30.
    • (2000) J Immunol. , vol.165 , Issue.12 , pp. 6723-6730
    • Apolloni, E.1    Bronte, V.2    Mazzoni, A.3    Serafini, P.4    Cabrelle, A.5    Segal, D.M.6
  • 12
    • 54049134747 scopus 로고    scopus 로고
    • Subsets of myeloid-derived suppressor cells in tumor-bearing mice
    • 18832739 1:CAS:528:DC%2BD1cXhtF2hsL3I
    • Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J Immunol. 2008;181:5791-802.
    • (2008) J Immunol. , vol.181 , pp. 5791-5802
    • Youn, J.I.1    Nagaraj, S.2    Collazo, M.3    Gabrilovich, D.I.4
  • 13
    • 43249130187 scopus 로고    scopus 로고
    • Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell - Suppressive activity
    • 10.1182/blood-2007-07-099226 18272812 1:CAS:528:DC%2BD1cXkvFeisb4%3D
    • Movahedi K, Guilliams M, Van den Bossche J, Van den Bergh R, Gysemans C, Beschin A, et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell - suppressive activity. Blood. 2008;111(8):4233-44. doi: 10.1182/blood-2007-07-099226.
    • (2008) Blood , vol.111 , Issue.8 , pp. 4233-4244
    • Movahedi, K.1    Guilliams, M.2    Van Den Bossche, J.3    Van Den Bergh, R.4    Gysemans, C.5    Beschin, A.6
  • 14
    • 74249101123 scopus 로고    scopus 로고
    • Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF
    • 10.1002/eji.200939903 19941314 1:CAS:528:DC%2BC3cXktVCn
    • Dolcetti L, Peranzoni E, Ugel S, Marigo I, Fernandez Gomez A, Mesa C, et al. Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF. Eur J Immunol. 2010;40(1):22-35. doi: 10.1002/eji.200939903.
    • (2010) Eur J Immunol. , vol.40 , Issue.1 , pp. 22-35
    • Dolcetti, L.1    Peranzoni, E.2    Ugel, S.3    Marigo, I.4    Fernandez Gomez, A.5    Mesa, C.6
  • 15
    • 77951258918 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell heterogeneity and subset definition
    • 10.1016/j.coi.2010.01.021 20171075 1:CAS:528:DC%2BC3cXks1Srtr0%3D
    • Peranzoni E, Zilio S, Marigo I, Dolcetti L, Zanovello P, Mandruzzato S, et al. Myeloid-derived suppressor cell heterogeneity and subset definition. Curr Opin Immunol. 2010;22(2):238-44. doi: 10.1016/j.coi.2010.01.021.
    • (2010) Curr Opin Immunol. , vol.22 , Issue.2 , pp. 238-244
    • Peranzoni, E.1    Zilio, S.2    Marigo, I.3    Dolcetti, L.4    Zanovello, P.5    Mandruzzato, S.6
  • 16
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: Development, heterogeneity, and relationship with dendritic cells
    • 10.1146/annurev.immunol.021908.132557 19132917 1:CAS:528: DC%2BD1MXlsFSlt70%3D
    • Auffray C, Sieweke MH, Geissmann F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol. 2009;27:669-92. doi: 10.1146/annurev.immunol.021908.132557.
    • (2009) Annu Rev Immunol. , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 17
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • 10.1038/nri2506 19197294 1:CAS:528:DC%2BD1MXhsFeqsbw%3D
    • Gabrilovich DI, Nagaraj S. Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol. 2009;9(3):162-74. doi: 10.1038/nri2506.
    • (2009) Nat Rev Immunol. , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 18
    • 78649610261 scopus 로고    scopus 로고
    • IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function
    • 10.1002/eji.201041037 21110318 1:CAS:528:DC%2BC3cXhsVOktbbF
    • Elkabets M, Ribeiro VS, Dinarello CA, Ostrand-Rosenberg S, Di Santo JP, Apte RN, et al. IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol. 2010;40(12):3347-57. doi: 10.1002/eji.201041037.
    • (2010) Eur J Immunol. , vol.40 , Issue.12 , pp. 3347-3357
    • Elkabets, M.1    Ribeiro, V.S.2    Dinarello, C.A.3    Ostrand-Rosenberg, S.4    Di Santo, J.P.5    Apte, R.N.6
  • 19
    • 58149332680 scopus 로고    scopus 로고
    • Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma
    • 10.1158/1078-0432.CCR-08-0165 19088044 1:CAS:528:DC%2BD1cXhsV2it7jF
    • Kusmartsev S, Su Z, Heiser A, Dannull J, Eruslanov E, Kubler H, et al. Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma. Clin Cancer Res. 2008;14(24):8270-8. doi: 10.1158/1078-0432.CCR-08-0165.
    • (2008) Clin Cancer Res. , vol.14 , Issue.24 , pp. 8270-8278
    • Kusmartsev, S.1    Su, Z.2    Heiser, A.3    Dannull, J.4    Eruslanov, E.5    Kubler, H.6
  • 20
    • 60549088732 scopus 로고    scopus 로고
    • Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
    • 10.1158/0008-5472.CAN-08-1921 19201693 1:CAS:528:DC%2BD1MXhslynsb4%3D
    • Rodriguez PC, Ernstoff MS, Hernandez C, Atkins M, Zabaleta J, Sierra R, et al. Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res. 2009;69(4):1553-60. doi: 10.1158/0008-5472.CAN-08-1921.
    • (2009) Cancer Res. , vol.69 , Issue.4 , pp. 1553-1560
    • Rodriguez, P.C.1    Ernstoff, M.S.2    Hernandez, C.3    Atkins, M.4    Zabaleta, J.5    Sierra, R.6
  • 21
    • 0035874990 scopus 로고    scopus 로고
    • Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients
    • 11406548 1:CAS:528:DC%2BD3MXks1Grtbg%3D
    • Schmielau J, Finn OJ. Activated granulocytes and granulocyte-derived hydrogen peroxide are the underlying mechanism of suppression of T-cell function in advanced cancer patients. Cancer Res. 2001;61(12):4756-60.
    • (2001) Cancer Res. , vol.61 , Issue.12 , pp. 4756-4760
    • Schmielau, J.1    Finn, O.J.2
  • 22
    • 66949145484 scopus 로고    scopus 로고
    • Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells
    • 10.4049/jimmunol.0900092 19380816 1:CAS:528:DC%2BD1MXkslKhs7g%3D
    • Corzo CA, Cotter MJ, Cheng P, Cheng F, Kusmartsev S, Sotomayor E, et al. Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells. J Immunol. 2009;182(9):5693-701. doi: 10.4049/jimmunol. 0900092.
    • (2009) J Immunol. , vol.182 , Issue.9 , pp. 5693-5701
    • Corzo, C.A.1    Cotter, M.J.2    Cheng, P.3    Cheng, F.4    Kusmartsev, S.5    Sotomayor, E.6
  • 23
    • 85027923251 scopus 로고    scopus 로고
    • Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer
    • doi: 10.1038/ni.2526
    • Youn JI, Kumar V, Collazo M, Nefedova Y, Condamine T, Cheng P, et al. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nat Immunol. 2013. doi: 10.1038/ni.2526.
    • (2013) Nat Immunol.
    • Youn, J.I.1    Kumar, V.2    Collazo, M.3    Nefedova, Y.4    Condamine, T.5    Cheng, P.6
  • 24
    • 80053200887 scopus 로고    scopus 로고
    • Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer
    • 10.1002/ijc.26123 21480223 1:CAS:528:DC%2BC3MXhs1Cnsr7E
    • Eruslanov E, Neuberger M, Daurkin I, Perrin GQ, Algood C, Dahm P, et al. Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer. Int J Cancer. 2012;130(5):1109-19. doi: 10.1002/ijc.26123.
    • (2012) Int J Cancer. , vol.130 , Issue.5 , pp. 1109-1119
    • Eruslanov, E.1    Neuberger, M.2    Daurkin, I.3    Perrin, G.Q.4    Algood, C.5    Dahm, P.6
  • 25
    • 0032533159 scopus 로고    scopus 로고
    • Arginine metabolism: Nitric oxide and beyond
    • 9806879 1:CAS:528:DyaK1cXotVGltrs%3D
    • Wu G, Morris SM Jr. Arginine metabolism: nitric oxide and beyond. Biochem J. 1998;336(Pt 1):1-17.
    • (1998) Biochem J. , vol.336 , Issue.PART 1 , pp. 1-17
    • Wu, G.1    Morris, Jr.S.M.2
  • 26
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • 11577346 1:CAS:528:DC%2BD3MXnsVCisrs%3D
    • Bogdan C. Nitric oxide and the immune response. Nat Immunol. 2001;2(10):907-16.
    • (2001) Nat Immunol. , vol.2 , Issue.10 , pp. 907-916
    • Bogdan, C.1
  • 27
    • 4544309074 scopus 로고    scopus 로고
    • TCR zeta-chain downregulation: Curtailing an excessive inflammatory immune response
    • 15343367 1:CAS:528:DC%2BD2cXntFCmt7Y%3D
    • Baniyash M. TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response. Nat Rev Immunol. 2004;4(9):675-87.
    • (2004) Nat Rev Immunol. , vol.4 , Issue.9 , pp. 675-687
    • Baniyash, M.1
  • 28
    • 4143130091 scopus 로고    scopus 로고
    • Arginase i production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
    • 15313928 1:CAS:528:DC%2BD2cXmslaks70%3D
    • Rodriguez PC, Quiceno DG, Zabaleta J, Ortiz B, Zea AH, Piazuelo MB, et al. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses. Cancer Res. 2004;64(16):5839-49.
    • (2004) Cancer Res , vol.64 , Issue.16 , pp. 5839-5849
    • Rodriguez, P.C.1    Quiceno, D.G.2    Zabaleta, J.3    Ortiz, B.4    Zea, A.H.5    Piazuelo, M.B.6
  • 29
    • 0036291267 scopus 로고    scopus 로고
    • Overexpression of arginase i in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development
    • 12081826
    • de Jonge WJ, Hallemeesch MM, Kwikkers KL, Ruijter JM, de Gier-de Vries C, van Roon MA, et al. Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development. Am J Clin Nutr. 2002;76(1):128-40.
    • (2002) Am J Clin Nutr. , vol.76 , Issue.1 , pp. 128-140
    • De Jonge, W.J.1    Hallemeesch, M.M.2    Kwikkers, K.L.3    Ruijter, J.M.4    De Gier-De Vries, C.5    Van Roon, M.A.6
  • 30
    • 84866916560 scopus 로고    scopus 로고
    • Metabolism of l-arginine by myeloid-derived suppressor cells in cancer: Mechanisms of T cell suppression and therapeutic perspectives
    • 10.3109/08820139.2012.680634 23017138 1:CAS:528:DC%2BC38XhsVeiurrF
    • Raber P, Ochoa AC, Rodriguez PC. Metabolism of l-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol Invest. 2012;41(6-7):614-34. doi: 10.3109/08820139.2012.680634.
    • (2012) Immunol Invest. , vol.41 , Issue.6-7 , pp. 614-634
    • Raber, P.1    Ochoa, A.C.2    Rodriguez, P.C.3
  • 31
    • 33846933459 scopus 로고    scopus 로고
    • L-arginine availability regulates T-lymphocyte cell-cycle progression
    • 10.1182/blood-2006-06-031856 17023580 1:CAS:528:DC%2BD2sXjt1CgsLY%3D
    • Rodriguez PC, Quiceno DG, Ochoa AC. l-arginine availability regulates T-lymphocyte cell-cycle progression. Blood. 2007;109(4):1568-73. doi: 10.1182/blood-2006-06-031856.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1568-1573
    • Rodriguez, P.C.1    Quiceno, D.G.2    Ochoa, A.C.3
  • 32
    • 78149491757 scopus 로고    scopus 로고
    • L-arginine deprivation regulates cyclin D3 mRNA stability in human T cells by controlling HuR expression
    • 10.4049/jimmunol.1001224 20889542 1:CAS:528:DC%2BC3cXhtlWhsrvM
    • Rodriguez PC, Hernandez CP, Morrow K, Sierra R, Zabaleta J, Wyczechowska DD, et al. l-arginine deprivation regulates cyclin D3 mRNA stability in human T cells by controlling HuR expression. J Immunol. 2010;185(9):5198-204. doi: 10.4049/jimmunol.1001224.
    • (2010) J Immunol. , vol.185 , Issue.9 , pp. 5198-5204
    • Rodriguez, P.C.1    Hernandez, C.P.2    Morrow, K.3    Sierra, R.4    Zabaleta, J.5    Wyczechowska, D.D.6
  • 33
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: Enabling diversity with identity
    • 10.1038/nri3088 22025054 1:CAS:528:DC%2BC3MXhtlGks7vF
    • Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol. 2011;11(11):750-61. doi: 10.1038/nri3088.
    • (2011) Nat Rev Immunol. , vol.11 , Issue.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 34
    • 33745559710 scopus 로고    scopus 로고
    • The role of nitric oxide in tumour progression
    • 10.1038/nrc1910 16794635 1:CAS:528:DC%2BD28XmtFehu7Y%3D
    • Fukumura D, Kashiwagi S, Jain RK the role of nitric oxide in tumour progression. Nat Rev Cancer. 2006;6(7):521-34. doi: 10.1038/nrc1910.
    • (2006) Nat Rev Cancer. , vol.6 , Issue.7 , pp. 521-534
    • Fukumura, D.1    Kashiwagi, S.2    Jain, R.K.3
  • 35
    • 23444456772 scopus 로고    scopus 로고
    • Regulation of immune responses by l-arginine metabolism
    • 10.1038/nri1668 16056256 1:CAS:528:DC%2BD2MXmvVClsLc%3D
    • Bronte V, Zanovello P. Regulation of immune responses by l-arginine metabolism. Nat Rev Immunol. 2005;5(8):641-54. doi: 10.1038/nri1668.
    • (2005) Nat Rev Immunol. , vol.5 , Issue.8 , pp. 641-654
    • Bronte, V.1    Zanovello, P.2
  • 36
    • 0037080021 scopus 로고    scopus 로고
    • Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism
    • 11777962 1:CAS:528:DC%2BD38XksFWlsg%3D%3D
    • Mazzoni A, Bronte V, Visintin A, Spitzer JH, Apolloni E, Serafini P, et al. Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J Immunol. 2002;168(2):689-95.
    • (2002) J Immunol. , vol.168 , Issue.2 , pp. 689-695
    • Mazzoni, A.1    Bronte, V.2    Visintin, A.3    Spitzer, J.H.4    Apolloni, E.5    Serafini, P.6
  • 37
    • 0035937175 scopus 로고    scopus 로고
    • Activation of cGMP-dependent protein kinase Iβ inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells
    • 11073964 1:CAS:528:DC%2BD3MXhs1Kmtbc%3D
    • Fischer TA, Palmetshofer A, Gambaryan S, Butt E, Jassoy C, Walter U, et al. Activation of cGMP-dependent protein kinase Iβ inhibits interleukin 2 release and proliferation of T cell receptor-stimulated human peripheral T cells. J Biol Chem. 2001;276(8):5967-74.
    • (2001) J Biol Chem. , vol.276 , Issue.8 , pp. 5967-5974
    • Fischer, T.A.1    Palmetshofer, A.2    Gambaryan, S.3    Butt, E.4    Jassoy, C.5    Walter, U.6
  • 39
    • 0032526629 scopus 로고    scopus 로고
    • Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway
    • 9637481 1:CAS:528:DyaK1cXjvVWku74%3D
    • Bingisser RM, Tilbrook PA, Holt PG, Kees UR. Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. J Immunol. 1998;160(12):5729-34.
    • (1998) J Immunol. , vol.160 , Issue.12 , pp. 5729-5734
    • Bingisser, R.M.1    Tilbrook, P.A.2    Holt, P.G.3    Kees, U.R.4
  • 40
    • 0142148325 scopus 로고    scopus 로고
    • Nitric oxide regulation of human peripheral blood mononuclear cells: Critical time dependence and selectivity for cytokine versus chemokine expression
    • 14568959 1:CAS:528:DC%2BD3sXot1Cnur8%3D
    • Macphail SE, Gibney CA, Brooks BM, Booth CG, Flanagan BF, Coleman JW. Nitric oxide regulation of human peripheral blood mononuclear cells: critical time dependence and selectivity for cytokine versus chemokine expression. J Immunol. 2003;171(9):4809-15.
    • (2003) J Immunol. , vol.171 , Issue.9 , pp. 4809-4815
    • Macphail, S.E.1    Gibney, C.A.2    Brooks, B.M.3    Booth, C.G.4    Flanagan, B.F.5    Coleman, J.W.6
  • 42
    • 0018426597 scopus 로고
    • Microenvironmental arginine depletion by macrophages in vivo
    • 444403 1:CAS:528:DyaL3cXitVequw%3D%3D
    • Currie GA, Gyure L, Cifuentes L. Microenvironmental arginine depletion by macrophages in vivo. Br J Cancer. 1979;39(6):613-20.
    • (1979) Br J Cancer. , vol.39 , Issue.6 , pp. 613-620
    • Currie, G.A.1    Gyure, L.2    Cifuentes, L.3
  • 43
    • 33749425534 scopus 로고    scopus 로고
    • Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
    • 10.1172/JCI28828 17016559 1:CAS:528:DC%2BD28XhtVKgu7vF
    • Gallina G, Dolcetti L, Serafini P, De Santo C, Marigo I, Colombo MP, et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest. 2006;116(10):2777-90. doi: 10.1172/JCI28828.
    • (2006) J Clin Invest. , vol.116 , Issue.10 , pp. 2777-2790
    • Gallina, G.1    Dolcetti, L.2    Serafini, P.3    De Santo, C.4    Marigo, I.5    Colombo, M.P.6
  • 44
    • 18644370173 scopus 로고    scopus 로고
    • Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection
    • 15879104 1:CAS:528:DC%2BD2MXjvV2mt74%3D
    • Brys L, Beschin A, Raes G, Ghassabeh GH, Noel W, Brandt J, et al. Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J Immunol. 2005;174(10):6095-104.
    • (2005) J Immunol. , vol.174 , Issue.10 , pp. 6095-6104
    • Brys, L.1    Beschin, A.2    Raes, G.3    Ghassabeh, G.H.4    Noel, W.5    Brandt, J.6
  • 45
    • 20944434107 scopus 로고    scopus 로고
    • Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers
    • 10.1084/jem.20042028 15824085 1:CAS:528:DC%2BD2MXjs1Citb4%3D
    • Bronte V, Kasic T, Gri G, Gallana K, Borsellino G, Marigo I, et al. Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers. J Exp Med. 2005;201(8):1257-68. doi: 10.1084/jem.20042028.
    • (2005) J Exp Med. , vol.201 , Issue.8 , pp. 1257-1268
    • Bronte, V.1    Kasic, T.2    Gri, G.3    Gallana, K.4    Borsellino, G.5    Marigo, I.6
  • 46
    • 0037223634 scopus 로고    scopus 로고
    • Arginase 1 overexpression in psoriasis: Limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation
    • 12507903 1:CAS:528:DC%2BD3sXlsFyqtQ%3D%3D
    • Bruch-Gerharz D, Schnorr O, Suschek C, Beck KF, Pfeilschifter J, Ruzicka T, et al. Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation. Am J Pathol. 2003;162(1):203-11.
    • (2003) Am J Pathol. , vol.162 , Issue.1 , pp. 203-211
    • Bruch-Gerharz, D.1    Schnorr, O.2    Suschek, C.3    Beck, K.F.4    Pfeilschifter, J.5    Ruzicka, T.6
  • 47
    • 0038519365 scopus 로고    scopus 로고
    • L-arginine metabolism in myeloid cells controls T-lymphocyte functions
    • 12810105 1:CAS:528:DC%2BD3sXks1amsrc%3D
    • Bronte V, Serafini P, Mazzoni A, Segal DM, Zanovello P. l-arginine metabolism in myeloid cells controls T-lymphocyte functions. Trends Immunol. 2003;24(6):302-6.
    • (2003) Trends Immunol. , vol.24 , Issue.6 , pp. 302-306
    • Bronte, V.1    Serafini, P.2    Mazzoni, A.3    Segal, D.M.4    Zanovello, P.5
  • 48
    • 20144375187 scopus 로고    scopus 로고
    • Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination
    • 10.1073/pnas.0409783102 15753302
    • De Santo C, Serafini P, Marigo I, Dolcetti L, Bolla M, Del Soldato P, et al. Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination. Proc Natl Acad Sci USA. 2005;102(11):4185-90. doi: 10.1073/pnas.0409783102.
    • (2005) Proc Natl Acad Sci USA. , vol.102 , Issue.11 , pp. 4185-4190
    • De Santo, C.1    Serafini, P.2    Marigo, I.3    Dolcetti, L.4    Bolla, M.5    Del Soldato, P.6
  • 49
    • 33751531874 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
    • 10.1084/jem.20061104 17101732 1:CAS:528:DC%2BD28Xht12htLfL
    • Serafini P, Meckel K, Kelso M, Noonan K, Califano J, Koch W, et al. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med. 2006;203(12):2691-702. doi: 10.1084/jem.20061104.
    • (2006) J Exp Med. , vol.203 , Issue.12 , pp. 2691-2702
    • Serafini, P.1    Meckel, K.2    Kelso, M.3    Noonan, K.4    Califano, J.5    Koch, W.6
  • 50
    • 17044366637 scopus 로고    scopus 로고
    • STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion
    • 15814715 1:CAS:528:DC%2BD2MXivFKiurg%3D
    • Kusmartsev S, Gabrilovich DI. STAT1 signaling regulates tumor-associated macrophage-mediated T cell deletion. J Immunol. 2005;174(8):4880-91.
    • (2005) J Immunol. , vol.174 , Issue.8 , pp. 4880-4891
    • Kusmartsev, S.1    Gabrilovich, D.I.2
  • 51
    • 0032575598 scopus 로고    scopus 로고
    • Inducible nitric-oxide synthase generates superoxide from the reductase domain
    • 9712892 1:CAS:528:DyaK1cXlvValtbg%3D
    • Xia Y, Roman LJ, Masters BS, Zweier JL. Inducible nitric-oxide synthase generates superoxide from the reductase domain. J Biol Chem. 1998;273(35):22635-9.
    • (1998) J Biol Chem. , vol.273 , Issue.35 , pp. 22635-22639
    • Xia, Y.1    Roman, L.J.2    Masters, B.S.3    Zweier, J.L.4
  • 52
    • 0031002421 scopus 로고    scopus 로고
    • Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
    • 9192673 1:CAS:528:DyaK2sXktF2qsrc%3D
    • Xia Y, Zweier JL. Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proc Natl Acad Sci USA. 1997;94(13):6954-8.
    • (1997) Proc Natl Acad Sci USA. , vol.94 , Issue.13 , pp. 6954-6958
    • Xia, Y.1    Zweier, J.L.2
  • 53
    • 0037223170 scopus 로고    scopus 로고
    • IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice
    • 12496409 1:CAS:528:DC%2BD3sXhtFGqsA%3D%3D
    • Bronte V, Serafini P, De Santo C, Marigo I, Tosello V, Mazzoni A, et al. IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice. J Immunol. 2003;170(1):270-8.
    • (2003) J Immunol. , vol.170 , Issue.1 , pp. 270-278
    • Bronte, V.1    Serafini, P.2    De Santo, C.3    Marigo, I.4    Tosello, V.5    Mazzoni, A.6
  • 54
    • 34848861137 scopus 로고    scopus 로고
    • Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction
    • 10.1161/CIRCRESAHA.107.157727 17704205 1:CAS:528:DC%2BD2sXhtVOrsL%2FI
    • Santhanam L, Lim HK, Miriel V, Brown T, Patel M, Balanson S, et al. Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction. Circ Res. 2007;101(7):692-702. doi: 10.1161/CIRCRESAHA.107.157727.
    • (2007) Circ Res. , vol.101 , Issue.7 , pp. 692-702
    • Santhanam, L.1    Lim, H.K.2    Miriel, V.3    Brown, T.4    Patel, M.5    Balanson, S.6
  • 55
    • 0025882811 scopus 로고
    • Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones
    • 1680678 1:STN:280:DyaK38%2Fgslyltg%3D%3D
    • Gmunder H, Eck HP, Droge W. Low membrane transport activity for cystine in resting and mitogenically stimulated human lymphocyte preparations and human T cell clones. Eur J Biochem. 1991;201(1):113-7.
    • (1991) Eur J Biochem. , vol.201 , Issue.1 , pp. 113-117
    • Gmunder, H.1    Eck, H.P.2    Droge, W.3
  • 56
    • 0021215013 scopus 로고
    • Transport of cystine and cysteine in mammalian cells
    • 6383474 1:CAS:528:DyaL2cXls1Orsr4%3D
    • Bannai S. Transport of cystine and cysteine in mammalian cells. Biochim Biophys Acta. 1984;779(3):289-306.
    • (1984) Biochim Biophys Acta. , vol.779 , Issue.3 , pp. 289-306
    • Bannai, S.1
  • 57
    • 0028318891 scopus 로고
    • Thiol-mediated redox regulation of lymphocyte proliferation. Possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression
    • 8207197 1:CAS:528:DyaK2cXkvVSrurs%3D
    • Iwata S, Hori T, Sato N, Ueda-Taniguchi Y, Yamabe T, Nakamura H, et al. Thiol-mediated redox regulation of lymphocyte proliferation. Possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression. J Immunol. 1994;152(12):5633-42.
    • (1994) J Immunol. , vol.152 , Issue.12 , pp. 5633-5642
    • Iwata, S.1    Hori, T.2    Sato, N.3    Ueda-Taniguchi, Y.4    Yamabe, T.5    Nakamura, H.6
  • 58
    • 0025368350 scopus 로고
    • Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine
    • 2364441 1:STN:280:DyaK3czgsV2nuw%3D%3D
    • Gmunder H, Eck HP, Benninghoff B, Roth S, Droge W. Macrophages regulate intracellular glutathione levels of lymphocytes. Evidence for an immunoregulatory role of cysteine. Cell Immunol. 1990;129(1):32-46.
    • (1990) Cell Immunol. , vol.129 , Issue.1 , pp. 32-46
    • Gmunder, H.1    Eck, H.P.2    Benninghoff, B.3    Roth, S.4    Droge, W.5
  • 59
    • 75149123468 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
    • 10.1158/0008-5472.CAN-09-2587 20028852 1:CAS:528:DC%2BC3cXltVaj
    • Srivastava MK, Sinha P, Clements VK, Rodriguez P, Ostrand-Rosenberg S. Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res. 2010;70(1):68-77. doi: 10.1158/0008-5472.CAN-09-2587.
    • (2010) Cancer Res. , vol.70 , Issue.1 , pp. 68-77
    • Srivastava, M.K.1    Sinha, P.2    Clements, V.K.3    Rodriguez, P.4    Ostrand-Rosenberg, S.5
  • 60
    • 0029841427 scopus 로고    scopus 로고
    • Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses
    • 8917554 1:CAS:528:DyaK28XmvV2rtbo%3D
    • Otsuji M, Kimura Y, Aoe T, Okamoto Y, Saito T. Oxidative stress by tumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cell receptor complex and antigen-specific T-cell responses. Proc Natl Acad Sci USA. 1996;93(23):13119-24.
    • (1996) Proc Natl Acad Sci USA. , vol.93 , Issue.23 , pp. 13119-13124
    • Otsuji, M.1    Kimura, Y.2    Aoe, T.3    Okamoto, Y.4    Saito, T.5
  • 61
    • 0029828089 scopus 로고    scopus 로고
    • Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer
    • 9816136 1:STN:280:DyaK1M%2FjsFaitA%3D%3D
    • Kono K, Ressing ME, Brandt RM, Melief CJ, Potkul RK, Andersson B, et al. Decreased expression of signal-transducing zeta chain in peripheral T cells and natural killer cells in patients with cervical cancer. Clin Cancer Res. 1996;2(11):1825-8.
    • (1996) Clin Cancer Res. , vol.2 , Issue.11 , pp. 1825-1828
    • Kono, K.1    Ressing, M.E.2    Brandt, R.M.3    Melief, C.J.4    Potkul, R.K.5    Andersson, B.6
  • 62
    • 0030048536 scopus 로고    scopus 로고
    • Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity
    • 8647210 1:CAS:528:DyaK28Xks1egtr0%3D
    • Kono K, Salazar-Onfray F, Petersson M, Hansson J, Masucci G, Wasserman K, et al. Hydrogen peroxide secreted by tumor-derived macrophages down-modulates signal-transducing zeta molecules and inhibits tumor-specific T cell-and natural killer cell-mediated cytotoxicity. Eur J Immunol. 1996;26(6):1308-13.
    • (1996) Eur J Immunol. , vol.26 , Issue.6 , pp. 1308-1313
    • Kono, K.1    Salazar-Onfray, F.2    Petersson, M.3    Hansson, J.4    Masucci, G.5    Wasserman, K.6
  • 63
    • 84855301911 scopus 로고    scopus 로고
    • Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice
    • 10.1189/jlb.0311177 21954284 1:CAS:528:DC%2BC38Xmtlamtg%3D%3D
    • Youn JI, Collazo M, Shalova IN, Biswas SK, Gabrilovich DI. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. J Leukoc Biol. 2012;91(1):167-81. doi: 10.1189/jlb.0311177.
    • (2012) J Leukoc Biol. , vol.91 , Issue.1 , pp. 167-181
    • Youn, J.I.1    Collazo, M.2    Shalova, I.N.3    Biswas, S.K.4    Gabrilovich, D.I.5
  • 64
    • 79951823584 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties
    • 10.1189/jlb.0310162 21106641 1:CAS:528:DC%2BC3MXkvVWqs7Y%3D
    • Brandau S, Trellakis S, Bruderek K, Schmaltz D, Steller G, Elian M, et al. Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. J Leukoc Biol. 2011;89(2):311-7. doi: 10.1189/jlb.0310162.
    • (2011) J Leukoc Biol. , vol.89 , Issue.2 , pp. 311-317
    • Brandau, S.1    Trellakis, S.2    Bruderek, K.3    Schmaltz, D.4    Steller, G.5    Elian, M.6
  • 65
    • 84866358651 scopus 로고    scopus 로고
    • Molecular pathways: Tumor-infiltrating myeloid cells and reactive oxygen species in regulation of tumor microenvironment
    • 10.1158/1078-0432.CCR-11-2939 22718858 1:CAS:528:DC%2BC38Xhtl2lt77P
    • Lu T, Gabrilovich DI. Molecular pathways: tumor-infiltrating myeloid cells and reactive oxygen species in regulation of tumor microenvironment. Clin Cancer Res. 2012;18(18):4877-82. doi: 10.1158/1078-0432.CCR-11-2939.
    • (2012) Clin Cancer Res. , vol.18 , Issue.18 , pp. 4877-4882
    • Lu, T.1    Gabrilovich, D.I.2
  • 66
    • 0346100520 scopus 로고    scopus 로고
    • Peroxynitrite reactivity with amino acids and proteins
    • 10.1007/s00726-003-0018-8 14661092 1:CAS:528:DC%2BD3sXpsFOntb4%3D
    • Alvarez B, Radi R. Peroxynitrite reactivity with amino acids and proteins. Amino Acids. 2003;25(3-4):295-311. doi: 10.1007/s00726-003-0018-8.
    • (2003) Amino Acids. , vol.25 , Issue.3-4 , pp. 295-311
    • Alvarez, B.1    Radi, R.2
  • 67
    • 34447118098 scopus 로고    scopus 로고
    • Altered recognition of antigen is a mechanism of CD8(+) T cell tolerance in cancer
    • 17603493 1:CAS:528:DC%2BD2sXnsFWmt7w%3D
    • Nagaraj S, Gupta K, Pisarev V, Kinarsky L, Sherman S, Kang L, et al. Altered recognition of antigen is a mechanism of CD8(+) T cell tolerance in cancer. Nat Med. 2007;13(7):828-35.
    • (2007) Nat Med. , vol.13 , Issue.7 , pp. 828-835
    • Nagaraj, S.1    Gupta, K.2    Pisarev, V.3    Kinarsky, L.4    Sherman, S.5    Kang, L.6
  • 68
    • 80054694464 scopus 로고    scopus 로고
    • Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells
    • 10.1084/jem.20101956 21930770 1:CAS:528:DC%2BC3MXht1KjsbnI
    • Molon B, Ugel S, Del Pozzo F, Soldani C, Zilio S, Avella D, et al. Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells. J Exp Med. 2011;208(10):1949-62. doi: 10.1084/jem.20101956.
    • (2011) J Exp Med. , vol.208 , Issue.10 , pp. 1949-1962
    • Molon, B.1    Ugel, S.2    Del Pozzo, F.3    Soldani, C.4    Zilio, S.5    Avella, D.6
  • 69
    • 80053421470 scopus 로고    scopus 로고
    • Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice
    • 10.1172/JCI45862 21911941 1:CAS:528:DC%2BC3MXht12ht7nF
    • Lu T, Ramakrishnan R, Altiok S, Youn JI, Cheng P, Celis E, et al. Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. J Clin Invest. 2011;121(10):4015-29. doi: 10.1172/JCI45862.
    • (2011) J Clin Invest. , vol.121 , Issue.10 , pp. 4015-4029
    • Lu, T.1    Ramakrishnan, R.2    Altiok, S.3    Youn, J.I.4    Cheng, P.5    Celis, E.6
  • 70
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • 10.1158/0008-5472.CAN-07-6621 18593947 1:CAS:528:DC%2BD1cXnvFyjur4%3D
    • Serafini P, Mgebroff S, Noonan K, Borrello I. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 2008;68(13):5439-49. doi: 10.1158/0008-5472.CAN-07-6621.
    • (2008) Cancer Res. , vol.68 , Issue.13 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 71
    • 75149179545 scopus 로고    scopus 로고
    • Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer
    • 10.1158/0008-5472.CAN-09-1882 19996287 1:CAS:528:DC%2BC3cXltVan
    • Pan PY, Ma G, Weber KJ, Ozao-Choy J, Wang G, Yin B, et al. Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer. Cancer Res. 2010;70(1):99-108. doi: 10.1158/0008-5472.CAN-09-1882.
    • (2010) Cancer Res. , vol.70 , Issue.1 , pp. 99-108
    • Pan, P.Y.1    Ma, G.2    Weber, K.J.3    Ozao-Choy, J.4    Wang, G.5    Yin, B.6
  • 72
    • 13544256627 scopus 로고    scopus 로고
    • Cytokine expanded myeloid precursors function as regulatory antigen-presenting cells and promote tolerance through IL-10-producing regulatory T cells
    • 15699110 1:CAS:528:DC%2BD2MXhtV2ku7c%3D
    • MacDonald KP, Rowe V, Clouston AD, Welply JK, Kuns RD, Ferrara JL, et al. Cytokine expanded myeloid precursors function as regulatory antigen-presenting cells and promote tolerance through IL-10-producing regulatory T cells. J Immunol. 2005;174(4):1841-50.
    • (2005) J Immunol. , vol.174 , Issue.4 , pp. 1841-1850
    • Macdonald, K.P.1    Rowe, V.2    Clouston, A.D.3    Welply, J.K.4    Kuns, R.D.5    Ferrara, J.L.6
  • 73
    • 80051777041 scopus 로고    scopus 로고
    • In vivo induction of myeloid suppressor cells and CD4(+) Foxp3(+) T regulatory cells prolongs skin allograft survival in mice
    • 10.3727/096368910X540621 21054938 1:STN:280:DC%2BC3MjnvV2ksQ%3D%3D
    • Adeegbe D, Serafini P, Bronte V, Zoso A, Ricordi C, Inverardi L. In vivo induction of myeloid suppressor cells and CD4(+) Foxp3(+) T regulatory cells prolongs skin allograft survival in mice. Cell Transplant. 2011;20(6):941-54. doi: 10.3727/096368910X540621.
    • (2011) Cell Transplant. , vol.20 , Issue.6 , pp. 941-954
    • Adeegbe, D.1    Serafini, P.2    Bronte, V.3    Zoso, A.4    Ricordi, C.5    Inverardi, L.6
  • 74
    • 25844504654 scopus 로고    scopus 로고
    • Tumor cells convert immature myeloid dendritic cells into TGF-β - Secreting cells inducing CD4+ CD25+ regulatory T cell proliferation
    • 16186184 1:CAS:528:DC%2BD2MXhtVygt73F
    • Ghiringhelli F, Puig PE, Roux S, Parcellier A, Schmitt E, Solary E, et al. Tumor cells convert immature myeloid dendritic cells into TGF-β - secreting cells inducing CD4+ CD25+ regulatory T cell proliferation. J Exp Med. 2005;202(7):919-29.
    • (2005) J Exp Med. , vol.202 , Issue.7 , pp. 919-929
    • Ghiringhelli, F.1    Puig, P.E.2    Roux, S.3    Parcellier, A.4    Schmitt, E.5    Solary, E.6
  • 75
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+ CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • 10.1158/0008-5472.CAN-05-1299 16424049 1:CAS:528:DC%2BD28XlsFOgug%3D%3D
    • Huang B, Pan PY, Li Q, Sato AI, Levy DE, Bromberg J, et al. Gr-1+ CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 2006;66(2):1123-31. doi: 10.1158/0008-5472.CAN-05-1299.
    • (2006) Cancer Res. , vol.66 , Issue.2 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6
  • 76
    • 46049098560 scopus 로고    scopus 로고
    • A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+) CD25(+) Foxp3(+) T cells
    • 10.1053/j.gastro.2008.03.020 18485901 1:CAS:528:DC%2BD1cXps1Wltb0%3D
    • Hoechst B, Ormandy LA, Ballmaier M, Lehner F, Kruger C, Manns MP, et al. A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+) CD25(+) Foxp3(+) T cells. Gastroenterology. 2008;135(1):234-43. doi: 10.1053/j.gastro.2008.03.020.
    • (2008) Gastroenterology. , vol.135 , Issue.1 , pp. 234-243
    • Hoechst, B.1    Ormandy, L.A.2    Ballmaier, M.3    Lehner, F.4    Kruger, C.5    Manns, M.P.6
  • 77
    • 79959271214 scopus 로고    scopus 로고
    • Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells
    • 10.1182/blood-2010-11-317321 21493801 1:CAS:528:DC%2BC3MXot1Gqtr8%3D
    • Hoechst B, Gamrekelashvili J, Manns MP, Greten TF, Korangy F. Plasticity of human Th17 cells and iTregs is orchestrated by different subsets of myeloid cells. Blood. 2011;117(24):6532-41. doi: 10.1182/blood-2010-11-317321.
    • (2011) Blood. , vol.117 , Issue.24 , pp. 6532-6541
    • Hoechst, B.1    Gamrekelashvili, J.2    Manns, M.P.3    Greten, T.F.4    Korangy, F.5
  • 78
    • 0034548004 scopus 로고    scopus 로고
    • Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-γ
    • 11086037 1:CAS:528:DC%2BD3cXosFOitbw%3D
    • Cauley LS, Miller EE, Yen M, Swain SL. Superantigen-induced CD4 T cell tolerance mediated by myeloid cells and IFN-γ. J Immunol. 2000;165(11):6056-66.
    • (2000) J Immunol. , vol.165 , Issue.11 , pp. 6056-6066
    • Cauley, L.S.1    Miller, E.E.2    Yen, M.3    Swain, S.L.4
  • 79
    • 31344474166 scopus 로고    scopus 로고
    • Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
    • 10.1016/j.semcancer.2005.07.005 16168663 1:CAS:528:DC%2BD28XotVCmuw%3D%3D
    • Serafini P, Borrello I, Bronte V. Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol. 2006;16(1):53-65. doi: 10.1016/j.semcancer.2005.07.005.
    • (2006) Semin Cancer Biol. , vol.16 , Issue.1 , pp. 53-65
    • Serafini, P.1    Borrello, I.2    Bronte, V.3
  • 80
    • 4344590947 scopus 로고    scopus 로고
    • High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells
    • 10.1158/0008-5472.CAN-04-0757 15342423 1:CAS:528:DC%2BD2cXntFClt7k%3D
    • Serafini P, Carbley R, Noonan KA, Tan G, Bronte V, Borrello I. High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res. 2004;64(17):6337-43. doi: 10.1158/0008-5472.CAN-04-0757.
    • (2004) Cancer Res. , vol.64 , Issue.17 , pp. 6337-6343
    • Serafini, P.1    Carbley, R.2    Noonan, K.A.3    Tan, G.4    Bronte, V.5    Borrello, I.6
  • 81
    • 33847258205 scopus 로고    scopus 로고
    • Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients
    • Parmiani G, Castelli C, Pilla L, Santinami M, Colombo MP, Rivoltini L. Opposite immune functions of GM-CSF administered as vaccine adjuvant in cancer patients. Ann Oncol. 2007;18(2):226-32.
    • (2007) Ann Oncol , vol.18 , Issue.2 , pp. 226-232
    • Parmiani, G.1    Castelli, C.2    Pilla, L.3    Santinami, M.4    Colombo, M.P.5    Rivoltini, L.6
  • 82
    • 0029070112 scopus 로고
    • IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases
    • 7730632 1:CAS:528:DyaK2MXlsVyktL4%3D
    • Bronte V, Tsung K, Rao JB, Chen PW, Wang M, Rosenberg SA, et al. IL-2 enhances the function of recombinant poxvirus-based vaccines in the treatment of established pulmonary metastases. J Immunol. 1995;154(10):5282-92.
    • (1995) J Immunol. , vol.154 , Issue.10 , pp. 5282-5292
    • Bronte, V.1    Tsung, K.2    Rao, J.B.3    Chen, P.W.4    Wang, M.5    Rosenberg, S.A.6
  • 83
    • 0032533478 scopus 로고    scopus 로고
    • Apoptotic death of CD8+ T lymphocytes after immunization: Induction of a suppressive population of Mac-1+/Gr-1+ cells
    • 9820504 1:CAS:528:DyaK1cXnsVOrtb0%3D
    • Bronte V, Wang M, Overwijk WW, Surman DR, Pericle F, Rosenberg SA, et al. Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells. J Immunol. 1998;161(10):5313-20.
    • (1998) J Immunol. , vol.161 , Issue.10 , pp. 5313-5320
    • Bronte, V.1    Wang, M.2    Overwijk, W.W.3    Surman, D.R.4    Pericle, F.5    Rosenberg, S.A.6
  • 84
    • 79952822608 scopus 로고    scopus 로고
    • A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma
    • 10.2119/molmed.2010.00178 21085745 1:CAS:528:DC%2BC3MXjvFWgtb0%3D
    • Cuenca AG, Delano MJ, Kelly-Scumpia KM, Moreno C, Scumpia PO, Laface DM, et al. A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol Med. 2011;17(3-4):281-92. doi: 10.2119/molmed.2010.00178.
    • (2011) Mol Med. , vol.17 , Issue.3-4 , pp. 281-292
    • Cuenca, A.G.1    Delano, M.J.2    Kelly-Scumpia, K.M.3    Moreno, C.4    Scumpia, P.O.5    Laface, D.M.6
  • 85
    • 77951926024 scopus 로고    scopus 로고
    • Cutting edge: Bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling
    • 10.4049/jimmunol.0903652 20130216 1:CAS:528:DC%2BC3cXitV2ksr8%3D
    • Scumpia PO, Kelly-Scumpia KM, Delano MJ, Weinstein JS, Cuenca AG, Al-Quran S, et al. Cutting edge: bacterial infection induces hematopoietic stem and progenitor cell expansion in the absence of TLR signaling. J Immunol. 2010;184(5):2247-51. doi: 10.4049/jimmunol.0903652.
    • (2010) J Immunol. , vol.184 , Issue.5 , pp. 2247-2251
    • Scumpia, P.O.1    Kelly-Scumpia, K.M.2    Delano, M.J.3    Weinstein, J.S.4    Cuenca, A.G.5    Al-Quran, S.6
  • 86
    • 5444241502 scopus 로고    scopus 로고
    • Diminished bacterial clearance is associated with decreased IL-12 and interferon-gamma production but a sustained proinflammatory response in a murine model of postseptic immunosuppression
    • 15087817 1:CAS:528:DC%2BD2cXkt1Shsb4%3D
    • Murphey ED, Lin CY, McGuire RW, Toliver-Kinsky T, Herndon DN, Sherwood ER. Diminished bacterial clearance is associated with decreased IL-12 and interferon-gamma production but a sustained proinflammatory response in a murine model of postseptic immunosuppression. Shock. 2004;21(5):415-25.
    • (2004) Shock. , vol.21 , Issue.5 , pp. 415-425
    • Murphey, E.D.1    Lin, C.Y.2    McGuire, R.W.3    Toliver-Kinsky, T.4    Herndon, D.N.5    Sherwood, E.R.6
  • 87
    • 32044439372 scopus 로고    scopus 로고
    • CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress
    • 16455964 1:CAS:528:DC%2BD28XpvV2nsg%3D%3D
    • Makarenkova VP, Bansal V, Matta BM, Perez LA, Ochoa JB. CD11b+/Gr-1+ myeloid suppressor cells cause T cell dysfunction after traumatic stress. J Immunol. 2006;176(4):2085-94.
    • (2006) J Immunol. , vol.176 , Issue.4 , pp. 2085-2094
    • Makarenkova, V.P.1    Bansal, V.2    Matta, B.M.3    Perez, L.A.4    Ochoa, J.B.5
  • 88
    • 77954399377 scopus 로고    scopus 로고
    • Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function
    • 10.1084/jem.20091474 20530204 1:CAS:528:DC%2BC3cXovFaktLY%3D
    • Sander LE, Sackett SD, Dierssen U, Beraza N, Linke RP, Muller M, et al. Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function. J Exp Med. 2010;207(7):1453-64. doi: 10.1084/jem.20091474.
    • (2010) J Exp Med. , vol.207 , Issue.7 , pp. 1453-1464
    • Sander, L.E.1    Sackett, S.D.2    Dierssen, U.3    Beraza, N.4    Linke, R.P.5    Muller, M.6
  • 89
    • 54549089856 scopus 로고    scopus 로고
    • Overexpression of interleukin-1β induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
    • 10.1016/j.ccr.2008.10.011 18977329 1:CAS:528:DC%2BD1cXhtlOjsLrP
    • Tu S, Bhagat G, Cui G, Takaishi S, Kurt-Jones EA, Rickman B, et al. Overexpression of interleukin-1β induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice. Cancer Cell. 2008;14(5):408-19. doi: 10.1016/j.ccr.2008.10.011.
    • (2008) Cancer Cell. , vol.14 , Issue.5 , pp. 408-419
    • Tu, S.1    Bhagat, G.2    Cui, G.3    Takaishi, S.4    Kurt-Jones, E.A.5    Rickman, B.6
  • 90
    • 84868629269 scopus 로고    scopus 로고
    • TNF signaling drives myeloid-derived suppressor cell accumulation
    • 10.1172/JCI64115 23064360 1:CAS:528:DC%2BC38Xhs1CisL%2FP
    • Zhao X, Rong L, Zhao X, Li X, Liu X, Deng J, et al. TNF signaling drives myeloid-derived suppressor cell accumulation. J Clin Investig. 2012;122(11):4094-104. doi: 10.1172/JCI64115.
    • (2012) J Clin Investig. , vol.122 , Issue.11 , pp. 4094-4104
    • Zhao, X.1    Rong, L.2    Zhao, X.3    Li, X.4    Liu, X.5    Deng, J.6
  • 91
    • 29644442445 scopus 로고    scopus 로고
    • Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression
    • 16365420 1:CAS:528:DC%2BD2MXhtlagtL7I
    • Bunt SK, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S. Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J Immunol. 2006;176(1):284-90.
    • (2006) J Immunol. , vol.176 , Issue.1 , pp. 284-290
    • Bunt, S.K.1    Sinha, P.2    Clements, V.K.3    Leips, J.4    Ostrand-Rosenberg, S.5
  • 92
    • 84863012062 scopus 로고    scopus 로고
    • Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species
    • 10.1002/hep.24700 21953144 1:CAS:528:DC%2BC38Xht1yqurY%3D
    • Tacke RS, Lee HC, Goh C, Courtney J, Polyak SJ, Rosen HR, et al. Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology. 2012;55(2):343-53. doi: 10.1002/hep.24700.
    • (2012) Hepatology , vol.55 , Issue.2 , pp. 343-353
    • Tacke, R.S.1    Lee, H.C.2    Goh, C.3    Courtney, J.4    Polyak, S.J.5    Rosen, H.R.6
  • 93
    • 84878017037 scopus 로고    scopus 로고
    • Clinical significance and functional studies of myeloid-derived suppressor cells in chronic hepatitis C patients
    • 10.1007/s10875-012-9861-2 23354838 1:CAS:528:DC%2BC3sXmsFGktr4%3D
    • Cai W, Qin A, Guo P, Yan D, Hu F, Yang Q, et al. Clinical significance and functional studies of myeloid-derived suppressor cells in chronic hepatitis C patients. J Clin Immunol. 2013;33(4):798-808. doi: 10.1007/s10875-012-9861-2.
    • (2013) J Clin Immunol. , vol.33 , Issue.4 , pp. 798-808
    • Cai, W.1    Qin, A.2    Guo, P.3    Yan, D.4    Hu, F.5    Yang, Q.6
  • 94
    • 84873049826 scopus 로고    scopus 로고
    • Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals
    • 10.1128/JVI.01759-12 23152536 1:CAS:528:DC%2BC3sXltV2isbk%3D
    • Qin A, Cai W, Pan T, Wu K, Yang Q, Wang N, et al. Expansion of monocytic myeloid-derived suppressor cells dampens T cell function in HIV-1-seropositive individuals. J Virol. 2013;87(3):1477-90. doi: 10.1128/JVI.01759-12.
    • (2013) J Virol. , vol.87 , Issue.3 , pp. 1477-1490
    • Qin, A.1    Cai, W.2    Pan, T.3    Wu, K.4    Yang, Q.5    Wang, N.6
  • 95
    • 84879789529 scopus 로고    scopus 로고
    • Poly(I:C) induce bone marrow precursor cells into myeloid-derived suppressor cells
    • 10.1007/s11010-011-0982-3 21744070 1:CAS:528:DC%2BC3MXhtlOntrfJ
    • Liu C, Zhang C, Lu H, Cai J, Wang Z, Chen J, et al. Poly(I:C) induce bone marrow precursor cells into myeloid-derived suppressor cells. Mol Cell Biochem. 2011;358(1-2):317-23. doi: 10.1007/s11010-011-0982-3.
    • (2011) Mol Cell Biochem. , vol.358 , Issue.1-2 , pp. 317-323
    • Liu, C.1    Zhang, C.2    Lu, H.3    Cai, J.4    Wang, Z.5    Chen, J.6
  • 96
    • 84864810354 scopus 로고    scopus 로고
    • NK cell response to vaccinia virus is regulated by myeloid-derived suppressor cells
    • 10.4049/jimmunol.1200584 22798671 1:CAS:528:DC%2BC38XhtFaqsLnN
    • Fortin C, Huang X, Yang Y. NK cell response to vaccinia virus is regulated by myeloid-derived suppressor cells. J Immunol. 2012;189(4):1843-9. doi: 10.4049/jimmunol.1200584.
    • (2012) J Immunol. , vol.189 , Issue.4 , pp. 1843-1849
    • Fortin, C.1    Huang, X.2    Yang, Y.3
  • 97
    • 56549105942 scopus 로고    scopus 로고
    • Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations
    • 10.1016/j.jaut.2008.08.006 18838247 1:CAS:528:DC%2BD1cXhsVeksrzI
    • Kerr EC, Raveney BJ, Copland DA, Dick AD, Nicholson LB. Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. J Autoimmun. 2008;31(4):354-61. doi: 10.1016/j.jaut.2008.08.006.
    • (2008) J Autoimmun. , vol.31 , Issue.4 , pp. 354-361
    • Kerr, E.C.1    Raveney, B.J.2    Copland, D.A.3    Dick, A.D.4    Nicholson, L.B.5
  • 98
    • 84878285077 scopus 로고    scopus 로고
    • Inflammatory cells of immunosuppressive phenotypes in oral lichen planus have a proinflammatory pattern of expression and are associated with clinical parameters
    • 10.1007/s00784-012-0814-1 22893035
    • Vered M, Furth E, Shalev Y, Dayan D. Inflammatory cells of immunosuppressive phenotypes in oral lichen planus have a proinflammatory pattern of expression and are associated with clinical parameters. Clin Oral Investig. 2013;17(5):1365-73. doi: 10.1007/s00784-012-0814-1.
    • (2013) Clin Oral Investig. , vol.17 , Issue.5 , pp. 1365-1373
    • Vered, M.1    Furth, E.2    Shalev, Y.3    Dayan, D.4
  • 99
    • 77957932965 scopus 로고    scopus 로고
    • Type 1 T helper cells induce the accumulation of myeloid-derived suppressor cells in the inflamed Tgfb1 knockout mouse liver
    • 10.1002/hep.23841 20803559 1:CAS:528:DC%2BC3cXhtlejsrjF
    • Cripps JG, Wang J, Maria A, Blumenthal I, Gorham JD. Type 1 T helper cells induce the accumulation of myeloid-derived suppressor cells in the inflamed Tgfb1 knockout mouse liver. Hepatology. 2010;52(4):1350-9. doi: 10.1002/hep.23841.
    • (2010) Hepatology. , vol.52 , Issue.4 , pp. 1350-1359
    • Cripps, J.G.1    Wang, J.2    Maria, A.3    Blumenthal, I.4    Gorham, J.D.5
  • 100
    • 73349118789 scopus 로고    scopus 로고
    • Innate immune CD11b+ Gr-1+ cells, suppressor cells, affect the immune response during Theiler's virus-induced demyelinating disease
    • 10.4049/jimmunol.0902193 19890055 1:CAS:528:DC%2BD1MXhsVehsLfO
    • Bowen JL, Olson JK. Innate immune CD11b+ Gr-1+ cells, suppressor cells, affect the immune response during Theiler's virus-induced demyelinating disease. J Immunol. 2009;183(11):6971-80. doi: 10.4049/jimmunol.0902193.
    • (2009) J Immunol. , vol.183 , Issue.11 , pp. 6971-6980
    • Bowen, J.L.1    Olson, J.K.2
  • 101
    • 51249105349 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells in inflammatory bowel disease: A new immunoregulatory pathway
    • 81 e1-e5. doi: 10.1053/j.gastro.2008.06.032
    • Haile LA, von Wasielewski R, Gamrekelashvili J, Kruger C, Bachmann O, Westendorf AM, et al. Myeloid-derived suppressor cells in inflammatory bowel disease: a new immunoregulatory pathway. Gastroenterology. 2008;135(3):871-81, 81 e1-e5. doi: 10.1053/j.gastro.2008.06.032.
    • (2008) Gastroenterology , vol.135 , Issue.3 , pp. 871-881
    • Haile, L.A.1    Von Wasielewski, R.2    Gamrekelashvili, J.3    Kruger, C.4    Bachmann, O.5    Westendorf, A.M.6
  • 102
    • 84874472017 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlated negatively with Th17 cells in patients with rheumatoid arthritis
    • 10.3109/03009742.2012.716450 23126644 1:STN:280:DC%2BC3s7gvFalsQ%3D%3D
    • Jiao Z, Hua S, Wang W, Wang H, Gao J, Wang X. Increased circulating myeloid-derived suppressor cells correlated negatively with Th17 cells in patients with rheumatoid arthritis. Scand J Rheumatol. 2013;42(2):85-90. doi: 10.3109/03009742.2012.716450.
    • (2013) Scand J Rheumatol. , vol.42 , Issue.2 , pp. 85-90
    • Jiao, Z.1    Hua, S.2    Wang, W.3    Wang, H.4    Gao, J.5    Wang, X.6
  • 103
    • 84890313690 scopus 로고    scopus 로고
    • Differential effects of smoking and COPD upon circulating myeloid derived suppressor cells
    • doi: 10.1016/j.rmed.2013.08.002
    • Scrimini S, Pons J, Agusti A, Soriano JB, Cosio BG, Torrecilla JA, et al. Differential effects of smoking and COPD upon circulating myeloid derived suppressor cells. Respiratory medicine. 2013. doi: 10.1016/j.rmed.2013.08.002.
    • (2013) Respiratory Medicine
    • Scrimini, S.1    Pons, J.2    Agusti, A.3    Soriano, J.B.4    Cosio, B.G.5    Torrecilla, J.A.6
  • 104
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • 10.1016/j.cell.2010.01.025 20303878 1:CAS:528:DC%2BC3cXlsVSgu7g%3D
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell. 2010;140(6):883-99. doi: 10.1016/j.cell.2010.01.025.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 105
    • 84857141296 scopus 로고    scopus 로고
    • Cancer-related inflammation: Common themes and therapeutic opportunities
    • 10.1016/j.semcancer.2011.12.005 22210179 1:CAS:528:DC%2BC38XisFGms74%3D
    • Balkwill FR, Mantovani A. Cancer-related inflammation: common themes and therapeutic opportunities. Semin Cancer Biol. 2012;22(1):33-40. doi: 10.1016/j.semcancer.2011.12.005.
    • (2012) Semin Cancer Biol. , vol.22 , Issue.1 , pp. 33-40
    • Balkwill, F.R.1    Mantovani, A.2
  • 106
    • 46749127004 scopus 로고    scopus 로고
    • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
    • 10.1172/JCI35073 18521188 1:CAS:528:DC%2BD1cXot1OntLg%3D
    • Meira LB, Bugni JM, Green SL, Lee CW, Pang B, Borenshtein D, et al. DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice. J Clin Investig. 2008;118(7):2516-25. doi: 10.1172/JCI35073.
    • (2008) J Clin Investig. , vol.118 , Issue.7 , pp. 2516-2525
    • Meira, L.B.1    Bugni, J.M.2    Green, S.L.3    Lee, C.W.4    Pang, B.5    Borenshtein, D.6
  • 107
    • 44249085373 scopus 로고    scopus 로고
    • Periodontal diseases and cancer
    • 10.1016/S1470-2045(08)70138-4 18510985
    • Migliorati CA. Periodontal diseases and cancer. Lancet Oncol. 2008;9(6):510-2. doi: 10.1016/S1470-2045(08)70138-4.
    • (2008) Lancet Oncol. , vol.9 , Issue.6 , pp. 510-512
    • Migliorati, C.A.1
  • 108
    • 84883133097 scopus 로고    scopus 로고
    • Inflammation in the context of oral cancer
    • 10.1016/j.oraloncology.2013.07.003 23910564 1:CAS:528:DC%2BC3sXht1emtr3L
    • Feller L, Altini M, Lemmer J. Inflammation in the context of oral cancer. Oral Oncol. 2013;49(9):887-92. doi: 10.1016/j.oraloncology.2013.07.003.
    • (2013) Oral Oncol. , vol.49 , Issue.9 , pp. 887-892
    • Feller, L.1    Altini, M.2    Lemmer, J.3
  • 109
    • 84861870244 scopus 로고    scopus 로고
    • Evasion of COPD in smokers: At what price?
    • 10.1183/09031936.00135711 22005915 1:CAS:528:DC%2BC38XhtFSqs7fI
    • Cosio MG, Saetta M. Evasion of COPD in smokers: at what price? Eur Respir J. 2012;39(6):1298-303. doi: 10.1183/09031936.00135711.
    • (2012) Eur Respir J. , vol.39 , Issue.6 , pp. 1298-1303
    • Cosio, M.G.1    Saetta, M.2
  • 110
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • 10.1016/j.cell.2010.02.029 20303877 1:CAS:528:DC%2BC3cXlsVSgu7s%3D
    • Nathan C, Ding A. Nonresolving inflammation. Cell. 2010;140(6):871-82. doi: 10.1016/j.cell.2010.02.029.
    • (2010) Cell. , vol.140 , Issue.6 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 111
    • 84863802574 scopus 로고    scopus 로고
    • Role of CXCL5 in leukocyte recruitment to the lungs during secondhand smoke exposure
    • 10.1165/rcmb.2011-0260OC 22362385 1:CAS:528:DC%2BC38XhtVOrsr3I
    • Balamayooran G, Batra S, Cai S, Mei J, Worthen GS, Penn AL, et al. Role of CXCL5 in leukocyte recruitment to the lungs during secondhand smoke exposure. Am J Respir Cell Mol Biol. 2012;47(1):104-11. doi: 10.1165/rcmb.2011-0260OC.
    • (2012) Am J Respir Cell Mol Biol. , vol.47 , Issue.1 , pp. 104-111
    • Balamayooran, G.1    Batra, S.2    Cai, S.3    Mei, J.4    Worthen, G.S.5    Penn, A.L.6
  • 112
    • 84875466646 scopus 로고    scopus 로고
    • Mechanistic links between COPD and lung cancer
    • 10.1038/nrc3477 23467302 1:CAS:528:DC%2BC3sXjsVKqtb0%3D
    • Houghton AM. Mechanistic links between COPD and lung cancer. Nat Rev Cancer. 2013;13(4):233-45. doi: 10.1038/nrc3477.
    • (2013) Nat Rev Cancer. , vol.13 , Issue.4 , pp. 233-245
    • Houghton, A.M.1
  • 113
    • 79952761958 scopus 로고    scopus 로고
    • Oxidative stress in patients with COPD
    • 21194408 1:CAS:528:DC%2BC3MXktVOktbc%3D
    • Loukides S, Bakakos P, Kostikas K. Oxidative stress in patients with COPD. Curr Drug Targets. 2011;12(4):469-77.
    • (2011) Curr Drug Targets. , vol.12 , Issue.4 , pp. 469-477
    • Loukides, S.1    Bakakos, P.2    Kostikas, K.3
  • 114
    • 0142010546 scopus 로고    scopus 로고
    • Oxidative stress in expired breath condensate of patients with COPD
    • 14555568 1:CAS:528:DC%2BD3sXovF2hs70%3D
    • Kostikas K, Papatheodorou G, Psathakis K, Panagou P, Loukides S. Oxidative stress in expired breath condensate of patients with COPD. Chest. 2003;124(4):1373-80.
    • (2003) Chest. , vol.124 , Issue.4 , pp. 1373-1380
    • Kostikas, K.1    Papatheodorou, G.2    Psathakis, K.3    Panagou, P.4    Loukides, S.5
  • 115
    • 84858785703 scopus 로고    scopus 로고
    • Coordinated regulation of myeloid cells by tumours
    • 10.1038/nri3175 22437938 1:CAS:528:DC%2BC38XksVensrs%3D
    • Gabrilovich DI, Ostrand-Rosenberg S, Bronte V. Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol. 2012;12(4):253-68. doi: 10.1038/nri3175.
    • (2012) Nat Rev Immunol. , vol.12 , Issue.4 , pp. 253-268
    • Gabrilovich, D.I.1    Ostrand-Rosenberg, S.2    Bronte, V.3
  • 116
    • 42349094504 scopus 로고    scopus 로고
    • Tumor escape mechanism governed by myeloid-derived suppressor cells
    • 10.1158/0008-5472.CAN-07-6229 18413722 1:CAS:528:DC%2BD1cXks1Git7s%3D
    • Nagaraj S, Gabrilovich DI. Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res. 2008;68(8):2561-3. doi: 10.1158/0008-5472.CAN-07-6229.
    • (2008) Cancer Res. , vol.68 , Issue.8 , pp. 2561-2563
    • Nagaraj, S.1    Gabrilovich, D.I.2
  • 117
    • 79952280133 scopus 로고    scopus 로고
    • Myeloid cell diversification and complexity: An old concept with new turns in oncology
    • 10.1007/s10555-011-9268-1 21267772
    • Chioda M, Peranzoni E, Desantis G, Papalini F, Falisi E, Solito S, et al. Myeloid cell diversification and complexity: an old concept with new turns in oncology. Cancer Metastasis Rev. 2011;30(1):27-43. doi: 10.1007/s10555-011-9268- 1.
    • (2011) Cancer Metastasis Rev. , vol.30 , Issue.1 , pp. 27-43
    • Chioda, M.1    Peranzoni, E.2    Desantis, G.3    Papalini, F.4    Falisi, E.5    Solito, S.6
  • 118
    • 0035201127 scopus 로고    scopus 로고
    • Tumor-induced immune dysfunctions caused by myeloid suppressor cells
    • 11759067 1:CAS:528:DC%2BD38Xkt1Gi
    • Bronte V, Serafini P, Apolloni E, Zanovello P. Tumor-induced immune dysfunctions caused by myeloid suppressor cells. J Immunother. 2001;24(6):431-46.
    • (2001) J Immunother. , vol.24 , Issue.6 , pp. 431-446
    • Bronte, V.1    Serafini, P.2    Apolloni, E.3    Zanovello, P.4
  • 119
    • 41149119143 scopus 로고    scopus 로고
    • Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
    • 18364001 1:CAS:528:DC%2BD1cXlsFejt74%3D
    • Marigo I, Dolcetti L, Serafini P, Zanovello P, Bronte V. Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol Rev. 2008;222:162-79.
    • (2008) Immunol Rev. , vol.222 , pp. 162-179
    • Marigo, I.1    Dolcetti, L.2    Serafini, P.3    Zanovello, P.4    Bronte, V.5
  • 120
    • 0033564834 scopus 로고    scopus 로고
    • Primary chemically induced tumors induce profound immunosuppression concomitant with apoptosis and alterations in signal transduction in T cells and NK cells
    • 10383160 1:CAS:528:DyaK1MXktVyjsbk%3D
    • Horiguchi S, Petersson M, Nakazawa T, Kanda M, Zea AH, Ochoa AC, et al. Primary chemically induced tumors induce profound immunosuppression concomitant with apoptosis and alterations in signal transduction in T cells and NK cells. Cancer Res. 1999;59(12):2950-6.
    • (1999) Cancer Res. , vol.59 , Issue.12 , pp. 2950-2956
    • Horiguchi, S.1    Petersson, M.2    Nakazawa, T.3    Kanda, M.4    Zea, A.H.5    Ochoa, A.C.6
  • 121
    • 33845997430 scopus 로고    scopus 로고
    • Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion
    • 17178380 1:CAS:528:DC%2BD28XhtlaltL7N
    • Talmadge JE, Hood KC, Zobel LC, Shafer LR, Coles M, Toth B. Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. Int Immunopharmacol. 2007;7(2):140-51.
    • (2007) Int Immunopharmacol. , vol.7 , Issue.2 , pp. 140-151
    • Talmadge, J.E.1    Hood, K.C.2    Zobel, L.C.3    Shafer, L.R.4    Coles, M.5    Toth, B.6
  • 122
    • 0037884830 scopus 로고    scopus 로고
    • Nitric oxide-independent CTL suppression during tumor progression: Association with arginase-producing (M2) myeloid cells
    • 12734351 1:CAS:528:DC%2BD3sXjsVGqsLw%3D
    • Liu Y, Van Ginderachter JA, Brys L, De Baetselier P, Raes G, Geldhof AB. Nitric oxide-independent CTL suppression during tumor progression: association with arginase-producing (M2) myeloid cells. J Immunol. 2003;170(10):5064-74.
    • (2003) J Immunol. , vol.170 , Issue.10 , pp. 5064-5074
    • Liu, Y.1    Van Ginderachter, J.A.2    Brys, L.3    De Baetselier, P.4    Raes, G.5    Geldhof, A.B.6
  • 123
    • 84871127292 scopus 로고    scopus 로고
    • Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth
    • 10.4049/jimmunol.1201018 23152559 1:CAS:528:DC%2BC38Xhsl2jtLnL
    • Schlecker E, Stojanovic A, Eisen C, Quack C, Falk CS, Umansky V, et al. Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth. J Immunol. 2012;189(12):5602-11. doi: 10.4049/jimmunol.1201018.
    • (2012) J Immunol. , vol.189 , Issue.12 , pp. 5602-5611
    • Schlecker, E.1    Stojanovic, A.2    Eisen, C.3    Quack, C.4    Falk, C.S.5    Umansky, V.6
  • 124
    • 84862143053 scopus 로고    scopus 로고
    • Melanoma-induced immunosuppression and its neutralization
    • 10.1016/j.semcancer.2012.02.003 22349515 1:CAS:528:DC%2BC38XosVKjtbg%3D
    • Umansky V, Sevko A. Melanoma-induced immunosuppression and its neutralization. Semin Cancer Biol. 2012;22(4):319-26. doi: 10.1016/j.semcancer. 2012.02.003.
    • (2012) Semin Cancer Biol. , vol.22 , Issue.4 , pp. 319-326
    • Umansky, V.1    Sevko, A.2
  • 125
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • 10.1172/JCI31422 17476345 1:CAS:528:DC%2BD2sXlt1Omtrs%3D
    • Sica A, Bronte V. Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Investig. 2007;117(5):1155-66. doi: 10.1172/JCI31422.
    • (2007) J Clin Investig. , vol.117 , Issue.5 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 126
    • 79953327275 scopus 로고    scopus 로고
    • Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization
    • 10.1002/ijc.26032 21387299 1:CAS:528:DC%2BC3MXktVSgt7o%3D
    • Erez N, Coussens LM. Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization. Int J Cancer. 2011;128(11):2536- 44. doi: 10.1002/ijc.26032.
    • (2011) Int J Cancer , vol.128 , Issue.11 , pp. 2536-2544
    • Erez, N.1    Coussens, L.M.2
  • 127
    • 0347123433 scopus 로고    scopus 로고
    • Tumour-educated macrophages promote tumour progression and metastasis
    • 10.1038/nrc1256 14708027 1:CAS:528:DC%2BD2cXos12qtA%3D%3D
    • Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer. 2004;4(1):71-8. doi: 10.1038/nrc1256.
    • (2004) Nat Rev Cancer , vol.4 , Issue.1 , pp. 71-78
    • Pollard, J.W.1
  • 128
    • 77949345555 scopus 로고    scopus 로고
    • Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
    • 10.1056/NEJMoa0905680 20220182 1:CAS:528:DC%2BC3cXjt1yls7Y%3D
    • Steidl C, Lee T, Shah SP, Farinha P, Han G, Nayar T, et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med. 2010;362(10):875-85. doi: 10.1056/NEJMoa0905680.
    • (2010) N Engl J Med. , vol.362 , Issue.10 , pp. 875-885
    • Steidl, C.1    Lee, T.2    Shah, S.P.3    Farinha, P.4    Han, G.5    Nayar, T.6
  • 129
    • 77549086214 scopus 로고    scopus 로고
    • CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis
    • 10.1016/j.cytogfr.2009.11.009 20005149 1:CAS:528:DC%2BC3cXivFKgsrc%3D
    • Zhang J, Patel L, Pienta KJ. CC chemokine ligand 2 (CCL2) promotes prostate cancer tumorigenesis and metastasis. Cytokine Growth Factor Rev. 2010;21(1):41-8. doi: 10.1016/j.cytogfr.2009.11.009.
    • (2010) Cytokine Growth Factor Rev. , vol.21 , Issue.1 , pp. 41-48
    • Zhang, J.1    Patel, L.2    Pienta, K.J.3
  • 130
    • 0035911221 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
    • 11257139 1:CAS:528:DC%2BD3MXitFKhsLo%3D
    • Lin EY, Nguyen AV, Russell RG, Pollard JW. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med. 2001;193(6):727-40.
    • (2001) J Exp Med. , vol.193 , Issue.6 , pp. 727-740
    • Lin, E.Y.1    Nguyen, A.V.2    Russell, R.G.3    Pollard, J.W.4
  • 131
    • 67651160649 scopus 로고    scopus 로고
    • CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • 10.1016/j.ccr.2009.06.018 19647220 1:CAS:528:DC%2BD1MXhsVCjsrfJ
    • DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell. 2009;16(2):91-102. doi: 10.1016/j.ccr.2009.06.018.
    • (2009) Cancer Cell. , vol.16 , Issue.2 , pp. 91-102
    • Denardo, D.G.1    Barreto, J.B.2    Andreu, P.3    Vasquez, L.4    Tawfik, D.5    Kolhatkar, N.6
  • 133
    • 0034721666 scopus 로고    scopus 로고
    • MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
    • 11081634 1:CAS:528:DC%2BD3cXnvF2ksLg%3D
    • Coussens LM, Tinkle CL, Hanahan D, Werb Z. MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis. Cell. 2000;103(3):481-90.
    • (2000) Cell. , vol.103 , Issue.3 , pp. 481-490
    • Coussens, L.M.1    Tinkle, C.L.2    Hanahan, D.3    Werb, Z.4
  • 134
    • 41649116240 scopus 로고    scopus 로고
    • Plasticity in tumor-promoting inflammation: Impairment of macrophage recruitment evokes a compensatory neutrophil response
    • 18392134 1:CAS:528:DC%2BD1cXltleiurg%3D
    • Pahler JC, Tazzyman S, Erez N, Chen YY, Murdoch C, Nozawa H, et al. Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response. Neoplasia. 2008;10(4):329-40.
    • (2008) Neoplasia. , vol.10 , Issue.4 , pp. 329-340
    • Pahler, J.C.1    Tazzyman, S.2    Erez, N.3    Chen, Y.Y.4    Murdoch, C.5    Nozawa, H.6
  • 135
    • 77349109251 scopus 로고    scopus 로고
    • Mast cell tryptase promotes breast cancer migration and invasion
    • 20126998 1:CAS:528:DC%2BC3cXjtlGrsbs%3D
    • Xiang M, Gu Y, Zhao F, Lu H, Chen S, Yin L. Mast cell tryptase promotes breast cancer migration and invasion. Oncol Rep. 2010;23(3):615-9.
    • (2010) Oncol Rep. , vol.23 , Issue.3 , pp. 615-619
    • Xiang, M.1    Gu, Y.2    Zhao, F.3    Lu, H.4    Chen, S.5    Yin, L.6
  • 136
    • 76249110097 scopus 로고    scopus 로고
    • Interleukin-6 increases expression and secretion of cathepsin B by breast tumor-associated monocytes
    • 10.1159/000276564 20110692 1:CAS:528:DC%2BC3cXht1Slsrk%3D
    • Mohamed MM, Cavallo-Medved D, Rudy D, Anbalagan A, Moin K, Sloane BF. Interleukin-6 increases expression and secretion of cathepsin B by breast tumor-associated monocytes. Cell Physiol Biochem. 2010;25(2-3):315-24. doi: 10.1159/000276564.
    • (2010) Cell Physiol Biochem. , vol.25 , Issue.2-3 , pp. 315-324
    • Mohamed, M.M.1    Cavallo-Medved, D.2    Rudy, D.3    Anbalagan, A.4    Moin, K.5    Sloane, B.F.6
  • 137
    • 77953914366 scopus 로고    scopus 로고
    • Tumor-induced tolerance and immune suppression depend on the C/EBPβ transcription factor
    • 10.1016/j.immuni.2010.05.010 20605485 1:CAS:528:DC%2BC3cXovVahtbc%3D
    • Marigo I, Bosio E, Solito S, Mesa C, Fernandez A, Dolcetti L, et al. Tumor-induced tolerance and immune suppression depend on the C/EBPβ transcription factor. Immunity. 2010;32(6):790-802. doi: 10.1016/j.immuni.2010. 05.010.
    • (2010) Immunity , vol.32 , Issue.6 , pp. 790-802
    • Marigo, I.1    Bosio, E.2    Solito, S.3    Mesa, C.4    Fernandez, A.5    Dolcetti, L.6
  • 138
    • 77955384579 scopus 로고    scopus 로고
    • Gr-1+ CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung
    • 10.1158/0008-5472.CAN-10-0706 20631080 1:CAS:528:DC%2BC3cXpsVCntLo%3D
    • Yan HH, Pickup M, Pang Y, Gorska AE, Li Z, Chytil A, et al. Gr-1+ CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res. 2010;70(15):6139-49. doi: 10.1158/0008-5472.CAN- 10-0706.
    • (2010) Cancer Res. , vol.70 , Issue.15 , pp. 6139-6149
    • Yan, H.H.1    Pickup, M.2    Pang, Y.3    Gorska, A.E.4    Li, Z.5    Chytil, A.6
  • 139
    • 79960411324 scopus 로고    scopus 로고
    • CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
    • 10.1038/nature10138 21654748 1:CAS:528:DC%2BC3MXntFKrsb0%3D
    • Qian BZ, Li J, Zhang H, Kitamura T, Zhang J, Campion LR, et al. CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis. Nature. 2011;475(7355):222-5. doi: 10.1038/nature10138.
    • (2011) Nature. , vol.475 , Issue.7355 , pp. 222-225
    • Qian, B.Z.1    Li, J.2    Zhang, H.3    Kitamura, T.4    Zhang, J.5    Campion, L.R.6
  • 140
    • 68749109536 scopus 로고    scopus 로고
    • A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth
    • 10.1371/journal.pone.0006562 19668347
    • Qian B, Deng Y, Im JH, Muschel RJ, Zou Y, Li J, et al. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS ONE. 2009;4(8):e6562. doi: 10.1371/journal.pone. 0006562.
    • (2009) PLoS ONE. , vol.4 , Issue.8 , pp. 6562
    • Qian, B.1    Deng, Y.2    Im, J.H.3    Muschel, R.J.4    Zou, Y.5    Li, J.6
  • 141
    • 77955410185 scopus 로고    scopus 로고
    • Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1β-dependent stabilization of Snail in tumor cells
    • 10.1371/journal.pone.0011700 20661477
    • Kaler P, Galea V, Augenlicht L, Klampfer L. Tumor associated macrophages protect colon cancer cells from TRAIL-induced apoptosis through IL-1β-dependent stabilization of Snail in tumor cells. PLoS ONE. 2010;5(7):e11700. doi: 10.1371/journal.pone.0011700.
    • (2010) PLoS ONE. , vol.5 , Issue.7 , pp. 11700
    • Kaler, P.1    Galea, V.2    Augenlicht, L.3    Klampfer, L.4
  • 142
    • 0030979282 scopus 로고    scopus 로고
    • Increased recurrence and metastasis in patients whose primary head and neck squamous cell carcinomas secreted granulocyte-macrophage colony-stimulating factor and contained CD34+ natural suppressor cells
    • 9036872 1:STN:280:DyaK2s7ovVartQ%3D%3D
    • Young MR, Wright MA, Lozano Y, Prechel MM, Benefield J, Leonetti JP, et al. Increased recurrence and metastasis in patients whose primary head and neck squamous cell carcinomas secreted granulocyte-macrophage colony-stimulating factor and contained CD34+ natural suppressor cells. Int J Cancer. 1997;74(1):69-74.
    • (1997) Int J Cancer. , vol.74 , Issue.1 , pp. 69-74
    • Young, M.R.1    Wright, M.A.2    Lozano, Y.3    Prechel, M.M.4    Benefield, J.5    Leonetti, J.P.6
  • 143
    • 80052178466 scopus 로고    scopus 로고
    • A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells
    • 10.1182/blood-2010-12-325753 21734236 1:CAS:528:DC%2BC3MXhtFGisrfN
    • Solito S, Falisi E, Diaz-Montero CM, Doni A, Pinton L, Rosato A, et al. A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. Blood. 2011;118(8):2254-65. doi: 10.1182/blood-2010-12-325753.
    • (2011) Blood. , vol.118 , Issue.8 , pp. 2254-2265
    • Solito, S.1    Falisi, E.2    Diaz-Montero, C.M.3    Doni, A.4    Pinton, L.5    Rosato, A.6
  • 144
    • 54849440346 scopus 로고    scopus 로고
    • Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
    • 10.1007/s00262-008-0523-4 18446337 1:CAS:528:DC%2BD1cXht1yqs7bN
    • Diaz-Montero CM, Salem ML, Nishimura MI, Garrett-Mayer E, Cole DJ, Montero AJ. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin- cyclophosphamide chemotherapy. Cancer Immunol Immunother. 2009;58(1):49-59. doi: 10.1007/s00262-008-0523-4.
    • (2009) Cancer Immunol Immunother. , vol.58 , Issue.1 , pp. 49-59
    • Diaz-Montero, C.M.1    Salem, M.L.2    Nishimura, M.I.3    Garrett-Mayer, E.4    Cole, D.J.5    Montero, A.J.6
  • 145
    • 20244367914 scopus 로고    scopus 로고
    • Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: A mechanism of tumor evasion
    • 10.1158/0008-5472.CAN-04-4505 15833831 1:CAS:528:DC%2BD2MXjt1yks7g%3D
    • Zea AH, Rodriguez PC, Atkins MB, Hernandez C, Signoretti S, Zabaleta J, et al. Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res. 2005;65(8):3044-8. doi: 10.1158/0008-5472.CAN-04-4505.
    • (2005) Cancer Res. , vol.65 , Issue.8 , pp. 3044-3048
    • Zea, A.H.1    Rodriguez, P.C.2    Atkins, M.B.3    Hernandez, C.4    Signoretti, S.5    Zabaleta, J.6
  • 146
    • 70349240416 scopus 로고    scopus 로고
    • Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor
    • 10.1002/hep.23054 19551844 1:CAS:528:DC%2BD1MXhtFKntL%2FI
    • Hoechst B, Voigtlaender T, Ormandy L, Gamrekelashvili J, Zhao F, Wedemeyer H, et al. Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor. Hepatology. 2009;50(3):799-807. doi: 10.1002/hep.23054.
    • (2009) Hepatology. , vol.50 , Issue.3 , pp. 799-807
    • Hoechst, B.1    Voigtlaender, T.2    Ormandy, L.3    Gamrekelashvili, J.4    Zhao, F.5    Wedemeyer, H.6
  • 147
    • 84864662070 scopus 로고    scopus 로고
    • Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival
    • doi: 10.1038/nm.2883
    • Walter S, Weinschenk T, Stenzl A, Zdrojowy R, Pluzanska A, Szczylik C, et al. Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med. 2012. doi: 10.1038/nm.2883.
    • (2012) Nat Med.
    • Walter, S.1    Weinschenk, T.2    Stenzl, A.3    Zdrojowy, R.4    Pluzanska, A.5    Szczylik, C.6
  • 148
    • 84866920497 scopus 로고    scopus 로고
    • Immune tolerance to tumor antigens occurs in a specialized environment of the spleen
    • 10.1016/j.celrep.2012.08.006 22959433 1:CAS:528:DC%2BC38XhsFSmsL3O
    • Ugel S, Peranzoni E, Desantis G, Chioda M, Walter S, Weinschenk T, et al. Immune tolerance to tumor antigens occurs in a specialized environment of the spleen. Cell Reports. 2012;2(3):628-39. doi: 10.1016/j.celrep.2012.08.006.
    • (2012) Cell Reports. , vol.2 , Issue.3 , pp. 628-639
    • Ugel, S.1    Peranzoni, E.2    Desantis, G.3    Chioda, M.4    Walter, S.5    Weinschenk, T.6
  • 149
    • 78649586268 scopus 로고    scopus 로고
    • The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity
    • 10.1002/eji.201040895 21061430 1:CAS:528:DC%2BC3cXhtl2isbfK
    • Youn JI, Gabrilovich DI the biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur J Immunol. 2010;40(11):2969-75. doi: 10.1002/eji.201040895.
    • (2010) Eur J Immunol. , vol.40 , Issue.11 , pp. 2969-2975
    • Youn, J.I.1    Gabrilovich, D.I.2
  • 150
    • 84255170451 scopus 로고    scopus 로고
    • Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells
    • 10.1158/0008-5472.CAN-11-1766 21987727 1:CAS:528:DC%2BC3MXhs1agtr3F
    • Daftarian P, Kaifer AE, Li W, Blomberg BB, Frasca D, Roth F, et al. Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells. Cancer Res. 2011;71(24):7452-62. doi: 10.1158/0008-5472.CAN-11-1766.
    • (2011) Cancer Res. , vol.71 , Issue.24 , pp. 7452-7462
    • Daftarian, P.1    Kaifer, A.E.2    Li, W.3    Blomberg, B.B.4    Frasca, D.5    Roth, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.