Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development

American Journal of Clinical Nutrition

Volumn 76, Issue 1, 2002, Pages 128-140

  De Jonge, Wouter J ^a   Hallemeesch, Marcello M ^b   Kwikkers, Karin L ^a   Ruijter, Jan M ^a   De Vries, Carrie Gier De ^a   Van Roon, Marian A ^a   Meijer, Alfred J ^a   Marescau, Bart ^a,c   De Deyn, Peter P ^c   Deutz, Nicolaas E P ^b   Lamers, Wouter H ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Arginase I; Arginine; Enterocytes; Hair; Immunonutrition; Myocyte; Peyer's patch; Transgenic mice

Indexed keywords

AMINO ACID; AMMONIA; ARGINASE; ARGININE; CREATINE; DNA; HYALIN; IMMUNOGLOBULIN; NITRIC OXIDE SYNTHASE; TRANSFER RNA;

AMINO ACID DEFICIENCY; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENT; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HAIR GROWTH; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMEOSTASIS; IMMUNOBLOTTING; IN SITU HYBRIDIZATION; INTESTINE CELL; LYMPHOID CELL; MALE; MOUSE; MUSCLE; MUSCLE GROWTH; NONHUMAN; PEYER PATCH; PHENOTYPE; PROTEIN EXPRESSION; SKIN; SOUTHERN BLOTTING; TRANSGENIC MOUSE;

ANIMALIA; MAMMALIA; MURINAE; MUS MUSCULUS;

EID: 0036291267     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/76.1.128     Document Type: Article

References (57)

1. Relative importance of kidney and liver in synthesis of arginine by the rat
2. Renal arginine synthesis: Studies in vitro and in vivo
3. Glutamine utilization by the small intestine
4. Uptake and metabolism of plasma glutamine by the small intestine
5. Arginine synthesis in enterocytes of neonatal pigs
6. Arginine metabolism: Nitric oxide and beyond
7. Arginine needs, physiological state and usual diets. A reevaluation
8. Amino acid compositions of body and milk protein change during the suckling period in rats
9. Free and protein-bound amino acids in sow's colostrum and milk
10. Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs
11. Arginine synthesis in enterocytes of neonatal pigs
12. Arginine-metabolizing enzymes in the developing rat small intestine
13. Plasma L-arginine concentrations in premature infants with necrotizing enterocolitis
14. Arginine-responsive asymptomatic hyperammonemia in the premature infant
15. Sparse-fur (spf) mouse as a model of hyperammonemia: Alterations in the neurotransmitter systems
16. Inhibition of intestinal citrulline synthesis causes severe growth retardation in rats
17. Dietary arginine and the prevention of cardiovascular diseases
18. Is atherosclerosis an arginine deficiency disease?
19. Arginine and immune function
20. Arginine enhances induction of T helper 1 and T helper 2 cytokine synthesis by Peyer's patch alpha beta T cells and antigen-specific mucosal immune response
21. The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships
22. Structural organization of the gene for rat liver-type arginase
23. The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands
24. Complete nucleotide sequence of cDNA and deduced amino acid sequence of rat liver arginase
25. Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2-3 microns Spherisorb ODS II column
26. Comparative study of guanidino compounds in serum and brain of mouse, rat, rabbit, and man
27. Ultramicrodetermination of plasma urea by reaction with diacetylmonoxime-antipyrine without deproteinization
28. Radio-isotopic in situ hybridization on tissue sections. Practical aspects and quantification
29. Presence of argininosuccinate synthetase in glial cells as revealed by peptide-specific antisera
30. Immunocytochemical localization of argininosuccinate synthetase in the rat brain
31. Gene expression in derivatives of embryonic foregut during prenatal development of the rat
32. Radioimmunochemical determination of carbamoyl-phosphate synthase (ammonia) content of adult rat liver
33. Differential effects of thyroxine and cortisone on jejunal sucrase expression in suckling rats
34. Cloning and characterization of the mouse and rat type II arginase genes
35. The unlabeled antibody enzyme method of immunohistochemistry: Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes
36. The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein
37. Ornithine transcarbamylase deficiency in mutant mice I. Studies on the characterization of enzyme defect and suitability as animal model of human disease
38. Properties of immunoglobulin G-Fc receptors from neonatal rat intestinal brush borders
39. Guanidino compound analysis as a complementary diagnostic parameter for hyperargininemia: Follow-up of guanidino compound levels during therapy
40. Reduced arginine plasma levels are the drive for arginine production by the kidney in the rat
41. Convergence of apical and basolateral endocytic pathways at apical late endosomes in absorptive cells of suckling rat ileum in vivo
42. Three distinctive steps in Peyer's patch formation of murine embryo
43. Targeted disruption of the neuronal nitric oxide synthase gene
44. Mice lacking inducible nitric oxide synthase are not resistant to lipopolysaccharide-induced death
45. Elevated blood pressures in mice lacking endothelial nitric oxide synthase
46. Free amino acid levels in serum and small intestine during the post-natal development of normal and sparse-fur mutant mice
47. Arginine-related guanidino compounds and nitric oxide synthase in the brain of ornithine transcarbamylase deficient spf mutant mouse: Effect of metabolic arginine deficiency
48. The transmission of - 125-I-labelled immunoglobulin G by proximal and distal regions of the small intestine of 16-day-old rats
49. Comparison of the complexed and free forms of rat liver arginyl-tRNA synthetase and origin of the free form
50. The maximum rate of gene expression is dependent on the downstream context of unfavourable codons
51. Creatine deficiency in the brain: A new, treatable inborn error of metabolism
52. Absence of integrin alpha 7 causes a novel form of muscular dystrophy
53. Arginine stimulates lymphocyte immune response in healthy human beings
54. Nitric oxide in autoimmune disease: Cytotoxic or regulatory mediator?
55. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor
56. Defective Peyer's patch organogenesis in mice lacking the 55-kD receptor for tumor necrosis factor
57. Organogenic role of B lymphocytes in mucosal immunity