Inflammatory cells of immunosuppressive phenotypes in oral lichen planus have a proinflammatory pattern of expression and are associated with clinical parameters

Clinical Oral Investigations

Volumn 17, Issue 5, 2013, Pages 1365-1373

  Vered, Marilena ^a,b   Fürth, Eran ^c   Shalev, Yifat ^a   Dayan, Dan ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Immune suppressive protumorigenic cells; Myeloid derived suppressive cells; Novel treatment approach; Oral lichen planus; Regulatory T cells; Tumor associated macrophages

Indexed keywords

EID: 84878285077     PISSN: 14326981     EISSN: 14363771     Source Type: Journal    
DOI: 10.1007/s00784-012-0814-1     Document Type: Article

References (42)

1. Roopashree MR, Gondhalekar RV, Shashikanth MC, George J, Thippeswamy SH, Shukla A (2010) Pathogenesis of oral lichen planus-a review. J Oral Pathol Med 39: 729-734.
2. Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K (2005) Current controversies in oral lichen planus: report of an international consensus meeting. Part 1. Viral infections and etiopathogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100: 40-51.
3. Zhang J, Zhou G, Du GF, Xu XY, Zhou HM (2011) Biologics, an alternative therapeutic approach for oral lichen planus. J Oral Pathol Med 40: 521-524.
4. Crincoli V, Di Bisceglie MB, Scivetti M, Lucchese A, Tecco S, Festa F (2011) Oral lichen planus: update on etiopathogenesis, diagnosis and treatment. Immunopharmacol Immunotoxicol 33: 11-20.
5. El Naggar AK, Reichart PA (2005) Proliferative verrucous leukoplakia and precancerous condition. In: Barnes L, Eveson JW, Reichart P, Sidransky D (eds) World Organization Classification of tumours. Pathology and genetics. Head and neck tumours. IARC, Lyon, pp 180-181.
6. Tao XA, Xia J, Chen XB, Wang H, Dai YH, Rhodus NL et al (2010) FOXP3 T regulatory cells in lesions of oral lichen planus correlated with disease activity. Oral Dis 16: 76-82.
7. Sica A, Bronte V (2007) Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 117: 1155-1166.
8. Wang HY, Wang RF (2007) Regulatory T cells and cancer. Curr Opin Immunol 19: 217-223.
9. Lee YK, Mukasa R, Hatton RD, Weaver CT (2009) Developmental plasticity of Th17 and Treg cells. Curr Opin Immunol 21: 274-280.
10. Sato M, Tokuda N, Fukumoto T, Mano T, Sato T, Ueyama Y (2006) Immunohistopathological study of the oral lichenoid lesions of chronic GVHD. J Oral Pathol Med 35: 33-36.
11. Karin M, Greten FR (2005) NF-kappa B: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol 5: 749-759.
12. Phipps KD, Surette AP, O'Connell PA, Waisman DM (2011) Plasminogen receptor S100A10 is essential for the migration of tumor-promoting macrophages into tumor sites. Cancer Res 71: 6676-6683.
13. Hallam S, Escorcio-Correia M, Soper R, Schultheiss A, Hagemann T (2009) Activated macrophages in the tumour microenvironment-dancing to the tune of TLR and NF-kappaB. J Pathol 219: 143-152.
14. Mantovani A, Allavena P, Sica A, Balkwill F (2008) Cancer-related inflammation. Nature 454: 436-444.
15. Lin WW, Karin M (2007) A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117: 1175-1183.
16. Allavena P, Germano G, Marchesi F, Mantovani A (2011) Chemokines in cancer related inflammation. Exp Cell Res 317: 664-673.
17. Sethi G, Sung B, Aggarwal BB (2008) Nuclear factor-kappaB activation: from bench to bedside. Exp Biol Med (Maywood) 233: 21-31.
18. Gannot G, Gannot I, Vered H, Buchner A, Keisari Y (2006) Increase in immune cell infiltration with progression of oral epithelium from hyperkeratosis to dysplasia and carcinoma. Br J Cancer 86: 1444-1448.
19. Hirshberg A, Amariglio N, Akrish S, Yahalom R, Rosenbaum H, Okon E et al (2006) Traumatic ulcerative granuloma with stromal eosinophilia-a reactive lesion of the oral mucosa. Am J Clin Pathol 126: 522-529.
20. Rogers HW, Sheehan KC, Brunt LM, Dower SK, Unanue ER, Schreiber RD (1992) Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice. Proc Natl Acad Sci USA 89: 1011-1015.
21. Massimo H, Ohguro N, Nomura S, Hashida N, Nakai K, Tano Y (2008) Neutrophil chemotaxis and local expression of interleukin-10 in the tolerance of endotoxin-induced uveitis. Invest Ophthalmol Vis Sci 49: 5450-5457.
22. Matsumoto Y, Horiike S, Ohshiro M, Yamamoto M, Sasaki N, Tsutsumi T et al (2010) Expression of master regulators of helper T-cell differentiation in peripheral T-cell lymphoma, not otherwise specified, by immunohistochemical analysis. Am J Clin Pathol 133: 281-290.
23. Lamb RJ, Capocasale RJ, Duffy KE, Sarisky RT, Mbow ML (2007) Identification and characterization of novel bone marrow myeloid DEC205+ Gr-1+ cell subsets that differentially express chemokine and TLRs. J Immunol 178: 7833-7839.
24. Quaranta MG, Mattioli B, Spadaro F, Straface E, Giordani L, Ramoni C et al (2003) HIV-1 Nef triggers Vav-mediated signaling pathway leading to functional and morphological differentiation of dendritic cells. FASEB 17: 2025-2036.
25. Theilig F, Enke AK, Scolari B, Polzin D, Bachmann S, Koesters R (2011) TGF-β tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis. Am J Pathol 179: 2177-2188.
26. Kastelan M, Prpić Massari L, Gruber F, Zamolo G, Zauhar G, Coklo M et al (2004) The role of perforin-mediated apoptosis in lichen planus lesions. Arch Dermatol Res 296: 226-230.
27. Mignogna MD, Fedele S, Lo Russo L, Lo Muzio L, Bucci E (2004) Immune activation and chronic inflammation as the cause of malignancy in oral lichen planus: is there any evidence? Oral Oncol 40: 120-130.
28. Timmermann M, Buck F, Sorg C, Hogger P (2004) Interaction of soluble CD163 with activated T lymphocytes involves its association with non-muscle myosin heavy chain type A. Immunol Cell Biol 82: 479-487.
29. Ben-Neriah Y, Karin M (2011) Inflammation meets cancer, with NF-κB as the matchmaker. Nat Immunol 12: 715-723.
30. Fuentes-Duculan J, Suárez-Fariñas M, Zaba LC, Nograles KE, Pierson KC, Mitsui H et al (2010) A subpopulation of CD163-positive macrophages is classically activated in psoriasis. J Invest Dermatol 130: 2412-2422.
31. Yamazaki T, Akiba H, Koyanagi A, Azuma M, Yagita H, Okumura K (2005) Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production. J Immunol 175: 1586-1592.
32. Long M, Park SG, Strickland I, Hayden MS, Ghosh S (2009) Nuclear factor-κB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity 31: 921-931.
33. Torihata H, Ishikawa F, Okada Y, Tanaka Y, Uchida T, Suguro T et al (2004) Irradiation up-regulates CD80 expression through two different mechanisms in spleen B cells, B lymphoma cells, and dendritic cells. Immunology 112: 219-227.
34. Yang R, Cai Z, Zhang Y, Yutzy WH, Roby KF, Roden RB (2006) CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells. Cancer Res 66: 6807-6815.
35. Valmori D, Raffin C, Raimbaud I, Ayyoub M (2010) Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+Treg in the presence of lineage-specific polarizing factors. Proc Natl Acad Sci USA 107: 19402-19407.
36. Liu G, Ma H, Qiu L, Li L, Cao Y, Ma J et al (2011) Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice. Immunol Cell Biol 89: 130-142.
37. Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K (2005) Current controversies in oral lichen planus: report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100: 164-178.
38. Keenan AV, Ferraiolo D (2011) Insufficient evidence for effectiveness of any treatment for oral lichen planus. Evid Based Dent 12: 85-86.
39. Sugerman PB, Savage NW, Walsh LJ, Zhao ZZ, Zhou XJ, Khan A et al (2002) The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med 13: 350-365.
40. Mani H, Sidhu GS, Kumari R, Gaddipatil JP, Seth P, Maheshwari RK (2002) Curcumin differentially regulates TGF-β1, its receptors and nitric oxide synthase during impaired wound healing. Biofactors 16: 29-43.
41. Fu S, Kurzrock R (2010) Development of curcumin as an epigenetic agent. Cancer 116: 4670-4676.
42. Chainani-Wu N, Madden E, Lozada-Nur F, Silverman S (2011) High-dose curcuminoids are efficacious in the reduction in symptoms and signs of oral lichen planus. J Am Acad Dermatol. doi: 10. 1016/j. jaad. 2011. 04. 022.