Mast cell tryptase promotes breast cancer migration and invasion

Oncology Reports

Volumn 23, Issue 3, 2010, Pages 615-619

  Xiang, Meng ^a   Gu, Yiping ^a   Zhao, Fengdi ^a   Lu, Hong ^a   Chen, Sifeng ^a   Yin, Lianhua ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Breast cancer; Mast cell; Matrix metalloproteinase 2; Metastasis; Tryptase

Indexed keywords

GELATINASE A; TRYPTASE;

ADULT; ARTICLE; BREAST CANCER; CANCER CELL; CANCER GRADING; CANCER INVASION; CELL MIGRATION; CELL PROLIFERATION; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MORPHOMETRICS; PRIORITY JOURNAL; PROTEIN FUNCTION;

ADULT; AGED; BREAST NEOPLASMS; CELL MOVEMENT; CELL PROLIFERATION; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; MIDDLE AGED; NEOPLASM INVASIVENESS; TRYPTASES;

EID: 77349109251     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or_00000676     Document Type: Article

References (19)

1. Irani AM, Bradford TR, Kepley CL, Schechter NM and Schwartz LB: Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies. J Histochem Cytochem 37: 1509-1515, 1989.
2. Toth-Jakatics R, Jimi S, Takebayashi S and Kawamoto N: Cutaneous malignant melanoma: correlation between neovascularization and peritumor accumulation of mast cells overexpressing vascular endothelial growth factor. Hum Pathol 31: 955-960, 2000.
3. Kankkunen JP, Harvima IT and Naukkarinen A: Quantitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions. Int J Cancer 72: 385-388, 1997.
4. Iamaroon A, Pongsiriwet S, Jittidecharaks S, Pattanaporn K, Prapayasatok S and Wanachantararak S: Increase of mast cells and tumor angiogenesis in oral squamous cell carcinoma. J Oral Pathol Med 32: 195-199, 2003.
5. Wedemeyer J and Galli SJ: Decreased susceptibility of mast cell-deficient Kit(W)/Kit(W-v) mice to the development of 1, 2-dimethylhydrazine-induced intestinal tumors. Lab Invest 85: 388-396, 2005.
6. Schwartz LB: Tryptase: a mast cell serine protease. Methods Enzymol 244: 88-100, 1994.
7. Schwartz LB, Bradford TR, Rouse C, Irani AM, Rasp G, Van der Zwan JK and Van der Linden PW: Development of a new, more sensitive immunoassay for human tryptase: use in systemic anaphylaxis. J Clin Immunol 14: 190-204, 1994.
8. Nagano T, Hao JL, Nakamura M, Kumagai N, Abe M, Nakazawa T and Nishida T: Stimulatory effect of pseudomonal elastase on collagen degradation by cultured keratocytes. Invest Ophthalmol Vis Sci 42: 1247-1253, 2001.
9. Lebeau A, Muller-Aufdemkamp C, Allmacher C, Sauer U, Nerlich A, Lichtinghagen R and Lohrs U: Cellular protein and mRNA expression patterns of matrix metalloproteinases-2, -3 and -9 in human breast cancer: correlation with tumour growth. J Mol Histol 35: 443-455, 2004.
10. Samoszuk M and Corwin MA: Mast cell inhibitor cromolyn increases blood clotting and hypoxia in murine breast cancer. Int J Cancer 107: 159-163, 2003.
11. Ren S, Lawson AE, Carr M, Baumgarten CM and Schwartz LB: Human tryptase fibrinogenolysis is optimal at acidic pH and generates anticoagulant fragments in the presence of the antitryptase monoclonal antibody B12. J Immunol 159: 3540-3548, 1997.
12. Binley K, Askham Z, Martin L, Spearman H, Day D, Kingsman S and Naylor S: Hypoxia-mediated tumour targeting. Gene Ther 10: 540-549, 2003.
13. Steiner DR, Gonzalez NC and Wood JG: Mast cells mediate the microvascular inflammatory response to systemic hypoxia. J Appl Physiol 94: 325-334, 2003.
14. Yoon SO, Park SJ, Yun CH and Chung AS: Roles of matrix metalloproteinases in tumor metastasis and angiogenesis. J Biochem Mol Biol 36: 128-137, 2003.
15. Westermarck J and Kahari VM: Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 13: 781-792, 1999.
16. Curran S and Murray GI: Matrix metalloproteinases in tumour invasion and metastasis. J Pathol 189: 300-308, 1999.
17. Kurizaki T, Toi M and Tominaga T: Relationship between matrix metalloproteinase expression and tumor angiogenesis in human breast carcinoma. Oncol Rep 5: 673-677, 1998.
18. Papathoma AS, Petraki C, Grigorakis A, Papakonstantinou H, Karavana V, Stefanakis S, Sotsiou F and Pintzas A: Prognostic significance of matrix metalloproteinases 2 and 9 in bladder cancer. Anticancer Res 20: 2009-2013, 2000.
19. Yamamoto K, Kumagai N, Fukuda K, Fujitsu Y and Nishida T: Activation of corneal fibroblast-derived matrix metalloproteinase-2 by tryptase. Curr Eye Res 31: 313-317, 2006.