Post-translational and post-transcriptional modifications of pregnane X receptor (PXR) in regulation of the cytochrome P450 superfamily

Current Drug Metabolism

Volumn 14, Issue 10, 2013, Pages 1059-1069

  Smutny, Tomas ^a   Mani, Sridhar ^b   Pavek, Petr ^a  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cytochrome P450; Gene regulation; Induction; Post transcriptional; Post translational modification; Pregnane X receptor; PXR

Indexed keywords

CYTOCHROME P450; PREGNANE X RECEPTOR; RETINOID X RECEPTOR;

ACETYLATION; ARTICLE; CELL PROLIFERATION; DNA BINDING; DNA MODIFICATION; GENE CONTROL; GENETIC ASSOCIATION; HORMONE ACTION; HUMAN; INFLAMMATION; LIGAND BINDING; LIVER; NONHUMAN; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; REGULATORY DNA SEQUENCE; RNA PROCESSING; SIGNAL TRANSDUCTION; SUMOYLATION; TRANSACTIVATION; UBIQUITINATION; XENOBIOTIC METABOLISM;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; HUMANS; LIVER; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, STEROID; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; XENOBIOTICS;

EID: 84891335012     PISSN: 13892002     EISSN: 18755453     Source Type: Journal    
DOI: 10.2174/1389200214666131211153307     Document Type: Article

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