The role of hepatocyte RXRα in xenobiotic-sensing nuclear receptor-mediated pathways

European Journal of Pharmaceutical Sciences

Volumn 15, Issue 1, 2002, Pages 89-96

  Cai, Yan ^a   Konishi, Tamiko ^a   Han, Guang ^a   Campwala, Khozema H ^a   French, Samuel W ^a   Wan, Yu Jui Yvonne ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Constitutive androstane receptor; CYP450; Nulcear receptor; Peroxisome proliferator activated receptor; Pregnane X receptor; Retinoid x receptor; Xenobiotic

Indexed keywords

BIOSENSORS; GENES;

NUCLEAR RECEPTORS;

DRUG PRODUCTS;

1,4 BIS(3,5 DICHLORO 2 PYRIDYLOXY)BENZENE; 16ALPHA CYANOPREGNENOLONE; ANDROSTANE DERIVATIVE; CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; CYTOCHROME P450 2A5; CYTOCHROME P450 2B10; CYTOCHROME P450 2D6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A1; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIRINIXIC ACID; PREGNANE X RECEPTOR; RECEPTOR; RETINOID X RECEPTOR; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; HEPATOMEGALY; IN VIVO STUDY; LIVER CELL; MALE; MORPHOLOGICAL TRAIT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROVOCATION TEST; REGULATORY MECHANISM; XENOBIOTIC METABOLISM;

ANDROSTANOLS; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION; HEPATOCYTES; HEPATOMEGALY; MALE; MICE; MICE, KNOCKOUT; PYRIDINES; PYRIMIDINES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEROID HYDROXYLASES; TRANSCRIPTION FACTORS; XENOBIOTICS;

EID: 0036170810     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00211-1     Document Type: Article

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