RHOA Is a Modulator of the Cholesterol-Lowering Effects of Statin

PLoS Genetics

Volumn 8, Issue 11, 2012, Pages

  Medina, Marisa W ^a   Theusch, Elizabeth ^a   Naidoo, Devesh ^a   Bauzon, Frederick ^a   Stevens, Kristen ^a   Mangravite, Lara M ^b   Kuang, Yu Lin ^a   Krauss, Ronald M ^a  

^a CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^b SAGE BIONETWORKS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL ESTER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PRAVASTATIN; SIMVASTATIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTOME;

ALLELE; ARTICLE; CELL IMMORTALIZATION; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL METABOLISM; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; DRUG RESPONSE; GENE; GENE EXPRESSION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC IDENTIFICATION; GENETIC MARKER; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HEPATOMA CELL; HMG COA REDUCTASE GENE; HOMEOSTASIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOBLASTOID CELL; PHARMACOGENETICS; PLEIOTROPY; RAS HOMOLOG GENE FAMILY MEMBER A; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM;

ALLELES; BIOMARKERS, PHARMACOLOGICAL; CELL LINE, TRANSFORMED; CHOLESTEROL; CLINICAL TRIALS AS TOPIC; GENE EXPRESSION; HUMANS; LIPID METABOLISM; POLYMORPHISM, SINGLE NUCLEOTIDE; PRAVASTATIN; RHOA GTP-BINDING PROTEIN; RNA, MESSENGER; SIMVASTATIN;

EID: 84870674799     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003058     Document Type: Article

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