Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 52, 2012, Pages 21307-21312

  Craciun, Smaranda ^a   Balskus, Emily P ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

Choline trimethylamine lyase; Fragmentation; Gastrointestinal tract; Metabolism; Trimethylaminuria

Indexed keywords

CARBON; CHOLINE; ENZYME; NITROGEN; TRIMETHYLAMINE;

ARTICLE; BACTERIAL GENOME; BIOINFORMATICS; ELECTRON SPIN RESONANCE; ENZYME MECHANISM; ESCHERICHIA COLI; GENE CLUSTER; GENOME; MICROFLORA; NONHUMAN; PRIORITY JOURNAL;

ANAEROBIOSIS; CHOLINE; COMPUTATIONAL BIOLOGY; DESULFOVIBRIO DESULFURICANS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; GENES, BACTERIAL; GENETIC ASSOCIATION STUDIES; GLYCINE; HUMANS; LYASES; METHYLAMINES; MULTIGENE FAMILY; MUTATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 84871837954     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1215689109     Document Type: Article

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