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Volumn 33, Issue 6, 2013, Pages 1427-1434

A systems biology framework identifies molecular underpinnings of coronary heart disease

(23)  Huan, Tianxiao a,b   Zhang, Bin c,d,f   Wang, Zhi e,g   Joehanes, Roby a,b,h   Zhu, Jun c,d,f   Johnson, Andrew D a,b   Ying, Saixia h   Munson, Peter J h   Raghavachari, Nalini b   Wang, Richard b   Liu, Poching b   Courchesne, Paul a   Hwang, Shih Jen a   Assimes, Themistocles L i   McPherson, Ruth j   Samani, Nilesh J k   Schunkert, Heribert c   Meng, Qingying l   Suver, Christine e   O'Donnell, Christopher J b   more..


Author keywords

Coexpression network; Coronary heart disease; Gene expression; Systems biology

Indexed keywords

AGED; ARTICLE; B LYMPHOCYTE ACTIVATION; CONTROLLED STUDY; FEMALE; GENE; GENE CONSTRUCT; GENE CONTROL; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; IMMUNE RESPONSE; ION TRANSPORT; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMS BIOLOGY;

EID: 84879121298     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300112     Document Type: Article
Times cited : (143)

References (39)
  • 1
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the global burden of disease study 2010
    • Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2095-2128.
    • (2012) Lancet. , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3
  • 2
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis. The road ahead
    • Glass CK, Witztum JL. Atherosclerosis. the road ahead. Cell. 2001;104:503-516.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witztum, J.L.2
  • 3
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • Cardiogenics; CARDIoGRAM Consortium
    • Schunkert H, König IR, Kathiresan S, et al; Cardiogenics; CARDIoGRAM Consortium. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011;43:333-338.
    • (2011) Nat Genet , vol.43 , pp. 333-338
    • Schunkert, H.1    König, I.R.2    Kathiresan, S.3
  • 4
    • 79251619565 scopus 로고    scopus 로고
    • Addressing the complexity of cardiovascular disease by design
    • Lotta LA, Peyvandi F. Addressing the complexity of cardiovascular disease by design. Lancet. 2011;377:356-358.
    • (2011) Lancet , vol.377 , pp. 356-358
    • Lotta, L.A.1    Peyvandi, F.2
  • 5
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, Chanock SJ, Chatterjee N. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat Genet. 2010;42:570-575.
    • (2010) Nat Genet , vol.42 , pp. 570-575
    • Park, J.H.1    Wacholder, S.2    Gail, M.H.3    Peters, U.4    Jacobs, K.B.5    Chanock, S.J.6    Chatterjee, N.7
  • 6
    • 79956319051 scopus 로고    scopus 로고
    • Progress and challenges in translating the biology of atherosclerosis
    • Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature. 2011;473:317-325.
    • (2011) Nature , vol.473 , pp. 317-325
    • Libby, P.1    Ridker, P.M.2    Hansson, G.K.3
  • 9
    • 78449244161 scopus 로고    scopus 로고
    • Predict (personalized risk evaluation and diagnosis in the coronary tree) investigators. Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients
    • Rosenberg S, Elashoff MR, Beineke P, et al PREDICT (Personalized Risk Evaluation and Diagnosis in the Coronary Tree) Investigators. Multicenter validation of the diagnostic accuracy of a blood-based gene expression test for assessing obstructive coronary artery disease in nondiabetic patients. Ann Intern Med. 2010;153:425-434.
    • (2010) Ann Intern Med , vol.153 , pp. 425-434
    • Rosenberg, S.1    Elashoff, M.R.2    Beineke, P.3
  • 11
    • 60549111634 scopus 로고    scopus 로고
    • Wgcna: An r package for weighted correlation network analysis
    • Langfelder P, Horvath S. WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics. 2008;9:559.
    • (2008) BMC Bioinformatics , vol.9 , pp. 559
    • Langfelder, P.1    Horvath, S.2
  • 12
    • 77950339092 scopus 로고    scopus 로고
    • Integrating pathway analysis and genetics of gene expression for genome-wide association studies
    • Zhong H, Yang X, Kaplan LM, Molony C, Schadt EE. Integrating pathway analysis and genetics of gene expression for genome-wide association studies. Am J Hum Genet. 2010;86:581-591.
    • (2010) Am J Hum Genet , vol.86 , pp. 581-591
    • Zhong, H.1    Yang, X.2    Kaplan, L.M.3    Molony, C.4    Schadt, E.E.5
  • 13
    • 77953194222 scopus 로고    scopus 로고
    • Liver and adipose expression associated snps are enriched for association to type 2 diabetes
    • Zhong H, Beaulaurier J, Lum PY, et al. Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes. PLoS Genet. 2010;6:-e1000932.
    • (2010) PLoS Genet , vol.6
    • Zhong, H.1    Beaulaurier, J.2    Lum, P.Y.3
  • 14
    • 77955505564 scopus 로고    scopus 로고
    • Biological, clinical and population relevance of 95 loci for blood lipids
    • Teslovich TM, Musunuru K, Smith AV, et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature. 2010;466:707-713.
    • (2010) Nature , vol.466 , pp. 707-713
    • Teslovich, T.M.1    Musunuru, K.2    Smith, A.V.3
  • 15
    • 41349095280 scopus 로고    scopus 로고
    • Genetics of gene expression and its effect on disease
    • Emilsson V, Thorleifsson G, Zhang B, et al. Genetics of gene expression and its effect on disease. Nature. 2008;452:423-428.
    • (2008) Nature , vol.452 , pp. 423-428
    • Emilsson, V.1    Thorleifsson, G.2    Zhang, B.3
  • 16
    • 78650766485 scopus 로고    scopus 로고
    • Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse f2 intercross
    • Derry JM, Zhong H, Molony C, et al. Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross. PLoS One. 2010;5:-e14319.
    • (2010) PLoS One , vol.5
    • Derry, J.M.1    Zhong, H.2    Molony, C.3
  • 20
    • 77950214375 scopus 로고    scopus 로고
    • Altered metabolism and lipodystrophy in the early b-cell factor 1-deficient mouse
    • Fretz JA, Nelson T, Xi Y, Adams DJ, Rosen CJ, Horowitz MC. Altered metabolism and lipodystrophy in the early B-cell factor 1-deficient mouse. Endocrinology. 2010;151:1611-1621.
    • (2010) Endocrinology , vol.151 , pp. 1611-1621
    • Fretz, J.A.1    Nelson, T.2    Xi, Y.3    Adams, D.J.4    Rosen, C.J.5    Horowitz, M.C.6
  • 21
    • 79959824142 scopus 로고    scopus 로고
    • Multiple loci are associated with white blood cell phenotypes
    • Nalls MA, Couper DJ, Tanaka T, et al. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 2011;7:-e1002113.
    • (2011) PLoS Genet , vol.7
    • Nalls, M.A.1    Couper, D.J.2    Tanaka, T.3
  • 22
    • 49649091381 scopus 로고    scopus 로고
    • Proteolens: A visual analytic tool for multi-scale database-driven biological network data mining
    • Huan T, Sivachenko AY, Harrison SH, Chen JY. ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining. BMC Bioinformatics. 2008;9:S5.
    • (2008) BMC Bioinformatics , vol.9
    • Huan, T.1    Sivachenko, A.Y.2    Harrison, S.H.3    Chen, J.Y.4
  • 23
    • 40749105508 scopus 로고    scopus 로고
    • Variations in dna elucidate molecular networks that cause disease
    • Chen Y, Zhu J, Lum PY, et al. Variations in DNA elucidate molecular networks that cause disease. Nature. 2008;452:429-435.
    • (2008) Nature , vol.452 , pp. 429-435
    • Chen, Y.1    Zhu, J.2    Lum, P.Y.3
  • 24
    • 63449132586 scopus 로고    scopus 로고
    • Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
    • Yang X, Deignan JL, Qi H, et al. Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nat Genet. 2009;41:415-423.
    • (2009) Nat Genet , vol.41 , pp. 415-423
    • Yang, X.1    Deignan, J.L.2    Qi, H.3
  • 25
    • 77955003279 scopus 로고    scopus 로고
    • Identification and validation of genes affecting aortic lesions in mice
    • Yang X, Peterson L, Thieringer R, et al. Identification and validation of genes affecting aortic lesions in mice. J Clin Invest. 2010;120:2414-2422.
    • (2010) J Clin Invest , vol.120 , pp. 2414-2422
    • Yang, X.1    Peterson, L.2    Thieringer, R.3
  • 26
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A doubleedged sword
    • Hansson GK, Libby P. The immune response in atherosclerosis: a doubleedged sword. Nat Rev Immunol. 2006;6:508-519.
    • (2006) Nat Rev Immunol , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 27
    • 0036193513 scopus 로고    scopus 로고
    • Protective immunity against atherosclerosis carried by b cells of hypercholesterolemic mice
    • Caligiuri G, Nicoletti A, Poirier B, Hansson GK. Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice. J Clin Invest. 2002;109:745-753.
    • (2002) J Clin Invest , vol.109 , pp. 745-753
    • Caligiuri, G.1    Nicoletti, A.2    Poirier, B.3    Hansson, G.K.4
  • 28
    • 80053574700 scopus 로고    scopus 로고
    • B1a b lymphocytes are atheroprotective by secreting natural igm that increases igm deposits and reduces necrotic cores in atherosclerotic lesions
    • Kyaw T, Tay C, Krishnamurthi S, Kanellakis P, Agrotis A, Tipping P, Bobik A, Toh BH. B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions. Circ Res. 2011;109:830-840.
    • (2011) Circ Res , vol.109 , pp. 830-840
    • Kyaw, T.1    Tay, C.2    Krishnamurthi, S.3    Kanellakis, P.4    Agrotis, A.5    Tipping, P.6    Bobik, A.7    Toh, B.H.8
  • 31
    • 67349085063 scopus 로고    scopus 로고
    • Wellcome trust case control consortium. Genome-wide association study identifies eight loci associated with blood pressure
    • Newton-Cheh C, Johnson T, Gateva V, et al Wellcome Trust Case Control Consortium. Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet. 2009;41:666-676.
    • (2009) Nat Genet , vol.41 , pp. 666-676
    • Newton-Cheh, C.1    Johnson, T.2    Gateva, V.3
  • 33
    • 67349208839 scopus 로고    scopus 로고
    • Genome-wide association study of blood pressure and hypertension
    • Levy D, Ehret GB, Rice K, et al. Genome-wide association study of blood pressure and hypertension. Nat Genet. 2009;41:677-687.
    • (2009) Nat Genet , vol.41 , pp. 677-687
    • Levy, D.1    Ehret, G.B.2    Rice, K.3
  • 34
    • 78049337953 scopus 로고    scopus 로고
    • Magic; procardis consortium. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
    • Speliotes EK, Willer CJ, Berndt SI, et al MAGIC; Procardis Consortium. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet. 2010;42:937-948.
    • (2010) Nat Genet , vol.42 , pp. 937-948
    • Speliotes, E.K.1    Willer, C.J.2    Berndt, S.I.3
  • 35
    • 77954143522 scopus 로고    scopus 로고
    • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
    • MAGIC investigators; GIANT Consortium
    • Voight BF, Scott LJ, Steinthorsdottir V, et al; MAGIC investigators; GIANT Consortium. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet. 2010;42:579-589.
    • (2010) Nat Genet , vol.42 , pp. 579-589
    • Voight, B.F.1    Scott, L.J.2    Steinthorsdottir, V.3
  • 36
    • 77957342306 scopus 로고    scopus 로고
    • Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits
    • MAGIC investigators
    • Segrè AV, Groop L, Mootha VK, Daly MJ, Altshuler D; DIAGRAM Consortium; MAGIC investigators. Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 2010;6:-e1001058.
    • (2010) PLoS Genet , vol.6
    • Segrè, A.V.1    Groop, L.2    Mootha, V.K.3    Daly, M.J.4    Altshuler, D.5    Diagram, C.6
  • 38
    • 56649097558 scopus 로고    scopus 로고
    • Gsea-snp: Applying gene set enrichment analysis to snp data from genome-wide association studies
    • Holden M, Deng S, Wojnowski L, Kulle B. GSEA-SNP: applying gene set enrichment analysis to SNP data from genome-wide association studies. Bioinformatics. 2008;24:2784-2785.
    • (2008) Bioinformatics , vol.24 , pp. 2784-2785
    • Holden, M.1    Deng, S.2    Wojnowski, L.3    Kulle, B.4
  • 39
    • 85027951331 scopus 로고    scopus 로고
    • Adaptive immunity in atherosclerosis: Mechanisms and future therapeutic targets
    • Lahoute C, Herbin O, Mallat Z, Tedgui A. Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets. Nat Rev Cardiol. 2011;8:348-358.
    • (2011) Nat Rev Cardiol , vol.8 , pp. 348-358
    • Lahoute, C.1    Herbin, O.2    Mallat, Z.3    Tedgui, A.4


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