-
1
-
-
80051873375
-
CD8(+) T cells: foot soldiers of the immune system
-
doi: 10.1016/j.immuni.2011.07.010
-
Zhang N, Bevan MJ. CD8(+) T cells: foot soldiers of the immune system. Immunity (2011) 35:161-8. doi: 10.1016/j.immuni.2011.07.010
-
(2011)
Immunity
, vol.35
, pp. 161-168
-
-
Zhang, N.1
Bevan, M.J.2
-
2
-
-
78650970845
-
Innate or adaptive immunity? The example of natural killer cells
-
doi:10.1126/science.1198687
-
Vivier E, Raulet DH, Moretta A, Caligiuri MA, Zitvogel L, Lanier LL, et al. Innate or adaptive immunity? The example of natural killer cells. Science (2011) 331:44-9. doi:10.1126/science.1198687
-
(2011)
Science
, vol.331
, pp. 44-49
-
-
Vivier, E.1
Raulet, D.H.2
Moretta, A.3
Caligiuri, M.A.4
Zitvogel, L.5
Lanier, L.L.6
-
3
-
-
38449096740
-
Secretory mechanisms in cell-mediated cytotoxicity
-
doi:10.1146/annurev.cellbio.23.090506.123521
-
Stinchcombe JC, Griffiths GM. Secretory mechanisms in cell-mediated cytotoxicity. Annu Rev Cell Dev Biol (2007) 23:495-517. doi:10.1146/annurev.cellbio.23.090506.123521
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 495-517
-
-
Stinchcombe, J.C.1
Griffiths, G.M.2
-
4
-
-
42449102990
-
Up on the tightrope: natural killer cell activation and inhibition
-
doi:10.1038/ni1581
-
Lanier LL. Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol (2008) 9:495-502. doi:10.1038/ni1581
-
(2008)
Nat Immunol
, vol.9
, pp. 495-502
-
-
Lanier, L.L.1
-
5
-
-
84875528678
-
Controlling natural killer cell responses: integration of signals for activation and inhibition
-
doi:10.1146/annurev-immunol-020711-075005
-
Long EO, Sik Kim H, Liu D, Peterson ME, Rajagopalan S. Controlling natural killer cell responses: integration of signals for activation and inhibition. Annu Rev Immunol (2013) 31:227-58. doi:10.1146/annurev-immunol-020711-075005
-
(2013)
Annu Rev Immunol
, vol.31
, pp. 227-258
-
-
Long, E.O.1
Sik Kim, H.2
Liu, D.3
Peterson, M.E.4
Rajagopalan, S.5
-
6
-
-
0345060886
-
The mature activating natural killer cell immunologic synapse is formed in distinct stages
-
doi:10.1073/pnas.1835830100
-
Orange JS, Harris KE, Andzelm MM, Valter MM, Geha RS, Strominger JL. The mature activating natural killer cell immunologic synapse is formed in distinct stages. Proc Natl Acad Sci U S A (2003) 100:14151-6. doi:10.1073/pnas.1835830100
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 14151-14156
-
-
Orange, J.S.1
Harris, K.E.2
Andzelm, M.M.3
Valter, M.M.4
Geha, R.S.5
Strominger, J.L.6
-
7
-
-
2442651482
-
T cell killing does not require the formation of a stable mature immunological synapse
-
doi:10.1038/ni0604-658a
-
Purbhoo MA, Irvine DJ, Huppa JB, Davis MM. T cell killing does not require the formation of a stable mature immunological synapse. Nat Immunol (2004) 5:524-30. doi:10.1038/ni0604-658a
-
(2004)
Nat Immunol
, vol.5
, pp. 524-530
-
-
Purbhoo, M.A.1
Irvine, D.J.2
Huppa, J.B.3
Davis, M.M.4
-
8
-
-
33746655745
-
Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses
-
doi:10.1073/pnas.0600651103
-
Wiedemann A, Depoil D, Faroudi M, Valitutti S. Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses. Proc Natl Acad Sci U S A (2006) 103:10985-90. doi:10.1073/pnas.0600651103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10985-10990
-
-
Wiedemann, A.1
Depoil, D.2
Faroudi, M.3
Valitutti, S.4
-
9
-
-
70349751654
-
Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain
-
doi:10.1016/j.immuni.2009.09.004
-
Beal AM, Anikeeva N, Varma R, Cameron TO, Vasiliver-Shamis G, Norris PJ, et al. Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain. Immunity (2009) 31:632-42. doi:10.1016/j.immuni.2009.09.004
-
(2009)
Immunity
, vol.31
, pp. 632-642
-
-
Beal, A.M.1
Anikeeva, N.2
Varma, R.3
Cameron, T.O.4
Vasiliver-Shamis, G.5
Norris, P.J.6
-
10
-
-
77958513926
-
Intravital imaging reveals distinct dynamics for natural killer and CD8(+) T cells during tumor regression
-
doi:10.1016/j.immuni.2010.09.016
-
Deguine J, Breart B, Lemaître F, Di Santo JP, Bousso P. Intravital imaging reveals distinct dynamics for natural killer and CD8(+) T cells during tumor regression. Immunity (2010) 33:632-44. doi:10.1016/j.immuni.2010.09.016
-
(2010)
Immunity
, vol.33
, pp. 632-644
-
-
Deguine, J.1
Breart, B.2
Lemaître, F.3
Di Santo, J.P.4
Bousso, P.5
-
11
-
-
0035655587
-
The immunological synapse of CTL contains a secretory domain and membrane bridges
-
doi:10.1016/S1074-7613(01)00234-5
-
Stinchcombe JC, Bossi G, Booth S, Griffiths GM. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity (2001) 5:751-61. doi:10.1016/S1074-7613(01)00234-5
-
(2001)
Immunity
, vol.5
, pp. 751-761
-
-
Stinchcombe, J.C.1
Bossi, G.2
Booth, S.3
Griffiths, G.M.4
-
12
-
-
80053325995
-
Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy
-
doi:10.1371/journal.pbio.1001152
-
Brown AC, Oddos S, Dobbie IM, Alakoskela JM, Parton RM, Eissmann P, et al. Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy. PLoS Biol (2011) 9:e1001152. doi:10.1371/journal.pbio.1001152
-
(2011)
PLoS Biol
, vol.9
-
-
Brown, A.C.1
Oddos, S.2
Dobbie, I.M.3
Alakoskela, J.M.4
Parton, R.M.5
Eissmann, P.6
-
13
-
-
80053321288
-
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse
-
doi:10.1371/journal.pbio.1001151
-
Rak GD, Mace EM, Banerjee PP, Svitkina T, Orange JS. Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse. PLoS Biol (2011) 9:e1001151. doi:10.1371/journal.pbio.1001151
-
(2011)
PLoS Biol
, vol.9
-
-
Rak, G.D.1
Mace, E.M.2
Banerjee, P.P.3
Svitkina, T.4
Orange, J.S.5
-
14
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
doi:10.1016/j.immuni.2006.04.010
-
Varma R, Campi G, Yokosuka T, Saito T, Dustin ML. T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity (2006) 25:117-27. doi:10.1016/j.immuni.2006.04.010
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
15
-
-
79951911283
-
Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells
-
doi:10.1083/jcb.201009135
-
Abeyweera TP, Merino E, Huse M. Inhibitory signaling blocks activating receptor clustering and induces cytoskeletal retraction in natural killer cells. J Cell Biol (2011) 192:675-90. doi:10.1083/jcb.201009135
-
(2011)
J Cell Biol
, vol.192
, pp. 675-690
-
-
Abeyweera, T.P.1
Merino, E.2
Huse, M.3
-
16
-
-
84864139002
-
Integration of the movement of signaling microclusters with cellular motility in immunological synapses
-
doi:10.1038/ni.2364
-
Beemiller P, Jacobelli J, Krummel MF. Integration of the movement of signaling microclusters with cellular motility in immunological synapses. Nat Immunol (2012) 13:787-95. doi:10.1038/ni.2364
-
(2012)
Nat Immunol
, vol.13
, pp. 787-795
-
-
Beemiller, P.1
Jacobelli, J.2
Krummel, M.F.3
-
17
-
-
84863992208
-
F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation
-
doi:10.1083/jcb.201201018
-
Babich A, Li S, O'Connor RS, Milone MC, Freedman BD, Burkhardt JK. F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation. J Cell Biol (2012) 197:775-87. doi:10.1083/jcb.201201018
-
(2012)
J Cell Biol
, vol.197
, pp. 775-787
-
-
Babich, A.1
Li, S.2
O'Connor, R.S.3
Milone, M.C.4
Freedman, B.D.5
Burkhardt, J.K.6
-
18
-
-
25844464180
-
Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells
-
doi:10.1084/jem.20051143
-
Bryceson YT, March ME, Barber DF, Ljunggren HG, Long EO. Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J Exp Med (2005) 202:1001-12. doi:10.1084/jem.20051143
-
(2005)
J Exp Med
, vol.202
, pp. 1001-1012
-
-
Bryceson, Y.T.1
March, M.E.2
Barber, D.F.3
Ljunggren, H.G.4
Long, E.O.5
-
19
-
-
68049118970
-
Natural killer cell signal integration balances synapse symmetry and migration
-
doi:10.1371/journal.pbio.1000159
-
Culley FJ, Johnson M, Evans JH, Kumar S, Crilly R, Casasbuenas J, et al. Natural killer cell signal integration balances synapse symmetry and migration. PLoS Biol (2009) 7:e1000159. doi:10.1371/journal.pbio.1000159
-
(2009)
PLoS Biol
, vol.7
-
-
Culley, F.J.1
Johnson, M.2
Evans, J.H.3
Kumar, S.4
Crilly, R.5
Casasbuenas, J.6
-
20
-
-
18144426450
-
Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes
-
doi:10.1073/pnas.0502467102
-
Anikeeva N, Somersalo K, Sims TN, Thomas VK, Dustin ML, Sykulev Y. Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (2005) 102:6437-42. doi:10.1073/pnas.0502467102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 6437-6442
-
-
Anikeeva, N.1
Somersalo, K.2
Sims, T.N.3
Thomas, V.K.4
Dustin, M.L.5
Sykulev, Y.6
-
21
-
-
77951020111
-
Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state
-
doi:10.1182/blood-2009-07-235804
-
Stabile H, Carlino C, Mazza C, Giliani S, Morrone S, Notarangelo LD, et al. Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity state. Blood (2010) 115:2818-26. doi:10.1182/blood-2009-07-235804
-
(2010)
Blood
, vol.115
, pp. 2818-2826
-
-
Stabile, H.1
Carlino, C.2
Mazza, C.3
Giliani, S.4
Morrone, S.5
Notarangelo, L.D.6
-
22
-
-
82555196507
-
A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse
-
doi:10.1126/scisignal.2001729
-
Carlin LM, Evans R, Milewicz H, Fernandes L, Matthews DR, Perani M. A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse. Sci Signal (2011) 4:ra81. doi:10.1126/scisignal.2001729
-
(2011)
Sci Signal
, vol.4
-
-
Carlin, L.M.1
Evans, R.2
Milewicz, H.3
Fernandes, L.4
Matthews, D.R.5
Perani, M.6
-
23
-
-
0037143734
-
Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses
-
doi:10.1073/pnas.162376099
-
Orange JS, Ramesh N, Remold-O'Donnell E, Sasahara Y, Koopman L, Byrne M, et al. Wiskott-Aldrich syndrome protein is required for NK cell cytotoxicity and colocalizes with actin to NK cell-activating immunologic synapses. Proc Natl Acad Sci U S A (2002) 99:11351-6. doi:10.1073/pnas.162376099
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11351-11356
-
-
Orange, J.S.1
Ramesh, N.2
Remold-O'Donnell, E.3
Sasahara, Y.4
Koopman, L.5
Byrne, M.6
-
24
-
-
3142585003
-
Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect
-
doi:10.1182/blood-2003-07-2621
-
Gismondi A, Cifaldi L, Mazza C, Giliani S, Parolini S, Morrone S, et al. Impaired natural and CD16-mediated NK cell cytotoxicity in patients with WAS and XLT: ability of IL-2 to correct NK cell functional defect. Blood (2004) 104:436-43. doi:10.1182/blood-2003-07-2621
-
(2004)
Blood
, vol.104
, pp. 436-443
-
-
Gismondi, A.1
Cifaldi, L.2
Mazza, C.3
Giliani, S.4
Parolini, S.5
Morrone, S.6
-
25
-
-
70450248424
-
Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity
-
doi:10.1016/j.cub.2009.10.029
-
Butler B, Cooper JA. Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity. Curr Biol (2009) 19:1886-96. doi:10.1016/j.cub.2009.10.029
-
(2009)
Curr Biol
, vol.19
, pp. 1886-1896
-
-
Butler, B.1
Cooper, J.A.2
-
26
-
-
78649617600
-
The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets
-
doi:10.1189/jlb.0410197
-
De Meester J, Calvez R, Valitutti S, Dupré L. The Wiskott-Aldrich syndrome protein regulates CTL cytotoxicity and is required for efficient killing of B cell lymphoma targets. J Leukoc Biol (2010) 88:1031-40. doi:10.1189/jlb.0410197
-
(2010)
J Leukoc Biol
, vol.88
, pp. 1031-1040
-
-
De Meester, J.1
Calvez, R.2
Valitutti, S.3
Dupré, L.4
-
27
-
-
43249090885
-
PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway
-
doi:10.1182/blood-2007-08-108886
-
Micucci F, Capuano C, Marchetti E, Piccoli M, Frati L, Santoni A, et al. PI5KI-dependent signals are critical regulators of the cytolytic secretory pathway. Blood (2008) 111:4165-72. doi:10.1182/blood-2007-08-108886
-
(2008)
Blood
, vol.111
, pp. 4165-4172
-
-
Micucci, F.1
Capuano, C.2
Marchetti, E.3
Piccoli, M.4
Frati, L.5
Santoni, A.6
-
28
-
-
60549106555
-
A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells
-
Mace EM, Monkley SJ, Critchley DR, Takei F. A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells. J Immunol (2009) 182:948-56.
-
(2009)
J Immunol
, vol.182
, pp. 948-956
-
-
Mace, E.M.1
Monkley, S.J.2
Critchley, D.R.3
Takei, F.4
-
29
-
-
33749185296
-
Centrosome polarization delivers secretory granules to the immunological synapse
-
doi:10.1038/nature05071
-
Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM. Centrosome polarization delivers secretory granules to the immunological synapse. Nature (2006) 443:462-5. doi:10.1038/nature05071
-
(2006)
Nature
, vol.443
, pp. 462-465
-
-
Stinchcombe, J.C.1
Majorovits, E.2
Bossi, G.3
Fuller, S.4
Griffiths, G.M.5
-
30
-
-
79959574557
-
Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems
-
doi:10.1186/1741-7007-9-45
-
Stinchcombe JC, Salio M, Cerundolo V, Pende D, Arico M, Griffiths GM. Centriole polarisation to the immunological synapse directs secretion from cytolytic cells of both the innate and adaptive immune systems. BMC Biol (2011) 9:45. doi:10.1186/1741-7007-9-45
-
(2011)
BMC Biol
, vol.9
, pp. 45
-
-
Stinchcombe, J.C.1
Salio, M.2
Cerundolo, V.3
Pende, D.4
Arico, M.5
Griffiths, G.M.6
-
31
-
-
79958765719
-
A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes
-
doi:10.1111/j.1600-0854.2011.01194.x
-
Daniele T, Hackmann Y, Ritter AT, Wenham M, Booth S, Bossi G, et al. A role for Rab7 in the movement of secretory granules in cytotoxic T lymphocytes. Traffic (2011) 12:902-11. doi:10.1111/j.1600-0854.2011.01194.x
-
(2011)
Traffic
, vol.12
, pp. 902-911
-
-
Daniele, T.1
Hackmann, Y.2
Ritter, A.T.3
Wenham, M.4
Booth, S.5
Bossi, G.6
-
32
-
-
77954197189
-
Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment
-
doi:10.1091/mbc.E09-11-0930
-
Mentlik AN, Sanborn KB, Holzbaur EL, Orange JS. Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment. Mol Biol Cell (2010) 21:2241-56. doi:10.1091/mbc.E09-11-0930
-
(2010)
Mol Biol Cell
, vol.21
, pp. 2241-2256
-
-
Mentlik, A.N.1
Sanborn, K.B.2
Holzbaur, E.L.3
Orange, J.S.4
-
33
-
-
84860330652
-
Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex
-
doi:10.1182/blood-2011-09-382556
-
Kurowska M, Goudin N, Nehme NT, Court M, Garin J, Fischer A, et al. Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex. Blood (2012) 119:3879-89. doi:10.1182/blood-2011-09-382556
-
(2012)
Blood
, vol.119
, pp. 3879-3889
-
-
Kurowska, M.1
Goudin, N.2
Nehme, N.T.3
Court, M.4
Garin, J.5
Fischer, A.6
-
34
-
-
84876061817
-
An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse
-
doi:10.1073/pnas.1218640110
-
Bertrand F, Müller S, Roh KH, Laurent C, Dupré L, Valitutti S. An initial and rapid step of lytic granule secretion precedes microtubule organizing center polarization at the cytotoxic T lymphocyte/target cell synapse. Proc Natl Acad Sci U S A (2013) 110:6073-8. doi:10.1073/pnas.1218640110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 6073-6078
-
-
Bertrand, F.1
Müller, S.2
Roh, K.H.3
Laurent, C.4
Dupré, L.5
Valitutti, S.6
-
35
-
-
34948877989
-
Myosin IIA is required for cytolytic granule exocytosis in human NK cells
-
doi:10.1084/jem.20071143
-
Andzelm MM, Chen X, Krzewski K, Orange JS, Strominger JL. Myosin IIA is required for cytolytic granule exocytosis in human NK cells. J Exp Med (2007) 204:2285-91. doi:10.1084/jem.20071143
-
(2007)
J Exp Med
, vol.204
, pp. 2285-2291
-
-
Andzelm, M.M.1
Chen, X.2
Krzewski, K.3
Orange, J.S.4
Strominger, J.L.5
-
36
-
-
82155184487
-
Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity
-
doi:10.1182/blood-2011-03-344846
-
Sanborn KB, Mace EM, Rak GD, Difeo A, Martignetti JA, Pecci A, et al. Phosphorylation of the myosin IIA tailpiece regulates single myosin IIA molecule association with lytic granules to promote NK-cell cytotoxicity. Blood (2011) 118:5862-71. doi:10.1182/blood-2011-03-344846
-
(2011)
Blood
, vol.118
, pp. 5862-5871
-
-
Sanborn, K.B.1
Mace, E.M.2
Rak, G.D.3
Difeo, A.4
Martignetti, J.A.5
Pecci, A.6
-
37
-
-
84880381626
-
Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II
-
doi:10.1073/pnas.1306180110
-
Liu X, Kapoor TM, Chen JK, Huse M. Diacylglycerol promotes centrosome polarization in T cells via reciprocal localization of dynein and myosin II. Proc Natl Acad Sci U S A (2013) 110:11976-81. doi:10.1073/pnas.1306180110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 11976-11981
-
-
Liu, X.1
Kapoor, T.M.2
Chen, J.K.3
Huse, M.4
-
38
-
-
67449141628
-
Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse
-
doi:10.4049/jimmunol.0804337
-
Sanborn KB, Rak GD, Maru SY, Demers K, Difeo A, Martignetti JA, et al. Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse. J Immunol (2009) 182:6969-84. doi:10.4049/jimmunol.0804337
-
(2009)
J Immunol
, vol.182
, pp. 6969-6984
-
-
Sanborn, K.B.1
Rak, G.D.2
Maru, S.Y.3
Demers, K.4
Difeo, A.5
Martignetti, J.A.6
-
39
-
-
79952768718
-
β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells
-
doi:10.4049/jimmunol.1002438
-
March ME, Long EO. β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells. J Immunol (2011) 186:2998-3005. doi:10.4049/jimmunol.1002438
-
(2011)
J Immunol
, vol.186
, pp. 2998-3005
-
-
March, M.E.1
Long, E.O.2
-
40
-
-
79951859367
-
Centrosome docking at the immunological synapse is controlled by Lck signaling
-
doi:10.1083/jcb.201008140
-
Tsun A, Qureshi I, Stinchcombe JC, Jenkins MR, de la Roche M, Kleczkowska J, et al. Centrosome docking at the immunological synapse is controlled by Lck signaling. J Cell Biol (2011) 192:663-74. doi:10.1083/jcb.201008140
-
(2011)
J Cell Biol
, vol.192
, pp. 663-674
-
-
Tsun, A.1
Qureshi, I.2
Stinchcombe, J.C.3
Jenkins, M.R.4
de la Roche, M.5
Kleczkowska, J.6
-
41
-
-
84878250013
-
Rapid activation receptor-or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling
-
doi:10.1182/blood-2012-06-437012
-
James AM, Hsu HT, Dongre P, Uzel G, Mace EM, Banerjee PP, et al. Rapid activation receptor-or IL-2-induced lytic granule convergence in human natural killer cells requires Src, but not downstream signaling. Blood (2013) 121:2627-37. doi:10.1182/blood-2012-06-437012
-
(2013)
Blood
, vol.121
, pp. 2627-2637
-
-
James, A.M.1
Hsu, H.T.2
Dongre, P.3
Uzel, G.4
Mace, E.M.5
Banerjee, P.P.6
-
42
-
-
0031573231
-
Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells
-
Gismondi A, Bisogno L, Mainiero F, Palmieri G, Piccoli M, Frati L, et al. Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells. J Immunol (1997) 159:4729-36.
-
(1997)
J Immunol
, vol.159
, pp. 4729-4736
-
-
Gismondi, A.1
Bisogno, L.2
Mainiero, F.3
Palmieri, G.4
Piccoli, M.5
Frati, L.6
-
43
-
-
0034640839
-
The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing
-
doi:10.1083/jcb.149.6.1249
-
Sancho D, Nieto M, Llano M, Rodríguez-Fernández JL, Tejedor R, Avraham S, et al. The tyrosine kinase PYK-2/RAFTK regulates natural killer (NK) cell cytotoxic response, and is translocated and activated upon specific target cell recognition and killing. J Cell Biol (2000) 149:1249-62. doi:10.1083/jcb.149.6.1249
-
(2000)
J Cell Biol
, vol.149
, pp. 1249-1262
-
-
Sancho, D.1
Nieto, M.2
Llano, M.3
Rodríguez-Fernández, J.L.4
Tejedor, R.5
Avraham, S.6
-
44
-
-
82755190061
-
Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation
-
doi:10.4049/jimmunol.1003690
-
Robertson LK, Ostergaard HL. Paxillin associates with the microtubule cytoskeleton and the immunological synapse of CTL through its leucine-aspartic acid domains and contributes to microtubule organizing center reorientation. J Immunol (2011) 187:5824-33. doi:10.4049/jimmunol.1003690
-
(2011)
J Immunol
, vol.187
, pp. 5824-5833
-
-
Robertson, L.K.1
Ostergaard, H.L.2
-
45
-
-
67349243386
-
Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells
-
doi:10.1038/ni.1734
-
Quann EJ, Merino E, Furuta T, Huse M. Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells. Nat Immunol (2009) 10:627-35. doi:10.1038/ni.1734
-
(2009)
Nat Immunol
, vol.10
, pp. 627-635
-
-
Quann, E.J.1
Merino, E.2
Furuta, T.3
Huse, M.4
-
46
-
-
0038445896
-
Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization
-
Kuhné MR, Lin J, Yablonski D, Mollenauer MN, Ehrlich LI, Huppa J, et al. Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization. J Immunol (2003) 171:860-6.
-
(2003)
J Immunol
, vol.171
, pp. 860-866
-
-
Kuhné, M.R.1
Lin, J.2
Yablonski, D.3
Mollenauer, M.N.4
Ehrlich, L.I.5
Huppa, J.6
-
47
-
-
58149300245
-
Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity
-
Ma JS, Haydar TF, Radoja S. Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity. J Immunol (2008) 181: 4716-22.
-
(2008)
J Immunol
, vol.181
, pp. 4716-4722
-
-
Ma, J.S.1
Haydar, T.F.2
Radoja, S.3
-
48
-
-
33645737558
-
Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling
-
doi:10.1083/jcb.200509076
-
Krzewski K, Chen X, Orange JS, Strominger JL. Formation of a WIP-, WASp-, actin-, and myosin IIA-containing multiprotein complex in activated NK cells and its alteration by KIR inhibitory signaling. J Cell Biol (2006) 173:121-32. doi:10.1083/jcb.200509076
-
(2006)
J Cell Biol
, vol.173
, pp. 121-132
-
-
Krzewski, K.1
Chen, X.2
Orange, J.S.3
Strominger, J.L.4
-
49
-
-
40649091406
-
WIP is essential for lytic granule polarization and NK cell cytotoxicity
-
doi:10.1073/pnas.0711593105
-
Krzewski K, Chen X, Strominger JL. WIP is essential for lytic granule polarization and NK cell cytotoxicity. Proc Natl Acad Sci U S A (2008) 105:2568-73. doi:10.1073/pnas.0711593105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2568-2573
-
-
Krzewski, K.1
Chen, X.2
Strominger, J.L.3
-
50
-
-
0035975946
-
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors
-
doi:10.1016/S0960-9822(01)00531-0
-
Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, et al. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr Biol (2001) 1:1680-5. doi:10.1016/S0960-9822(01)00531-0
-
(2001)
Curr Biol
, vol.1
, pp. 1680-1685
-
-
Jordens, I.1
Fernandez-Borja, M.2
Marsman, M.3
Dusseljee, S.4
Janssen, L.5
Calafat, J.6
-
51
-
-
34948842343
-
Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse
-
doi:10.1084/jem.20061893
-
Banerjee PP, Pandey R, Zheng R, Suhoski MM, Monaco-Shawver L, Orange JS. Cdc42-interacting protein-4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse. J Exp Med (2007) 204:2305-20. doi:10.1084/jem.20061893
-
(2007)
J Exp Med
, vol.204
, pp. 2305-2320
-
-
Banerjee, P.P.1
Pandey, R.2
Zheng, R.3
Suhoski, M.M.4
Monaco-Shawver, L.5
Orange, J.S.6
-
52
-
-
0034330547
-
Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
-
doi:10.1038/80859
-
Jiang K, Zhong B, Gilvary DL, Corliss BC, Hong-Geller E, Wei S, et al. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. Nat Immunol (2000) 1:419-25. doi:10.1038/80859
-
(2000)
Nat Immunol
, vol.1
, pp. 419-425
-
-
Jiang, K.1
Zhong, B.2
Gilvary, D.L.3
Corliss, B.C.4
Hong-Geller, E.5
Wei, S.6
-
53
-
-
33746901647
-
Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics
-
Graham DB, Cella M, Giurisato E, Fujikawa K, Miletic AV, Kloeppel T, et al. Vav1 controls DAP10-mediated natural cytotoxicity by regulating actin and microtubule dynamics. J Immunol (2006) 177:2349-55.
-
(2006)
J Immunol
, vol.177
, pp. 2349-2355
-
-
Graham, D.B.1
Cella, M.2
Giurisato, E.3
Fujikawa, K.4
Miletic, A.V.5
Kloeppel, T.6
-
54
-
-
67449123032
-
PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion
-
doi:10.4049/jimmunol.0803840
-
Segovis CM, Schoon RA, Dick CJ, Nacusi LP, Leibson PJ, Billadeau DD. PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion. J Immunol (2009) 182:6933-42. doi:10.4049/jimmunol.0803840
-
(2009)
J Immunol
, vol.182
, pp. 6933-6942
-
-
Segovis, C.M.1
Schoon, R.A.2
Dick, C.J.3
Nacusi, L.P.4
Leibson, P.J.5
Billadeau, D.D.6
-
55
-
-
33745882375
-
CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells
-
doi:10.1073/pnas.0604236103
-
Chen X, Allan DS, Krzewski K, Ge B, Kopcow H, Strominger JL. CD28-stimulated ERK2 phosphorylation is required for polarization of the microtubule organizing center and granules in YTS NK cells. Proc Natl Acad Sci U S A (2006) 103:10346-51. doi:10.1073/pnas.0604236103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10346-10351
-
-
Chen, X.1
Allan, D.S.2
Krzewski, K.3
Ge, B.4
Kopcow, H.5
Strominger, J.L.6
-
56
-
-
29144503720
-
A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation
-
Robertson LK, Mireau LR, Ostergaard HL. A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation. J Immunol (2005) 175:8138-45.
-
(2005)
J Immunol
, vol.175
, pp. 8138-8145
-
-
Robertson, L.K.1
Mireau, L.R.2
Ostergaard, H.L.3
-
57
-
-
84868549451
-
Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins
-
doi:10.1182/blood-2012-05-429977
-
Brown AC, Dobbie IM, Alakoskela JM, Davis I, Davis DM. Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins. Blood (2012) 120:3729-40. doi:10.1182/blood-2012-05-429977
-
(2012)
Blood
, vol.120
, pp. 3729-3740
-
-
Brown, A.C.1
Dobbie, I.M.2
Alakoskela, J.M.3
Davis, I.4
Davis, D.M.5
-
58
-
-
0032479968
-
The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing
-
doi:10.1084/jem.188.3.549
-
Billadeau DD, Brumbaugh KM, Dick CJ, Schoon RA, Bustelo XR, Leibson PJ. The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing. J Exp Med (1998) 188:549-59. doi:10.1084/jem.188.3.549
-
(1998)
J Exp Med
, vol.188
, pp. 549-559
-
-
Billadeau, D.D.1
Brumbaugh, K.M.2
Dick, C.J.3
Schoon, R.A.4
Bustelo, X.R.5
Leibson, P.J.6
-
59
-
-
0033559142
-
Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK cell cytotoxicity
-
Galandrini R, Palmieri G, Piccoli M, Frati L, Santoni A. Role for the Rac1 exchange factor Vav in the signaling pathways leading to NK cell cytotoxicity. J Immunol (1999) 162:3148-52.
-
(1999)
J Immunol
, vol.162
, pp. 3148-3152
-
-
Galandrini, R.1
Palmieri, G.2
Piccoli, M.3
Frati, L.4
Santoni, A.5
-
60
-
-
84868527546
-
NK cell lytic granules are highly motile at the immunological synapse and require F-actin for post-degranulation persistence
-
doi:10.4049/jimmunol.1201296
-
Mace EM, Wu WW, Ho T, Mann SS, Hsu HT, Orange JS. NK cell lytic granules are highly motile at the immunological synapse and require F-actin for post-degranulation persistence. J Immunol (2012) 189:4870-80. doi:10.4049/jimmunol.1201296
-
(2012)
J Immunol
, vol.189
, pp. 4870-4880
-
-
Mace, E.M.1
Wu, W.W.2
Ho, T.3
Mann, S.S.4
Hsu, H.T.5
Orange, J.S.6
-
61
-
-
0035911160
-
Rab27a is required for regulated secretion in cytotoxic T lymphocytes
-
doi:10.1083/jcb.152.4.825
-
Stinchcombe JC, Barral DC, Mules EH, Booth S, Hume AN, MacHesky LM, et al. Rab27a is required for regulated secretion in cytotoxic T lymphocytes. J Cell Biol (2001) 152:825-34. doi:10.1083/jcb.152.4.825
-
(2001)
J Cell Biol
, vol.152
, pp. 825-834
-
-
Stinchcombe, J.C.1
Barral, D.C.2
Mules, E.H.3
Booth, S.4
Hume, A.N.5
MacHesky, L.M.6
-
62
-
-
12944255844
-
A mutation in Rab27a causes the vesicle transport defects observed in ashen mice
-
doi:10.1073/pnas.140212797
-
Wilson SM, Yip R, Swing DA, O'Sullivan TN, Zhang Y, Novak EK, et al. A mutation in Rab27a causes the vesicle transport defects observed in ashen mice. Proc Natl Acad Sci U S A (2000) 97:7933-8. doi:10.1073/pnas.140212797
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7933-7938
-
-
Wilson, S.M.1
Yip, R.2
Swing, D.A.3
O'Sullivan, T.N.4
Zhang, Y.5
Novak, E.K.6
-
63
-
-
0344002689
-
Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
-
doi:10.1038/76024
-
Ménasché G, Pastural E, Feldmann J, Certain S, Ersoy F, Dupuis S, et al. Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome. Nat Genet (2000) 25:173-6. doi:10.1038/76024
-
(2000)
Nat Genet
, vol.25
, pp. 173-176
-
-
Ménasché, G.1
Pastural, E.2
Feldmann, J.3
Certain, S.4
Ersoy, F.5
Dupuis, S.6
-
64
-
-
58149388232
-
A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion
-
doi:10.1182/blood-2008-02-141069
-
Ménasché G, Ménager MM, Lefebvre JM, Deutsch E, Athman R, Lambert N, et al. A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion. Blood (2008) 112:5052-62. doi:10.1182/blood-2008-02-141069
-
(2008)
Blood
, vol.112
, pp. 5052-5062
-
-
Ménasché, G.1
Ménager, M.M.2
Lefebvre, J.M.3
Deutsch, E.4
Athman, R.5
Lambert, N.6
-
65
-
-
40449092959
-
Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse
-
doi:10.1111/j.1600-0854.2008.00714.x
-
Holt O, Kanno E, Bossi G, Booth S, Daniele T, Santoro A, et al. Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. Traffic (2008) 9:446-57. doi:10.1111/j.1600-0854.2008.00714.x
-
(2008)
Traffic
, vol.9
, pp. 446-457
-
-
Holt, O.1
Kanno, E.2
Bossi, G.3
Booth, S.4
Daniele, T.5
Santoro, A.6
-
66
-
-
34248370215
-
NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome
-
doi:10.1182/blood-2006-09-047159
-
Gazit R, Aker M, Elboim M, Achdout H, Katz G, Wolf DG, et al. NK cytotoxicity mediated by CD16 but not by NKp30 is functional in Griscelli syndrome. Blood (2007) 109:4306-12. doi:10.1182/blood-2006-09-047159
-
(2007)
Blood
, vol.109
, pp. 4306-4312
-
-
Gazit, R.1
Aker, M.2
Elboim, M.3
Achdout, H.4
Katz, G.5
Wolf, D.G.6
-
67
-
-
72949100151
-
Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity
-
doi:10.1182/blood-2009-06-225359
-
Wood SM, Meeths M, Chiang SC, Bechensteen AG, Boelens JJ, Heilmann C, et al. Different NK cell-activating receptors preferentially recruit Rab27a or Munc13-4 to perforin-containing granules for cytotoxicity. Blood (2009) 114:4117-27. doi:10.1182/blood-2009-06-225359
-
(2009)
Blood
, vol.114
, pp. 4117-4127
-
-
Wood, S.M.1
Meeths, M.2
Chiang, S.C.3
Bechensteen, A.G.4
Boelens, J.J.5
Heilmann, C.6
-
68
-
-
10744224641
-
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
-
doi:10.1016/S0092-8674(03)00855-9
-
Feldmann J, Callebaut I, Raposo G, Certain S, Bacq D, Dumont C, et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell (2003) 115:461-73. doi:10.1016/S0092-8674(03)00855-9
-
(2003)
Cell
, vol.115
, pp. 461-473
-
-
Feldmann, J.1
Callebaut, I.2
Raposo, G.3
Certain, S.4
Bacq, D.5
Dumont, C.6
-
69
-
-
33749349937
-
Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease
-
doi:10.1182/blood-2006-04-015693
-
Marcenaro S, Gallo F, Martini S, Santoro A, Griffiths GM, Aricó M, et al. Analysis of natural killer-cell function in familial hemophagocytic lymphohistiocytosis (FHL): defective CD107a surface expression heralds Munc13-4 defect and discriminates between genetic subtypes of the disease. Blood (2006) 108:2316-23. doi:10.1182/blood-2006-04-015693
-
(2006)
Blood
, vol.108
, pp. 2316-2323
-
-
Marcenaro, S.1
Gallo, F.2
Martini, S.3
Santoro, A.4
Griffiths, G.M.5
Aricó, M.6
-
70
-
-
80051639052
-
The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane
-
doi:10.1182/blood-2011-02-339523
-
Elstak ED, Neeft M, Nehme NT, Voortman J, Cheung M, Goodarzifard M, et al. The munc13-4-rab27 complex is specifically required for tethering secretory lysosomes at the plasma membrane. Blood (2011) 118:1570-8. doi:10.1182/blood-2011-02-339523
-
(2011)
Blood
, vol.118
, pp. 1570-1578
-
-
Elstak, E.D.1
Neeft, M.2
Nehme, N.T.3
Voortman, J.4
Cheung, M.5
Goodarzifard, M.6
-
71
-
-
72849125357
-
Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells
-
doi:10.1172/JCI40732
-
Côte M, Ménager MM, Burgess A, Mahlaoui N, Picard C, Schaffner C, et al. Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells. J Clin Invest (2009) 119:3765-73. doi:10.1172/JCI40732
-
(2009)
J Clin Invest
, vol.119
, pp. 3765-3773
-
-
Côte, M.1
Ménager, M.M.2
Burgess, A.3
Mahlaoui, N.4
Picard, C.5
Schaffner, C.6
-
72
-
-
29944442846
-
Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A
-
doi:10.1002/humu.20274
-
Zur Stadt U, Beutel K, Kolberg S, Schneppenheim R, Kabisch H, Janka G, et al. Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A. Hum Mutat (2006) 27:62-8. doi:10.1002/humu.20274
-
(2006)
Hum Mutat
, vol.27
, pp. 62-68
-
-
Zur Stadt, U.1
Beutel, K.2
Kolberg, S.3
Schneppenheim, R.4
Kabisch, H.5
Janka, G.6
-
73
-
-
34548814973
-
Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
-
doi:10.1182/blood-2007-02-074468
-
Bryceson YT, Rudd E, Zheng C, Edner J, Ma D, Wood SM, et al. Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood (2007) 110:1906-15. doi:10.1182/blood-2007-02-074468
-
(2007)
Blood
, vol.110
, pp. 1906-1915
-
-
Bryceson, Y.T.1
Rudd, E.2
Zheng, C.3
Edner, J.4
Ma, D.5
Wood, S.M.6
-
74
-
-
37549041674
-
Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line
-
doi:10.1016/j.bbrc.2007.11.079
-
Marcet-Palacios M, Odemuyiwa SO, Coughlin JJ, Garofoli D, Ewen C, Davidson CE, et al. Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. Biochem Biophys Res Commun (2008) 366:617-23. doi:10.1016/j.bbrc.2007.11.079
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 617-623
-
-
Marcet-Palacios, M.1
Odemuyiwa, S.O.2
Coughlin, J.J.3
Garofoli, D.4
Ewen, C.5
Davidson, C.E.6
-
75
-
-
73249140312
-
A role for endobrevin/VAMP8 in CTL lytic granule exocytosis
-
doi:10.1002/eji.200939378
-
Loo LS, Hwang LA, Ong YM, Tay HS, Wang CC, Hong W. A role for endobrevin/VAMP8 in CTL lytic granule exocytosis. Eur J Immunol (2009) 39:3520-8. doi:10.1002/eji.200939378
-
(2009)
Eur J Immunol
, vol.39
, pp. 3520-3528
-
-
Loo, L.S.1
Hwang, L.A.2
Ong, Y.M.3
Tay, H.S.4
Wang, C.C.5
Hong, W.6
-
76
-
-
80054895698
-
VAMP4-and VAMP7-expressing vesicles are both required for cytotoxic granule exocytosis in NK cells
-
doi:10.1002/eji.201141582
-
Krzewski K, Gil-Krzewska A, Watts J, Stern JN, Strominger JL. VAMP4-and VAMP7-expressing vesicles are both required for cytotoxic granule exocytosis in NK cells. Eur J Immunol (2011) 41:3323-9. doi:10.1002/eji.201141582
-
(2011)
Eur J Immunol
, vol.41
, pp. 3323-3329
-
-
Krzewski, K.1
Gil-Krzewska, A.2
Watts, J.3
Stern, J.N.4
Strominger, J.L.5
-
77
-
-
34247880547
-
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4
-
doi:10.1038/ni1431
-
Ménager MM, Ménasché G, Romao M, Knapnougel P, Ho CH, Garfa M, et al. Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immunol (2007) 8:257-67. doi:10.1038/ni1431
-
(2007)
Nat Immunol
, vol.8
, pp. 257-267
-
-
Ménager, M.M.1
Ménasché, G.2
Romao, M.3
Knapnougel, P.4
Ho, C.H.5
Garfa, M.6
-
78
-
-
70349148575
-
Calcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis
-
doi:10.1111/j.1600-065X.2009.00809.x
-
Pores-Fernando AT, Zweifach A. Calcium influx and signaling in cytotoxic T-lymphocyte lytic granule exocytosis. Immunol Rev (2009) 231:160-73. doi:10.1111/j.1600-065X.2009.00809.x
-
(2009)
Immunol Rev
, vol.231
, pp. 160-173
-
-
Pores-Fernando, A.T.1
Zweifach, A.2
-
79
-
-
29144471909
-
The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells
-
Tassi I, Colonna M. The cytotoxicity receptor CRACC (CS-1) recruits EAT-2 and activates the PI3K and phospholipase Cgamma signaling pathways in human NK cells. J Immunol (2005) 175:7996-8002.
-
(2005)
J Immunol
, vol.175
, pp. 7996-8002
-
-
Tassi, I.1
Colonna, M.2
-
80
-
-
79952771117
-
ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis
-
doi:10.1073/pnas.1013285108
-
Maul-Pavicic A, Chiang SC, Rensing-Ehl A, Jessen B, Fauriat C, Wood SM, et al. ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis. Proc Natl Acad Sci U S A (2011) 108:3324-9. doi:10.1073/pnas.1013285108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3324-3329
-
-
Maul-Pavicic, A.1
Chiang, S.C.2
Rensing-Ehl, A.3
Jessen, B.4
Fauriat, C.5
Wood, S.M.6
-
81
-
-
22144469846
-
Arf6: a new player in FcgammaRIIIA lymphocyte-mediated cytotoxicity
-
doi:10.1182/blood-2004-10-4100
-
Galandrini R, Micucci F, Tassi I, Cifone MG, Cinque B, Piccoli M, et al. Arf6: a new player in FcgammaRIIIA lymphocyte-mediated cytotoxicity. Blood (2005) 106:577-83. doi:10.1182/blood-2004-10-4100
-
(2005)
Blood
, vol.106
, pp. 577-583
-
-
Galandrini, R.1
Micucci, F.2
Tassi, I.3
Cifone, M.G.4
Cinque, B.5
Piccoli, M.6
-
82
-
-
33846498689
-
Expression and function of synaptotagmin VII in CTLs
-
Fowler KT, Andrews NW, Huleatt JW. Expression and function of synaptotagmin VII in CTLs. J Immunol (2007) 178:1498-504.
-
(2007)
J Immunol
, vol.178
, pp. 1498-1504
-
-
Fowler, K.T.1
Andrews, N.W.2
Huleatt, J.W.3
-
83
-
-
84858042087
-
PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway
-
doi:10.1182/blood-2010-12-324160
-
Capuano C, Paolini R, Molfetta R, Frati L, Santoni A, Galandrini R. PIP2-dependent regulation of Munc13-4 endocytic recycling: impact on the cytolytic secretory pathway. Blood (2012) 119:2252-62. doi:10.1182/blood-2010-12-324160
-
(2012)
Blood
, vol.119
, pp. 2252-2262
-
-
Capuano, C.1
Paolini, R.2
Molfetta, R.3
Frati, L.4
Santoni, A.5
Galandrini, R.6
-
84
-
-
68249149660
-
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses
-
doi:10.1016/j.immuni.2009.05.009
-
Liu D, Bryceson YT, Meckel T, Vasiliver-Shamis G, Dustin ML, Long EO. Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses. Immunity (2009) 31:99-109. doi:10.1016/j.immuni.2009.05.009
-
(2009)
Immunity
, vol.31
, pp. 99-109
-
-
Liu, D.1
Bryceson, Y.T.2
Meckel, T.3
Vasiliver-Shamis, G.4
Dustin, M.L.5
Long, E.O.6
-
85
-
-
77956621573
-
Granzyme B is recovered by natural killer cells via clathrin-dependent endocytosis
-
doi:10.1007/s00018-010-0377-8
-
Li P, Zheng G, Yang Y, Zhang C, Xiong P, Xu Y, et al. Granzyme B is recovered by natural killer cells via clathrin-dependent endocytosis. Cell Mol Life Sci (2010) 67:3197-208. doi:10.1007/s00018-010-0377-8
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3197-3208
-
-
Li, P.1
Zheng, G.2
Yang, Y.3
Zhang, C.4
Xiong, P.5
Xu, Y.6
-
86
-
-
48549099675
-
Serial killing of tumor cells by human natural killer cells-enhancement by therapeutic antibodies
-
doi:10.1371/journal.pone.0000326
-
Bhat R, Watzl C. Serial killing of tumor cells by human natural killer cells-enhancement by therapeutic antibodies. PLoS One (2007) 2:e326. doi:10.1371/journal.pone.0000326
-
(2007)
PLoS One
, vol.2
-
-
Bhat, R.1
Watzl, C.2
-
87
-
-
84876236461
-
Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells
-
doi:10.1073/pnas.1221312110
-
Choi PJ, Mitchison TJ. Imaging burst kinetics and spatial coordination during serial killing by single natural killer cells. Proc Natl Acad Sci U S A (2013) 110:6488-93. doi:10.1073/pnas.1221312110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 6488-6493
-
-
Choi, P.J.1
Mitchison, T.J.2
-
88
-
-
84874447340
-
Classification of human natural killer cells based on migration behavior and cytotoxic response
-
doi:10.1182/blood-2012-06-439851
-
Vanherberghen B, Olofsson PE, Forslund E, Sternberg-Simon M, Khorshidi MA, Pacouret S, et al. Classification of human natural killer cells based on migration behavior and cytotoxic response. Blood (2013) 121:1326-34. doi:10.1182/blood-2012-06-439851
-
(2013)
Blood
, vol.121
, pp. 1326-1334
-
-
Vanherberghen, B.1
Olofsson, P.E.2
Forslund, E.3
Sternberg-Simon, M.4
Khorshidi, M.A.5
Pacouret, S.6
-
89
-
-
0028914352
-
Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway
-
doi:10.1002/eji.1830250432
-
Isaaz S, Baetz K, Olsen K, Podack E, Griffiths GM. Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway. Eur J Immunol (1995) 25:1071-9. doi:10.1002/eji.1830250432
-
(1995)
Eur J Immunol
, vol.25
, pp. 1071-1079
-
-
Isaaz, S.1
Baetz, K.2
Olsen, K.3
Podack, E.4
Griffiths, G.M.5
-
90
-
-
4644262299
-
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking
-
doi:10.1038/nature02896
-
Di Paolo G, Moskowitz HS, Gipson K, Wenk MR, Voronov S, Obayashi M, et al. Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking. Nature (2004) 431:415-22. doi:10.1038/nature02896
-
(2004)
Nature
, vol.431
, pp. 415-422
-
-
Di Paolo, G.1
Moskowitz, H.S.2
Gipson, K.3
Wenk, M.R.4
Voronov, S.5
Obayashi, M.6
-
91
-
-
58149198192
-
Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity
-
Arneson LN, Segovis CM, Gomez TS, Schoon RA, Dick CJ, Lou Z, et al. Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity. J Immunol (2008) 181:6995-7001.
-
(2008)
J Immunol
, vol.181
, pp. 6995-7001
-
-
Arneson, L.N.1
Segovis, C.M.2
Gomez, T.S.3
Schoon, R.A.4
Dick, C.J.5
Lou, Z.6
-
92
-
-
79953840956
-
Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance
-
doi:10.1126/scisignal.2001608
-
Guia S, Jaeger BN, Piatek S, Mailfert S, Trombik T, Fenis A, et al. Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci Signal (2011) 4:ra21. doi:10.1126/scisignal.2001608
-
(2011)
Sci Signal
, vol.4
-
-
Guia, S.1
Jaeger, B.N.2
Piatek, S.3
Mailfert, S.4
Trombik, T.5
Fenis, A.6
-
93
-
-
84860007628
-
The adaptor protein Crk controls activation and inhibition of natural killer cells
-
doi:10.1016/j.immuni.2012.03.007
-
Liu D, Peterson ME, Long EO. The adaptor protein Crk controls activation and inhibition of natural killer cells. Immunity (2012) 36:600-11. doi:10.1016/j.immuni.2012.03.007
-
(2012)
Immunity
, vol.36
, pp. 600-611
-
-
Liu, D.1
Peterson, M.E.2
Long, E.O.3
|