A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse

Science Signaling

Volumn 4, Issue 201, 2011, Pages

  Carlin, Leo M ^a,b   Evans, Rachel ^a,b   Milewicz, Hanna ^a   Fernandes, Luis ^b   Matthews, Daniel R ^a,b   Perani, Michela ^a   Levitt, James ^a   Keppler, Melanie D ^a,b   Monypenny, James ^a,b   Coolen, Ton ^a,b   Barber, Paul R ^b,c   Vojnovic, Borivoj ^b,c   Suhling, Klaus ^a   Fraternali, Franca ^b   Ameer Beg, Simon ^a,b   Parker, Peter J ^a,d   Thomas, N Shaun B ^a   Ng, Tony ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE RHOGEF6; GUANINE NUCLEOTIDE RHOGEF7; GUANOSINE TRIPHOSPHATASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN CDC42; PROTEIN KINASE B; RHO RELATED GTPASE FROM PLANTS 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOSENSOR; CATALYSIS; CELL INTERACTION; CELL MEMBRANE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; INNATE IMMUNITY; NATURAL KILLER CELL; POLARIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SYNAPSE;

BIOLOGICAL CLOCKS; CDC42 GTP-BINDING PROTEIN; CELL LINE, TRANSFORMED; CLASS IA PHOSPHATIDYLINOSITOL 3-KINASE; CYTOSKELETON; ENZYME ACTIVATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; IMMUNITY, CELLULAR; IMMUNITY, INNATE; IMMUNOLOGICAL SYNAPSES; KILLER CELLS, NATURAL; NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; TISSUE THERAPY;

EID: 82555196507     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2001729     Document Type: Article

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