-
1
-
-
0029044085
-
The cell biology of CTL killing
-
Griffiths GM. The cell biology of CTL killing. Curr Opin Immunol 1995 7 : 343 348.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 343-348
-
-
Griffiths, G.M.1
-
2
-
-
0028294895
-
The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects
-
Berke G. The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects. Annu Rev Immunol 1994 12 : 735 753.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 735-753
-
-
Berke, G.1
-
3
-
-
0028932731
-
The CTL's kiss of death
-
Berke G. The CTL's kiss of death. Cell 1995 81 : 9 12.
-
(1995)
Cell
, vol.81
, pp. 9-12
-
-
Berke, G.1
-
4
-
-
0031053758
-
Killing mechanisms of cytotoxic lymphocytes
-
Berke G. Killing mechanisms of cytotoxic lymphocytes. Curr Opin Hematol 1997 4 : 32 40.
-
(1997)
Curr Opin Hematol
, vol.4
, pp. 32-40
-
-
Berke, G.1
-
5
-
-
33746067933
-
T-cell receptor signaling events triggering granule exocytosis
-
Radoja S, Frey AB, Vukmanovic S. T-cell receptor signaling events triggering granule exocytosis. Crit Rev Immunol 2006 26 : 265 290.
-
(2006)
Crit Rev Immunol
, vol.26
, pp. 265-290
-
-
Radoja, S.1
Frey, A.B.2
Vukmanovic, S.3
-
6
-
-
0033136784
-
T cell responses to Gram-negative intracellular bacterial pathogens: a role for CD8+ T cells in immunity to Salmonella infection and the involvement of MHC class Ib molecules
-
Lo W-F, Ong H, Metcalf ES, Soloski MJ. T cell responses to Gram-negative intracellular bacterial pathogens: a role for CD8+ T cells in immunity to Salmonella infection and the involvement of MHC class Ib molecules. J Immunol 1999 162 : 5398 5406.
-
(1999)
J Immunol
, vol.162
, pp. 5398-5406
-
-
Lo W-F1
Ong, H.2
Metcalf, E.S.3
Soloski, M.J.4
-
7
-
-
58849123775
-
Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo
-
Woodworth JS, Wu Y, Behar SM. Mycobacterium tuberculosis-specific CD8+ T cells require perforin to kill target cells and provide protection in vivo. J Immunol 2008 181 : 8595 8603.
-
(2008)
J Immunol
, vol.181
, pp. 8595-8603
-
-
Woodworth, J.S.1
Wu, Y.2
Behar, S.M.3
-
8
-
-
0025597939
-
The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments
-
Burkhardt JK, Hester S, Lapham CK, Argon Y. The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments. J Cell Biol 1990 111 : 2327 2340.
-
(1990)
J Cell Biol
, vol.111
, pp. 2327-2340
-
-
Burkhardt, J.K.1
Hester, S.2
Lapham, C.K.3
Argon, Y.4
-
9
-
-
38049136577
-
NK cells at the interface between innate and adaptive immunity
-
Moretta A, Marcenaro E, Parolini S, Ferlazzo G, Moretta L. NK cells at the interface between innate and adaptive immunity. Cell Death Differ 2008 15 : 226 233.
-
(2008)
Cell Death Differ
, vol.15
, pp. 226-233
-
-
Moretta, A.1
Marcenaro, E.2
Parolini, S.3
Ferlazzo, G.4
Moretta, L.5
-
10
-
-
33751540102
-
Activation of primary T lymphocytes results in lysosome development and polarized granule exocytosis in CD4+ and CD8+ subsets, whereas expression of lytic molecules confers cytotoxicity to CD8+ T cells
-
Shen DT, Ma JSY, Mather J, Vukmanovic S, Radoja S. Activation of primary T lymphocytes results in lysosome development and polarized granule exocytosis in CD4+ and CD8+ subsets, whereas expression of lytic molecules confers cytotoxicity to CD8+ T cells. J Leukoc Biol 2006 80 : 827 837.
-
(2006)
J Leukoc Biol
, vol.80
, pp. 827-837
-
-
Shen, D.T.1
Ma, J.S.Y.2
Mather, J.3
Vukmanovic, S.4
Radoja, S.5
-
11
-
-
33746365086
-
The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells
-
Shevach EM, DiPaolo RA, Andersson J, Zhao DM, Stephens GL, Thornton AM. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev 2006 212 : 60 73.
-
(2006)
Immunol Rev
, vol.212
, pp. 60-73
-
-
Shevach, E.M.1
DiPaolo, R.A.2
Andersson, J.3
Zhao, D.M.4
Stephens, G.L.5
Thornton, A.M.6
-
12
-
-
0033520970
-
Perforin gene defects in familial hemophagocytic lymphohistiocytosis
-
Stepp SE, et al. Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science 1999 286 : 1957 1959.
-
(1999)
Science
, vol.286
, pp. 1957-1959
-
-
Stepp, S.E.1
-
13
-
-
42049086504
-
Hemophagocytic lymphohistiocytosis and other hemophagocytic disorders
-
viii.
-
Filipovich AH. Hemophagocytic lymphohistiocytosis and other hemophagocytic disorders. Immunol Allergy Clin North Am 2008 28 : 293 313. viii.
-
(2008)
Immunol Allergy Clin North Am
, vol.28
, pp. 293-313
-
-
Filipovich, A.H.1
-
15
-
-
33746655745
-
Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses
-
Wiedemann A, Depoil D, Faroudi M, Valitutti S. Cytotoxic T lymphocytes kill multiple targets simultaneously via spatiotemporal uncoupling of lytic and stimulatory synapses. Proc Natl Acad Sci USA 2006 103 : 10 985 10 990.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 10985-10990
-
-
Wiedemann, A.1
Depoil, D.2
Faroudi, M.3
Valitutti, S.4
-
16
-
-
0035654722
-
Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing
-
Lyubchenko TA, Wurth GA, Zweifach A. Role of calcium influx in cytotoxic T lymphocyte lytic granule exocytosis during target cell killing. Immunity 2001 15 : 847 859.
-
(2001)
Immunity
, vol.15
, pp. 847-859
-
-
Lyubchenko, T.A.1
Wurth, G.A.2
Zweifach, A.3
-
17
-
-
0022653477
-
Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography
-
Yanelli JR, Sullivan JA, Mandell GL, Engelhard VH. Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography. J Immunol 1986 136 : 377 382.
-
(1986)
J Immunol
, vol.136
, pp. 377-382
-
-
Yanelli, J.R.1
Sullivan, J.A.2
Mandell, G.L.3
Engelhard, V.H.4
-
18
-
-
0024496197
-
The requirements for triggering of lysis by cytolytic T lymphocyte clones. II. Cyclosporin A inhibits TCR-mediated exocytosis by only selectively inhibits TCR-mediated lytic activity by cloned CTL
-
Lancki DW, Kaper BP, Fitch FW. The requirements for triggering of lysis by cytolytic T lymphocyte clones. II. Cyclosporin A inhibits TCR-mediated exocytosis by only selectively inhibits TCR-mediated lytic activity by cloned CTL. J Immunol 1989 142 : 416 424.
-
(1989)
J Immunol
, vol.142
, pp. 416-424
-
-
Lancki, D.W.1
Kaper, B.P.2
Fitch, F.W.3
-
19
-
-
0027263299
-
A role for calcineurin in degranulation of murine cytotoxic T lymphocytes
-
Dutz JP, Fruman DA, Burakoff SJ, Bierer BE. A role for calcineurin in degranulation of murine cytotoxic T lymphocytes. J Immunol 1993 150 : 2591 2598.
-
(1993)
J Immunol
, vol.150
, pp. 2591-2598
-
-
Dutz, J.P.1
Fruman, D.A.2
Burakoff, S.J.3
Bierer, B.E.4
-
20
-
-
0028288927
-
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
-
Chan AC, Desai DM, Weiss A. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Annu Rev Immunol 1994 12 : 555 592.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 555-592
-
-
Chan, A.C.1
Desai, D.M.2
Weiss, A.3
-
21
-
-
0034093737
-
Signal transduction by the TCR for antigen
-
Kane LP, Lin J, Weiss A. Signal transduction by the TCR for antigen. Curr Opin Immunol 2000 12 : 242 249.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 242-249
-
-
Kane, L.P.1
Lin, J.2
Weiss, A.3
-
23
-
-
0141483523
-
Transcriptional regulation by calcium, calcineurin, and NFAT
-
Hogan PG, Chen L, Nardone J, Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes Dev 2003 17 : 2205 2232.
-
(2003)
Genes Dev
, vol.17
, pp. 2205-2232
-
-
Hogan, P.G.1
Chen, L.2
Nardone, J.3
Rao, A.4
-
24
-
-
0028014460
-
Signal transduction by lymphocyte antigen receptors
-
Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Immunity 1994 76 : 263 274.
-
(1994)
Immunity
, vol.76
, pp. 263-274
-
-
Weiss, A.1
Littman, D.R.2
-
25
-
-
0035064074
-
Calcium signaling mechanisms in T lymphocytes
-
Lewis RS. Calcium signaling mechanisms in T lymphocytes. Annu Rev Immunol 2001 19 : 497 521.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 497-521
-
-
Lewis, R.S.1
-
26
-
-
34548233165
-
Calcium signalling in lymphocyte activation and disease
-
Feske S. Calcium signalling in lymphocyte activation and disease. Nat Rev Immunol 2007 7 : 690 702.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 690-702
-
-
Feske, S.1
-
27
-
-
45449093954
-
Calcium signaling in lymphocytes
-
Oh-hora M, Rao A. Calcium signaling in lymphocytes. Curr Opin Immunol 2008 20 : 250 258.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 250-258
-
-
Oh-hora, M.1
Rao, A.2
-
28
-
-
57849148942
-
Calcium signaling in immune cells
-
Vig M, Kinet JP. Calcium signaling in immune cells. Nat Immun 2009 10 : 21 27.
-
(2009)
Nat Immun
, vol.10
, pp. 21-27
-
-
Vig, M.1
Kinet, J.P.2
-
30
-
-
0022575011
-
A model for receptor-regulated calcium entry
-
Putney JW Jr. A model for receptor-regulated calcium entry. Cell Calcium 1986 7 : 1 12.
-
(1986)
Cell Calcium
, vol.7
, pp. 1-12
-
-
Putney Jr., J.W.1
-
32
-
-
0028589615
-
A calcium current activated by store depletion in human lymphocytes is absent in a primary immuno-deficiency
-
Partiseti M, Le Deist F, Hivroz C, Fischer A, Korn H, Choquet D. A calcium current activated by store depletion in human lymphocytes is absent in a primary immuno-deficiency. J Biol Chem 1994 269 : 32 327 32 335.
-
(1994)
J Biol Chem
, vol.269
, pp. 32327-32335
-
-
Partiseti, M.1
Le Deist, F.2
Hivroz, C.3
Fischer, A.4
Korn, H.5
Choquet, D.6
-
33
-
-
33646576875
-
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
-
Feske S, et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 2006 441 : 179 185.
-
(2006)
Nature
, vol.441
, pp. 179-185
-
-
Feske, S.1
-
34
-
-
33748669602
-
Orai1 is an essential pore subunit of the CRAC channel
-
Prakriya M, Feske S, Gwack Y, Srikanth S, Rao A, Hogan PG. Orai1 is an essential pore subunit of the CRAC channel. Nature 2006 443 : 230 233.
-
(2006)
Nature
, vol.443
, pp. 230-233
-
-
Prakriya, M.1
Feske, S.2
Gwack, Y.3
Srikanth, S.4
Rao, A.5
Hogan, P.G.6
-
35
-
-
61349137530
-
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
-
Park CY, et al. STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 2009 136 : 876 890.
-
(2009)
Cell
, vol.136
, pp. 876-890
-
-
Park, C.Y.1
-
36
-
-
1842631103
-
Jurkat T cells and development of the T-cell receptor signalling paradigm
-
Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat Rev Immunol 2004 4 : 301 308.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 301-308
-
-
Abraham, R.T.1
Weiss, A.2
-
37
-
-
52649128664
-
Shouts, whispers and the kiss of death: directional secretion in T cells
-
Huse M, Quann EJ, Davis MM. Shouts, whispers and the kiss of death: directional secretion in T cells. Nat Immun 2008 9 : 1105 1111.
-
(2008)
Nat Immun
, vol.9
, pp. 1105-1111
-
-
Huse, M.1
Quann, E.J.2
Davis, M.M.3
-
38
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
Monks CR, Freiberg BA, Kupfer H, Sciaky N, Kupfer A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 1998 395 : 82 86.
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.R.1
Freiberg, B.A.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
39
-
-
0035655587
-
The immunological synapse of CTL contains a secretory domain and membrane bridges
-
Stinchcombe JC, Bossi G, Booth S, Griffiths GM. The immunological synapse of CTL contains a secretory domain and membrane bridges. Immunity 2001 15 : 751 761.
-
(2001)
Immunity
, vol.15
, pp. 751-761
-
-
Stinchcombe, J.C.1
Bossi, G.2
Booth, S.3
Griffiths, G.M.4
-
40
-
-
0035940426
-
Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells
-
Potter TA, Grebe K, Freiberg B, Kupfer A. Formation of supramolecular activation clusters on fresh ex vivo CD8+ T cells after engagement of the T cell antigen receptor and CD8 by antigen-presenting cells. Proc Natl Acad Sci USA 2001 98 : 12 624 12 629.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12624-12629
-
-
Potter, T.A.1
Grebe, K.2
Freiberg, B.3
Kupfer, A.4
-
41
-
-
0021714772
-
Reorientation of the microtubule-organizing center and the golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells
-
Kupfer A, Dennert G. Reorientation of the microtubule-organizing center and the golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells. J Immunol 1984 133 : 2762 2766.
-
(1984)
J Immunol
, vol.133
, pp. 2762-2766
-
-
Kupfer, A.1
Dennert, G.2
-
42
-
-
33749185296
-
Centrosome polarization delivers secretory granules to the immunological synapse
-
Stinchcombe JC, Majorovits E, Bossi G, Fuller S, Griffiths GM. Centrosome polarization delivers secretory granules to the immunological synapse. Nature 2006 443 : 462 465.
-
(2006)
Nature
, vol.443
, pp. 462-465
-
-
Stinchcombe, J.C.1
Majorovits, E.2
Bossi, G.3
Fuller, S.4
Griffiths, G.M.5
-
43
-
-
0000572782
-
The specific direct interaction of helper T cells and antigen-presenting B cells
-
Kupfer A, Swain SL, Janeway CA, Singer SJ. The specific direct interaction of helper T cells and antigen-presenting B cells. Proc Natl Acad Sci USA 1986 83 : 6080 6083.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 6080-6083
-
-
Kupfer, A.1
Swain, S.L.2
Janeway, C.A.3
Singer, S.J.4
-
44
-
-
0025978984
-
Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells
-
Kupfer A, Mosmann TR, Kupfer H. Polarized expression of cytokines in cell conjugates of helper T cells and splenic B cells. Proc Natl Acad Sci USA 1991 88 : 775 779.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 775-779
-
-
Kupfer, A.1
Mosmann, T.R.2
Kupfer, H.3
-
45
-
-
0028354216
-
Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions
-
Kupfer H, Monks CR, Kupfer A. Small splenic B cells that bind to antigen-specific T helper (Th) cells and face the site of cytokine production in the Th cells selectively proliferate: immunofluorescence microscopic studies of Th-B antigen-presenting cell interactions. J Exp Med 1994 179 : 1507 1515.
-
(1994)
J Exp Med
, vol.179
, pp. 1507-1515
-
-
Kupfer, H.1
Monks, C.R.2
Kupfer, A.3
-
46
-
-
0038445896
-
Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization
-
Kuhne MR, et al. Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization. J Immunol 2003 171 : 860 866.
-
(2003)
J Immunol
, vol.171
, pp. 860-866
-
-
Kuhne, M.R.1
-
47
-
-
0344006229
-
Polarizaton of the golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets
-
Kupfer A, Dennert G, Singer SJ. Polarizaton of the golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets. Proc Natl Acad Sci USA 1983 80 : 7224 7228.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 7224-7228
-
-
Kupfer, A.1
Dennert, G.2
Singer, S.J.3
-
48
-
-
0034330547
-
Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells
-
Jiang K, et al. Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells. Nat Immun 2000 1 : 419 425.
-
(2000)
Nat Immun
, vol.1
, pp. 419-425
-
-
Jiang, K.1
-
49
-
-
0036863736
-
The secretory synapse: the secrets of a serial killer
-
Bossi G, Trambas C, Booth S, Clark R, Stinchcombe J, Griffiths GM. The secretory synapse: the secrets of a serial killer. Immunol Rev 2002 189 : 152 160.
-
(2002)
Immunol Rev
, vol.189
, pp. 152-160
-
-
Bossi, G.1
Trambas, C.2
Booth, S.3
Clark, R.4
Stinchcombe, J.5
Griffiths, G.M.6
-
50
-
-
0024327897
-
Cell biology of cytotoxic and helper T cell functions
-
Kupfer S. Cell biology of cytotoxic and helper T cell functions. Ann Rev Immunol 1989 7 : 309 337.
-
(1989)
Ann Rev Immunol
, vol.7
, pp. 309-337
-
-
Kupfer, S.1
-
51
-
-
0025905925
-
Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
-
Peters P, et al. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J Exp Med 1991 173 : 1099 1109.
-
(1991)
J Exp Med
, vol.173
, pp. 1099-1109
-
-
Peters, P.1
-
54
-
-
3042793578
-
Linking albinism and immunity: the secrets of secretory lysosomes
-
Stinchcombe J, Bossi G, Griffiths GM. Linking albinism and immunity: the secrets of secretory lysosomes. Science 2004 305 : 55 59.
-
(2004)
Science
, vol.305
, pp. 55-59
-
-
Stinchcombe, J.1
Bossi, G.2
Griffiths, G.M.3
-
56
-
-
0022497854
-
Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity
-
Young JD, Hengartner H, Podack ER, Cohn ZA. Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell 1986 44 : 849 859.
-
(1986)
Cell
, vol.44
, pp. 849-859
-
-
Young, J.D.1
Hengartner, H.2
Podack, E.R.3
Cohn, Z.A.4
-
57
-
-
34247577498
-
Delivering the kiss of death: progress on understanding how perforin works
-
Pipkin ME, Lieberman J. Delivering the kiss of death: progress on understanding how perforin works. Curr Opin Immunol 2007 19 : 301 308.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 301-308
-
-
Pipkin, M.E.1
Lieberman, J.2
-
58
-
-
0037136311
-
Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation
-
Balaji KN, Schaschke N, Machleidt W, Catalfamo M, Henkart PA. Surface cathepsin B protects cytotoxic lymphocytes from self-destruction after degranulation. J Exp Med 2002 196 : 493 503.
-
(2002)
J Exp Med
, vol.196
, pp. 493-503
-
-
Balaji, K.N.1
Schaschke, N.2
Machleidt, W.3
Catalfamo, M.4
Henkart, P.A.5
-
59
-
-
55549138390
-
Serpins in T cell immunity
-
Bots M, Medema JP. Serpins in T cell immunity. J Leukoc Biol 2008 84 : 1238 1247.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 1238-1247
-
-
Bots, M.1
Medema, J.P.2
-
60
-
-
0037438474
-
The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency
-
Hirst CE, et al. The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency. J Immunol 2003 170 : 805 815.
-
(2003)
J Immunol
, vol.170
, pp. 805-815
-
-
Hirst, C.E.1
-
62
-
-
0027175221
-
CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help
-
Harding FA, Allison JP. CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help. J Exp Med 1993 177 : 1791 1796.
-
(1993)
J Exp Med
, vol.177
, pp. 1791-1796
-
-
Harding, F.A.1
Allison, J.P.2
-
63
-
-
0032530696
-
Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes
-
Berg NN, Puente LG, Dawicki W, Ostergaard HL. Sustained TCR signaling is required for mitogen-activated protein kinase activation and degranulation by cytotoxic T lymphocytes. J Immunol 1998 161 : 2919 2924.
-
(1998)
J Immunol
, vol.161
, pp. 2919-2924
-
-
Berg, N.N.1
Puente, L.G.2
Dawicki, W.3
Ostergaard, H.L.4
-
64
-
-
61849128182
-
T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
-
Salmond RJ, Filby A, Qureshi I, Caserta S, Zamoyska R. T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance. Immunol Rev 2009 228 : 9 22.
-
(2009)
Immunol Rev
, vol.228
, pp. 9-22
-
-
Salmond, R.J.1
Filby, A.2
Qureshi, I.3
Caserta, S.4
Zamoyska, R.5
-
65
-
-
0037108305
-
Engagement of the inhibitory receptor CD158a interrupts TCR signaling, preventing dynamic membrane reorganization in CTL/tumor cell interaction
-
Guerra N, et al. Engagement of the inhibitory receptor CD158a interrupts TCR signaling, preventing dynamic membrane reorganization in CTL/tumor cell interaction. Blood 2002 100 : 2874 2881.
-
(2002)
Blood
, vol.100
, pp. 2874-2881
-
-
Guerra, N.1
-
66
-
-
0141447817
-
T-cell receptor signal transmission: who gives an ITAM?
-
Pitcher LA, van Oers NSC. T-cell receptor signal transmission: who gives an ITAM? Trends Immunol 2003 24 : 554 560.
-
(2003)
Trends Immunol
, vol.24
, pp. 554-560
-
-
Pitcher, L.A.1
Van Oers, N.S.C.2
-
67
-
-
0026095639
-
Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-g1
-
Weiss A, Koretzky G, Schatzman RC, Kadlecek T. Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-g1. Proc Natl Acad Sci USA 1991 88 : 5484 5488.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 5484-5488
-
-
Weiss, A.1
Koretzky, G.2
Schatzman, R.C.3
Kadlecek, T.4
-
68
-
-
0037337159
-
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
-
Newton AC. Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm. Biochem J 2003 370 : 361 371.
-
(2003)
Biochem J
, vol.370
, pp. 361-371
-
-
Newton, A.C.1
-
69
-
-
0242321186
-
Divergence and complexities in DAG signaling: looking beyond PKC
-
Yang C, Kazanietz MG. Divergence and complexities in DAG signaling: looking beyond PKC. Trends Pharmacol Sci 2003 24 : 602 608.
-
(2003)
Trends Pharmacol Sci
, vol.24
, pp. 602-608
-
-
Yang, C.1
Kazanietz, M.G.2
-
70
-
-
0037092038
-
Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C
-
Villalba M, et al. Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C. J Cell Biol 2002 157 : 253 263.
-
(2002)
J Cell Biol
, vol.157
, pp. 253-263
-
-
Villalba, M.1
-
71
-
-
0037902559
-
Protein kinase C-theta (PKCtheta): it's all about location, location, location
-
Altman A, Villalba M. Protein kinase C-theta (PKCtheta): it's all about location, location, location. Immunol Rev 2003 192 : 53 63.
-
(2003)
Immunol Rev
, vol.192
, pp. 53-63
-
-
Altman, A.1
Villalba, M.2
-
72
-
-
0036952044
-
Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death
-
Altman A, Villalba M. Protein kinase C-theta (PKC theta): a key enzyme in T cell life and death. J Biochem 2002 132 : 841 846.
-
(2002)
J Biochem
, vol.132
, pp. 841-846
-
-
Altman, A.1
Villalba, M.2
-
73
-
-
0021917674
-
Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores
-
Imboden JB, Stobo JD. Transmembrane signalling by the T cell antigen receptor. Perturbation of the T3-antigen receptor complex generates inositol phosphates and releases calcium ions from intracellular stores. J Exp Med 1985 161 : 446 456.
-
(1985)
J Exp Med
, vol.161
, pp. 446-456
-
-
Imboden, J.B.1
Stobo, J.D.2
-
74
-
-
17044412522
-
Phosphatidylinositol-3-kinase regulates PKCθ activity in cytotoxic T cells
-
Puente LG, Mireau LR, Lysechko TL, Ostergaard HL. Phosphatidylinositol-3- kinase regulates PKCθ activity in cytotoxic T cells. Mol Immunol 2005 42 : 1177 1184.
-
(2005)
Mol Immunol
, vol.42
, pp. 1177-1184
-
-
Puente, L.G.1
Mireau, L.R.2
Lysechko, T.L.3
Ostergaard, H.L.4
-
75
-
-
29144503720
-
A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation
-
Robertson L, Mireau L, Ostergaard H. A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation. J Immunol 2005 175 : 8138 8145.
-
(2005)
J Immunol
, vol.175
, pp. 8138-8145
-
-
Robertson, L.1
Mireau, L.2
Ostergaard, H.3
-
76
-
-
2942593739
-
2+) influx does not underlie the role of extracellular signal-regulated kinases in cytotoxic T lymphocyte lytic granule exocytosis
-
2+) influx does not underlie the role of extracellular signal-regulated kinases in cytotoxic T lymphocyte lytic granule exocytosis. J Biol Chem 2004 279 : 25 646 25 652.
-
(2004)
J Biol Chem
, vol.279
, pp. 25646-25652
-
-
Fierro, A.F.1
Wurth, G.A.2
Zweifach, A.3
-
77
-
-
33645924074
-
A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: plasticity in PKC regulation of ERK
-
Puente LG, He JS, Ostergaard HL. A novel PKC regulates ERK activation and degranulation of cytotoxic T lymphocytes: plasticity in PKC regulation of ERK. Eur J Immunol 2006 36 : 1009 1018.
-
(2006)
Eur J Immunol
, vol.36
, pp. 1009-1018
-
-
Puente, L.G.1
He, J.S.2
Ostergaard, H.L.3
-
78
-
-
0034671815
-
Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins
-
Puente LG, Stone JC, Ostergaard HL. Evidence for protein kinase C-dependent and -independent activation of mitogen-activated protein kinase in T cells: potential role of additional diacylglycerol binding proteins. J Immunol 2000 165 : 6865 6871.
-
(2000)
J Immunol
, vol.165
, pp. 6865-6871
-
-
Puente, L.G.1
Stone, J.C.2
Ostergaard, H.L.3
-
79
-
-
44149101935
-
ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis
-
Pores-Fernando AT, Gaur S, Grybko MJ, Zweifach A. ERK activation is only one role of PKC in TCR-independent cytotoxic T cell granule exocytosis. Biochem Biophys Res Commun 2008 371 : 630 634.
-
(2008)
Biochem Biophys Res Commun
, vol.371
, pp. 630-634
-
-
Pores-Fernando, A.T.1
Gaur, S.2
Grybko, M.J.3
Zweifach, A.4
-
80
-
-
0034086261
-
Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation
-
Villalba M, Hernandez J, Deckert M, Tanaka Y, Altman A. Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation. Eur J Immunol 2000 30 : 1587 1596.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1587-1596
-
-
Villalba, M.1
Hernandez, J.2
Deckert, M.3
Tanaka, Y.4
Altman, A.5
-
81
-
-
0033666324
-
Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential
-
Gunzer M, et al. Antigen presentation in extracellular matrix: interactions of T cells with dendritic cells are dynamic, short lived, and sequential. Immunity 2000 13 : 323 332.
-
(2000)
Immunity
, vol.13
, pp. 323-332
-
-
Gunzer, M.1
-
82
-
-
0032545218
-
A receptor/cytoskeletal movement triggered by costimulation during T cell activation
-
Wulfing C, Davis MM. A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science 1998 282 : 2266 2269.
-
(1998)
Science
, vol.282
, pp. 2266-2269
-
-
Wulfing, C.1
Davis, M.M.2
-
83
-
-
0346147030
-
Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression
-
Pardo J, et al. Differential implication of protein kinase C isoforms in cytotoxic T lymphocyte degranulation and TCR-induced Fas ligand expression. Int Immunol 2003 15 : 1441 1450.
-
(2003)
Int Immunol
, vol.15
, pp. 1441-1450
-
-
Pardo, J.1
-
84
-
-
33846665903
-
Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role
-
Grybko MJ, Pores-Fernando AT, Wurth GA, Zweifach A. Protein kinase C activity is required for cytotoxic T cell lytic granule exocytosis, but the theta isoform does not play a preferential role. J Leukoc Biol 2007 81 : 509 519.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 509-519
-
-
Grybko, M.J.1
Pores-Fernando, A.T.2
Wurth, G.A.3
Zweifach, A.4
-
85
-
-
0023266351
-
The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells
-
Kupfer A, Swain SL, Singer SJ. The specific direct interaction of helper T cells and antigen-presenting B cells. II. Reorientation of the microtubule organizing center and reorganization of the membrane-associated cytoskeleton inside the bound helper T cells. J Exp Med 1987 165 : 1565 1580.
-
(1987)
J Exp Med
, vol.165
, pp. 1565-1580
-
-
Kupfer, A.1
Swain, S.L.2
Singer, S.J.3
-
86
-
-
33344458030
-
T cells use two directionally distinct pathways for cytokine secretion
-
Huse M, Lillemeier BF, Kuhns MS, Chen DS, Davis MM. T cells use two directionally distinct pathways for cytokine secretion. Nat Immun 2006 7 : 247 255.
-
(2006)
Nat Immun
, vol.7
, pp. 247-255
-
-
Huse, M.1
Lillemeier, B.F.2
Kuhns, M.S.3
Chen, D.S.4
Davis, M.M.5
-
87
-
-
0020316410
-
Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound
-
Kupfer A, Louvard D, Singer SJ. Polarization of the Golgi apparatus and the microtubule-organizing center in cultured fibroblasts at the edge of an experimental wound. Proc Natl Acad Sci USA 1982 79 : 2603 2607.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 2603-2607
-
-
Kupfer, A.1
Louvard, D.2
Singer, S.J.3
-
88
-
-
0022854872
-
The directed migration of eukaryotic cells
-
Singer SJ, Kupfer A. The directed migration of eukaryotic cells. Annu Rev Cell Biol 1986 2 : 337 365.
-
(1986)
Annu Rev Cell Biol
, vol.2
, pp. 337-365
-
-
Singer, S.J.1
Kupfer, A.2
-
89
-
-
0017658902
-
Structural analysis of human neutrophil migration. Centriole, microtubule, and microfilament orientation and function during chemotaxis
-
Malech HL, Root RK, Gallin JI. Structural analysis of human neutrophil migration. Centriole, microtubule, and microfilament orientation and function during chemotaxis. J Cell Biol 1977 75 : 666 693.
-
(1977)
J Cell Biol
, vol.75
, pp. 666-693
-
-
Malech, H.L.1
Root, R.K.2
Gallin, J.I.3
-
90
-
-
0020955119
-
Microtubule-organizing centers and cell migration: effect of inhibition of migration and microtubule disruption in endothelial cells
-
Gotlieb AI, Subrahmanyan L, Kalnins VI. Microtubule-organizing centers and cell migration: effect of inhibition of migration and microtubule disruption in endothelial cells. J Cell Biol 1983 96 : 1266 1272.
-
(1983)
J Cell Biol
, vol.96
, pp. 1266-1272
-
-
Gotlieb, A.I.1
Subrahmanyan, L.2
Kalnins, V.I.3
-
91
-
-
0021331350
-
Location of actin, myosin, and microtubular structures during directed locomotion of Dictyostelium amebae
-
Rubino S, Fighetti M, Unger E, Cappuccinelli P. Location of actin, myosin, and microtubular structures during directed locomotion of Dictyostelium amebae. J Cell Biol 1984 98 : 382 390.
-
(1984)
J Cell Biol
, vol.98
, pp. 382-390
-
-
Rubino, S.1
Fighetti, M.2
Unger, E.3
Cappuccinelli, P.4
-
92
-
-
0035797905
-
Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization
-
Palazzo AF, et al. Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization. Curr Biol 2001 11 : 1536 1541.
-
(2001)
Curr Biol
, vol.11
, pp. 1536-1541
-
-
Palazzo, A.F.1
-
93
-
-
0036864649
-
Regulation of microtubule-organizing center orientation and actomyosin cytoskeleton rearrangement during immune interactions
-
Sancho D, et al. Regulation of microtubule-organizing center orientation and actomyosin cytoskeleton rearrangement during immune interactions. Immunol Rev 2002 189 : 84 97.
-
(2002)
Immunol Rev
, vol.189
, pp. 84-97
-
-
Sancho, D.1
-
94
-
-
33749533276
-
Recruitment of dynein to the Jurkat immunological synapse
-
Combs J, et al. Recruitment of dynein to the Jurkat immunological synapse. Proc Natl Acad Sci USA 2006 103 : 14 883 14 888.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14883-14888
-
-
Combs, J.1
-
95
-
-
0031785762
-
Prevention of antigen-induced microtubule organizing center reorientation in cytotoxic T cells by modulation of protein kinase C activity
-
Nesić D, Henderson S, Vukmanović S. Prevention of antigen-induced microtubule organizing center reorientation in cytotoxic T cells by modulation of protein kinase C activity. Int Immunol 1998 10 : 1741 1746.
-
(1998)
Int Immunol
, vol.10
, pp. 1741-1746
-
-
Nesić, D.1
Henderson, S.2
Vukmanović, S.3
-
96
-
-
58149300245
-
Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity
-
Ma JS, Haydar TF, Radoja S. Protein kinase C delta localizes to secretory lysosomes in CD8+ CTL and directly mediates TCR signals leading to granule exocytosis-mediated cytotoxicity. J Immunol 2008 181 : 4716 4722.
-
(2008)
J Immunol
, vol.181
, pp. 4716-4722
-
-
Ma, J.S.1
Haydar, T.F.2
Radoja, S.3
-
97
-
-
34250156284
-
Protein kinase Cdelta regulates antigen receptor-induced lytic granule polarization in mouse CD8+ CTL
-
Ma JS, et al. Protein kinase Cdelta regulates antigen receptor-induced lytic granule polarization in mouse CD8+ CTL. J Immunol 2007 178 : 7814 7821.
-
(2007)
J Immunol
, vol.178
, pp. 7814-7821
-
-
Ma, J.S.1
-
98
-
-
0023228957
-
Requirements for triggering of lysis by cytolytic T lymphocyte clones
-
Lancki DW, Weiss A, Fitch FW. Requirements for triggering of lysis by cytolytic T lymphocyte clones. J Immunol 1987 138 : 3646 3653.
-
(1987)
J Immunol
, vol.138
, pp. 3646-3653
-
-
Lancki, D.W.1
Weiss, A.2
Fitch, F.W.3
-
99
-
-
0023607302
-
Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes
-
Takayama H, Sitkovsky M. Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes. J Exp Med 1987 166 : 725 743.
-
(1987)
J Exp Med
, vol.166
, pp. 725-743
-
-
Takayama, H.1
Sitkovsky, M.2
-
100
-
-
0023820248
-
Mechanistic, functional and immunopharmacological implications of biochemical studies of antigen receptor-triggered cytolytic T-lymphocyte activation
-
Sitkovsky MV. Mechanistic, functional and immunopharmacological implications of biochemical studies of antigen receptor-triggered cytolytic T-lymphocyte activation. Immunol Rev 1988 103 : 127 160.
-
(1988)
Immunol Rev
, vol.103
, pp. 127-160
-
-
Sitkovsky, M.V.1
-
102
-
-
0023265017
-
Protein kinase C required for cytotoxic T lymphocyte triggering
-
Nishimura T, Burakoff SJ, Herrmann SH. Protein kinase C required for cytotoxic T lymphocyte triggering. J Immunol 1987 139 : 2888 2891.
-
(1987)
J Immunol
, vol.139
, pp. 2888-2891
-
-
Nishimura, T.1
Burakoff, S.J.2
Herrmann, S.H.3
-
104
-
-
0032489682
-
Calcium signaling modulates cytolytic T lymphocyte effector functions
-
Esser MT, Haverstick DM, Fuller CL, Gullo CA, Bracale VL. Calcium signaling modulates cytolytic T lymphocyte effector functions. J Exp Med 1998 187 : 1057 1067.
-
(1998)
J Exp Med
, vol.187
, pp. 1057-1067
-
-
Esser, M.T.1
Haverstick, D.M.2
Fuller, C.L.3
Gullo, C.A.4
Bracale, V.L.5
-
105
-
-
0037444474
-
The actin cytoskeleton and cytotoxic T lymphocytes: evidence for multiple roles that could affect granule exocytosis-dependent target cell killing
-
Lyubchenko TA, Wurth GA, Zweifach A. The actin cytoskeleton and cytotoxic T lymphocytes: evidence for multiple roles that could affect granule exocytosis-dependent target cell killing. J Physiol (Lond) 2003 547 : 835 847.
-
(2003)
J Physiol (Lond)
, vol.547
, pp. 835-847
-
-
Lyubchenko, T.A.1
Wurth, G.A.2
Zweifach, A.3
-
106
-
-
0024208188
-
Function of granule perform and esterases in T cell-mediated reactions
-
Podack ER, Lowrey DM, Lichtenheld M, Hameed A. Function of granule perform and esterases in T cell-mediated reactions. Ann NY Acad Sci 1988 532 : 292 302.
-
(1988)
Ann NY Acad Sci
, vol.532
, pp. 292-302
-
-
Podack, E.R.1
Lowrey, D.M.2
Lichtenheld, M.3
Hameed, A.4
-
107
-
-
0028940744
-
Execution and suicide: cytotoxic lymphocytes enforce draconian laws through seperate molecular pathways
-
Podack ER. Execution and suicide: cytotoxic lymphocytes enforce draconian laws through seperate molecular pathways. Curr Opin Immunol 1995 7 : 11 16.
-
(1995)
Curr Opin Immunol
, vol.7
, pp. 11-16
-
-
Podack, E.R.1
-
108
-
-
0016597777
-
Isolation and characterization of individual functionally reactive cytotoxic T lymphocytes: conjugation, killing and recycling at the single cell level
-
Zagury D, Bernard J, Thierness N, Feldman M, Berke G. Isolation and characterization of individual functionally reactive cytotoxic T lymphocytes: conjugation, killing and recycling at the single cell level. Eur J Immunol 1975 5 : 818 822.
-
(1975)
Eur J Immunol
, vol.5
, pp. 818-822
-
-
Zagury, D.1
Bernard, J.2
Thierness, N.3
Feldman, M.4
Berke, G.5
-
109
-
-
0021895138
-
2+indicators with greatly improved fluorescence properties
-
2+indicators with greatly improved fluorescence properties. J Biol Chem 1985 260 : 3440 3450.
-
(1985)
J Biol Chem
, vol.260
, pp. 3440-3450
-
-
Grynkiewicz, G.1
Poenie, M.2
Tsien, R.Y.3
-
110
-
-
0021998316
-
2+in individual small cells using fluorescence microscopy with dual excitation wavelengths
-
2+in individual small cells using fluorescence microscopy with dual excitation wavelengths. Cell Calcium 1985 6 : 145 157.
-
(1985)
Cell Calcium
, vol.6
, pp. 145-157
-
-
Tsien, R.Y.1
Rink, T.J.2
Poenie, M.3
-
111
-
-
0023205407
-
Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding
-
Gray LS, Gnarra JR, Engelhard VH. Demonstration of a calcium influx in cytolytic T lymphocytes in response to target cell binding. J Immunol 1987 138 : 63 69.
-
(1987)
J Immunol
, vol.138
, pp. 63-69
-
-
Gray, L.S.1
Gnarra, J.R.2
Engelhard, V.H.3
-
112
-
-
0023753446
-
Spatial and temporal characterstics of the increase in intracellular calcium induced in cytotoxic T lymphocytes by cellular antigen
-
Gray LS, Gnarra JR, Sullivan JA, Mandell GL, Engelhard VH. Spatial and temporal characterstics of the increase in intracellular calcium induced in cytotoxic T lymphocytes by cellular antigen. J Immunol 1988 141 : 2424 2430.
-
(1988)
J Immunol
, vol.141
, pp. 2424-2430
-
-
Gray, L.S.1
Gnarra, J.R.2
Sullivan, J.A.3
Mandell, G.L.4
Engelhard, V.H.5
-
113
-
-
0027159139
-
Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx
-
Hess SD, Oortgiesen M, Cahalan MD. Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx. J Immunol 1993 150 : 2620 2633.
-
(1993)
J Immunol
, vol.150
, pp. 2620-2633
-
-
Hess, S.D.1
Oortgiesen, M.2
Cahalan, M.D.3
-
114
-
-
0023212550
-
Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity
-
Treves S, Di Virgilio F, Cerundolo V, Zanovello P, Collavo D, Pozzan T. Calcium and inositolphosphates in the activation of T cell-mediated cytotoxicity. J Exp Med 1987 166 : 33 42.
-
(1987)
J Exp Med
, vol.166
, pp. 33-42
-
-
Treves, S.1
Di Virgilio, F.2
Cerundolo, V.3
Zanovello, P.4
Collavo, D.5
Pozzan, T.6
-
115
-
-
0023510089
-
A calcium- and perforin-independent pathway of killing mediated by murine cytolytic lymphocytes
-
Young JD, Clark WR, Liu CC, Cohn ZA. A calcium- and perforin-independent pathway of killing mediated by murine cytolytic lymphocytes. J Exp Med 1987 166 : 1894 1899.
-
(1987)
J Exp Med
, vol.166
, pp. 1894-1899
-
-
Young, J.D.1
Clark, W.R.2
Liu, C.C.3
Cohn, Z.A.4
-
117
-
-
0028110345
-
Immune function in mice lacking the perforin gene
-
Walsh CM, et al. Immune function in mice lacking the perforin gene. Proc Natl Acad Sci USA 1994 91 : 10854 10858.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10854-10858
-
-
Walsh, C.M.1
-
118
-
-
0023181059
-
The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion
-
Shaw S, Luce GE. The lymphocyte function-associated antigen (LFA)-1 and CD2/LFA-3 pathways of antigen-independent human T cell adhesion. J Immunol 1987 139 : 1037 1045.
-
(1987)
J Immunol
, vol.139
, pp. 1037-1045
-
-
Shaw, S.1
Luce, G.E.2
-
119
-
-
0024415874
-
The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition
-
Makgoba MW, Sanders ME, Shaw S. The CD2-LFA-3 and LFA-1-ICAM pathways: relevance to T-cell recognition. Immunol Today 1989 10 : 417 422.
-
(1989)
Immunol Today
, vol.10
, pp. 417-422
-
-
Makgoba, M.W.1
Sanders, M.E.2
Shaw, S.3
-
120
-
-
0020532081
-
Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes
-
Dennert G, Podack ER. Cytolysis by H-2-specific T killer cells. Assembly of tubular complexes on target membranes. J Exp Med 1983 157 : 1483 1495.
-
(1983)
J Exp Med
, vol.157
, pp. 1483-1495
-
-
Dennert, G.1
Podack, E.R.2
-
121
-
-
0001041396
-
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules
-
Podack ER, Young JD, Cohn ZA. Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules. Proc Natl Acad Sci USA 1985 82 : 8629 8633.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 8629-8633
-
-
Podack, E.R.1
Young, J.D.2
Cohn, Z.A.3
-
122
-
-
0023142138
-
Antigen receptor-triggered secretion of a trypsin-type esterase from cytotoxic T lymphocytes
-
Takayama H, Trenn G, Humphrey W Jr., Bluestone JA, Henkart PA, Sitkovsky MV. Antigen receptor-triggered secretion of a trypsin-type esterase from cytotoxic T lymphocytes. J Immunol 1987 138 : 566 569.
-
(1987)
J Immunol
, vol.138
, pp. 566-569
-
-
Takayama, H.1
Trenn, G.2
Humphrey Jr., W.3
Bluestone, J.A.4
Henkart, P.A.5
Sitkovsky, M.V.6
-
123
-
-
0024381406
-
Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functions
-
Trenn G, Taffs R, Hohman R, Kincaid R, Shevach EM, Sitkovsky M. Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functions. J Immunol 1989 142 : 3796 3802.
-
(1989)
J Immunol
, vol.142
, pp. 3796-3802
-
-
Trenn, G.1
Taffs, R.2
Hohman, R.3
Kincaid, R.4
Shevach, E.M.5
Sitkovsky, M.6
-
124
-
-
0142185336
-
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
-
Betts MR, et al. Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation. J Immunol Methods 2003 281 : 65 78.
-
(2003)
J Immunol Methods
, vol.281
, pp. 65-78
-
-
Betts, M.R.1
-
125
-
-
16644378159
-
Detection of T-cell degranulation: CD107a and b
-
Betts MR, Koup RA. Detection of T-cell degranulation: CD107a and b. Methods Cell Biol 2004 75 : 497 512.
-
(2004)
Methods Cell Biol
, vol.75
, pp. 497-512
-
-
Betts, M.R.1
Koup, R.A.2
-
126
-
-
25844499142
-
Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor
-
Pores-Fernando AT, Bauer RA, Wurth GA, Zweifach A. Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor. J Physiol (Lond) 2005 567 : 891 903.
-
(2005)
J Physiol (Lond)
, vol.567
, pp. 891-903
-
-
Pores-Fernando, A.T.1
Bauer, R.A.2
Wurth, G.A.3
Zweifach, A.4
-
127
-
-
0030982181
-
Mitochondrial regulation of store-operated calcium signaling in T lymphocytes
-
Hoth M, Fanger CM, Lewis RS. Mitochondrial regulation of store-operated calcium signaling in T lymphocytes. J Cell Biol 1997 137 : 633 648.
-
(1997)
J Cell Biol
, vol.137
, pp. 633-648
-
-
Hoth, M.1
Fanger, C.M.2
Lewis, R.S.3
-
128
-
-
34848913375
-
T cell activation requires mitochondrial translocation to the immunological synapse
-
Quintana A, et al. T cell activation requires mitochondrial translocation to the immunological synapse. Proc Natl Acad Sci USA 2007 104 : 14418 14423.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14418-14423
-
-
Quintana, A.1
-
129
-
-
0032580202
-
Calcium oscillations increase the efficiency and specificity of gene expression
-
Dolmetsch RE, Xu K, Lewis RS. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 1998 392 : 933 936.
-
(1998)
Nature
, vol.392
, pp. 933-936
-
-
Dolmetsch, R.E.1
Xu, K.2
Lewis, R.S.3
-
132
-
-
0033522178
-
Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose
-
Guse AH, et al. Regulation of calcium signalling in T lymphocytes by the second messenger cyclic ADP-ribose. Nature 1999 398 : 70 73.
-
(1999)
Nature
, vol.398
, pp. 70-73
-
-
Guse, A.H.1
-
133
-
-
21044439334
-
2+ channel function
-
2+ channel function. J Cell Biol 2005 169 : 435 445.
-
(2005)
J Cell Biol
, vol.169
, pp. 435-445
-
-
Roos, J.1
-
134
-
-
27144515996
-
2+ store to the plasma membrane
-
2+ store to the plasma membrane. Nature 2005 437 : 902 905.
-
(2005)
Nature
, vol.437
, pp. 902-905
-
-
Zhang, S.L.1
-
135
-
-
21844432686
-
2+ influx
-
2+ influx. Curr Biol 2005 15 : 1235 1241.
-
(2005)
Curr Biol
, vol.15
, pp. 1235-1241
-
-
Liou, J.1
-
136
-
-
2142700028
-
K+ channels as targets for specific immunomodulation
-
Chandy KG, Wulff H, Beeton C, Pennington M, Gutman GA, Cahalan MD. K+ channels as targets for specific immunomodulation. Trends Pharmacol Sci 2004 25 : 280 289.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 280-289
-
-
Chandy, K.G.1
Wulff, H.2
Beeton, C.3
Pennington, M.4
Gutman, G.A.5
Cahalan, M.D.6
-
137
-
-
0034614940
-
Target-cell contact activates a highly selective capacitative calcium entry pathway in cytotoxic T lymphocytes
-
Zweifach A. Target-cell contact activates a highly selective capacitative calcium entry pathway in cytotoxic T lymphocytes. J Cell Biol 2000 148 : 603 614.
-
(2000)
J Cell Biol
, vol.148
, pp. 603-614
-
-
Zweifach, A.1
-
138
-
-
50249165416
-
Hair loss and defective T- and B-cell function in mice lacking ORAI1
-
Gwack Y, et al. Hair loss and defective T- and B-cell function in mice lacking ORAI1. Mol Cell Biol 2008 28 : 5209 5222.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5209-5222
-
-
Gwack, Y.1
-
139
-
-
34247339504
-
Biochemical and functional characterization of Orai proteins
-
Gwack Y, et al. Biochemical and functional characterization of Orai proteins. J Biol Chem 2007 282 : 16232 16243.
-
(2007)
J Biol Chem
, vol.282
, pp. 16232-16243
-
-
Gwack, Y.1
-
140
-
-
59849117077
-
Re-organization of mitochondria at the NK cell immune synapse
-
Abarca-Rojano E, Muñiz-Hernández S, Moreno-Altamirano MM, Mondragón-Flores R, Enriquez-Rincón F, Sánchez- García FJ. Re-organization of mitochondria at the NK cell immune synapse. Immunol Lett 2009 122 : 18 25.
-
(2009)
Immunol Lett
, vol.122
, pp. 18-25
-
-
Abarca-Rojano, E.1
Muñiz-Hernández, S.2
Moreno-Altamirano, M.M.3
Mondragón-Flores, R.4
Enriquez-Rincón, F.5
Sánchez- García, F.J.6
-
141
-
-
0030061745
-
Interaction of cytotoxic T lymphocytes and guinea pig ventricular myocytes. Pharmacological modulation by blocking K+ currents in cytotoxic T lymphocytes
-
Felzen B, Lavy R, Garcia M, Berke G, Gardner P, Binah O. Interaction of cytotoxic T lymphocytes and guinea pig ventricular myocytes. Pharmacological modulation by blocking K+ currents in cytotoxic T lymphocytes. Circ Res 1996 78 : 253 261.
-
(1996)
Circ Res
, vol.78
, pp. 253-261
-
-
Felzen, B.1
Lavy, R.2
Garcia, M.3
Berke, G.4
Gardner, P.5
Binah, O.6
-
142
-
-
0037653363
-
Immunosuppressive effects of a Kv1.3 inhibitor
-
Shah K, Tom Blake J, Huang C, Fischer P, Koo GC. Immunosuppressive effects of a Kv1.3 inhibitor. Cell Immunol 2003 221 : 100 106.
-
(2003)
Cell Immunol
, vol.221
, pp. 100-106
-
-
Shah, K.1
Tom Blake, J.2
Huang, C.3
Fischer, P.4
Koo, G.C.5
-
143
-
-
0027507325
-
The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes
-
Dupuis M, Schaerer E, Krause K, Tschopp J. The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes. J Exp Med 1993 177 : 1 7.
-
(1993)
J Exp Med
, vol.177
, pp. 1-7
-
-
Dupuis, M.1
Schaerer, E.2
Krause, K.3
Tschopp, J.4
-
144
-
-
41149089645
-
Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation
-
Lioudyno MI, et al. Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation. Proc Natl Acad Sci USA 2008 150 : 2011 2016.
-
(2008)
Proc Natl Acad Sci USA
, vol.150
, pp. 2011-2016
-
-
Lioudyno, M.I.1
-
145
-
-
51349085429
-
Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps
-
Barr VA, et al. Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal caps. Mol Biol Cell 2008 19 : 2802 2817.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2802-2817
-
-
Barr, V.A.1
-
146
-
-
0021766912
-
Calmodulin interaction with cytoplasmic and flagellar dynein: calcium-dependent binding and stimulation of adenosinetriphosphatase activity
-
Hisanaga S, Pratt MM. Calmodulin interaction with cytoplasmic and flagellar dynein: calcium-dependent binding and stimulation of adenosinetriphosphatase activity. Biochemistry 1984 23 : 3032 3037.
-
(1984)
Biochemistry
, vol.23
, pp. 3032-3037
-
-
Hisanaga, S.1
Pratt, M.M.2
-
148
-
-
19744382953
-
The MAP2/Tau family of microtubule-associated proteins
-
Dehmelt L, Halpain S. The MAP2/Tau family of microtubule-associated proteins. Genome Biol 2005 6 : 204.
-
(2005)
Genome Biol
, vol.6
, pp. 204
-
-
Dehmelt, L.1
Halpain, S.2
-
149
-
-
0037441341
-
The voltage- and time-dependent blocking effect of trifluoperazine on T lymphocyte Kv1.3 channels
-
Teisseyre A, Michalak K. The voltage- and time-dependent blocking effect of trifluoperazine on T lymphocyte Kv1.3 channels. Biochem Pharmacol 2003 65 : 551 561.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 551-561
-
-
Teisseyre, A.1
Michalak, K.2
-
150
-
-
34547124854
-
Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis
-
Grybko MJ, Bartnik JP, Wurth GA, Pores-Fernando AT, Zweifach A. Calcineurin activation is only one calcium-dependent step in cytotoxic T lymphocyte granule exocytosis. J Biol Chem 2007 282 : 18009 18017.
-
(2007)
J Biol Chem
, vol.282
, pp. 18009-18017
-
-
Grybko, M.J.1
Bartnik, J.P.2
Wurth, G.A.3
Pores-Fernando, A.T.4
Zweifach, A.5
-
151
-
-
6344284899
-
2+/ calcineurin-NFAT-mediated signaling
-
2+/calcineurin-NFAT-mediated signaling. Mol Cells 2004 18 : 1 9.
-
(2004)
Mol Cells
, vol.18
, pp. 1-9
-
-
Im, S.H.1
Rao, A.2
-
152
-
-
20644466433
-
NFAT proteins: key regulators of T-cell development and function
-
Macian F. NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 2005 5 : 472 484.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
153
-
-
0032849010
-
Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A
-
Aramburu J, Yaffe MB, Lopez-Rodriguez C, Cantley LC, Hogan PG, Rao A. Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science 1999 285 : 2129 2133.
-
(1999)
Science
, vol.285
, pp. 2129-2133
-
-
Aramburu, J.1
Yaffe, M.B.2
Lopez-Rodriguez, C.3
Cantley, L.C.4
Hogan, P.G.5
Rao, A.6
-
154
-
-
0032575666
-
Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells
-
Groblewski GE, Yoshida M, Bragado MJ, Ernst SA, Leykam J, Williams JA. Purification and characterization of a novel physiological substrate for calcineurin in mammalian cells. J Biol Chem 1998 273 : 22 738 22 744.
-
(1998)
J Biol Chem
, vol.273
, pp. 22738-22744
-
-
Groblewski, G.E.1
Yoshida, M.2
Bragado, M.J.3
Ernst, S.A.4
Leykam, J.5
Williams, J.A.6
-
155
-
-
0030965369
-
Regulation of calcium-induced exocytosis from gastric chief cells by protein phosphatase-2B (calcineurin)
-
Raufman J-P, Malhotra R, Raffaniello RD. Regulation of calcium-induced exocytosis from gastric chief cells by protein phosphatase-2B (calcineurin). Biochim Biophys Acta 1997 1357 : 73 80.
-
(1997)
Biochim Biophys Acta
, vol.1357
, pp. 73-80
-
-
Raufman J-P1
Malhotra, R.2
Raffaniello, R.D.3
-
156
-
-
0037024694
-
2+-dependent dephosphorylation of kinesin heavy chain on beta -granules in pancreatic beta -cells. Implications for regulated β-granule transport and insulin exocytosis
-
2+-dependent dephosphorylation of kinesin heavy chain on beta -granules in pancreatic beta -cells. Implications for regulated β-granule transport and insulin exocytosis. J Biol Chem 2002 277 : 24232 24242.
-
(2002)
J Biol Chem
, vol.277
, pp. 24232-24242
-
-
Donelan, M.J.1
-
157
-
-
0025086823
-
Regulation of organelle transport in melanophores by calcineurin
-
Thaler C, Haimo L. Regulation of organelle transport in melanophores by calcineurin. J Cell Biol 1990 111 : 1939 1948.
-
(1990)
J Cell Biol
, vol.111
, pp. 1939-1948
-
-
Thaler, C.1
Haimo, L.2
-
158
-
-
0021842984
-
Dephosphorylation of microtubule-associated protein 2, tau factor, and tubulin by calcineurin
-
Goto S, Yamamoto H, Fukunaga K, Iwasa T, Matsukado Y, Miyamoto E. Dephosphorylation of microtubule-associated protein 2, tau factor, and tubulin by calcineurin. J Neurochem 1985 45 : 276 283.
-
(1985)
J Neurochem
, vol.45
, pp. 276-283
-
-
Goto, S.1
Yamamoto, H.2
Fukunaga, K.3
Iwasa, T.4
Matsukado, Y.5
Miyamoto, E.6
-
159
-
-
0030467967
-
The C2 domain calcium-binding motif: structural and functional diversity
-
Nalefski EA, Falke JJ. The C2 domain calcium-binding motif: structural and functional diversity. Protein Sci 1996 5 : 2375 2390.
-
(1996)
Protein Sci
, vol.5
, pp. 2375-2390
-
-
Nalefski, E.A.1
Falke, J.J.2
-
160
-
-
0036304982
-
2+) sensor that triggers exocytosis?
-
2+) sensor that triggers exocytosis? Nat Rev Mol Cell Biol 2002 3 : 498 508.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 498-508
-
-
Chapman, E.R.1
-
161
-
-
33845210867
-
SNAREing immunity: the role of SNAREs in the immune system
-
Stow JL, Manderson AP, Murray RZ. SNAREing immunity: the role of SNAREs in the immune system. Nat Rev Immunol 2006 6 : 919 929.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 919-929
-
-
Stow, J.L.1
Manderson, A.P.2
Murray, R.Z.3
-
162
-
-
28244440230
-
Cytotoxic T lymphocyte exocytosis: bring on the SNAREs
-
Hong W. Cytotoxic T lymphocyte exocytosis: bring on the SNAREs. Trends Cell Biol 2005 15 : 644 650.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 644-650
-
-
Hong, W.1
-
163
-
-
34548814973
-
Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients
-
Bryceson YT, et al. Defective cytotoxic lymphocyte degranulation in syntaxin-11 deficient familial hemophagocytic lymphohistiocytosis 4 (FHL4) patients. Blood 2007 110 : 1906 1915.
-
(2007)
Blood
, vol.110
, pp. 1906-1915
-
-
Bryceson, Y.T.1
-
164
-
-
20144363940
-
Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11
-
zur Stadt U, et al. Linkage of familial hemophagocytic lymphohistiocytosis (FHL) type-4 to chromosome 6q24 and identification of mutations in syntaxin 11. Hum Mol Genet 2005 14 : 827 834.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 827-834
-
-
Zur Stadt, U.1
-
165
-
-
35748962621
-
Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity
-
Arneson LN, Brickshawana A, Segovis CM, Schoon RA, Dick CJ, Leibson PJ. Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity. J Immunol 2007 179 : 3397 3401.
-
(2007)
J Immunol
, vol.179
, pp. 3397-3401
-
-
Arneson, L.N.1
Brickshawana, A.2
Segovis, C.M.3
Schoon, R.A.4
Dick, C.J.5
Leibson, P.J.6
-
166
-
-
33846498689
-
Expression and function of synaptotagmin VII in CTLs
-
Fowler KT, Andrews NW, Huleatt JW. Expression and function of synaptotagmin VII in CTLs. J Immunol 2007 178 : 1498 1504.
-
(2007)
J Immunol
, vol.178
, pp. 1498-1504
-
-
Fowler, K.T.1
Andrews, N.W.2
Huleatt, J.W.3
-
168
-
-
0037040890
-
Synaptotagmins: why so many?
-
Sudhof TC. Synaptotagmins: why so many? J Biol Chem 2002 277 : 7629 7932.
-
(2002)
J Biol Chem
, vol.277
, pp. 7629-7932
-
-
Sudhof, T.C.1
-
169
-
-
34247880547
-
Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4
-
Ménager MM, et al. Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4. Nat Immun 2007 8 : 257 267.
-
(2007)
Nat Immun
, vol.8
, pp. 257-267
-
-
Ménager, M.M.1
-
170
-
-
10744224641
-
Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)
-
Feldmann J, et al. Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3). Cell 2003 115 : 461 473.
-
(2003)
Cell
, vol.115
, pp. 461-473
-
-
Feldmann, J.1
-
171
-
-
40449092959
-
Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse
-
Holt O, et al. Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. Traffic 2008 9 : 446 457.
-
(2008)
Traffic
, vol.9
, pp. 446-457
-
-
Holt, O.1
-
172
-
-
35748984692
-
Munc18-1 in secretion: lonely Munc joins SNARE team and takes control
-
Toonen RF, Verhage M. Munc18-1 in secretion: lonely Munc joins SNARE team and takes control. Trends Neurosci 2007 30 : 564 572.
-
(2007)
Trends Neurosci
, vol.30
, pp. 564-572
-
-
Toonen, R.F.1
Verhage, M.2
-
173
-
-
0034805325
-
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins
-
Fukuda M, Mikoshiba K. Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins. Biochem Biophys Res Commun 2001 281 : 1226 1233.
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 1226-1233
-
-
Fukuda, M.1
Mikoshiba, K.2
-
175
-
-
4043075637
-
2+sensor/effector complex that controls short-term synaptic plasticity
-
2+sensor/ effector complex that controls short-term synaptic plasticity. Cell 2004 118 : 389 401.
-
(2004)
Cell
, vol.118
, pp. 389-401
-
-
Junge, H.J.1
-
176
-
-
44449130054
-
2+-dependent secretory lysosome exocytosis in mast cells
-
2+-dependent secretory lysosome exocytosis in mast cells. J Immunol 2008 180 : 4774 4784.
-
(2008)
J Immunol
, vol.180
, pp. 4774-4784
-
-
Higashio, H.1
-
177
-
-
33645861074
-
DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties
-
Groffen AJ, Friedrich R, Brian EC, Ashery U, Verhage M. DOC2A and DOC2B are sensors for neuronal activity with unique calcium-dependent and kinetic properties. J Neurochem 2006 97 : 818 833.
-
(2006)
J Neurochem
, vol.97
, pp. 818-833
-
-
Groffen, A.J.1
Friedrich, R.2
Brian, E.C.3
Ashery, U.4
Verhage, M.5
-
178
-
-
0032559586
-
Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism
-
Lowin-Kropf B, Shapiro VS, Weiss A. Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism. J Cell Biol 1998 140 : 861 871.
-
(1998)
J Cell Biol
, vol.140
, pp. 861-871
-
-
Lowin-Kropf, B.1
Shapiro, V.S.2
Weiss, A.3
-
179
-
-
0029670089
-
Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes
-
Baier-Bitterlich G, et al. Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes. Mol Cell Biol 1996 16 : 1842 1850.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1842-1850
-
-
Baier-Bitterlich, G.1
-
180
-
-
0029096601
-
Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells
-
Parekh AB, Penner R. Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells. Proc Natl Acad Sci USA 1995 92 : 7907 7911.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7907-7911
-
-
Parekh, A.B.1
Penner, R.2
-
181
-
-
0038620475
-
2+mobilization and NFAT cell activation in primary mouse T cells
-
2+mobilization and NFAT cell activation in primary mouse T cells. J Exp Med 2003 197 : 1525 1535.
-
(2003)
J Exp Med
, vol.197
, pp. 1525-1535
-
-
Pfeifhofer, C.1
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