β2 integrin induces TCRζ-Syk-Phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells

Journal of Immunology

Volumn 186, Issue 5, 2011, Pages 2998-3005

  March, Michael E ^a   Long, Eric O ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 INTEGRIN; CD16 ANTIGEN; FOCAL ADHESION KINASE 2; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 2; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; PAXILLIN; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE C; PROTEIN KINASE SYK; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ZETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CONTROLLED STUDY; DEGRANULATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; NATURAL KILLER CELL; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, CD18; CALCIUM SIGNALING; CELL DEGRANULATION; CELL LINE; CELL POLARITY; CELLS, CULTURED; CYTOPLASMIC GRANULES; DROSOPHILA MELANOGASTER; GPI-LINKED PROTEINS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MEMBRANE PROTEINS; PAXILLIN; PERFORIN; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, IGG; TYROSINE;

EID: 79952768718     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1002438     Document Type: Article

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