The Vav-Rac1 pathway in cytotoxic lymphocytes regulates the generation of cell-mediated killing

Journal of Experimental Medicine

Volumn 188, Issue 3, 1998, Pages 549-559

  Billadeau, Daniel D ^a   Brumbaugh, Kathryn M ^a   Dick, Christopher J ^a   Schoon, Renee A ^a   Bustelo, Xose R ^b   Leibson, Paul J ^a  

^a MAYO CLINIC   (United States)

^b STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Granule exocytosis; Natural killer cell; Rac1; Sigual transduction; Vav

Indexed keywords

ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; ARTICLE; CELL ADHESION; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; EXOCYTOSIS; HUMAN; HUMAN CELL; NATURAL KILLER CELL; NATURAL KILLER CELL MEDIATED CYTOTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

CELL CYCLE PROTEINS; CELLS, CULTURED; CYTOTOXICITY, IMMUNOLOGIC; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HUMANS; KILLER CELLS, NATURAL; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-VAV; RAC GTP-BINDING PROTEINS; RECOMBINANT FUSION PROTEINS; TYROSINE;

EID: 0032479968     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.3.549     Document Type: Article

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