Impaired Ptdlns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle trafficking

Nature

Volumn 431, Issue 7007, 2004, Pages 415-422

  Di Paolo, Gilbert ^a   Moskowitz, Howard S ^b   Gipson, Keith ^a   Wenk, Markus R ^a   Voronov, Sergey ^a   Obayashi, Masanori ^a   Flavell, Richard ^a   Fitzsimonds, Reiko M ^a   Ryan, Timothy A ^b   De Camill, Pietro ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOCHEMISTRY; CELLS; CYTOLOGY; MEMBRANES; MOLECULAR DYNAMICS; PROTEINS; REACTION KINETICS; SYNTHESIS (CHEMICAL);

CELL REGULATION; CYTOSOLS; EXOCYTOSIS; MESSENGER MOLECULES;

PLATINUM COMPOUNDS;

CELL PROTEIN; CLATHRIN; MEMBRANE PROTEIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; 1-PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE; PHOSPHATIDYLINOSITOL 4 PHOSPHATE KINASE; PHOSPHATIDYLINOSITOL PHOSPHATE, PTDINS(4,5)P2; PHOSPHOTRANSFERASE; POLYPHOSPHOINOSITIDE;

BIOLOGY; NEUROLOGY;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; COATED VESICLE; CONTROLLED STUDY; CYTOSOL; DEPOLARIZATION; EMBRYO; ENDOCYTOSIS; ENDOSOME; EXOCYTOSIS; FREQUENCY MODULATION; LETHALITY; LIPID BRAIN LEVEL; MOUSE; NERVE ENDING; NONHUMAN; PERINATAL PERIOD; PHOSPHOLIPID METABOLISM; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN INTERACTION; REGULATORY MECHANISM; SECOND MESSENGER; SYNAPSE VESICLE; SYNAPTIC INHIBITION; SYNAPTIC TRANSMISSION; ACTION POTENTIAL; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; ELECTRIC CONDUCTIVITY; GENE DELETION; GENETICS; KINETICS; METABOLISM; MOUSE MUTANT; NERVE CELL; SYNAPTOSOME; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CLATHRIN; ELECTRIC CONDUCTIVITY; ENDOCYTOSIS; EXOCYTOSIS; GENE DELETION; KINETICS; MICE; MICE, KNOCKOUT; NEURONS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PRESYNAPTIC TERMINALS; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES;

EID: 4644262299     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02896     Document Type: Article

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