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Volumn 19, Issue 5, 2003, Pages 253-256

Does the intrinsic instability of aneuploid genomes have a causal role in cancer?

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ANEUGEN;

EID: 0037406990     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(03)00057-X     Document Type: Article
Times cited : (83)

References (38)
  • 1
    • 0029111860 scopus 로고
    • Theodor Boveri and the origin of malignant tumors
    • Manchester K.L. Theodor Boveri and the origin of malignant tumors. Trends Cell Biol. 5:1995;384-387.
    • (1995) Trends Cell Biol. , vol.5 , pp. 384-387
    • Manchester, K.L.1
  • 2
    • 0035830497 scopus 로고    scopus 로고
    • Spontaneous DNA damage, genome instability, and cancer - when DNA replication escapes control
    • Schär P. Spontaneous DNA damage, genome instability, and cancer - when DNA replication escapes control. Cell. 104:2001;329-332.
    • (2001) Cell , vol.104 , pp. 329-332
    • Schär, P.1
  • 3
    • 0037178734 scopus 로고    scopus 로고
    • Debate surges over the origins of genomic defects in cancer
    • Marx J. Debate surges over the origins of genomic defects in cancer. Science. 297:2002;544-546.
    • (2002) Science , vol.297 , pp. 544-546
    • Marx, J.1
  • 4
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C., et al. Genetic instabilities in human cancers. Nature. 396:1998;643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1
  • 5
    • 0033396407 scopus 로고    scopus 로고
    • How aneuploidy may cause cancer and genetic instability
    • Duesberg P., et al. How aneuploidy may cause cancer and genetic instability. Anticancer Res. 19:1999;4887-4906.
    • (1999) Anticancer Res. , vol.19 , pp. 4887-4906
    • Duesberg, P.1
  • 6
    • 0034525948 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Sen S. Aneuploidy and cancer. Curr. Opin. Oncol. 12:2000;82-88.
    • (2000) Curr. Opin. Oncol. , vol.12 , pp. 82-88
    • Sen, S.1
  • 7
    • 0029028701 scopus 로고
    • Cancer: The rise of the genetic paradigm
    • Bishop J.M. Cancer: the rise of the genetic paradigm. Genes Dev. 9:1995;1309-1315.
    • (1995) Genes Dev. , vol.9 , pp. 1309-1315
    • Bishop, J.M.1
  • 8
    • 0028850457 scopus 로고
    • Asbestos and mesothelioma: Genetic lessons from a tragedy
    • Knudson A. Asbestos and mesothelioma: genetic lessons from a tragedy. Proc. Natl. Acad. Sci. U. S. A. 92:1995;10819-10820.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 10819-10820
    • Knudson, A.1
  • 10
    • 0032712463 scopus 로고    scopus 로고
    • Chromosome aberrations in wheat nullisomic-tetrasomic and ditelosomic lines
    • Devos K., et al. Chromosome aberrations in wheat nullisomic-tetrasomic and ditelosomic lines. Cereal Res. Commun. 27:1999;231-239.
    • (1999) Cereal Res. Commun. , vol.27 , pp. 231-239
    • Devos, K.1
  • 11
    • 0029199676 scopus 로고
    • B chromosomes in plants
    • Jones R.N. B chromosomes in plants. New Phytol. 131:1995;411-434.
    • (1995) New Phytol. , vol.131 , pp. 411-434
    • Jones, R.N.1
  • 12
    • 0036943583 scopus 로고    scopus 로고
    • Origin of an apparent B chromosome by mutation, chromosome fragmentation and specific DNA sequence amplification
    • Dhar M., et al. Origin of an apparent B chromosome by mutation, chromosome fragmentation and specific DNA sequence amplification. Chromosoma. 111:2002;332-340.
    • (2002) Chromosoma , vol.111 , pp. 332-340
    • Dhar, M.1
  • 13
    • 0030238423 scopus 로고    scopus 로고
    • Structural instability of a transgene locus in tobacco is associated with aneuploidy
    • Papp I., et al. Structural instability of a transgene locus in tobacco is associated with aneuploidy. Plant J. 10:1996;469-478.
    • (1996) Plant J. , vol.10 , pp. 469-478
    • Papp, I.1
  • 14
    • 0035956878 scopus 로고    scopus 로고
    • Mechanisms underlying loses of heterozygosity in human colorectal cancers
    • Thiagalingam S., et al. Mechanisms underlying loses of heterozygosity in human colorectal cancers. Proc. Natl. Acad. Sci. U. S. A. 98:2001;2698-2702.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 2698-2702
    • Thiagalingam, S.1
  • 15
    • 0030014783 scopus 로고    scopus 로고
    • DNA topoisomerases
    • Wang J. DNA topoisomerases. Annu. Rev. Biochem. 65:1996;635-692.
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 635-692
    • Wang, J.1
  • 16
    • 0344413285 scopus 로고
    • Dysfunction of chromosomal loop attachment sites: Illegitimate recombination linked to matrix association regions and topoisomerase II
    • Sperry A., et al. Dysfunction of chromosomal loop attachment sites: illegitimate recombination linked to matrix association regions and topoisomerase II. Proc. Natl. Acad. Sci. U. S. A. 86:1989;5497-5501.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 5497-5501
    • Sperry, A.1
  • 17
    • 0027996347 scopus 로고
    • Breakpoint junctions of chromosome 9p deletions in two human glioma cell lines
    • Pomykala H., et al. Breakpoint junctions of chromosome 9p deletions in two human glioma cell lines. Mol. Cell. Biol. 14:1994;7604-7610.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7604-7610
    • Pomykala, H.1
  • 18
    • 0037022636 scopus 로고    scopus 로고
    • Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia
    • Zhang Y., et al. Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia. Proc. Natl. Acad. Sci. U. S. A. 99:2002;3070-3075.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 3070-3075
    • Zhang, Y.1
  • 19
    • 0037174667 scopus 로고    scopus 로고
    • A matter of dosage
    • Fodde R., Smits R. A matter of dosage. Science. 298:2002;761-763.
    • (2002) Science , vol.298 , pp. 761-763
    • Fodde, R.1    Smits, R.2
  • 20
    • 0035902108 scopus 로고    scopus 로고
    • Genome maintenance mechanisms for preventing cancer
    • Hoeijmakers J. Genome maintenance mechanisms for preventing cancer. Nature. 411:2001;366-373.
    • (2001) Nature , vol.411 , pp. 366-373
    • Hoeijmakers, J.1
  • 21
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones P., Baylin S. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3:2002;415-428.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.1    Baylin, S.2
  • 22
    • 0034499304 scopus 로고    scopus 로고
    • Recognition and silencing of repeated DNA
    • Hsieh J., Fire A. Recognition and silencing of repeated DNA. Annu. Rev. Genet. 34:2000;187-204.
    • (2000) Annu. Rev. Genet. , vol.34 , pp. 187-204
    • Hsieh, J.1    Fire, A.2
  • 23
    • 0031046267 scopus 로고    scopus 로고
    • A unique downregulation of h2-calponin gene expression in Down syndrome: A possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21
    • Kuromitsu J., et al. A unique downregulation of h2-calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21. Mol. Cell. Biol. 17:1997;707-721.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 707-721
    • Kuromitsu, J.1
  • 24
    • 0030929136 scopus 로고    scopus 로고
    • Gene identification and DNA sequence analysis in the GC-poor 20 megabase region of human chromosome 21
    • Yu J., et al. Gene identification and DNA sequence analysis in the GC-poor 20 megabase region of human chromosome 21. Proc. Natl. Acad. Sci. U. S. A. 94:1997;6862-6867.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 6862-6867
    • Yu, J.1
  • 25
    • 0037115492 scopus 로고    scopus 로고
    • Transcriptome analysis of human autosomal trisomy
    • FitzPatrick D., et al. Transcriptome analysis of human autosomal trisomy. Hum. Mol. Genet. 11:2002;3249-3256.
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 3249-3256
    • FitzPatrick, D.1
  • 26
    • 0028574084 scopus 로고
    • Trans-acting dosage effects on the expression of model gene systems in maize aneuploids
    • Guo M., Birchler J. Trans-acting dosage effects on the expression of model gene systems in maize aneuploids. Science. 266:1994;1999-2002.
    • (1994) Science , vol.266 , pp. 1999-2002
    • Guo, M.1    Birchler, J.2
  • 27
    • 0033153475 scopus 로고    scopus 로고
    • Mouse autosomal trisomy, two's company, three's a crowd
    • Hernandez D., Fisher E. Mouse autosomal trisomy, two's company, three's a crowd. Trends Genet. 15:1999;241-247.
    • (1999) Trends Genet. , vol.15 , pp. 241-247
    • Hernandez, D.1    Fisher, E.2
  • 28
    • 0035252562 scopus 로고    scopus 로고
    • Too much of a good thing: Mechanisms of gene action in Down syndrome
    • Reeves R., et al. Too much of a good thing: mechanisms of gene action in Down syndrome. Trends Genet. 17:2001;83-88.
    • (2001) Trends Genet. , vol.17 , pp. 83-88
    • Reeves, R.1
  • 29
    • 0034682403 scopus 로고    scopus 로고
    • The DNA sequence of human chromosome 21
    • Hattori M., et al. The DNA sequence of human chromosome 21. Nature. 405:2000;311-319.
    • (2000) Nature , vol.405 , pp. 311-319
    • Hattori, M.1
  • 30
    • 0028907778 scopus 로고
    • Cytogenetic and molecular studies of Down syndrome individuals with leukemia
    • Shen J., et al. Cytogenetic and molecular studies of Down syndrome individuals with leukemia. Am. J. Hum. Genet. 56:1995;915-925.
    • (1995) Am. J. Hum. Genet. , vol.56 , pp. 915-925
    • Shen, J.1
  • 31
    • 0029436446 scopus 로고
    • Down syndrome and leukemia, an update
    • Drabkin H., Erickson P. Down syndrome and leukemia, an update. Prog. Clin. Biol. Res. 393:1995;169-176.
    • (1995) Prog. Clin. Biol. Res. , vol.393 , pp. 169-176
    • Drabkin, H.1    Erickson, P.2
  • 32
    • 0034854751 scopus 로고    scopus 로고
    • Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion: A molecular cytogenetics study
    • Ma S., et al. Characterization of additional genetic events in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion: a molecular cytogenetics study. Leukemia. 15:2001;1442-1447.
    • (2001) Leukemia , vol.15 , pp. 1442-1447
    • Ma, S.1
  • 33
    • 0342905433 scopus 로고    scopus 로고
    • Risks of leukaemia and solid tumors in individuals with Down's syndrome
    • Hasle H., et al. Risks of leukaemia and solid tumors in individuals with Down's syndrome. Lancet. 355:2000;165-169.
    • (2000) Lancet , vol.355 , pp. 165-169
    • Hasle, H.1
  • 34
    • 0031607510 scopus 로고    scopus 로고
    • Another reason to look for tumor suppressor genes on chromosome 21
    • Satgé D. Another reason to look for tumor suppressor genes on chromosome 21. Genes Chromosomes Cancer. 21:1998;1.
    • (1998) Genes Chromosomes Cancer , vol.21 , pp. 1
    • Satgé, D.1
  • 35
    • 0036846180 scopus 로고    scopus 로고
    • The role of double-strand break-induced allelic homologous recombination in somatic plant cells
    • Gisler B., et al. The role of double-strand break-induced allelic homologous recombination in somatic plant cells. Plant J. 32:2002;277-284.
    • (2002) Plant J. , vol.32 , pp. 277-284
    • Gisler, B.1
  • 36
    • 0036831681 scopus 로고    scopus 로고
    • Centrosome aberrations: Cause or consequence of cancer progression?
    • Nigg E. Centrosome aberrations: cause or consequence of cancer progression? Nat. Rev. Cancer. 2:2002;815-825.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 815-825
    • Nigg, E.1
  • 37
    • 0037037806 scopus 로고    scopus 로고
    • Chromosome instability in human lung cancers: Possible underlying mechanisms and potential consequences in the pathogenesis
    • Masuda A., Takahashi T. Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis. Oncogene. 21:2002;6884-6897.
    • (2002) Oncogene , vol.21 , pp. 6884-6897
    • Masuda, A.1    Takahashi, T.2
  • 38
    • 0035198088 scopus 로고    scopus 로고
    • Cancer: The evolved consequence of a destabilized genome
    • Anderson G., et al. Cancer: the evolved consequence of a destabilized genome. BioEssays. 23:2001;1037-1046.
    • (2001) BioEssays , vol.23 , pp. 1037-1046
    • Anderson, G.1


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