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Volumn 11, Issue 11, 2010, Pages 812-

Missing heritability and stochastic genome alterations

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ALZHEIMER DISEASE; AUTISM; EPIGENETICS; GENE STRUCTURE; GENETIC DISORDER; GENETIC VARIABILITY; GENOMICS; GENOTYPE ENVIRONMENT INTERACTION; HERITABILITY; KARYOTYPE; LETTER; MUTATION; NEOPLASM; POINT MUTATION; PRIORITY JOURNAL;

EID: 77958102017     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg2809-c3     Document Type: Letter
Times cited : (48)

References (12)
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    • Missing heritability and strategies for finding the underlying causes of complex disease
    • Eichler, E. E. et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nature Rev. Genet. 11, 446-450 (2010).
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    • Eichler, E.E.1
  • 2
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    • The genome-centric concept: Resynthesis of evolutionary theory
    • Heng, H. H. The genome-centric concept: resynthesis of evolutionary theory. Bioessays 31, 512-525 (2009).
    • (2009) Bioessays , vol.31 , pp. 512-525
    • Heng, H.H.1
  • 3
    • 34547614739 scopus 로고    scopus 로고
    • Elimination of altered karyotypes by sexual reproduction preserves species identity
    • Heng, H. H. Elimination of altered karyotypes by sexual reproduction preserves species identity. Genome 50, 517-524 (2007).
    • (2007) Genome , vol.50 , pp. 517-524
    • Heng, H.H.1
  • 4
    • 34347349069 scopus 로고    scopus 로고
    • Genomic rearrangements and sporadic disease
    • Lupski, J. R. Genomic rearrangements and sporadic disease. Nature Genet. 39, S43-S47 (2007).
    • (2007) Nature Genet , vol.39
    • Lupski, J.R.1
  • 7
    • 77951702343 scopus 로고    scopus 로고
    • Genetic heterogeneity in human disease
    • McClellan, J. & King, M. C. Genetic heterogeneity in human disease. Cell 141, 210-217 (2010).
    • (2010) Cell , vol.141 , pp. 210-217
    • McClellan, J.1    King, M.C.2
  • 8
    • 33745612099 scopus 로고    scopus 로고
    • Stochastic cancer progression driven by non-clonal chromosome aberrations
    • Heng, H. H. et al. Stochastic cancer progression driven by non-clonal chromosome aberrations. J. Cell. Physiol. 208, 461-472 (2006).
    • (2006) J. Cell. Physiol , vol.208 , pp. 461-472
    • Heng, H.H.1
  • 9
    • 34547641984 scopus 로고    scopus 로고
    • Cancer genome sequencing: The challenges ahead
    • Heng, H. H. Cancer genome sequencing: the challenges ahead. Bioessays 29, 783-794 (2007).
    • (2007) Bioessays , vol.29 , pp. 783-794
    • Heng, H.H.1
  • 10
    • 77951734539 scopus 로고    scopus 로고
    • The evolutionary mechanism of cancer
    • Heng, H. H. et al. The evolutionary mechanism of cancer. J. Cell. Biochem. 109, 1072-1084 (2010).
    • (2010) J. Cell. Biochem , vol.109 , pp. 1072-1084
    • Heng, H.H.1
  • 11
    • 62149092895 scopus 로고    scopus 로고
    • Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer
    • Ye, C. J. et al. Genome based cell population heterogeneity promotes tumorigenicity: the evolutionary mechanism of cancer. J. Cell. Physiol. 219, 288-300 (2009).
    • (2009) J. Cell. Physiol. , vol.219 , pp. 288-300
    • Ye, C.J.1
  • 12
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    • Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy
    • Lupski, J. R. et al. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. N. Engl. J. Med. 362, 1181-1191 (2010).
    • (2010) N. Engl. J. Med. , vol.362 , pp. 1181-1191
    • Lupski, J.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.