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Volumn 139, Issue 3, 2013, Pages 144-157

Karyotype heterogeneity and unclassified chromosomal abnormalities

Author keywords

Chromosomal abnormalities; Chromosomal instability; Chromosome fragmentation; Defective mitotic figures; Genome chaos; Genome Theory; Karyotype heterogeneity; Non clonal chromosome aberration

Indexed keywords

CELL NUCLEUS; CELL STRUCTURE; CHROMATIN; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; CLONAL EVOLUTION; DNA FRAGMENTATION; GENETIC HETEROGENEITY; GENETIC SCREENING; GENOME ANALYSIS; HUMAN; KARYOTYPE; KARYOTYPE EVOLUTION; METAPHASE; METAPHASE CHROMOSOME; MICRONUCLEUS; MITOSIS; NATURAL SELECTION; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOMATIC CELL; ARTICLE; CANCER GENETICS; CHROMOSOME ANALYSIS; GENOMIC INSTABILITY; GENOMICS; KARYOTYPING;

EID: 84871688584     PISSN: 14248581     EISSN: 1424859X     Source Type: Journal    
DOI: 10.1159/000348682     Document Type: Review
Times cited : (77)

References (60)
  • 1
    • 78649990353 scopus 로고    scopus 로고
    • Are we genomic mosaics? Variations of the genome of somatic cells can contribute to diversify our phenotypes
    • Astolfi PA, Salamini F, Sgaramella V: Are we genomic mosaics? Variations of the genome of somatic cells can contribute to diversify our phenotypes. Curr Genomics 11: 379-386 (2010).
    • (2010) Curr Genomics , vol.11 , pp. 379-386
    • Astolfi, P.A.1    Salamini, F.2    Sgaramella, V.3
  • 3
    • 80053592718 scopus 로고    scopus 로고
    • The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): The role of life-style, host factors, occupational exposures, health status, and assay protocol
    • Bonassi S, Coskun E, Ceppi M, Lando C, Bolognesi C, et al: The HUman MicroNucleus project on eXfoLiated buccal cells (HUMN(XL)): The role of life-style, host factors, occupational exposures, health status, and assay protocol. Mutat Res 728: 88-97 (2011).
    • (2011) Mutat Res , vol.728 , pp. 88-97
    • Bonassi, S.1    Coskun, E.2    Ceppi, M.3    Lando, C.4    Bolognesi, C.5
  • 4
    • 79954496012 scopus 로고    scopus 로고
    • Malignant fibrous histiocytoma two years after autologous stem cell transplant for Hodgkin lymphoma: Evidence for genomic instability
    • Chandrakasan S, Ye CJ, Chitlur M, Mohamed AN, Rabah R, et al: Malignant fibrous histiocytoma two years after autologous stem cell transplant for Hodgkin lymphoma: Evidence for genomic instability. Pediatr Blood Cancer 56: 1143-1145 (2011).
    • (2011) Pediatr Blood Cancer , vol.56 , pp. 1143-1145
    • Chandrakasan, S.1    Ye, C.J.2    Chitlur, M.3    Mohamed, A.N.4    Rabah, R.5
  • 5
    • 34249734165 scopus 로고    scopus 로고
    • Chromosomal chaos and cancer
    • Duesberg P: Chromosomal chaos and cancer. Sci Am 296:52-59 (2007). (Pubitemid 46833366)
    • (2007) Scientific American , vol.296 , Issue.5 , pp. 52-59
    • Duesberg, P.1
  • 6
    • 77958004840 scopus 로고    scopus 로고
    • The ploidy conveyor of mature hepatocytes as a source of genetic variation
    • Duncan AW, Taylor MH, Hickey RD, Hanlon Newell AE, Lenzi ML, et al: The ploidy conveyor of mature hepatocytes as a source of genetic variation. Nature 467: 707-710 (2010).
    • (2010) Nature , vol.467 , pp. 707-710
    • Duncan, A.W.1    Taylor, M.H.2    Hickey, R.D.3    Hanlon Newell, A.E.4    Lenzi, M.L.5
  • 7
    • 0036286297 scopus 로고    scopus 로고
    • Micronutrients and genomic stability: A new paradigm for recommended dietary allowances (RDAs)
    • DOI 10.1016/S0278-6915(02)00028-5, PII S0278691502000285
    • Fenech M: Micronutrients and genomic stability: A new paradigm for recommended dietary allowances (RDAs). Food Chem Toxicol 40: 1113-1117 (2002). (Pubitemid 34626875)
    • (2002) Food and Chemical Toxicology , vol.40 , Issue.8 , pp. 1113-1117
    • Fenech, M.1
  • 8
    • 78650639748 scopus 로고    scopus 로고
    • The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells-past, present and future
    • Fenech M, Holland N, Zeiger E, Chang WP, Burgaz S, et al: The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells-past, present and future. Mutagenesis 26: 239-245 (2011).
    • (2011) Mutagenesis , vol.26 , pp. 239-245
    • Fenech, M.1    Holland, N.2    Zeiger, E.3    Chang, W.P.4    Burgaz, S.5
  • 9
    • 31144469134 scopus 로고    scopus 로고
    • Structural variation in the human genome
    • DOI 10.1038/nrg1767, PII NRG1767
    • Feuk L, Carson AR, Scherer SW: Structural variation in the human genome. Nat Rev Genet 7: 85-97 (2006). (Pubitemid 43128895)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.2 , pp. 85-97
    • Feuk, L.1    Carson, A.R.2    Scherer, S.W.3
  • 10
    • 0036491860 scopus 로고    scopus 로고
    • Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis
    • DOI 10.1007/s00412-001-0180-2
    • Flagiello D, Bernardino-Sgherri J, Dutrillaux B: Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis. Chromosoma 111: 37-44 (2002). (Pubitemid 41490238)
    • (2002) Chromosoma , vol.111 , Issue.1 , pp. 37-44
    • Flagiello, D.1    Bernardino-Sgherri, J.2    Dutrillaux, B.3
  • 11
    • 79953304054 scopus 로고    scopus 로고
    • Sex reduces genetic variation: A multidisciplinary review
    • Gorelick R, Heng HH: Sex reduces genetic variation: A multidisciplinary review. Evolution 65: 1088-1098 (2011).
    • (2011) Evolution , vol.65 , pp. 1088-1098
    • Gorelick, R.1    Heng, H.H.2
  • 12
    • 0024711822 scopus 로고
    • 5-Azadeoxycytidine induced undercondensation in the giant X chromosomes of Microtus agrestis
    • Haaf T, Schmid M: 5-Azadeoxycytidine induced undercondensation in the giant X chromosomes of Microtus agrestis . Chromosoma 98: 93-98 (1989).
    • (1989) Chromosoma , vol.98 , pp. 93-98
    • Haaf, T.1    Schmid, M.2
  • 13
    • 77950398306 scopus 로고    scopus 로고
    • Human genome at ten: Life is complicated
    • Hayden EC: Human genome at ten: Life is complicated. Nature 464: 3 (2010).
    • (2010) Nature , vol.464 , pp. 3
    • Hayden, E.C.1
  • 14
    • 34547641984 scopus 로고    scopus 로고
    • Cancer genome sequencing: The challenges ahead
    • DOI 10.1002/bies.20610
    • Heng HH: Cancer genome sequencing: The challenges ahead. Bioessays 29: 783-794 (2007a). (Pubitemid 47204283)
    • (2007) BioEssays , vol.29 , Issue.8 , pp. 783-794
    • Heng, H.H.Q.1
  • 15
    • 34547614739 scopus 로고    scopus 로고
    • Elimination of altered karyotypes by sexual reproduction preserves species identity
    • DOI 10.1139/G07-039
    • Heng HH: Elimination of altered karyotypes by sexual reproduction preserves species identity. Genome 50: 517-524 (2007b). (Pubitemid 47236503)
    • (2007) Genome , vol.50 , Issue.5 , pp. 517-524
    • Heng, H.H.Q.1
  • 16
    • 84890314821 scopus 로고    scopus 로고
    • Karyotypic chaos, a form of non-clonal chromosome aberrations, plays a key role for cancer progression and drug resistance
    • Vermont, June
    • Heng HH: Karyotypic chaos, a form of non-clonal chromosome aberrations, plays a key role for cancer progression and drug resistance. FASEB Summer Research Conferences: Nuclear Structure and Cancer Vermont Academy, Saxtons River, Vermont, June 16-21 (2007c).
    • (2007) FASEB Summer Research Conferences: Nuclear Structure and Cancer Vermont Academy, Saxtons River , pp. 16-21
    • Heng, H.H.1
  • 17
    • 66449129067 scopus 로고    scopus 로고
    • The genome-centric concept: Resynthesis of evolutionary theory
    • Heng HH: The genome-centric concept: Resynthesis of evolutionary theory. Bioessays 31: 512-525 (2009).
    • (2009) Bioessays , vol.31 , pp. 512-525
    • Heng, H.H.1
  • 18
    • 77958102017 scopus 로고    scopus 로고
    • Missing heritability and stochastic genome alterations
    • Heng HH: Missing heritability and stochastic genome alterations. Nat Rev Genet 11: 812-812 (2010).
    • (2010) Nat Rev Genet , vol.11 , pp. 812-812
    • Heng, H.H.1
  • 21
    • 0031158307 scopus 로고    scopus 로고
    • From free chromatin analysis to high resolution fiber FISH
    • Heng HH, Shi XM: From free chromatin analysis to high resolution fiber fish. Cell Res 7: 119-124 (1997). (Pubitemid 127528001)
    • (1997) Cell Research , vol.7 , Issue.1 , pp. 119-124
    • Heng, H.Q.H.1    Shi, X.M.2
  • 22
    • 0026667606 scopus 로고
    • High-resolution mapping of mammalian genes by in situ hybridization to free chromatin
    • Heng HH, Squire J, Tsui LC: High-resolution mapping of mammalian genes by in situ hybridization to free chromatin. Proc Natl Acad Sci USA 89: 9509-9513 (1992).
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9509-9513
    • Heng, H.H.1    Squire, J.2    Tsui, L.C.3
  • 25
    • 33745580375 scopus 로고    scopus 로고
    • Clonal and non-clonal chromosome aberrations and genome variation and aberration
    • DOI 10.1139/g06-023
    • Heng HH, Liu G, Bremer S, Ye KJ, Stevens J, Ye CJ: Clonal and non-clonal chromosome aberrations and genome variation and aberration. Genome 49: 195-204 (2006b). (Pubitemid 43979153)
    • (2006) Genome , vol.49 , Issue.3 , pp. 195-204
    • Heng, H.H.Q.1    Liu, G.2    Bremer, S.3    Ye, K.J.4    Stevens, J.5    Ye, C.J.6
  • 27
    • 77957984508 scopus 로고    scopus 로고
    • Genetic and epigenetic heterogeneity in cancer: The ultimate challenge for drug therapy
    • Heng HH, Liu G, Stevens JB, Bremer SW, Ye KJ, Ye CJ: Genetic and epigenetic heterogeneity in cancer: The ultimate challenge for drug therapy. Curr Drug Targets 11: 1304-1316 (2010).
    • (2010) Curr Drug Targets , vol.11 , pp. 1304-1316
    • Heng, H.H.1    Liu, G.2    Stevens, J.B.3    Bremer, S.W.4    Ye, K.J.5    Ye, C.J.6
  • 28
    • 80053006367 scopus 로고    scopus 로고
    • Decoding the genome beyond sequencing: The new phase of genomic research
    • Heng HH, Liu G, Stevens JB, Bremer SW, Ye KJ, et al: Decoding the genome beyond sequencing: The new phase of genomic research. Genomics 98: 242-252 (2011a).
    • (2011) Genomics , vol.98 , pp. 242-252
    • Heng, H.H.1    Liu, G.2    Stevens, J.B.3    Bremer, S.W.4    Ye, K.J.5
  • 30
    • 0344219765 scopus 로고
    • The study of the chromatin and the chromosome structure for Bufo gargarizans by the light microscope
    • Heng HQ, Chen WY: The study of the chromatin and the chromosome structure for Bufo gargarizans by the light microscope. J Sichuan Univ Nat Sci 2: 105-109 (1985).
    • (1985) J Sichuan Univ Nat Sci , vol.2 , pp. 105-109
    • Heng, H.Q.1    Chen, W.Y.2
  • 31
    • 0345513524 scopus 로고
    • Studies of the late G2 chromatin structure and the chromosome formation
    • Heng HQ, Chen WY: Studies of the late G2 chromatin structure and the chromosome formation. Acta Genetica Sinica 14: 237-242 (1987).
    • (1987) Acta Genetica Sinica , vol.14 , pp. 237-242
    • Heng, H.Q.1    Chen, W.Y.2
  • 32
    • 84877584631 scopus 로고
    • The free chromatin structure in blood cell culture
    • Heng HQ, Zhao XL: The free chromatin structure in blood cell culture. J Sichuan Univ Nat Sci 4: 480-485 (1989).
    • (1989) J Sichuan Univ Nat Sci , vol.4 , pp. 480-485
    • Heng, H.Q.1    Zhao, X.L.2
  • 33
    • 84877578901 scopus 로고
    • Studies on amphibian chromosome by the high resolution banding
    • Heng HQ, Chen WY, Yosida TH: Studies on amphibian chromosome by the high resolution banding. Proc Japan Acad 62: 53-56 (1987).
    • (1987) Proc Japan Acad , vol.62 , pp. 53-56
    • Heng, H.Q.1    Chen, W.Y.2    Yosida, T.H.3
  • 34
    • 0041329480 scopus 로고
    • Structure of the chromosome and its formation. II. Studies on the sister unit fibers
    • Heng HQ, Lin R, Zhao XL, Chen WY: Structure of the chromosome and its formation. II. Studies on the sister unit fibers. Nucleus 30: 2-9 (1988a).
    • (1988) Nucleus , vol.30 , pp. 2-9
    • Heng, H.Q.1    Lin, R.2    Zhao, X.L.3    Chen, W.Y.4
  • 35
    • 0023921810 scopus 로고
    • Effects of pingyanymycin on chromosomes: A possible structural basis for chromosome aberration
    • Heng HQ, Chen WY, Wang YC: Effects of pingyanymycin on chromosomes: A possible structural basis for chromosome aberration. Mutat Res 199: 199-205 (1988b).
    • (1988) Mutat Res , vol.199 , pp. 199-205
    • Heng, H.Q.1    Chen, W.Y.2    Wang, Y.C.3
  • 36
    • 84877277146 scopus 로고    scopus 로고
    • Genome constraint through sexual reproduction: Application of 4D-genomics in reproductive biology
    • Epub ahead of print (2013)
    • Horne SD, Abdallah BY, Stevens JB, Liu G, Ye KJ, et al: Genome constraint through sexual reproduction: Application of 4D-Genomics in reproductive biology. Syst Biol Reprod Med, Epub ahead of print (2013).
    • Syst Biol Reprod Med
    • Horne, S.D.1    Abdallah, B.Y.2    Stevens, J.B.3    Liu, G.4    Ye, K.J.5
  • 37
    • 78650653552 scopus 로고    scopus 로고
    • Micronucleus formation detected by live-cell imaging
    • Huang Y, Fenech M, Shi Q: Micronucleus formation detected by live-cell imaging. Mutagenesis 26: 133-138 (2011).
    • (2011) Mutagenesis , vol.26 , pp. 133-138
    • Huang, Y.1    Fenech, M.2    Shi, Q.3
  • 40
    • 0030987115 scopus 로고    scopus 로고
    • Mechanical continuity and reversible chromosome disassembly within intact genomes removed from living cells
    • DOI 10.1002/(SICI)1097-4644(199704)65:1<114::AID-JCB12>3.0.CO;2-K
    • Maniotis AJ, Bojanowski K, Ingber DE: Mechanical continuity and reversible chromosome disassembly within intact genomes removed from living cells. J Cell Biochem 65: 114-130 (1997). (Pubitemid 27188074)
    • (1997) Journal of Cellular Biochemistry , vol.65 , Issue.1 , pp. 114-130
    • Maniotis, A.J.1    Bojanowski, K.2    Ingber, D.E.3
  • 41
    • 0034125650 scopus 로고    scopus 로고
    • Recurrent chromosome aberrations in cancer
    • DOI 10.1016/S1383-5742(00)00006-5, PII S1383574200000065
    • Mitelman F: Recurrent chromosome aberrations in cancer. Mutat Res 462: 247-253 (2000). (Pubitemid 30190232)
    • (2000) Mutation Research - Reviews in Mutation Research , vol.462 , Issue.2-3 , pp. 247-253
    • Mitelman, F.1
  • 42
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell PC: The clonal evolution of tumor cell populations. Science 194: 23-28 (1976).
    • (1976) Science , vol.194 , pp. 23-28
    • Nowell, P.C.1
  • 45
    • 0035818495 scopus 로고    scopus 로고
    • Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocations
    • DOI 10.1073/pnas.241355098
    • Smith L, Plug A, Thayer M: Delayed replication timing leads to delayed mitotic chromosome condensation and chromosomal instability of chromosome translocations. Proc Natl Acad Sci USA 98: 13300-13305 (2001). (Pubitemid 33051357)
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.23 , pp. 13300-13305
    • Smith, L.1    Plug, A.2    Thayer, M.3
  • 46
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, et al: Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144: 27-40 (2011).
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1    Greenman, C.D.2    Fu, B.3    Yang, F.4    Bignell, G.R.5
  • 48
    • 77957888616 scopus 로고    scopus 로고
    • Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation
    • Stevens JB, Abdallah BY, Regan SM, Liu G, Bremer SW, et al: Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation. Mol Cytogenet 3: 20 (2010).
    • (2010) Mol Cytogenet , vol.3 , pp. 20
    • Stevens, J.B.1    Abdallah, B.Y.2    Regan, S.M.3    Liu, G.4    Bremer, S.W.5
  • 49
  • 51
    • 84975742565 scopus 로고    scopus 로고
    • The 1000 genomes project consortium: A map of human genome variation from populationscale sequencing
    • The 1000 Genomes Project Consortium: A map of human genome variation from populationscale sequencing. Nature 467: 1061-1073 (2010).
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 53
    • 80055090025 scopus 로고    scopus 로고
    • Most random gene expression signatures are significantly associated with breast cancer outcome
    • Venet D, Dumont JE, Detours V: Most random gene expression signatures are significantly associated with breast cancer outcome. PLoS Comput Biol 7:e1002240 (2011).
    • (2011) PLoS Comput Biol , vol.7
    • Venet, D.1    Dumont, J.E.2    Detours, V.3
  • 54
    • 0020546228 scopus 로고
    • Sequence of centromere separation: Occurrence, possible significance, and control
    • DOI 10.1016/0165-4608(83)90142-5
    • Vig BK: Sequence of centromere separation: Occurrence, possible significance, and control. Cancer Genet Cytogenet 8: 249-274 (1983). (Pubitemid 13055252)
    • (1983) Cancer Genetics and Cytogenetics , vol.8 , Issue.3 , pp. 249-274
    • Vig, B.K.1
  • 55
    • 0032429051 scopus 로고    scopus 로고
    • Decondensation of pericentric heterochromatin alters the sequence of centromere separation in mouse cells
    • DOI 10.1007/s004120050325
    • Vig BK, Willcourt M: Decondensation of pericentric heterochromatin alters the sequence of centromere separation in mouse cells. Chromosoma 107: 417-423 (1998). (Pubitemid 29057534)
    • (1998) Chromosoma , vol.107 , Issue.6-7 , pp. 417-423
    • Vig, B.K.1    Willcourt, M.2
  • 56
    • 0027401607 scopus 로고
    • The multistep nature of cancer
    • DOI 10.1016/0168-9525(93)90209-Z
    • Vogelstein B, Kinzler KW: The multistep nature of cancer. Trends Genet 9: 138-141 (1993). (Pubitemid 23098782)
    • (1993) Trends in Genetics , vol.9 , Issue.4 , pp. 138-141
    • Vogelstein, B.1    Kinzler, K.W.2
  • 58
    • 61549083373 scopus 로고    scopus 로고
    • The evolution of meiosis from mitosis
    • Wilkins AS, Holliday R: The evolution of meiosis from mitosis. Genetics 181: 3-12 (2009).
    • (2009) Genetics , vol.181 , pp. 3-12
    • Wilkins, A.S.1    Holliday, R.2
  • 60
    • 62149092895 scopus 로고    scopus 로고
    • Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer
    • Ye CJ, Stevens JB, Liu G, Bremer SW, Jaiswal AS, et al: Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer. J Cell Physiol 219: 288-300 (2009).
    • (2009) J Cell Physiol , vol.219 , pp. 288-300
    • Ye, C.J.1    Stevens, J.B.2    Liu, G.3    Bremer, S.W.4    Jaiswal, A.S.5


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