-
1
-
-
58749104364
-
The promises and pitfalls of RNAinterference- based therapeutics
-
D. Castanotto and J. J. Rossi, The promises and pitfalls of RNAinterference- based therapeutics. Nature 457, 426 (2009).
-
(2009)
Nature
, vol.457
, pp. 426
-
-
Castanotto, D.1
Rossi, J.J.2
-
2
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
E. S. Lander, L. M. Linton, B. Birren, C. Nusbaum, M. C. Zody, J. Baldwin, K. Devon, K. Dewar, M. Doyle, W. FitzHugh, R. Funke, D. Gage, K. Harris, A. Heaford, J. Howland, L. Kann, J. Lehoczky, R. LeVine, P. McEwan, K. McKernan, J. Meldrim, J. P. Mesirov, C. Miranda, W. Morris, J. Naylor, C. Raymond, M. Rosetti, R. Santos, A. Sheridan, C. Sougnez, N. Stange- Thomann, N. Stojanovic, A. Subramanian, D. Wyman, J. Rogers, J. Sulston, R. Ainscough, S. Beck, D. Bentley, J. Burton, C. Clee, N. Carter, A. Coulson, R. Deadman, P. Deloukas, A. Dunham, I. Dunham, R. Durbin, L. French, D. Grafham, S. Gregory, T. Hubbard, S. Humphray, A. Hunt, M. Jones, C. Lloyd, A. McMurray, L. Matthews, S. Mercer, S. Milne, J. C. Mullikin, A. Mungall, R. Plumb, M. Ross, R. Shownkeen, S. Sims, R. H. Waterston, R. K. Wilson, L. W. Hillier, J. D. McPherson, M. A. Marra, E. R. Mardis, L. A. Fulton, A. T. Chinwalla, K. H. Pepin, W. R. Gish, S. L. Chissoe, M. C. Wendl, K. D. Delehaunty, T. L. Miner, A. Delehaunty, J. B. Kramer, L. L. Cook, R. S. Fulton, D. L. Johnson, P. J. Minx, S. W. Clifton, T. Hawkins, E. Branscomb, P. Predki, P. Richardson, S. Wenning, T. Slezak, N. Doggett, J. F. Cheng, A. Olsen, S. Lucas, C. Elkin, E. Uberbacher, M. Frazier, R. A. Gibbs, D. M. Muzny, S. E. Scherer, J. B. Bouck, E. J. Sodergren, K. C. Worley, C. M. Rives, J. H. Gorrell, M. L. Metzker, S. L. Naylor, R. S. Kucherlapati, D. L. Nelson, G. M. Weinstock, Y. Sakaki, A. Fujiyama, M. Hattori, T. Yada, A. Toyoda, T. Itoh, C. Kawagoe, H. Watanabe, Y. Totoki, T. Taylor, J. Weissenbach, R. Heilig, W. Saurin, F. Artiguenave, P. Brottier, T. Bruls, E. Pelletier, C. Robert, P. Wincker, D. R. Smith, L. Doucette-Stamm, M. Rubenfield, K. Weinstock, H. M. Lee, J. Dubois, A. Rosenthal, M. Platzer, G. Nyakatura, S. Taudien, A. Rump, H. Yang, J. Yu, J. Wang, G. Huang, J. Gu, L. Hood, L. Rowen, A. Madan, S. Qin, R. W. Davis, N. A. Federspiel, A. P. Abola, M. J. Proctor, R. M. Myers, J. Schmutz, M. Dickson, J. Grimwood, D. R. Cox, M. V. Olson, R. Kaul, N. Shimizu, K. Kawasaki, S. Minoshima, G. A. Evans, M. Athanasiou, R. Schultz, B. A. Roe, F. Chen, H. Pan, J. Ramser, H. Lehrach, R. Reinhardt, W. R. McCombie, M. de la Bastide, N. Dedhia, H. Blocker, K. Hornischer, G. Nordsiek, R. Agarwala, L. Aravind, J. A. Bailey, A. Bateman, S. Batzoglou, E. Birney, P. Bork, D. G. Brown, C. B. Burge, L. Cerutti, H. C. Chen, D. Church, M. Clamp, R. R. Copley, T. Doerks, S. R. Eddy, E. E. Eichler, T. S. Furey, J. Galagan, J. G. Gilbert, C. Harmon, Y. Hayashizaki, D. Haussler, H. Hermjakob, K. Hokamp, W. Jang, L. S. Johnson, T. A. Jones, S. Kasif, A. Kaspryzk, S. Kennedy, W. J. Kent, P. Kitts, E. V. Koonin, I. Korf, D. Kulp, D. Lancet, T. M. Lowe, A. McLysaght, T. Mikkelsen, J. V. Moran, N. Mulder, V. J. Pollara, C. P. Ponting, G. Schuler, J. Schultz, G. Slater, A. F. Smit, E. Stupka, J. Szustakowski, D. Thierry-Mieg, J. Thierry-Mieg, L. Wagner, J. Wallis, R. Wheeler, A. Williams, Y. I. Wolf, K. H. Wolfe, S. P. Yang, R. F. Yeh, F. Collins, M. S. Guyer, J. Peterson, A. Felsenfeld, K. A. Wetterstrand, A. Patrinos, M. J. Morgan, P. de Jong, J. J. Catanese, K. Osoegawa, H. Shizuya, S. Choi, and Y. J. Chen, Initial sequencing and analysis of the human genome. Nature 409, 860 (2001).
-
(2001)
Nature
, vol.409
, pp. 860
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
Devon, K.7
Dewar, K.8
Doyle, M.9
FitzHugh, W.10
Funke, R.11
Gage, D.12
Harris, K.13
Heaford, A.14
Howland, J.15
Kann, L.16
Lehoczky, J.17
LeVine, R.18
McEwan, P.19
McKernan, K.20
Meldrim, J.21
Mesirov, J.P.22
Miranda, C.23
Morris, W.24
Naylor, J.25
Raymond, C.26
Rosetti, M.27
Santos, R.28
Sheridan, A.29
Sougnez, C.30
Stange- Thomann, N.31
Stojanovic, N.32
Subramanian, A.33
Wyman, D.34
Rogers, J.35
Sulston, J.36
Ainscough, R.37
Beck, S.38
Bentley, D.39
Burton, J.40
Clee, C.41
Carter, N.42
Coulson, A.43
Deadman, R.44
Deloukas, P.45
Dunham, A.46
Dunham, I.47
Durbin, R.48
French, L.49
Grafham, D.50
Gregory, S.51
Hubbard, T.52
Humphray, S.53
Hunt, A.54
Jones, M.55
Lloyd, C.56
McMurray, A.57
Matthews, L.58
Mercer, S.59
Milne, S.60
Mullikin, J.C.61
Mungall, A.62
Plumb, R.63
Ross, M.64
Shownkeen, R.65
Sims, S.66
Waterston, R.H.67
Wilson, R.K.68
Hillier, L.W.69
McPherson, J.D.70
Marra, M.A.71
Mardis, E.R.72
Fulton, L.A.73
Chinwalla, A.T.74
Pepin, K.H.75
Gish, W.R.76
Chissoe, S.L.77
Wendl, M.C.78
Delehaunty, K.D.79
Miner, T.L.80
Delehaunty, A.81
Kramer, J.B.82
Cook, L.L.83
Fulton, R.S.84
Johnson, D.L.85
Minx, P.J.86
Clifton, S.W.87
Hawkins, T.88
Branscomb, E.89
Predki, P.90
Richardson, P.91
Wenning, S.92
Slezak, T.93
Doggett, N.94
Cheng, J.F.95
Olsen, A.96
Lucas, S.97
Elkin, C.98
Uberbacher, E.99
more..
-
4
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
A. Fire, S. Xu, M. K. Montgomery, S. A. Kostas, S. E. Driver, and C. C. Mello, Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806 (1998).
-
(1998)
Nature
, vol.391
, pp. 806
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
5
-
-
4644350944
-
Unlocking the potential of the human genome with RNA interference
-
G. J. Hannon and J. J. Rossi, Unlocking the potential of the human genome with RNA interference. Nature 431, 371 (2004).
-
(2004)
Nature
, vol.431
, pp. 371
-
-
Hannon, G.J.1
Rossi, J.J.2
-
6
-
-
18344369543
-
MicroRNA biogenesis: Coordinated cropping and dicing
-
V. N. Kim, MicroRNA biogenesis: Coordinated cropping and dicing. Nat. Rev. Mol. Cell Biol. 6, 376 (2005).
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 376
-
-
Kim, V.N.1
-
7
-
-
20944450160
-
Combinatorial microRNA target predictions
-
A. Krek, D. Grun, M. N. Poy, R. Wolf, L. Rosenberg, E. J. Epstein, P. MacMenamin, I. da Piedade, K. C. Gunsalus, M. Stoffel, and N. Rajewsky, Combinatorial microRNA target predictions. Nat. Genet. 37, 495 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 495
-
-
Krek, A.1
Grun, D.2
Poy, M.N.3
Wolf, R.4
Rosenberg, L.5
Epstein, E.J.6
MacMenamin, P.7
Da Piedade, I.8
Gunsalus, K.C.9
Stoffel, M.10
Rajewsky, N.11
-
8
-
-
26944498261
-
Approaches for chemically synthesized siRNA and vector-mediated RNAi
-
M. Amarzguioui, J. J. Rossi, and D. Kim, Approaches for chemically synthesized siRNA and vector-mediated RNAi. FEBS Lett. 579, 5974 (2005).
-
(2005)
FEBS Lett.
, vol.579
, pp. 5974
-
-
Amarzguioui, M.1
Rossi, J.J.2
Kim, D.3
-
9
-
-
34447559636
-
Interfering with disease: A progress report on siRNA-based therapeutics
-
A. de Fougerolles, H. P. Vornlocher, J. Maraganore, and J. Lieberman, Interfering with disease: A progress report on siRNA-based therapeutics. Nat. Rev. Drug Discov. 6, 443 (2007).
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 443
-
-
De Fougerolles, A.1
Vornlocher, H.P.2
Maraganore, J.3
Lieberman, J.4
-
10
-
-
79954580272
-
Current prospects for RNA interference-based therapies
-
B. L. Davidson and P. B. McCray, Jr., Current prospects for RNA interference-based therapies. Nat. Rev. Genet. 12, 329 (2011).
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 329
-
-
Davidson, B.L.1
McCray Jr., P.B.2
-
11
-
-
61849162695
-
siRNA conjugate delivery systems
-
J. H. Jeong, H. Mok, Y. K. Oh, and T. G. Park, siRNA conjugate delivery systems. Bioconjug. Chem. 20, 5 (2009).
-
(2009)
Bioconjug. Chem.
, vol.20
, pp. 5
-
-
Jeong, J.H.1
Mok, H.2
Oh, Y.K.3
Park, T.G.4
-
12
-
-
34548644167
-
Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life
-
A. Sato, S. W. Choi, M. Hirai, A. Yamayoshi, R. Moriyama, T. Yamano, M. Takagi, A. Kano, A. Shimamoto, and A. Maruyama, Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life. J. Control. Release 122, 209 (2007).
-
(2007)
J. Control. Release
, vol.122
, pp. 209
-
-
Sato, A.1
Choi, S.W.2
Hirai, M.3
Yamayoshi, A.4
Moriyama, R.5
Yamano, T.6
Takagi, M.7
Kano, A.8
Shimamoto, A.9
Maruyama, A.10
-
13
-
-
84859269808
-
Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design
-
K. Buyens, S. C. De Smedt, K. Braeckmans, J. Demeester, L. Peeters, L. A. van Grunsven, X. de Mollerat du Jeu, R. Sawant, V. Torchilin, K. Farkasova, M. Ogris, and N. N. Sanders, Liposome based systems for systemic siRNA delivery: Stability in blood sets the requirements for optimal carrier design. J. Control. Release 158, 362 (2012).
-
(2012)
J. Control. Release
, vol.158
, pp. 362
-
-
Buyens, K.1
De Smedt, S.C.2
Braeckmans, K.3
Demeester, J.4
Peeters, L.5
Van Grunsven, L.A.6
De Mollerat Du Jeu, X.7
Sawant, R.8
Torchilin, V.9
Farkasova, K.10
Ogris, M.11
Sanders, N.N.12
-
14
-
-
84881525823
-
Optimized siRNA-PEG conjugates for extended blood circulation and reduced urine excretion in mice
-
F. Iversen, C. Yang, F. Dagnaes-Hansen, D. H. Schaffert, J. Kjems, and S. Gao, Optimized siRNA-PEG conjugates for extended blood circulation and reduced urine excretion in mice. Theranostics 3, 201 (2013).
-
(2013)
Theranostics
, vol.3
, pp. 201
-
-
Iversen, F.1
Yang, C.2
Dagnaes-Hansen, F.3
Schaffert, D.H.4
Kjems, J.5
Gao, S.6
-
15
-
-
84877301967
-
Multifunctional hierarchically assembled nanostructures as complex stage-wise dual-delivery systems for coincidental yet differential trafficking of siRNA and paclitaxel
-
M. Elsabahy, R. Shrestha, C. Clark, S. Taylor, J. Leonard, and K. L. Wooley, Multifunctional hierarchically assembled nanostructures as complex stage-wise dual-delivery systems for coincidental yet differential trafficking of siRNA and paclitaxel. Nano Lett. 13, 2172 (2013).
-
(2013)
Nano Lett.
, vol.13
, pp. 2172
-
-
Elsabahy, M.1
Shrestha, R.2
Clark, C.3
Taylor, S.4
Leonard, J.5
Wooley, K.L.6
-
16
-
-
84876083926
-
pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells
-
D. W. Dong, B. Xiang, W. Gao, Z. Z. Yang, J. Q. Li, and X. R. Qi, pH-responsive complexes using prefunctionalized polymers for synchronous delivery of doxorubicin and siRNA to cancer cells. Biomaterials 34, 4849 (2013).
-
(2013)
Biomaterials
, vol.34
, pp. 4849
-
-
Dong, D.W.1
Xiang, B.2
Gao, W.3
Yang, Z.Z.4
Li, J.Q.5
Qi, X.R.6
-
17
-
-
51049092308
-
Factors affecting the clearance and biodistribution of polymeric nanoparticles
-
F. Alexis, E. Pridgen, L. K. Molnar, and O. C. Farokhzad, Factors affecting the clearance and biodistribution of polymeric nanoparticles. Mol. Pharm. 5, 505 (2008).
-
(2008)
Mol. Pharm.
, vol.5
, pp. 505
-
-
Alexis, F.1
Pridgen, E.2
Molnar, L.K.3
Farokhzad, O.C.4
-
18
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
J. Soutschek, A. Akinc, B. Bramlage, K. Charisse, R. Constien, M. Donoghue, S. Elbashir, A. Geick, P. Hadwiger, J. Harborth, M. John, V. Kesavan, G. Lavine, R. K. Pandey, T. Racie, K. G. Rajeev, I. Rohl, I. Toudjarska, G. Wang, S. Wuschko, D. Bumcrot, V. Koteliansky, S. Limmer, M. Manoharan, and H. P. Vornlocher, Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432, 173 (2004).
-
(2004)
Nature
, vol.432
, pp. 173
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Geick, A.8
Hadwiger, P.9
Harborth, J.10
John, M.11
Kesavan, V.12
Lavine, G.13
Pandey, R.K.14
Racie, T.15
Rajeev, K.G.16
Rohl, I.17
Toudjarska, I.18
Wang, G.19
Wuschko, S.20
Bumcrot, D.21
Koteliansky, V.22
Limmer, S.23
Manoharan, M.24
Vornlocher, H.P.25
more..
-
19
-
-
67649120076
-
Overcoming obstacles to develop effective and safe siRNA therapeutics
-
L. Li and Y. Shen, Overcoming obstacles to develop effective and safe siRNA therapeutics. Expert Opin. Biol. Ther. 9, 609 (2009).
-
(2009)
Expert Opin. Biol. Ther.
, vol.9
, pp. 609
-
-
Li, L.1
Shen, Y.2
-
21
-
-
14344260029
-
Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid
-
S. C. Semple, T. O. Harasym, K. A. Clow, S. M. Ansell, S. K. Klimuk, and M. J. Hope, Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid. J. Pharmacol. Exp. Ther. 312, 1020 (2005).
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, pp. 1020
-
-
Semple, S.C.1
Harasym, T.O.2
Clow, K.A.3
Ansell, S.M.4
Klimuk, S.K.5
Hope, M.J.6
-
22
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Y. Matsumura and H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 46, 6387 (1986).
-
(1986)
Cancer Res.
, vol.46
, pp. 6387
-
-
Matsumura, Y.1
Maeda, H.2
-
23
-
-
33746172167
-
Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
-
D. B. Kirpotin, D. C. Drummond, Y. Shao, M. R. Shalaby, K. Hong, U. B. Nielsen, J. D. Marks, C. C. Benz, and J. W. Park, Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res. 66, 6732 (2006).
-
(2006)
Cancer Res.
, vol.66
, pp. 6732
-
-
Kirpotin, D.B.1
Drummond, D.C.2
Shao, Y.3
Shalaby, M.R.4
Hong, K.5
Nielsen, U.B.6
Marks, J.D.7
Benz, C.C.8
Park, J.W.9
-
24
-
-
0028535425
-
Gene transfer with a series of lipophilic DNA-binding molecules
-
J. S. Remy, C. Sirlin, P. Vierling, and J. P. Behr, Gene transfer with a series of lipophilic DNA-binding molecules. Bioconjug. Chem. 5, 647 (1994).
-
(1994)
Bioconjug. Chem.
, vol.5
, pp. 647
-
-
Remy, J.S.1
Sirlin, C.2
Vierling, P.3
Behr, J.P.4
-
25
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
O. Boussif, F. Lezoualc'h, M. A. Zanta, M. D. Mergny, D. Scherman, B. Demeneix, and J. P. Behr, A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine. Proc. Natl. Acad. Sci. U.S.A. 92, 7297 (1995).
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 7297
-
-
Boussif, O.1
Lezoualc'H, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Behr, J.P.7
-
26
-
-
77951168054
-
Breaking down the barriers: SiRNA delivery and endosome escape
-
M. Dominska and D. M. Dykxhoorn, Breaking down the barriers: siRNA delivery and endosome escape. J. Cell Sci. 123, 1183 (2010).
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1183
-
-
Dominska, M.1
Dykxhoorn, D.M.2
-
27
-
-
0025042733
-
Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA
-
R. A. Parente, S. Nir, and F. C. Szoka, Jr., Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry 29, 8720 (1990).
-
(1990)
Biochemistry
, vol.29
, pp. 8720
-
-
Parente, R.A.1
Nir, S.2
Szoka Jr., F.C.3
-
28
-
-
2942754299
-
Molecular mechanism of Peptide-induced pores in membranes
-
H. W. Huang, F. Y. Chen, and M. T. Lee, Molecular mechanism of Peptide-induced pores in membranes. Phys. Rev. Lett. 92, 198304 (2004).
-
(2004)
Phys. Rev. Lett.
, vol.92
, pp. 198304
-
-
Huang, H.W.1
Chen, F.Y.2
Lee, M.T.3
-
29
-
-
77957569447
-
Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes
-
M. Thibault, S. Nimesh, M. Lavertu, and M. D. Buschmann, Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes. Mol. Ther. 18, 1787 (2010).
-
(2010)
Mol. Ther.
, vol.18
, pp. 1787
-
-
Thibault, M.1
Nimesh, S.2
Lavertu, M.3
Buschmann, M.D.4
-
30
-
-
70649107800
-
Molecular design of chitosan gene delivery systems with an optimized balance between polyplex stability and polyplex unpacking
-
S. P. Strand, S. Lelu, N. K. Reitan, C. de Lange Davies, P. Artursson, and K. M. Varum, Molecular design of chitosan gene delivery systems with an optimized balance between polyplex stability and polyplex unpacking. Biomaterials 31, 975 (2010).
-
(2010)
Biomaterials
, vol.31
, pp. 975
-
-
Strand, S.P.1
Lelu, S.2
Reitan, N.K.3
De Lange Davies, C.4
Artursson, P.5
Varum, K.M.6
-
31
-
-
65549120153
-
Acetylation of PAMAM dendrimers for cellular delivery of siRNA
-
C. L. Waite, S. M. Sparks, K. E. Uhrich, and C. M. Roth, Acetylation of PAMAM dendrimers for cellular delivery of siRNA. BMC Biotechnol. 9, 38 (2009).
-
(2009)
BMC Biotechnol.
, vol.9
, pp. 38
-
-
Waite, C.L.1
Sparks, S.M.2
Uhrich, K.E.3
Roth, C.M.4
-
32
-
-
0030463150
-
Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: Their role in protein degradation
-
T. E. Tjelle, A. Brech, L. K. Juvet, G. Griffiths, and T. Berg, Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: Their role in protein degradation. J. Cell Sci. 109, 2905 (1996).
-
(1996)
J. Cell Sci.
, vol.109
, pp. 2905
-
-
Tjelle, T.E.1
Brech, A.2
Juvet, L.K.3
Griffiths, G.4
Berg, T.5
-
33
-
-
67349242729
-
Delivery of RNA interference therapeutics using polycation-based nanoparticles
-
K. A. Howard, Delivery of RNA interference therapeutics using polycation-based nanoparticles. Adv. Drug. Deliv. Rev. 61, 710 (2009).
-
(2009)
Adv. Drug. Deliv. Rev.
, vol.61
, pp. 710
-
-
Howard, K.A.1
-
34
-
-
84867642276
-
RNAi-based nanomedicines for targeted personalized therapy
-
A. Daka and D. Peer, RNAi-based nanomedicines for targeted personalized therapy. Adv. Drug. Deliv. Rev. 64, 1508 (2012).
-
(2012)
Adv. Drug. Deliv. Rev.
, vol.64
, pp. 1508
-
-
Daka, A.1
Peer, D.2
-
35
-
-
79551690025
-
Chitosan and its derivatives for gene delivery
-
N. Saranya, A. Moorthi, S. Saravanan, M. P. Devi, and N. Selvamurugan, Chitosan and its derivatives for gene delivery. Int. J. Biol. Macromol. 48, 234 (2011).
-
(2011)
Int. J. Biol. Macromol.
, vol.48
, pp. 234
-
-
Saranya, N.1
Moorthi, A.2
Saravanan, S.3
Devi, M.P.4
Selvamurugan, N.5
-
36
-
-
5444267326
-
Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers
-
M. Koping-Hoggard, K. M. Varum, M. Issa, S. Danielsen, B. E. Christensen, B. T. Stokke, and P. Artursson, Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers. Gene. Ther. 11, 1441 (2004).
-
(2004)
Gene. Ther.
, vol.11
, pp. 1441
-
-
Koping-Hoggard, M.1
Varum, K.M.2
Issa, M.3
Danielsen, S.4
Christensen, B.E.5
Stokke, B.T.6
Artursson, P.7
-
37
-
-
33745077164
-
High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation
-
M. Lavertu, S. Methot, N. Tran-Khanh, and M. D. Buschmann, High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. Biomaterials 27, 4815 (2006).
-
(2006)
Biomaterials
, vol.27
, pp. 4815
-
-
Lavertu, M.1
Methot, S.2
Tran-Khanh, N.3
Buschmann, M.D.4
-
38
-
-
34548630860
-
Chitosan nanoparticles for oral drug and gene delivery
-
K. Bowman and K. W. Leong, Chitosan nanoparticles for oral drug and gene delivery. Int. J. Nanomedicine 1, 117 (2006).
-
(2006)
Int. J. Nanomedicine
, vol.1
, pp. 117
-
-
Bowman, K.1
Leong, K.W.2
-
39
-
-
77956871233
-
Chitosan as a carrier for targeted delivery of small interfering RNA
-
W. E. Rudzinski and T. M. Aminabhavi, Chitosan as a carrier for targeted delivery of small interfering RNA. Int. J. Pharm. 399, 1 (2010).
-
(2010)
Int. J. Pharm.
, vol.399
, pp. 1
-
-
Rudzinski, W.E.1
Aminabhavi, T.M.2
-
40
-
-
77949270747
-
New core-shell nanoparticules for the intravenous delivery of siRNA to experimental thyroid papillary carcinoma
-
H. de Martimprey, J. R. Bertrand, C. Malvy, P. Couvreur, and C. Vauthier, New core-shell nanoparticules for the intravenous delivery of siRNA to experimental thyroid papillary carcinoma. Pharm. Res. 27, 498 (2010).
-
(2010)
Pharm. Res.
, vol.27
, pp. 498
-
-
De Martimprey, H.1
Bertrand, J.R.2
Malvy, C.3
Couvreur, P.4
Vauthier, C.5
-
41
-
-
77952668878
-
Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice
-
M. S. Huh, S. Y. Lee, S. Park, S. Lee, H. Chung, Y. Choi, Y. K. Oh, J. H. Park, S. Y. Jeong, K. Choi, K. Kim, and I. C. Kwon, Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice. J. Control. Release 144, 134 (2010).
-
(2010)
J. Control. Release
, vol.144
, pp. 134
-
-
Huh, M.S.1
Lee, S.Y.2
Park, S.3
Lee, S.4
Chung, H.5
Choi, Y.6
Oh, Y.K.7
Park, J.H.8
Jeong, S.Y.9
Choi, K.10
Kim, K.11
Kwon, I.C.12
-
42
-
-
79955504557
-
Chitosan hydrogel for localized gene silencing
-
H. D. Han, E. M. Mora, J. W. Roh, M. Nishimura, S. J. Lee, R. L. Stone, M. Bar-Eli, G. Lopez-Berestein, and A. K. Sood, Chitosan hydrogel for localized gene silencing. Cancer Biol. Ther. 11, 839 (2011).
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 839
-
-
Han, H.D.1
Mora, E.M.2
Roh, J.W.3
Nishimura, M.4
Lee, S.J.5
Stone, R.L.6
Bar-Eli, M.7
Lopez-Berestein, G.8
Sood, A.K.9
-
43
-
-
84857198814
-
Local delivery of chitosan/VEGF siRNA nanoplexes reduces angiogenesis and growth of breast cancer in vivo
-
E. Salva, L. Kabasakal, F. Eren, N. Ozkan, F. Cakalagaoglu, and J. Akbuga, Local delivery of chitosan/VEGF siRNA nanoplexes reduces angiogenesis and growth of breast cancer in vivo. Nucleic Acid Ther. 22, 40 (2012).
-
(2012)
Nucleic Acid Ther.
, vol.22
, pp. 40
-
-
Salva, E.1
Kabasakal, L.2
Eren, F.3
Ozkan, N.4
Cakalagaoglu, F.5
Akbuga, J.6
-
44
-
-
75149133614
-
Chitosan-based formulations for delivery of DNA and siRNA
-
S. Mao, W. Sun, and T. Kissel, Chitosan-based formulations for delivery of DNA and siRNA. Adv. Drug. Deliv. Rev. 62, 12 (2010).
-
(2010)
Adv. Drug. Deliv. Rev.
, vol.62
, pp. 12
-
-
Mao, S.1
Sun, W.2
Kissel, T.3
-
45
-
-
33749844509
-
Development and characterisation of chitosan nanoparticles for siRNA delivery
-
H. Katas and H. O. Alpar, Development and characterisation of chitosan nanoparticles for siRNA delivery. J. Control. Release 115, 216 (2006).
-
(2006)
J. Control. Release
, vol.115
, pp. 216
-
-
Katas, H.1
Alpar, H.O.2
-
46
-
-
13844265668
-
Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery
-
H. S. Yoo, J. E. Lee, H. Chung, I. C. Kwon, and S. Y. Jeong, Self-assembled nanoparticles containing hydrophobically modified glycol chitosan for gene delivery. J. Control. Release 103, 235 (2005).
-
(2005)
J. Control. Release
, vol.103
, pp. 235
-
-
Yoo, H.S.1
Lee, J.E.2
Chung, H.3
Kwon, I.C.4
Jeong, S.Y.5
-
47
-
-
33845404677
-
Thiolated chitosan/DNA nanocomplexes exhibit enhanced and sustained gene delivery
-
D. Lee, W. Zhang, S. A. Shirley, X. Kong, G. R. Hellermann, R. F. Lockey, and S. S. Mohapatra, Thiolated chitosan/DNA nanocomplexes exhibit enhanced and sustained gene delivery. Pharm. Res. 24, 157 (2007).
-
(2007)
Pharm. Res.
, vol.24
, pp. 157
-
-
Lee, D.1
Zhang, W.2
Shirley, S.A.3
Kong, X.4
Hellermann, G.R.5
Lockey, R.F.6
Mohapatra, S.S.7
-
48
-
-
33646349221
-
A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: Properties and in vitro transfection studies
-
F. Q. Hu, M. D. Zhao, H. Yuan, J. You, Y. Z. Du, and S. Zeng, A novel chitosan oligosaccharide-stearic acid micelles for gene delivery: Properties and in vitro transfection studies. Int. J. Pharm. 315, 158 (2006).
-
(2006)
Int. J. Pharm.
, vol.315
, pp. 158
-
-
Hu, F.Q.1
Zhao, M.D.2
Yuan, H.3
You, J.4
Du, Y.Z.5
Zeng, S.6
-
49
-
-
34247165838
-
A novel PEGylation of chitosan nanoparticles for gene delivery
-
Y. Zhang, J. Chen, Y. Pan, J. Zhao, L. Ren, M. Liao, Z. Hu, L. Kong, and J. Wang, A novel PEGylation of chitosan nanoparticles for gene delivery. Biotechnol. Appl. Biochem. 46, 197 (2007).
-
(2007)
Biotechnol. Appl. Biochem.
, vol.46
, pp. 197
-
-
Zhang, Y.1
Chen, J.2
Pan, Y.3
Zhao, J.4
Ren, L.5
Liao, M.6
Hu, Z.7
Kong, L.8
Wang, J.9
-
50
-
-
31544461289
-
PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo
-
K. Wong, G. Sun, X. Zhang, H. Dai, Y. Liu, C. He, and K. W. Leong, PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. Bioconjug. Chem. 17, 152 (2006).
-
(2006)
Bioconjug. Chem.
, vol.17
, pp. 152
-
-
Wong, K.1
Sun, G.2
Zhang, X.3
Dai, H.4
Liu, Y.5
He, C.6
Leong, K.W.7
-
51
-
-
33846169452
-
Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: Safety and efficacy in xenografted aggressive breast cancer
-
J. Y. Pille, H. Li, E. Blot, J. R. Bertrand, L. L. Pritchard, P. Opolon, A. Maksimenko, H. Lu, J. P. Vannier, J. Soria, C. Malvy, and C. Soria, Intravenous delivery of anti-RhoA small interfering RNA loaded in nanoparticles of chitosan in mice: Safety and efficacy in xenografted aggressive breast cancer. Hum. Gene. Ther. 17, 1019 (2006).
-
(2006)
Hum. Gene. Ther.
, vol.17
, pp. 1019
-
-
Pille, J.Y.1
Li, H.2
Blot, E.3
Bertrand, J.R.4
Pritchard, L.L.5
Opolon, P.6
Maksimenko, A.7
Lu, H.8
Vannier, J.P.9
Soria, J.10
Malvy, C.11
Soria, C.12
-
52
-
-
84873475106
-
Improvement of therapeutic efficacy of PLGA nanoformulation of siRNA targeting anti-apoptotic Bcl-2 through chitosan coating
-
H. V. Jagani, V. R. Josyula, V. R. Palanimuthu, R. C. Hariharapura, and S. S. Gang, Improvement of therapeutic efficacy of PLGA nanoformulation of siRNA targeting anti-apoptotic Bcl-2 through chitosan coating. Eur. J. Pharm. Sci. 48, 611 (2013).
-
(2013)
Eur. J. Pharm. Sci.
, vol.48
, pp. 611
-
-
Jagani, H.V.1
Josyula, V.R.2
Palanimuthu, V.R.3
Hariharapura, R.C.4
Gang, S.S.5
-
53
-
-
10444279209
-
Cyclodextrin-based pharmaceutics: Past, present and future
-
M. E. Davis and M. E. Brewster, Cyclodextrin-based pharmaceutics: Past, present and future. Nat. Rev. Drug Discov. 3, 1023 (2004).
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 1023
-
-
Davis, M.E.1
Brewster, M.E.2
-
54
-
-
0033231242
-
New class of polymers for the delivery of macromolecular therapeutics
-
H. Gonzalez, S. J. Hwang, and M. E. Davis, New class of polymers for the delivery of macromolecular therapeutics. Bioconjug. Chem. 10, 1068 (1999).
-
(1999)
Bioconjug. Chem.
, vol.10
, pp. 1068
-
-
Gonzalez, H.1
Hwang, S.J.2
Davis, M.E.3
-
56
-
-
3242812056
-
Cyclodextrin-modified polyethylenimine polymers for gene delivery
-
S. H. Pun, N. C. Bellocq, A. Liu, G. Jensen, T. Machemer, E. Quijano, T. Schluep, S. Wen, H. Engler, J. Heidel, and M. E. Davis, Cyclodextrin-modified polyethylenimine polymers for gene delivery. Bioconjug. Chem. 15, 831 (2004).
-
(2004)
Bioconjug. Chem.
, vol.15
, pp. 831
-
-
Pun, S.H.1
Bellocq, N.C.2
Liu, A.3
Jensen, G.4
Machemer, T.5
Quijano, E.6
Schluep, T.7
Wen, S.8
Engler, H.9
Heidel, J.10
Davis, M.E.11
-
57
-
-
0037347198
-
In vitro and in vivo gene transfer by an optimized alpha-cyclodextrin conjugate with polyamidoamine dendrimer
-
F. Kihara, H. Arima, T. Tsutsumi, F. Hirayama, and K. Uekama, In vitro and in vivo gene transfer by an optimized alpha-cyclodextrin conjugate with polyamidoamine dendrimer. Bioconjug. Chem. 14, 342 (2003).
-
(2003)
Bioconjug. Chem.
, vol.14
, pp. 342
-
-
Kihara, F.1
Arima, H.2
Tsutsumi, T.3
Hirayama, F.4
Uekama, K.5
-
58
-
-
84865955791
-
Folate-PEG-appended dendrimer conjugate with alpha-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier
-
H. Arima, A. Yoshimatsu, H. Ikeda, A. Ohyama, K. Motoyama, T. Higashi, A. Tsuchiya, T. Niidome, Y. Katayama, K. Hattori, and T. Takeuchi, Folate-PEG-appended dendrimer conjugate with alpha-cyclodextrin as a novel cancer cell-selective siRNA delivery carrier. Mol. Pharm. 9, 2591 (2012).
-
(2012)
Mol. Pharm.
, vol.9
, pp. 2591
-
-
Arima, H.1
Yoshimatsu, A.2
Ikeda, H.3
Ohyama, A.4
Motoyama, K.5
Higashi, T.6
Tsuchiya, A.7
Niidome, T.8
Katayama, Y.9
Hattori, K.10
Takeuchi, T.11
-
59
-
-
77950350157
-
Polysaccharide-modified synthetic polymeric biomaterials
-
A. D. Baldwin and K. L. Kiick, Polysaccharide-modified synthetic polymeric biomaterials. Biopolymers 94, 128 (2010).
-
(2010)
Biopolymers
, vol.94
, pp. 128
-
-
Baldwin, A.D.1
Kiick, K.L.2
-
60
-
-
0034601881
-
Dextrans for targeted and sustained delivery of therapeutic and imaging agents
-
R. Mehvar, Dextrans for targeted and sustained delivery of therapeutic and imaging agents. J. Control. Release 69, 1 (2000).
-
(2000)
J. Control. Release
, vol.69
, pp. 1
-
-
Mehvar, R.1
-
61
-
-
84866679606
-
Conjugation chemistry through acetals toward a dextran-based delivery system for controlled release of siRNA
-
L. Cui, J. L. Cohen, C. K. Chu, P. R. Wich, P. H. Kierstead, and J. M. Frechet, Conjugation chemistry through acetals toward a dextran-based delivery system for controlled release of siRNA. J. Am. Chem. Soc. 134, 15840 (2012).
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 15840
-
-
Cui, L.1
Cohen, J.L.2
Chu, C.K.3
Wich, P.R.4
Kierstead, P.H.5
Frechet, J.M.6
-
62
-
-
0024282306
-
Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro
-
G. Y. Wu and C. H. Wu, Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro. Biochemistry 27, 887 (1988).
-
(1988)
Biochemistry
, vol.27
, pp. 887
-
-
Wu, G.Y.1
Wu, C.H.2
-
63
-
-
0031566270
-
Gene transfer mediated by polyarginine requires a formation of big carriercomplex of DNA aggregate
-
N. Emi, S. Kidoaki, K. Yoshikawa, and H. Saito, Gene transfer mediated by polyarginine requires a formation of big carriercomplex of DNA aggregate. Biochem. Biophys. Res. Commun. 231, 421 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.231
, pp. 421
-
-
Emi, N.1
Kidoaki, S.2
Yoshikawa, K.3
Saito, H.4
-
64
-
-
84862080242
-
Quantitative comparison between poly(L-arginine) and poly(Llysine) at each step of polyplex-based gene transfection using a microinjection technique
-
T. K. T. Hashimoto, T. Nagasaki, A. Murakami, and T. Yamaoka, Quantitative comparison between poly(L-arginine) and poly(Llysine) at each step of polyplex-based gene transfection using a microinjection technique. Sci. Technol. Adv. Mater. 13, 9 (2012).
-
(2012)
Sci. Technol. Adv. Mater.
, vol.13
, pp. 9
-
-
Hashimoto, T.K.T.1
Nagasaki, T.2
Murakami, A.3
Yamaoka, T.4
-
66
-
-
84864022954
-
Self-assembly nanomicelles based on cationic mPEGPLA- b-Polyarginine(R15) triblock copolymer for siRNA delivery
-
Z. X. Zhao, S. Y. Gao, J. C. Wang, C. J. Chen, E. Y. Zhao, W. J. Hou, Q. Feng, L. Y. Gao, X. Y. Liu, L. R. Zhang, and Q. Zhang, Self-assembly nanomicelles based on cationic mPEGPLA- b-Polyarginine(R15) triblock copolymer for siRNA delivery. Biomaterials 33, 6793 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 6793
-
-
Zhao, Z.X.1
Gao, S.Y.2
Wang, J.C.3
Chen, C.J.4
Zhao, E.Y.5
Hou, W.J.6
Feng, Q.7
Gao, L.Y.8
Liu, X.Y.9
Zhang, L.R.10
Zhang, Q.11
-
67
-
-
84862808533
-
A mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA delivery
-
P. Liu, H. Yu, Y. Sun, M. Zhu, and Y. Duan, A mPEG-PLGA-b-PLL copolymer carrier for adriamycin and siRNA delivery. Biomaterials 33, 4403 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 4403
-
-
Liu, P.1
Yu, H.2
Sun, Y.3
Zhu, M.4
Duan, Y.5
-
68
-
-
38749103118
-
Biodegradable polymers as non-viral carriers for plasmid DNA delivery
-
J. Luten, C. F. van Nostrum, S. C. De Smedt, and W. E. Hennink, Biodegradable polymers as non-viral carriers for plasmid DNA delivery. J. Control. Release 126, 97 (2008).
-
(2008)
J. Control. Release
, vol.126
, pp. 97
-
-
Luten, J.1
Van Nostrum, C.F.2
De Smedt, S.C.3
Hennink, W.E.4
-
69
-
-
0035980982
-
Design and gene delivery activity of modified polyethylenimines
-
R. Kircheis, L. Wightman, and E. Wagner, Design and gene delivery activity of modified polyethylenimines. Adv. Drug. Deliv. Rev. 53, 341 (2001).
-
(2001)
Adv. Drug. Deliv. Rev.
, vol.53
, pp. 341
-
-
Kircheis, R.1
Wightman, L.2
Wagner, E.3
-
70
-
-
79952317711
-
Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung
-
M. Gunther, J. Lipka, A. Malek, D. Gutsch, W. Kreyling, and A. Aigner, Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung. Eur. J. Pharm. Biopharm. 77, 438 (2011).
-
(2011)
Eur. J. Pharm. Biopharm.
, vol.77
, pp. 438
-
-
Gunther, M.1
Lipka, J.2
Malek, A.3
Gutsch, D.4
Kreyling, W.5
Aigner, A.6
-
71
-
-
0035214028
-
Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine
-
M. A. Gosselin, W. Guo, and R. J. Lee, Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine. Bioconjug. Chem. 12, 989 (2001).
-
(2001)
Bioconjug. Chem.
, vol.12
, pp. 989
-
-
Gosselin, M.A.1
Guo, W.2
Lee, R.J.3
-
72
-
-
33748994569
-
Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/ SiRNA polyplexes
-
S. Mao, M. Neu, O. Germershaus, O. Merkel, J. Sitterberg, U. Bakowsky, and T. Kissel, Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft- poly(ethylene glycol) block copolymer/ SiRNA polyplexes. Bioconjug. Chem. 17, 1209 (2006).
-
(2006)
Bioconjug. Chem.
, vol.17
, pp. 1209
-
-
Mao, S.1
Neu, M.2
Germershaus, O.3
Merkel, O.4
Sitterberg, J.5
Bakowsky, U.6
Kissel, T.7
-
73
-
-
79955468361
-
Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice
-
A. Beyerle, A. Braun, O. Merkel, F. Koch, T. Kissel, and T. Stoeger, Comparative in vivo study of poly(ethylene imine)/siRNA complexes for pulmonary delivery in mice. J. Control. Release 151, 51 (2011).
-
(2011)
J. Control. Release
, vol.151
, pp. 51
-
-
Beyerle, A.1
Braun, A.2
Merkel, O.3
Koch, F.4
Kissel, T.5
Stoeger, T.6
-
74
-
-
75749087130
-
PEI grafted hyperbranched polymers with polyglycerol as a core for gene delivery
-
L. Zhang, C. H. Hu, S. X. Cheng, and R. X. Zhuo, PEI grafted hyperbranched polymers with polyglycerol as a core for gene delivery. Colloids Surf. B Biointerfaces 76, 427 (2010).
-
(2010)
Colloids Surf. B Biointerfaces
, vol.76
, pp. 427
-
-
Zhang, L.1
Hu, C.H.2
Cheng, S.X.3
Zhuo, R.X.4
-
75
-
-
70350707597
-
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
-
Y. B. Patil, S. K. Swaminathan, T. Sadhukha, L. Ma, and J. Panyam, The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials 31, 358 (2010).
-
(2010)
Biomaterials
, vol.31
, pp. 358
-
-
Patil, Y.B.1
Swaminathan, S.K.2
Sadhukha, T.3
Ma, L.4
Panyam, J.5
-
76
-
-
66149138398
-
Hyperbranched PEI with various oligosaccharide architectures: Synthesis, characterization, ATP complexation, and cellular uptake properties
-
D. Appelhans, H. Komber, M. A. Quadir, S. Richter, S. Schwarz, J. van der Vlist, A. Aigner, M. Muller, K. Loos, J. Seidel, K. F. Arndt, R. Haag, and B. Voit, Hyperbranched PEI with various oligosaccharide architectures: Synthesis, characterization, ATP complexation, and cellular uptake properties. Biomacromolecules 10, 1114 (2009).
-
(2009)
Biomacromolecules
, vol.10
, pp. 1114
-
-
Appelhans, D.1
Komber, H.2
Quadir, M.A.3
Richter, S.4
Schwarz, S.5
Van Der Vlist, J.6
Aigner, A.7
Muller, M.8
Loos, K.9
Seidel, J.10
Arndt, K.F.11
Haag, R.12
Voit, B.13
-
77
-
-
78651376884
-
Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes
-
S. Hobel, A. Loos, D. Appelhans, S. Schwarz, J. Seidel, B. Voit, and A. Aigner, Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): Physicochemical and biological properties of DNA and siRNA complexes. J. Control. Release 149, 146 (2011).
-
(2011)
J. Control. Release
, vol.149
, pp. 146
-
-
Hobel, S.1
Loos, A.2
Appelhans, D.3
Schwarz, S.4
Seidel, J.5
Voit, B.6
Aigner, A.7
-
78
-
-
47749100430
-
Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity
-
A. Zintchenko, A. Philipp, A. Dehshahri, and E. Wagner, Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity. Bioconjug. Chem. 19, 1448 (2008).
-
(2008)
Bioconjug. Chem.
, vol.19
, pp. 1448
-
-
Zintchenko, A.1
Philipp, A.2
Dehshahri, A.3
Wagner, E.4
-
79
-
-
0037376258
-
Synergistic effect of polyethylenimine and cationic liposomes in nucleic acid delivery to human cancer cells
-
C. H. Lee, Y. H. Ni, C. C. Chen, C. Chou, and F. H. Chang, Synergistic effect of polyethylenimine and cationic liposomes in nucleic acid delivery to human cancer cells. Biochim. Biophys. Acta. 1611, 55 (2003).
-
(2003)
Biochim. Biophys. Acta
, vol.1611
, pp. 55
-
-
Lee, C.H.1
Ni, Y.H.2
Chen, C.C.3
Chou, C.4
Chang, F.H.5
-
80
-
-
77954386915
-
Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery
-
J. Schafer, S. Hobel, U. Bakowsky, and A. Aigner, Liposome- polyethylenimine complexes for enhanced DNA and siRNA delivery. Biomaterials 31, 6892 (2010).
-
(2010)
Biomaterials
, vol.31
, pp. 6892
-
-
Schafer, J.1
Hobel, S.2
Bakowsky, U.3
Aigner, A.4
-
81
-
-
32844463723
-
Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells under in vitro conditions
-
J. Pelisek, L. Gaedtke, J. DeRouchey, G. F. Walker, S. Nikol, and E. Wagner, Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells under in vitro conditions. J. Gene. Med. 8, 186 (2006).
-
(2006)
J. Gene. Med.
, vol.8
, pp. 186
-
-
Pelisek, J.1
Gaedtke, L.2
DeRouchey, J.3
Walker, G.F.4
Nikol, S.5
Wagner, E.6
-
82
-
-
70449700090
-
Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery
-
O. Taratula, O. B. Garbuzenko, P. Kirkpatrick, I. Pandya, R. Savla, V. P. Pozharov, H. He, and T. Minko, Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery. J. Control Release 140, 284 (2009).
-
(2009)
J. Control Release
, vol.140
, pp. 284
-
-
Taratula, O.1
Garbuzenko, O.B.2
Kirkpatrick, P.3
Pandya, I.4
Savla, R.5
Pozharov, V.P.6
He, H.7
Minko, T.8
-
83
-
-
9744281157
-
PAMAM-PEG-PAMAM: Novel triblock copolymer as a biocompatible and efficient gene delivery carrier
-
T. I. Kim, H. J. Seo, J. S. Choi, H. S. Jang, J. U. Baek, K. Kim, and J. S. Park, PAMAM-PEG-PAMAM: novel triblock copolymer as a biocompatible and efficient gene delivery carrier. Biomacromolecules 5, 2487 (2004).
-
(2004)
Biomacromolecules
, vol.5
, pp. 2487
-
-
Kim, T.I.1
Seo, H.J.2
Choi, J.S.3
Jang, H.S.4
Baek, J.U.5
Kim, K.6
Park, J.S.7
-
84
-
-
70349976881
-
In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia
-
K. Watanabe, M. Harada-Shiba, A. Suzuki, R. Gokuden, R. Kurihara, Y. Sugao, T. Mori, Y. Katayama, and T. Niidome, In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia. Mol. Biosyst. 5, 1306 (2009).
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 1306
-
-
Watanabe, K.1
Harada-Shiba, M.2
Suzuki, A.3
Gokuden, R.4
Kurihara, R.5
Sugao, Y.6
Mori, T.7
Katayama, Y.8
Niidome, T.9
-
85
-
-
34248576048
-
Design and creation of new nanomaterials for therapeutic RNAi
-
H. Baigude, J. McCarroll, C. S. Yang, P. M. Swain, and T. M. Rana, Design and creation of new nanomaterials for therapeutic RNAi. ACS Chem. Biol. 2, 237 (2007).
-
(2007)
ACS Chem. Biol.
, vol.2
, pp. 237
-
-
Baigude, H.1
McCarroll, J.2
Yang, C.S.3
Swain, P.M.4
Rana, T.M.5
-
86
-
-
77958195743
-
Dendritic polyglycerols with oligoamine shells show low toxicity and high siRNA transfection efficiency in vitro
-
W. Fischer, M. Calderon, A. Schulz, I. Andreou, M. Weber, and R. Haag, Dendritic polyglycerols with oligoamine shells show low toxicity and high siRNA transfection efficiency in vitro. Bioconjug. Chem. 21, 1744 (2010).
-
(2010)
Bioconjug. Chem.
, vol.21
, pp. 1744
-
-
Fischer, W.1
Calderon, M.2
Schulz, A.3
Andreou, I.4
Weber, M.5
Haag, R.6
-
87
-
-
77956633797
-
In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers
-
P. Ofek, W. Fischer, M. Calderon, R. Haag, and R. Satchi-Fainaro, In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers. FASEB J. 24, 3122 (2010).
-
(2010)
FASEB J
, vol.24
, pp. 3122
-
-
Ofek, P.1
Fischer, W.2
Calderon, M.3
Haag, R.4
Satchi-Fainaro, R.5
-
88
-
-
77953702051
-
Dendrimer toxicity: Let's meet the challenge
-
K. Jain, P. Kesharwani, U. Gupta, and N. K. Jain, Dendrimer toxicity: Let's meet the challenge. Int. J. Pharm. 394, 122 (2010).
-
(2010)
Int. J. Pharm.
, vol.394
, pp. 122
-
-
Jain, K.1
Kesharwani, P.2
Gupta, U.3
Jain, N.K.4
-
89
-
-
0037452428
-
The influence of surface modification on the cytotoxicity of PAMAM dendrimers
-
R. Jevprasesphant, J. Penny, R. Jalal, D. Attwood, N. B. McKeown, and A. D'Emanuele, The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int. J. Pharm. 252, 263 (2003).
-
(2003)
Int. J. Pharm.
, vol.252
, pp. 263
-
-
Jevprasesphant, R.1
Penny, J.2
Jalal, R.3
Attwood, D.4
McKeown, N.B.5
D'Emanuele, A.6
-
90
-
-
36849034047
-
Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability
-
R. B. Kolhatkar, K. M. Kitchens, P. W. Swaan, and H. Ghandehari, Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability. Bioconjug. Chem. 18, 2054 (2007).
-
(2007)
Bioconjug. Chem.
, vol.18
, pp. 2054
-
-
Kolhatkar, R.B.1
Kitchens, K.M.2
Swaan, P.W.3
Ghandehari, H.4
-
92
-
-
33845216721
-
PEG conjugated VEGF siRNA for anti-angiogenic gene therapy
-
S. H. Kim, J. H. Jeong, S. H. Lee, S. W. Kim, and T. G. Park, PEG conjugated VEGF siRNA for anti-angiogenic gene therapy. J. Control. Release 116, 123 (2006).
-
(2006)
J. Control. Release
, vol.116
, pp. 123
-
-
Kim, S.H.1
Jeong, J.H.2
Lee, S.H.3
Kim, S.W.4
Park, T.G.5
-
93
-
-
47249085509
-
Reversible siRNA-polymer conjugates by RAFT polymerization
-
K. L. Heredia, T. H. Nguyen, C. W. Chang, V. Bulmus, T. P. Davis, and H. D. Maynard, Reversible siRNA-polymer conjugates by RAFT polymerization. Chem. Commun. (Camb) 3245 (2008).
-
(2008)
Chem. Commun. (Camb)
, pp. 3245
-
-
Heredia, K.L.1
Nguyen, T.H.2
Chang, C.W.3
Bulmus, V.4
Davis, T.P.5
Maynard, H.D.6
-
94
-
-
79953844934
-
Conjugation of siRNA with comb-type PEG enhances serum stability and gene silencing efficiency
-
K. Gunasekaran, T. H. Nguyen, H. D. Maynard, T. P. Davis, and V. Bulmus, Conjugation of siRNA with comb-type PEG enhances serum stability and gene silencing efficiency. Macromol. Rapid. Commun. 32, 654 (2011).
-
(2011)
Macromol. Rapid. Commun.
, vol.32
, pp. 654
-
-
Gunasekaran, K.1
Nguyen, T.H.2
Maynard, H.D.3
Davis, T.P.4
Bulmus, V.5
-
95
-
-
13644254495
-
Lactosylated poly(ethylene glycol)-siRNA conjugate through acidlabile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells
-
M. Oishi, Y. Nagasaki, K. Itaka, N. Nishiyama, and K. Kataoka, Lactosylated poly(ethylene glycol)-siRNA conjugate through acidlabile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells. J. Am. Chem. Soc. 127, 1624 (2005).
-
(2005)
J. Am. Chem. Soc.
, vol.127
, pp. 1624
-
-
Oishi, M.1
Nagasaki, Y.2
Itaka, K.3
Nishiyama, N.4
Kataoka, K.5
-
96
-
-
79952075437
-
Di- and triblock siRNA-PEG copolymers: PEG density effect of polyelectrolyte complexes on cellular uptake and gene silencing efficiency
-
S. H. Lee, H. Mok, and T. G. Park, Di- and triblock siRNA-PEG copolymers: PEG density effect of polyelectrolyte complexes on cellular uptake and gene silencing efficiency. Macromol. Biosci. 11, 410 (2011).
-
(2011)
Macromol. Biosci.
, vol.11
, pp. 410
-
-
Lee, S.H.1
Mok, H.2
Park, T.G.3
-
97
-
-
83655165245
-
Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
-
H. K. Makadia and S. J. Siegel, Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier. Polymers (Basel) 3, 1377 (2011).
-
(2011)
Polymers (Basel)
, vol.3
, pp. 1377
-
-
Makadia, H.K.1
Siegel, S.J.2
-
98
-
-
84862673737
-
PLGA-based nanoparticles: An overview of biomedical applications
-
F. Danhier, E. Ansorena, J. M. Silva, R. Coco, A. Le Breton, and V. Preat, PLGA-based nanoparticles: An overview of biomedical applications. J. Control Release 161, 505 (2012).
-
(2012)
J. Control Release
, vol.161
, pp. 505
-
-
Danhier, F.1
Ansorena, E.2
Silva, J.M.3
Coco, R.4
Le Breton, A.5
Preat, V.6
-
99
-
-
0041181628
-
HPMA copolymeranticancer drug conjugates: Design, activity, and mechanism of action
-
J. Kopecek, P. Kopeckova, T. Minko, and Z. Lu, HPMA copolymeranticancer drug conjugates: design, activity, and mechanism of action. Eur. J. Pharm. Biopharm. 50, 61 (2000).
-
(2000)
Eur. J. Pharm. Biopharm.
, vol.50
, pp. 61
-
-
Kopecek, J.1
Kopeckova, P.2
Minko, T.3
Lu, Z.4
-
100
-
-
0023141221
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro
-
R. Duncan, P. Kopeckova-Rejmanova, J. Strohalm, I. Hume, H. C. Cable, J. Pohl, J. B. Lloyd, and J. Kopecek, Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. I. Evaluation of daunomycin and puromycin conjugates in vitro. Br. J. Cancer 55, 165 (1987).
-
(1987)
Br. J. Cancer
, vol.55
, pp. 165
-
-
Duncan, R.1
Kopeckova-Rejmanova, P.2
Strohalm, J.3
Hume, I.4
Cable, H.C.5
Pohl, J.6
Lloyd, J.B.7
Kopecek, J.8
-
101
-
-
0026069645
-
Synthetic polymers conjugated to monoclonal antibodies: Vehicles for tumour-targeted drug delivery
-
L. W. Seymour, P. A. Flanagan, A. Al-Shamkhani, V. Subr, K. Ulbrich, J. Cassidy, and R. Duncan, Synthetic polymers conjugated to monoclonal antibodies: Vehicles for tumour-targeted drug delivery. Sel. Cancer Ther. 7, 59 (1991).
-
(1991)
Sel. Cancer Ther.
, vol.7
, pp. 59
-
-
Seymour, L.W.1
Flanagan, P.A.2
Al-Shamkhani, A.3
Subr, V.4
Ulbrich, K.5
Cassidy, J.6
Duncan, R.7
-
102
-
-
1042288957
-
HPMA copolymer-bound doxorubicin targeted to tumor-specific antigen of BCL1 mouse B cell leukemia
-
M. Kovar, T. Mrkvan, J. Strohalm, T. Etrych, K. Ulbrich, M. Stastny, and B. Rihova, HPMA copolymer-bound doxorubicin targeted to tumor-specific antigen of BCL1 mouse B cell leukemia. J. Control. Release 92, 315 (2003).
-
(2003)
J. Control. Release
, vol.92
, pp. 315
-
-
Kovar, M.1
Mrkvan, T.2
Strohalm, J.3
Etrych, T.4
Ulbrich, K.5
Stastny, M.6
Rihova, B.7
-
103
-
-
70349784954
-
Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate
-
K. Miller, R. Erez, E. Segal, D. Shabat, and R. Satchi-Fainaro, Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate. Angew. Chem. Int. Ed. Engl. 48, 2949 (2009).
-
(2009)
Angew. Chem. Int. Ed. Engl.
, vol.48
, pp. 2949
-
-
Miller, K.1
Erez, R.2
Segal, E.3
Shabat, D.4
Satchi-Fainaro, R.5
-
104
-
-
0343938838
-
DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers
-
D. Oupicky, C. Konak, K. Ulbrich, M. A. Wolfert, and L. W. Seymour, DNA delivery systems based on complexes of DNA with synthetic polycations and their copolymers. J. Control. Release 65, 149 (2000).
-
(2000)
J. Control. Release
, vol.65
, pp. 149
-
-
Oupicky, D.1
Konak, C.2
Ulbrich, K.3
Wolfert, M.A.4
Seymour, L.W.5
-
105
-
-
84858749727
-
Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery
-
J. Shi, R. N. Johnson, J. G. Schellinger, P. M. Carlson, and S. H. Pun, Reducible HPMA-co-oligolysine copolymers for nucleic acid delivery. Int. J. Pharm. 427, 113 (2012).
-
(2012)
Int. J. Pharm.
, vol.427
, pp. 113
-
-
Shi, J.1
Johnson, R.N.2
Schellinger, J.G.3
Carlson, P.M.4
Pun, S.H.5
-
106
-
-
80054115169
-
HPMA-oligolysine copolymers for gene delivery: Optimization of peptide length and polymer molecular weight
-
R. N. Johnson, D. S. Chu, J. Shi, J. G. Schellinger, P. M. Carlson, and S. H. Pun, HPMA-oligolysine copolymers for gene delivery: optimization of peptide length and polymer molecular weight. J. Control. Release 155, 303 (2011).
-
(2011)
J. Control. Release
, vol.155
, pp. 303
-
-
Johnson, R.N.1
Chu, D.S.2
Shi, J.3
Schellinger, J.G.4
Carlson, P.M.5
Pun, S.H.6
-
107
-
-
84861215176
-
Preparation and characterization of guanidinated N-3-aminopropyl methacrylamide-N-2-hydroxypropyl methacrylamide copolymers as gene delivery carriers
-
Z. Qin, W. Liu, L. Guo, and X. Li, Preparation and characterization of guanidinated N-3-aminopropyl methacrylamide-N-2-hydroxypropyl methacrylamide copolymers as gene delivery carriers. J. Control. Release 152 Suppl 1, e168 (2011).
-
(2011)
J. Control. Release
, vol.152
, Issue.SUPPL. 1
-
-
Qin, Z.1
Liu, W.2
Guo, L.3
Li, X.4
-
108
-
-
77950838438
-
Tailored design of Au nanoparticle-siRNA carriers utilizing reversible addition-fragmentation chain transfer polymers
-
S. Kirkland-York, Y. Zhang, A. E. Smith, A. W. York, F. Huang, and C. L. McCormick, Tailored design of Au nanoparticle-siRNA carriers utilizing reversible addition-fragmentation chain transfer polymers. Biomacromolecules 11, 1052 (2010).
-
(2010)
Biomacromolecules
, vol.11
, pp. 1052
-
-
Kirkland-York, S.1
Zhang, Y.2
Smith, A.E.3
York, A.W.4
Huang, F.5
McCormick, C.L.6
-
109
-
-
0032211994
-
Delivery of antisense oligonucleotides using HPMA polymer: Synthesis of A thiol polymer and its conjugation to water-soluble molecules
-
L. Wang, J. Kristensen, and D. E. Ruffner, Delivery of antisense oligonucleotides using HPMA polymer: Synthesis of A thiol polymer and its conjugation to water-soluble molecules. Bioconjug. Chem. 9, 749 (1998).
-
(1998)
Bioconjug. Chem.
, vol.9
, pp. 749
-
-
Wang, L.1
Kristensen, J.2
Ruffner, D.E.3
-
110
-
-
76249125385
-
Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers
-
A. W. York, F. Huang, and C. L. McCormick, Rational design of targeted cancer therapeutics through the multiconjugation of folate and cleavable siRNA to RAFT-synthesized (HPMA-s-APMA) copolymers. Biomacromolecules 11, 505 (2010).
-
(2010)
Biomacromolecules
, vol.11
, pp. 505
-
-
York, A.W.1
Huang, F.2
McCormick, C.L.3
-
111
-
-
0025010857
-
Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes
-
E. P. Feener, W. C. Shen, and H. J. Ryser, Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes. J. Biol. Chem. 265, 18780 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 18780
-
-
Feener, E.P.1
Shen, W.C.2
Ryser, H.J.3
-
112
-
-
0036738632
-
Antisense oligonucleotides delivered to the lysosome escape and actively inhibit the hepatitis B virus
-
K. D. Jensen, P. Kopeckova, and J. Kopecek, Antisense oligonucleotides delivered to the lysosome escape and actively inhibit the hepatitis B virus. Bioconjug. Chem. 13, 975 (2002).
-
(2002)
Bioconjug. Chem.
, vol.13
, pp. 975
-
-
Jensen, K.D.1
Kopeckova, P.2
Kopecek, J.3
-
113
-
-
84865180636
-
Anisamide-targeted cyclodextrin nanoparticles for siRNA delivery to prostate tumours in mice
-
J. Guo, J. R. Ogier, S. Desgranges, R. Darcy, and C. O'Driscoll, Anisamide-targeted cyclodextrin nanoparticles for siRNA delivery to prostate tumours in mice. Biomaterials 33, 7775 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 7775
-
-
Guo, J.1
Ogier, J.R.2
Desgranges, S.3
Darcy, R.4
O'Driscoll, C.5
-
114
-
-
80053923147
-
Systemic delivery of siRNA via targeted nanoparticles in patients with cancer: Results from a first-in-class phase I clinical trial
-
2010 ASCO Annual Meeting
-
L. K. A. Ribas, J. D. Heidel, J. Peterkin, D. B. Seligson, J. E. Zuckerman, C. Choi, Y. Yen, M. E. Davis, and A. W. Tolcher, Systemic delivery of siRNA via targeted nanoparticles in patients with cancer: Results from a first-in-class phase I clinical trial., in 2010 ASCO Annual Meeting. J. Clin. Oncol. 28, 15s (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
-
-
Ribas, L.K.A.1
Heidel, J.D.2
Peterkin, J.3
Seligson, D.B.4
Zuckerman, J.E.5
Choi, C.6
Yen, Y.7
Davis, M.E.8
Tolcher, A.W.9
-
115
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
M. E. Davis, J. E. Zuckerman, C. H. Choi, D. Seligson, A. Tolcher, C. A. Alabi, Y. Yen, J. D. Heidel, and A. Ribas, Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 464, 1067 (2010).
-
(2010)
Nature
, vol.464
, pp. 1067
-
-
Davis, M.E.1
Zuckerman, J.E.2
Choi, C.H.3
Seligson, D.4
Tolcher, A.5
Alabi, C.A.6
Yen, Y.7
Heidel, J.D.8
Ribas, A.9
-
116
-
-
84867496487
-
A highly entangled polymeric nanoconstruct assembled by siRNA and its reduction-triggered siRNA release for gene silencing
-
R. Namgung and W. J. Kim, A highly entangled polymeric nanoconstruct assembled by siRNA and its reduction-triggered siRNA release for gene silencing. Small 8, 3209 (2012).
-
(2012)
Small
, vol.8
, pp. 3209
-
-
Namgung, R.1
Kim, W.J.2
-
117
-
-
84862872331
-
Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection
-
R. J. Christie, Y. Matsumoto, K. Miyata, T. Nomoto, S. Fukushima, K. Osada, J. Halnaut, F. Pittella, H. J. Kim, N. Nishiyama, and K. Kataoka, Targeted Polymeric Micelles for siRNA Treatment of Experimental Cancer by Intravenous Injection. ACS Nano 6, 5174 (2012).
-
(2012)
ACS Nano
, vol.6
, pp. 5174
-
-
Christie, R.J.1
Matsumoto, Y.2
Miyata, K.3
Nomoto, T.4
Fukushima, S.5
Osada, K.6
Halnaut, J.7
Pittella, F.8
Kim, H.J.9
Nishiyama, N.10
Kataoka, K.11
-
118
-
-
84868123808
-
Synergistic anticancer effect of RNAi and photothermal therapy mediated by functionalized single-walled carbon nanotubes
-
L. Wang, J. Shi, H. Zhang, H. Li, Y. Gao, Z. Wang, H. Wang, L. Li, C. Zhang, C. Chen, Z. Zhang, and Y. Zhang, Synergistic anticancer effect of RNAi and photothermal therapy mediated by functionalized single-walled carbon nanotubes. Biomaterials 34, 262 (2013).
-
(2013)
Biomaterials
, vol.34
, pp. 262
-
-
Wang, L.1
Shi, J.2
Zhang, H.3
Li, H.4
Gao, Y.5
Wang, Z.6
Wang, H.7
Li, L.8
Zhang, C.9
Chen, C.10
Zhang, Z.11
Zhang, Y.12
-
119
-
-
84857370161
-
Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo
-
W. Xia, P. Wang, C. Lin, Z. Li, X. Gao, G. Wang, and X. Zhao, Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo. J. Control. Release 157, 427 (2012).
-
(2012)
J. Control. Release
, vol.157
, pp. 427
-
-
Xia, W.1
Wang, P.2
Lin, C.3
Li, Z.4
Gao, X.5
Wang, G.6
Zhao, X.7
-
120
-
-
84866548075
-
Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex
-
M. Han, Q. Lv, X. J. Tang, Y. L. Hu, D. H. Xu, F. Z. Li, W. Q. Liang, and J. Q. Gao, Overcoming drug resistance of MCF-7/ADR cells by altering intracellular distribution of doxorubicin via MVP knockdown with a novel siRNA polyamidoamine-hyaluronic acid complex. J. Control. Release 163, 136 (2012).
-
(2012)
J. Control. Release
, vol.163
, pp. 136
-
-
Han, M.1
Lv, Q.2
Tang, X.J.3
Hu, Y.L.4
Xu, D.H.5
Li, F.Z.6
Liang, W.Q.7
Gao, J.Q.8
-
121
-
-
84870368308
-
Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery
-
S. Biswas, P. P. Deshpande, G. Navarro, N. S. Dodwadkar, and V. P. Torchilin, Lipid modified triblock PAMAM-based nanocarriers for siRNA drug co-delivery. Biomaterials 34, 1289 (2013).
-
(2013)
Biomaterials
, vol.34
, pp. 1289
-
-
Biswas, S.1
Deshpande, P.P.2
Navarro, G.3
Dodwadkar, N.S.4
Torchilin, V.P.5
-
122
-
-
80055103805
-
Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors
-
J. Zhou, T. R. Patel, M. Fu, J. P. Bertram, and W. M. Saltzman, Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors. Biomaterials 33, 583 (2012).
-
(2012)
Biomaterials
, vol.33
, pp. 583
-
-
Zhou, J.1
Patel, T.R.2
Fu, M.3
Bertram, J.P.4
Saltzman, W.M.5
-
123
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
C. L. Vogel, M. A. Cobleigh, D. Tripathy, J. C. Gutheil, L. N. Harris, L. Fehrenbacher, D. J. Slamon, M. Murphy, W. F. Novotny, M. Burchmore, S. Shak, S. J. Stewart, and M. Press, Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J. Clin. Oncol. 20, 719 (2002).
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 719
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
Gutheil, J.C.4
Harris, L.N.5
Fehrenbacher, L.6
Slamon, D.J.7
Murphy, M.8
Novotny, W.F.9
Burchmore, M.10
Shak, S.11
Stewart, S.J.12
Press, M.13
-
124
-
-
33845444046
-
Five-year followup of patients receiving imatinib for chronic myeloid leukemia
-
B. J. Druker, F. Guilhot, S. G. O'Brien, I. Gathmann, H. Kantarjian, N. Gattermann, M. W. Deininger, R. T. Silver, J. M. Goldman, R. M. Stone, F. Cervantes, A. Hochhaus, B. L. Powell, J. L. Gabrilove, P. Rousselot, J. Reiffers, J. J. Cornelissen, T. Hughes, H. Agis, T. Fischer, G. Verhoef, J. Shepherd, G. Saglio, A. Gratwohl, J. L. Nielsen, J. P. Radich, B. Simonsson, K. Taylor, M. Baccarani, C. So, L. Letvak, and R. A. Larson, Five-year followup of patients receiving imatinib for chronic myeloid leukemia. N. Engl. J. Med. 355, 2408 (2006).
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 2408
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
Gathmann, I.4
Kantarjian, H.5
Gattermann, N.6
Deininger, M.W.7
Silver, R.T.8
Goldman, J.M.9
Stone, R.M.10
Cervantes, F.11
Hochhaus, A.12
Powell, B.L.13
Gabrilove, J.L.14
Rousselot, P.15
Reiffers, J.16
Cornelissen, J.J.17
Hughes, T.18
Agis, H.19
Fischer, T.20
Verhoef, G.21
Shepherd, J.22
Saglio, G.23
Gratwohl, A.24
Nielsen, J.L.25
Radich, J.P.26
Simonsson, B.27
Taylor, K.28
Baccarani, M.29
So, C.30
Letvak, L.31
Larson, R.A.32
more..
-
125
-
-
33750205340
-
A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
-
H. Asahina, K. Yamazaki, I. Kinoshita, N. Sukoh, M. Harada, H. Yokouchi, T. Ishida, S. Ogura, T. Kojima, Y. Okamoto, Y. Fujita, H. Dosaka-Akita, H. Isobe, and M. Nishimura, A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations. Br. J. Cancer 95, 998 (2006).
-
(2006)
Br. J. Cancer
, vol.95
, pp. 998
-
-
Asahina, H.1
Yamazaki, K.2
Kinoshita, I.3
Sukoh, N.4
Harada, M.5
Yokouchi, H.6
Ishida, T.7
Ogura, S.8
Kojima, T.9
Okamoto, Y.10
Fujita, Y.11
Dosaka-Akita, H.12
Isobe, H.13
Nishimura, M.14
-
126
-
-
0018095254
-
Tamoxifen: A review of its pharmacological properties and therapeutic use in the treatment of breast cancer
-
R. C. Heel, R. N. Brogden, T. M. Speight, and G. S. Avery, Tamoxifen: A review of its pharmacological properties and therapeutic use in the treatment of breast cancer. Drugs 16, 1 (1978).
-
(1978)
Drugs
, vol.16
, pp. 1
-
-
Heel, R.C.1
Brogden, R.N.2
Speight, T.M.3
Avery, G.S.4
-
127
-
-
4043181214
-
Cancer genes and the pathways they control
-
B. Vogelstein and K. W. Kinzler, Cancer genes and the pathways they control. Nat. Med. 10, 789 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. 789
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
128
-
-
33645167401
-
Prospects of RNA interference therapy for cancer
-
S. I. Pai, Y. Y. Lin, B. Macaes, A. Meneshian, C. F. Hung, and T. C. Wu, Prospects of RNA interference therapy for cancer. Gene. Ther. 13, 464 (2006).
-
(2006)
Gene. Ther.
, vol.13
, pp. 464
-
-
Pai, S.I.1
Lin, Y.Y.2
Macaes, B.3
Meneshian, A.4
Hung, C.F.5
Wu, T.C.6
-
129
-
-
2942590261
-
Vascular endothelial growth factor as a target for anticancer therapy
-
N. Ferrara, Vascular endothelial growth factor as a target for anticancer therapy. Oncologist 9 Suppl 1, 2 (2004).
-
(2004)
Oncologist
, vol.9
, Issue.SUPPL. 1
, pp. 2
-
-
Ferrara, N.1
-
130
-
-
81255143432
-
Innovative strategy for treatment of lung cancer: Targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA
-
O. Taratula, O. B. Garbuzenko, A. M. Chen, and T. Minko, Innovative strategy for treatment of lung cancer: targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA. J. Drug. Target. 19, 900 (2011).
-
(2011)
J. Drug. Target.
, vol.19
, pp. 900
-
-
Taratula, O.1
Garbuzenko, O.B.2
Chen, A.M.3
Minko, T.4
-
131
-
-
22944447177
-
Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: Justification for K-ras-directed therapy
-
J. B. Fleming, G. L. Shen, S. E. Holloway, M. Davis, and R. A. Brekken, Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: Justification for K-ras-directed therapy. Mol. Cancer Res. 3, 413 (2005).
-
(2005)
Mol. Cancer Res.
, vol.3
, pp. 413
-
-
Fleming, J.B.1
Shen, G.L.2
Holloway, S.E.3
Davis, M.4
Brekken, R.A.5
-
132
-
-
79960052850
-
Ras in cancer and developmental diseases
-
A. Fernandez-Medarde and E. Santos, Ras in cancer and developmental diseases. Genes. Cancer 2, 344 (2011).
-
(2011)
Genes. Cancer
, vol.2
, pp. 344
-
-
Fernandez-Medarde, A.1
Santos, E.2
-
133
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
J. Folkman, Tumor angiogenesis: Therapeutic implications. N. Engl. J. Med. 285, 1182 (1971).
-
(1971)
N. Engl. J. Med.
, vol.285
, pp. 1182
-
-
Folkman, J.1
-
134
-
-
65349125338
-
Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics
-
E. Segal, H. Pan, P. Ofek, T. Udagawa, P. Kopeckova, J. Kopecek, and R. Satchi-Fainaro, Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics. PLoS One 4, e5233 (2009).
-
(2009)
PLoS One
, vol.4
-
-
Segal, E.1
Pan, H.2
Ofek, P.3
Udagawa, T.4
Kopeckova, P.5
Kopecek, J.6
Satchi-Fainaro, R.7
-
135
-
-
78049349257
-
Receptor-targeted nanocarriers for therapeutic delivery to cancer
-
B. Yu, H. C. Tai, W. Xue, L. J. Lee, and R. J. Lee, Receptor-targeted nanocarriers for therapeutic delivery to cancer. Mol. Membr. Biol. 27, 286 (2010).
-
(2010)
Mol. Membr. Biol.
, vol.27
, pp. 286
-
-
Yu, B.1
Tai, H.C.2
Xue, W.3
Lee, L.J.4
Lee, R.J.5
-
136
-
-
84857371220
-
The transferrin receptor and the targeted delivery of therapeutic agents against cancer
-
T. R. Daniels, E. Bernabeu, J. A. Rodriguez, S. Patel, M. Kozman, D. A. Chiappetta, E. Holler, J. Y. Ljubimova, G. Helguera, and M. L. Penichet, The transferrin receptor and the targeted delivery of therapeutic agents against cancer. Biochim. Biophys. Acta. 1820, 291 (2012).
-
(2012)
Biochim. Biophys. Acta
, vol.1820
, pp. 291
-
-
Daniels, T.R.1
Bernabeu, E.2
Rodriguez, J.A.3
Patel, S.4
Kozman, M.5
Chiappetta, D.A.6
Holler, E.7
Ljubimova, J.Y.8
Helguera, G.9
Penichet, M.L.10
-
137
-
-
5344270492
-
Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours
-
G. Russell-Jones, K. McTavish, J. McEwan, J. Rice, and D. Nowotnik, Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. J. Inorg. Biochem. 98, 1625 (2004).
-
(2004)
J. Inorg. Biochem.
, vol.98
, pp. 1625
-
-
Russell-Jones, G.1
McTavish, K.2
McEwan, J.3
Rice, J.4
Nowotnik, D.5
-
138
-
-
84868563717
-
RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis
-
F. Danhier, A. Le Breton, and V. Preat, RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis. Mol. Pharm. 9, 2961 (2012).
-
(2012)
Mol. Pharm.
, vol.9
, pp. 2961
-
-
Danhier, F.1
Le Breton, A.2
Preat, V.3
|