Polymer brush-stabilized polyplex for a siRNA carrier with long circulatory half-life

Journal of Controlled Release

Volumn 122, Issue 3, 2007, Pages 209-216

  Sato, Ayumi ^a   Choi, Sung Won ^b   Hirai, Miwa ^a   Yamayoshi, Asako ^b   Moriyama, Rui ^b   Yamano, Takeshi ^b   Takagi, Motoki ^a   Kano, Arihiro ^b   Shimamoto, Akira ^a   Maruyama, Atsushi ^b,c  

^a GeneCare Research Institute   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Blood circulation; Graft copolymer; Polymer brush; Polyplex; siRNA

Indexed keywords

BLOOD; POLYELECTROLYTES; RNA;

BLOOD CIRCULATION; CATIONIC COMB-TYPE COPOLYMERS (CCC); POLYMER BRUSH; POLYPLEX;

COPOLYMERS;

COPOLYMER; DRUG CARRIER; MACROGOL; NUCLEASE; POLYCATION; POLYELECTROLYTE; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCULATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; EVALUATION; HALF LIFE TIME; MALE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOLUBILITY;

ANIMALS; DEXTRANS; DRUG CARRIERS; DRUG STABILITY; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; MICE; MICE, INBRED ICR; POLYETHYLENE GLYCOLS; POLYLYSINE; RNA, SMALL INTERFERING; SOLUBILITY;

EID: 34548644167     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.04.018     Document Type: Article

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