-
1
-
-
60749111194
-
Recent development of nonviral gene delivery systems with virus-like structures and mechanisms
-
K. Itaka, and K. Kataoka Recent development of nonviral gene delivery systems with virus-like structures and mechanisms Eur. J. Pharm. Biopharm. 71 3 2009 475 483
-
(2009)
Eur. J. Pharm. Biopharm.
, vol.71
, Issue.3
, pp. 475-483
-
-
Itaka, K.1
Kataoka, K.2
-
2
-
-
59849090457
-
Cellular delivery in vivo of siRNA-based therapeutics
-
A. Aigner Cellular delivery in vivo of siRNA-based therapeutics Curr. Pharm. Des. 14 34 2008 3603 3619
-
(2008)
Curr. Pharm. Des.
, vol.14
, Issue.34
, pp. 3603-3619
-
-
Aigner, A.1
-
3
-
-
33749383278
-
A look to future directions in gene therapy research for monogenic diseases
-
M.H. Porteus, J.P. Connelly, and S.M. Pruett A look to future directions in gene therapy research for monogenic diseases PLoS Genet. 2 9 2006 e133
-
(2006)
PLoS Genet.
, vol.2
, Issue.9
, pp. 133
-
-
Porteus, M.H.1
Connelly, J.P.2
Pruett, S.M.3
-
4
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
O. Boussif, F. Lezoualc'h, M.A. Zanta, M.D. Mergny, D. Scherman, B. Demeneix, and J.P. Behr A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine Proc. Natl Acad. Sci. USA 92 16 1995 7297 7301
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, Issue.16
, pp. 7297-7301
-
-
Boussif, O.1
Lezoualc'H, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Behr, J.P.7
-
5
-
-
23944464631
-
Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives
-
M. Neu, D. Fischer, and T. Kissel Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives J. Gene Med. 7 8 2005 992 1009
-
(2005)
J. Gene Med.
, vol.7
, Issue.8
, pp. 992-1009
-
-
Neu, M.1
Fischer, D.2
Kissel, T.3
-
6
-
-
0032892476
-
Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
-
W.T. Godbey, K.K. Wu, and A.G. Mikos Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle J. Biomed. Mater. Res. 45 3 1999 268 275
-
(1999)
J. Biomed. Mater. Res.
, vol.45
, Issue.3
, pp. 268-275
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
7
-
-
0030775528
-
The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
-
M.X. Tang, and F.C. Szoka The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes Gene Ther. 4 8 1997 823 832
-
(1997)
Gene Ther.
, vol.4
, Issue.8
, pp. 823-832
-
-
Tang, M.X.1
Szoka, F.C.2
-
8
-
-
0035915088
-
Towards synthetic viruses
-
G. Zuber, E. Dauty, M. Nothisen, P. Belguise, and J.P. Behr Towards synthetic viruses Adv. Drug Deliv. Rev. 52 3 2001 245 253
-
(2001)
Adv. Drug Deliv. Rev.
, vol.52
, Issue.3
, pp. 245-253
-
-
Zuber, G.1
Dauty, E.2
Nothisen, M.3
Belguise, P.4
Behr, J.P.5
-
9
-
-
78650476432
-
The proton sponge: A trick to enter cells the viruses did not exploit
-
J.P. Behr The proton sponge: a trick to enter cells the viruses did not exploit Chimia 51 1997 34 36
-
(1997)
Chimia
, vol.51
, pp. 34-36
-
-
Behr, J.P.1
-
10
-
-
0033609001
-
Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery
-
W.T. Godbey, K.K. Wu, and A.G. Mikos Tracking the intracellular path of poly(ethylenimine)/DNA complexes for gene delivery Proc. Natl Acad. Sci. USA 96 9 1999 5177 5181
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.9
, pp. 5177-5181
-
-
Godbey, W.T.1
Wu, K.K.2
Mikos, A.G.3
-
11
-
-
0032571392
-
Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
-
H. Pollard, J.S. Remy, G. Loussouarn, S. Demolombe, J.P. Behr, and D. Escande Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells J. Biol. Chem. 273 13 1998 7507 7511
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.13
, pp. 7507-7511
-
-
Pollard, H.1
Remy, J.S.2
Loussouarn, G.3
Demolombe, S.4
Behr, J.P.5
Escande, D.6
-
12
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in caenorhabditis elegans
-
DOI 10.1038/35888
-
A. Fire, S. Xu, M.K. Montgomery, S.A. Kostas, S.E. Driver, and C.C. Mello Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans Nature 391 6669 1998 806 811 (Pubitemid 28099681)
-
(1998)
Nature
, vol.391
, Issue.6669
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
13
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 6836 2001 494 498
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
14
-
-
0035863097
-
RNA interference is mediated by 21- and 22-nucleotide RNAs
-
DOI 10.1101/gad.862301
-
S.M. Elbashir, W. Lendeckel, and T. Tuschl RNA interference is mediated by 21- and 22-nucleotide RNAs Genes Dev. 15 2 2001 188 200 (Pubitemid 32107664)
-
(2001)
Genes and Development
, vol.15
, Issue.2
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
15
-
-
0033615491
-
A species of small antisense RNA in posttranscriptional gene silencing in plants
-
A.J. Hamilton, and D.C. Baulcombe A species of small antisense RNA in posttranscriptional gene silencing in plants Science 286 5441 1999 950 952
-
(1999)
Science
, vol.286
, Issue.5441
, pp. 950-952
-
-
Hamilton, A.J.1
Baulcombe, D.C.2
-
16
-
-
50149105616
-
Polyethylenimine PEI F25-LMW allows the long-term storage of frozen complexes as fully active reagents in siRNA-mediated gene targeting and DNA delivery
-
S. Hobel, R. Prinz, A. Malek, B. Urban-Klein, J. Sitterberg, U. Bakowsky, F. Czubayko, and A. Aigner Polyethylenimine PEI F25-LMW allows the long-term storage of frozen complexes as fully active reagents in siRNA-mediated gene targeting and DNA delivery Eur. J. Pharm. Biopharm. 70 1 2008 29 41
-
(2008)
Eur. J. Pharm. Biopharm.
, vol.70
, Issue.1
, pp. 29-41
-
-
Hobel, S.1
Prinz, R.2
Malek, A.3
Urban-Klein, B.4
Sitterberg, J.5
Bakowsky, U.6
Czubayko, F.7
Aigner, A.8
-
17
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
B. Urban-Klein, S. Werth, S. Abuharbeid, F. Czubayko, and A. Aigner RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo Gene Ther. 12 5 2005 461 466
-
(2005)
Gene Ther.
, vol.12
, Issue.5
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
18
-
-
33746267422
-
RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenografts
-
M. Grzelinski, B. Urban-Klein, T. Martens, K. Lamszus, U. Bakowsky, S. Hobel, F. Czubayko, and A. Aigner RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenografts Hum. Gene Ther. 17 7 2006 751 766
-
(2006)
Hum. Gene Ther.
, vol.17
, Issue.7
, pp. 751-766
-
-
Grzelinski, M.1
Urban-Klein, B.2
Martens, T.3
Lamszus, K.4
Bakowsky, U.5
Hobel, S.6
Czubayko, F.7
Aigner, A.8
-
19
-
-
33646152761
-
A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes
-
S. Werth, B. Urban-Klein, L. Dai, S. Hobel, M. Grzelinski, U. Bakowsky, F. Czubayko, and A. Aigner A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes J. Control. Release 112 2 2006 257 270
-
(2006)
J. Control. Release
, vol.112
, Issue.2
, pp. 257-270
-
-
Werth, S.1
Urban-Klein, B.2
Dai, L.3
Hobel, S.4
Grzelinski, M.5
Bakowsky, U.6
Czubayko, F.7
Aigner, A.8
-
20
-
-
0037437033
-
Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
-
K. Kunath, A. von Harpe, D. Fischer, H. Petersen, U. Bickel, K. Voigt, and T. Kissel Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine J. Control. Release 89 1 2003 113 125
-
(2003)
J. Control. Release
, vol.89
, Issue.1
, pp. 113-125
-
-
Kunath, K.1
Von Harpe, A.2
Fischer, D.3
Petersen, H.4
Bickel, U.5
Voigt, K.6
Kissel, T.7
-
21
-
-
0029981092
-
Evidence for the role of proteoglycans in cation-mediated gene transfer
-
K.A. Mislick, and J.D. Baldeschwieler Evidence for the role of proteoglycans in cation-mediated gene transfer Proc. Natl Acad. Sci. USA 93 22 1996 12349 12354
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, Issue.22
, pp. 12349-12354
-
-
Mislick, K.A.1
Baldeschwieler, J.D.2
-
22
-
-
0032938324
-
PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
-
M. Ogris, S. Brunner, S. Schuller, R. Kircheis, and E. Wagner PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery Gene Ther. 6 4 1999 595 605
-
(1999)
Gene Ther.
, vol.6
, Issue.4
, pp. 595-605
-
-
Ogris, M.1
Brunner, S.2
Schuller, S.3
Kircheis, R.4
Wagner, E.5
-
23
-
-
0029789793
-
Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery
-
C. Plank, K. Mechtler, F.C. Szoka Jr., and E. Wagner Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery Hum. Gene Ther. 7 12 1996 1437 1446
-
(1996)
Hum. Gene Ther.
, vol.7
, Issue.12
, pp. 1437-1446
-
-
Plank, C.1
Mechtler, K.2
Szoka Jr., F.C.3
Wagner, E.4
-
24
-
-
3242807724
-
Gene transfer with modified polyethylenimines
-
A. Kichler Gene transfer with modified polyethylenimines J. Gene Med. 6 Suppl 1 2004 S3 S10
-
(2004)
J. Gene Med.
, vol.6
, Issue.SUPPL. 1
-
-
Kichler, A.1
-
25
-
-
0038064402
-
Tumor-targeted gene transfer with DNA polyplexes
-
M. Ogris, and E. Wagner Tumor-targeted gene transfer with DNA polyplexes Somat. Cell Mol. Genet. 27 1-6 2002 85 95
-
(2002)
Somat. Cell Mol. Genet.
, vol.27
, Issue.16
, pp. 85-95
-
-
Ogris, M.1
Wagner, E.2
-
26
-
-
39449113001
-
PEG grafting of polyethylenimine (PEI) exerts different effects on DNA transfection and siRNA-induced gene targeting efficacy
-
A. Malek, F. Czubayko, and A. Aigner PEG grafting of polyethylenimine (PEI) exerts different effects on DNA transfection and siRNA-induced gene targeting efficacy J. Drug Target. 16 2 2008 124 139
-
(2008)
J. Drug Target.
, vol.16
, Issue.2
, pp. 124-139
-
-
Malek, A.1
Czubayko, F.2
Aigner, A.3
-
27
-
-
33748994569
-
Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft-poly(ethylene glycol) block copolymer/SiRNA polyplexes
-
S. Mao, M. Neu, O. Germershaus, O. Merkel, J. Sitterberg, U. Bakowsky, and T. Kissel Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graft- poly(ethylene glycol) block copolymer/SiRNA polyplexes Bioconjug. Chem. 17 5 2006 1209 1218
-
(2006)
Bioconjug. Chem.
, vol.17
, Issue.5
, pp. 1209-1218
-
-
Mao, S.1
Neu, M.2
Germershaus, O.3
Merkel, O.4
Sitterberg, J.5
Bakowsky, U.6
Kissel, T.7
-
28
-
-
61849103493
-
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes
-
A. Malek, O. Merkel, L. Fink, F. Czubayko, T. Kissel, and A. Aigner In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI(-PEG)/siRNA complexes Toxicol. Appl. Pharmacol. 236 1 2009 97 108
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.236
, Issue.1
, pp. 97-108
-
-
Malek, A.1
Merkel, O.2
Fink, L.3
Czubayko, F.4
Kissel, T.5
Aigner, A.6
-
29
-
-
0033980841
-
Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents
-
H.K. Nguyen, P. Lemieux, S.V. Vinogradov, C.L. Gebhart, N. Guerin, G. Paradis, T.K. Bronich, V.Y. Alakhov, and A.V. Kabanov Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agents Gene Ther. 7 2 2000 126 138
-
(2000)
Gene Ther.
, vol.7
, Issue.2
, pp. 126-138
-
-
Nguyen, H.K.1
Lemieux, P.2
Vinogradov, S.V.3
Gebhart, C.L.4
Guerin, N.5
Paradis, G.6
Bronich, T.K.7
Alakhov, V.Y.8
Kabanov, A.V.9
-
30
-
-
45849151689
-
Efficient gene delivery using chitosan-polyethylenimine hybrid systems
-
H.L. Jiang, T.H. Kim, Y.K. Kim, I.Y. Park, M.H. Cho, and C.S. Cho Efficient gene delivery using chitosan-polyethylenimine hybrid systems Biomed. Mater. 3 2 2008 25013
-
(2008)
Biomed. Mater.
, vol.3
, Issue.2
, pp. 25013
-
-
Jiang, H.L.1
Kim, T.H.2
Kim, Y.K.3
Park, I.Y.4
Cho, M.H.5
Cho, C.S.6
-
31
-
-
77649191250
-
Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity
-
J.Q. Gao, Q.Q. Zhao, T.F. Lv, W.P. Shuai, J. Zhou, G.P. Tang, W.Q. Liang, Y. Tabata, and Y.L. Hu Gene-carried chitosan-linked-PEI induced high gene transfection efficiency with low toxicity and significant tumor-suppressive activity Int. J. Pharm. 387 1-2 2010 286 294
-
(2010)
Int. J. Pharm.
, vol.387
, Issue.12
, pp. 286-294
-
-
Gao, J.Q.1
Zhao, Q.Q.2
Lv, T.F.3
Shuai, W.P.4
Zhou, J.5
Tang, G.P.6
Liang, W.Q.7
Tabata, Y.8
Hu, Y.L.9
-
32
-
-
75449101757
-
DNA/polyethyleneimine/hyaluronic acid small complex particles and tumor suppression in mice
-
T. Ito, C. Yoshihara, K. Hamada, and Y. Koyama DNA/polyethyleneimine/ hyaluronic acid small complex particles and tumor suppression in mice Biomaterials 31 10 2010 2912 2918
-
(2010)
Biomaterials
, vol.31
, Issue.10
, pp. 2912-2918
-
-
Ito, T.1
Yoshihara, C.2
Hamada, K.3
Koyama, Y.4
-
33
-
-
75749087130
-
PEI grafted hyperbranched polymers with polyglycerol as a core for gene delivery
-
L. Zhang, C.H. Hu, S.X. Cheng, and R.X. Zhuo PEI grafted hyperbranched polymers with polyglycerol as a core for gene delivery Colloids Surf. 76 2 2010 427 433
-
(2010)
Colloids Surf.
, vol.76
, Issue.2
, pp. 427-433
-
-
Zhang, L.1
Hu, C.H.2
Cheng, S.X.3
Zhuo, R.X.4
-
34
-
-
0037069319
-
Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
-
M. Thomas, and A.M. Klibanov Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells Proc. Natl Acad. Sci. USA 99 23 2002 14640 14645
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, Issue.23
, pp. 14640-14645
-
-
Thomas, M.1
Klibanov, A.M.2
-
35
-
-
33845956651
-
Physicochemical and biological study of selected hydrophobic polyethylenimine-based polycationic liposomes and their complexes with DNA
-
A. Masotti, F. Moretti, F. Mancini, G. Russo, N. Di Lauro, P. Checchia, C. Marianecci, M. Carafa, E. Santucci, and G. Ortaggi Physicochemical and biological study of selected hydrophobic polyethylenimine-based polycationic liposomes and their complexes with DNA Bioorg. Med. Chem. 15 3 2007 1504 1515
-
(2007)
Bioorg. Med. Chem.
, vol.15
, Issue.3
, pp. 1504-1515
-
-
Masotti, A.1
Moretti, F.2
Mancini, F.3
Russo, G.4
Di Lauro, N.5
Checchia, P.6
Marianecci, C.7
Carafa, M.8
Santucci, E.9
Ortaggi, G.10
-
36
-
-
77952668878
-
Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice
-
M.S. Huh, S.Y. Lee, S. Park, S. Lee, H. Chung, S. Lee, Y. Choi, Y.K. Oh, J.H. Park, S.Y. Jeong, K. Choi, K. Kim, and I.C. Kwon Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice J. Control. Release 144 2 2010 134 143
-
(2010)
J. Control. Release
, vol.144
, Issue.2
, pp. 134-143
-
-
Huh, M.S.1
Lee, S.Y.2
Park, S.3
Lee, S.4
Chung, H.5
Lee, S.6
Choi, Y.7
Oh, Y.K.8
Park, J.H.9
Jeong, S.Y.10
Choi, K.11
Kim, K.12
Kwon, I.C.13
-
37
-
-
77954386915
-
Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery
-
J. Schafer, S. Hobel, U. Bakowsky, and A. Aigner Liposome- polyethylenimine complexes for enhanced DNA and siRNA delivery Biomaterials 31 26 2010 6892-900
-
(2010)
Biomaterials
, vol.31
, Issue.26
-
-
Schafer, J.1
Hobel, S.2
Bakowsky, U.3
Aigner, A.4
-
38
-
-
0031281282
-
In vitro gene delivery to hepatocytes with galactosylated polyethylenimine
-
M.A. Zanta, O. Boussif, A. Adib, and J.P. Behr In vitro gene delivery to hepatocytes with galactosylated polyethylenimine Bioconjug. Chem. 8 6 1997 839 844
-
(1997)
Bioconjug. Chem.
, vol.8
, Issue.6
, pp. 839-844
-
-
Zanta, M.A.1
Boussif, O.2
Adib, A.3
Behr, J.P.4
-
39
-
-
0033167367
-
Size reduction of galactosylated PEI/DNA complexes improves lectin-mediated gene transfer into hepatocytes
-
T. Bettinger, J.S. Remy, and P. Erbacher Size reduction of galactosylated PEI/DNA complexes improves lectin-mediated gene transfer into hepatocytes Bioconjug. Chem. 10 4 1999 558 561
-
(1999)
Bioconjug. Chem.
, vol.10
, Issue.4
, pp. 558-561
-
-
Bettinger, T.1
Remy, J.S.2
Erbacher, P.3
-
40
-
-
0034608330
-
Synthesis of glycosylated polyethylenimine with reduced toxicity and high transfecting efficiency
-
F. Leclercq, C. Dubertret, B. Pitard, D. Scherman, and J. Herscovici Synthesis of glycosylated polyethylenimine with reduced toxicity and high transfecting efficiency Bioorg. Med. Chem. Lett. 10 11 2000 1233 1235
-
(2000)
Bioorg. Med. Chem. Lett.
, vol.10
, Issue.11
, pp. 1233-1235
-
-
Leclercq, F.1
Dubertret, C.2
Pitard, B.3
Scherman, D.4
Herscovici, J.5
-
41
-
-
0033516472
-
Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells
-
S.S. Diebold, M. Kursa, E. Wagner, M. Cotten, and M. Zenke Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells J. Biol. Chem. 274 27 1999 19087 19094
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.27
, pp. 19087-19094
-
-
Diebold, S.S.1
Kursa, M.2
Wagner, E.3
Cotten, M.4
Zenke, M.5
-
42
-
-
0012505259
-
Uptake of plasmid/glycosylated polymer complexes and gene transfer efficiency in differentiated airway epithelial cells
-
I. Fajac, G. Thevenot, L. Bedouet, C. Danel, M. Riquet, M. Merten, C. Figarella, J. Dall'Ava-Santucci, M. Monsigny, and P. Briand Uptake of plasmid/glycosylated polymer complexes and gene transfer efficiency in differentiated airway epithelial cells J. Gene Med. 5 1 2003 38 48
-
(2003)
J. Gene Med.
, vol.5
, Issue.1
, pp. 38-48
-
-
Fajac, I.1
Thevenot, G.2
Bedouet, L.3
Danel, C.4
Riquet, M.5
Merten, M.6
Figarella, C.7
Dall'Ava-Santucci, J.8
Monsigny, M.9
Briand, P.10
-
43
-
-
5644236707
-
Lactosylated polyethylenimine for gene transfer into airway epithelial cells: Role of the sugar moiety in cell delivery and intracellular trafficking of the complexes
-
S. Grosse, Y. Aron, I. Honore, G. Thevenot, C. Danel, A.C. Roche, M. Monsigny, and I. Fajac Lactosylated polyethylenimine for gene transfer into airway epithelial cells: role of the sugar moiety in cell delivery and intracellular trafficking of the complexes J. Gene Med. 6 3 2004 345 356
-
(2004)
J. Gene Med.
, vol.6
, Issue.3
, pp. 345-356
-
-
Grosse, S.1
Aron, Y.2
Honore, I.3
Thevenot, G.4
Danel, C.5
Roche, A.C.6
Monsigny, M.7
Fajac, I.8
-
44
-
-
56649121906
-
In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments
-
S. Grosse, G. Thevenot, Y. Aron, E. Duverger, M. Abdelkarim, A.C. Roche, M. Monsigny, and I. Fajac In vivo gene delivery in the mouse lung with lactosylated polyethylenimine, questioning the relevance of in vitro experiments J. Control. Release 132 2 2008 105 112
-
(2008)
J. Control. Release
, vol.132
, Issue.2
, pp. 105-112
-
-
Grosse, S.1
Thevenot, G.2
Aron, Y.3
Duverger, E.4
Abdelkarim, M.5
Roche, A.C.6
Monsigny, M.7
Fajac, I.8
-
45
-
-
0037436017
-
Galactose-PEI-DNA complexes for targeted gene delivery: Degree of substitution affects complex size and transfection efficiency
-
K. Kunath, A. von Harpe, D. Fischer, and T. Kissel Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency J. Control. Release 88 1 2003 159 172
-
(2003)
J. Control. Release
, vol.88
, Issue.1
, pp. 159-172
-
-
Kunath, K.1
Von Harpe, A.2
Fischer, D.3
Kissel, T.4
-
46
-
-
20444426861
-
Galactosylated polyethylenimine-graft-poly(vinyl pyrrolidone) as a hepatocyte-targeting gene carrier
-
S.E. Cook, I.K. Park, E.M. Kim, H.J. Jeong, T.G. Park, Y.J. Choi, T. Akaike, and C.S. Cho Galactosylated polyethylenimine-graft-poly(vinyl pyrrolidone) as a hepatocyte-targeting gene carrier J. Control. Release 105 1-2 2005 151 163
-
(2005)
J. Control. Release
, vol.105
, Issue.12
, pp. 151-163
-
-
Cook, S.E.1
Park, I.K.2
Kim, E.M.3
Jeong, H.J.4
Park, T.G.5
Choi, Y.J.6
Akaike, T.7
Cho, C.S.8
-
47
-
-
50849092852
-
Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer
-
J. Chen, X. Gao, K. Hu, Z. Pang, J. Cai, J. Li, H. Wu, and X. Jiang Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer Biochem. Biophys. Res. Commun. 375 3 2008 378 383
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.375
, Issue.3
, pp. 378-383
-
-
Chen, J.1
Gao, X.2
Hu, K.3
Pang, Z.4
Cai, J.5
Li, J.6
Wu, H.7
Jiang, X.8
-
48
-
-
66149138398
-
Hyperbranched PEI with various oligosaccharide architectures: Synthesis, characterization, ATP complexation, and cellular uptake properties
-
D. Appelhans, H. Komber, M.A. Quadir, S. Richter, S. Schwarz, J. van der Vlist, A. Aigner, M. Muller, K. Loos, J. Seidel, K.F. Arndt, R. Haag, and B. Voit Hyperbranched PEI with various oligosaccharide architectures: synthesis, characterization, ATP complexation, and cellular uptake properties Biomacromolecules 10 5 2009 1114 1124
-
(2009)
Biomacromolecules
, vol.10
, Issue.5
, pp. 1114-1124
-
-
Appelhans, D.1
Komber, H.2
Quadir, M.A.3
Richter, S.4
Schwarz, S.5
Van Der Vlist, J.6
Aigner, A.7
Muller, M.8
Loos, K.9
Seidel, J.10
Arndt, K.F.11
Haag, R.12
Voit, B.13
-
49
-
-
0033122034
-
Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI)
-
P. Erbacher, T. Bettinger, P. Belguise-Valladier, S. Zou, J.L. Coll, J.P. Behr, and J.S. Remy Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI) J. Gene Med. 1 3 1999 210 222
-
(1999)
J. Gene Med.
, vol.1
, Issue.3
, pp. 210-222
-
-
Erbacher, P.1
Bettinger, T.2
Belguise-Valladier, P.3
Zou, S.4
Coll, J.L.5
Behr, J.P.6
Remy, J.S.7
-
50
-
-
55349124000
-
Synthesis of branched polyglucans by the tandem action of potato phosphorylase and Deinococcus geothermalis glycogen branching enzyme
-
J. van der Vlist, M. Palomo Reixach, M. van der Maarel, L. Dijkhuizen, A.J. Schouten, and K. Loos Synthesis of branched polyglucans by the tandem action of potato phosphorylase and Deinococcus geothermalis glycogen branching enzyme Macromol. Rapid Commun. 29 2008 1293 1297
-
(2008)
Macromol. Rapid Commun.
, vol.29
, pp. 1293-1297
-
-
Van Der Vlist, J.1
Palomo Reixach, M.2
Van Der Maarel, M.3
Dijkhuizen, L.4
Schouten, A.J.5
Loos, K.6
-
51
-
-
0028997949
-
In vitro cytotoxicity of macromolecules in different cell culture systems
-
S. Choksakulnimitr, S. Masuda, H. Tokuda, Y. Takakura, and M. Hashida In vitro cytotoxicity of macromolecules in different cell culture systems J. Control. Release 34 1995 233 241
-
(1995)
J. Control. Release
, vol.34
, pp. 233-241
-
-
Choksakulnimitr, S.1
Masuda, S.2
Tokuda, H.3
Takakura, Y.4
Hashida, M.5
-
52
-
-
34247563782
-
Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine
-
K. Remaut, B. Lucas, K. Raemdonck, K. Braeckmans, J. Demeester, and S.C. De Smedt Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegylated branched polyethyleneimine Biomacromolecules 8 4 2007 1333 1340
-
(2007)
Biomacromolecules
, vol.8
, Issue.4
, pp. 1333-1340
-
-
Remaut, K.1
Lucas, B.2
Raemdonck, K.3
Braeckmans, K.4
Demeester, J.5
De Smedt, S.C.6
-
53
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
S.M. Hammond, E. Bernstein, D. Beach, and G.J. Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells Nature 404 6775 2000 293 296
-
(2000)
Nature
, vol.404
, Issue.6775
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
54
-
-
33947572267
-
Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy
-
S. Srinivasachari, Y. Liu, L.E. Prevette, and T.M. Reineke Effects of trehalose click polymer length on pDNA complex stability and delivery efficacy Biomaterials 28 18 2007 2885 2898
-
(2007)
Biomaterials
, vol.28
, Issue.18
, pp. 2885-2898
-
-
Srinivasachari, S.1
Liu, Y.2
Prevette, L.E.3
Reineke, T.M.4
-
55
-
-
77955879616
-
Polycation cytotoxicity: A delicate matter for nucleic acid therapy - Focus on polyethylenimine
-
L. Parhamifar, A.K. Larsen, A.C. Hunter, T.L. Andresen, and S.M. Moghimi Polycation cytotoxicity: a delicate matter for nucleic acid therapy - focus on polyethylenimine Soft Matter 6 2010 4001 4009
-
(2010)
Soft Matter
, vol.6
, pp. 4001-4009
-
-
Parhamifar, L.1
Larsen, A.K.2
Hunter, A.C.3
Andresen, T.L.4
Moghimi, S.M.5
-
56
-
-
0035184233
-
Biological basket weaving: Formation and function of clathrin-coated vesicles
-
F.M. Brodsky, C.Y. Chen, C. Knuehl, M.C. Towler, and D.E. Wakeham Biological basket weaving: formation and function of clathrin-coated vesicles Annu. Rev. Cell Dev. Biol. 17 2001 517 568
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 517-568
-
-
Brodsky, F.M.1
Chen, C.Y.2
Knuehl, C.3
Towler, M.C.4
Wakeham, D.E.5
-
57
-
-
0027520440
-
Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
-
L.H. Wang, K.G. Rothberg, and R.G. Anderson Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation J. Cell Biol. 123 5 1993 1107 1117
-
(1993)
J. Cell Biol.
, vol.123
, Issue.5
, pp. 1107-1117
-
-
Wang, L.H.1
Rothberg, K.G.2
Anderson, R.G.3
-
58
-
-
0022899025
-
Potassium-dependent assembly of coated pits: New coated pits form as planar clathrin lattices
-
J.M. Larkin, W.C. Donzell, and R.G. Anderson Potassium-dependent assembly of coated pits: new coated pits form as planar clathrin lattices J. Cell Biol. 103 6 Pt 2 1986 2619 2627
-
(1986)
J. Cell Biol.
, vol.103
, Issue.6 PART 2
, pp. 2619-2627
-
-
Larkin, J.M.1
Donzell, W.C.2
Anderson, R.G.3
-
59
-
-
77649272916
-
The use of inhibitors to study endocytic pathways of gene carriers: Optimization and pitfalls
-
D. Vercauteren, R.E. Vandenbroucke, A.T. Jones, J. Rejman, J. Demeester, S.C. De Smedt, N.N. Sanders, and K. Braeckmans The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls Mol. Ther. 18 3 2010 561 569
-
(2010)
Mol. Ther.
, vol.18
, Issue.3
, pp. 561-569
-
-
Vercauteren, D.1
Vandenbroucke, R.E.2
Jones, A.T.3
Rejman, J.4
Demeester, J.5
De Smedt, S.C.6
Sanders, N.N.7
Braeckmans, K.8
-
60
-
-
0031750101
-
Filipin-dependent inhibition of cholera toxin: Evidence for toxin internalization and activation through caveolae-like domains
-
P.A. Orlandi, and P.H. Fishman Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains J. Cell Biol. 141 4 1998 905 915
-
(1998)
J. Cell Biol.
, vol.141
, Issue.4
, pp. 905-915
-
-
Orlandi, P.A.1
Fishman, P.H.2
-
61
-
-
0028138521
-
Regulated internalization of caveolae
-
R.G. Parton, B. Joggerst, and K. Simons Regulated internalization of caveolae J. Cell Biol. 127 5 1994 1199 1215
-
(1994)
J. Cell Biol.
, vol.127
, Issue.5
, pp. 1199-1215
-
-
Parton, R.G.1
Joggerst, B.2
Simons, K.3
-
62
-
-
0037684840
-
Caveolae/raft-dependent endocytosis
-
I.R. Nabi, and P.U. Le Caveolae/raft-dependent endocytosis J. Cell Biol. 161 4 2003 673 677
-
(2003)
J. Cell Biol.
, vol.161
, Issue.4
, pp. 673-677
-
-
Nabi, I.R.1
Le, P.U.2
-
63
-
-
33749247082
-
The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type
-
K. von Gersdorff, N.N. Sanders, R. Vandenbroucke, S.C. De Smedt, E. Wagner, and M. Ogris The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type Mol. Ther. 14 5 2006 745 753
-
(2006)
Mol. Ther.
, vol.14
, Issue.5
, pp. 745-753
-
-
Von Gersdorff, K.1
Sanders, N.N.2
Vandenbroucke, R.3
De Smedt, S.C.4
Wagner, E.5
Ogris, M.6
-
64
-
-
77349095284
-
Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab
-
S. Hobel, I. Koburger, M. John, F. Czubayko, P. Hadwiger, H.P. Vornlocher, and A. Aigner Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab J. Gene Med. 12 3 2010 287 300
-
(2010)
J. Gene Med.
, vol.12
, Issue.3
, pp. 287-300
-
-
Hobel, S.1
Koburger, I.2
John, M.3
Czubayko, F.4
Hadwiger, P.5
Vornlocher, H.P.6
Aigner, A.7
-
65
-
-
34447281239
-
RNA interference targeting hypoxia inducible factor 1alpha reduces post-operative adhesions in rats
-
T. Segura, H. Schmokel, and J.A. Hubbell RNA interference targeting hypoxia inducible factor 1alpha reduces post-operative adhesions in rats J. Surg. Res. 141 2 2007 162 170
-
(2007)
J. Surg. Res.
, vol.141
, Issue.2
, pp. 162-170
-
-
Segura, T.1
Schmokel, H.2
Hubbell, J.A.3
-
66
-
-
33947302736
-
Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy
-
W.J. Kim, C.W. Chang, M. Lee, and S.W. Kim Efficient siRNA delivery using water soluble lipopolymer for anti-angiogenic gene therapy J. Control. Release 118 3 2007 357 363
-
(2007)
J. Control. Release
, vol.118
, Issue.3
, pp. 357-363
-
-
Kim, W.J.1
Chang, C.W.2
Lee, M.3
Kim, S.W.4
-
67
-
-
72149101228
-
The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine
-
A. Alshamsan, S. Hamdy, J. Samuel, A.O. El-Kadi, A. Lavasanifar, and H. Uludag The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine Biomaterials 31 6 2010 1420 1428
-
(2010)
Biomaterials
, vol.31
, Issue.6
, pp. 1420-1428
-
-
Alshamsan, A.1
Hamdy, S.2
Samuel, J.3
El-Kadi, A.O.4
Lavasanifar, A.5
Uludag, H.6
-
68
-
-
68849112640
-
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity
-
J.R. Cubillos-Ruiz, X. Engle, U.K. Scarlett, D. Martinez, A. Barber, R. Elgueta, L. Wang, Y. Nesbeth, Y. Durant, A.T. Gewirtz, C.L. Sentman, R. Kedl, and J.R. Conejo-Garcia Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity J. Clin. Invest. 119 8 2009 2231 2244
-
(2009)
J. Clin. Invest.
, vol.119
, Issue.8
, pp. 2231-2244
-
-
Cubillos-Ruiz, J.R.1
Engle, X.2
Scarlett, U.K.3
Martinez, D.4
Barber, A.5
Elgueta, R.6
Wang, L.7
Nesbeth, Y.8
Durant, Y.9
Gewirtz, A.T.10
Sentman, C.L.11
Kedl, R.12
Conejo-Garcia, J.R.13
-
69
-
-
14544298301
-
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle
-
R.M. Schiffelers, A. Ansari, J. Xu, Q. Zhou, Q. Tang, G. Storm, G. Molema, P.Y. Lu, P.V. Scaria, and M.C. Woodle Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle Nucleic Acids Res. 32 19 2004 e149
-
(2004)
Nucleic Acids Res.
, vol.32
, Issue.19
, pp. 149
-
-
Schiffelers, R.M.1
Ansari, A.2
Xu, J.3
Zhou, Q.4
Tang, Q.5
Storm, G.6
Molema, G.7
Lu, P.Y.8
Scaria, P.V.9
Woodle, M.C.10
-
70
-
-
33846821991
-
Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration
-
H.K. de Wolf, C.J. Snel, F.J. Verbaan, R.M. Schiffelers, W.E. Hennink, and G. Storm Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration Int. J. Pharm. 331 2 2007 167 175
-
(2007)
Int. J. Pharm.
, vol.331
, Issue.2
, pp. 167-175
-
-
De Wolf, H.K.1
Snel, C.J.2
Verbaan, F.J.3
Schiffelers, R.M.4
Hennink, W.E.5
Storm, G.6
-
71
-
-
68249122805
-
Nonviral siRNA delivery to the lung: Investigation of PEG-PEI polyplexes and their in vivo performance
-
O.M. Merkel, A. Beyerle, D. Librizzi, A. Pfestroff, T.M. Behr, B. Sproat, P.J. Barth, and T. Kissel Nonviral siRNA delivery to the lung: investigation of PEG-PEI polyplexes and their in vivo performance Mol. Pharm. 6 4 2009 1246 1260
-
(2009)
Mol. Pharm.
, vol.6
, Issue.4
, pp. 1246-1260
-
-
Merkel, O.M.1
Beyerle, A.2
Librizzi, D.3
Pfestroff, A.4
Behr, T.M.5
Sproat, B.6
Barth, P.J.7
Kissel, T.8
-
72
-
-
67651202350
-
Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
-
O.M. Merkel, D. Librizzi, A. Pfestroff, T. Schurrat, K. Buyens, N.N. Sanders, S.C. De Smedt, M. Behe, and T. Kissel Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging J. Control. Release 138 2 2009 148 159
-
(2009)
J. Control. Release
, vol.138
, Issue.2
, pp. 148-159
-
-
Merkel, O.M.1
Librizzi, D.2
Pfestroff, A.3
Schurrat, T.4
Buyens, K.5
Sanders, N.N.6
De Smedt, S.C.7
Behe, M.8
Kissel, T.9
|