Multifunctional hierarchically assembled nanostructures as complex stage-wise dual-delivery systems for coincidental yet differential trafficking of siRNA and paclitaxel

Nano Letters

Volumn 13, Issue 5, 2013, Pages 2172-2181

  Elsabahy, Mahmoud ^a,b   Shrestha, Ritu ^a   Clark, Corrie ^a   Taylor, Sara ^c   Leonard, Jeffrey ^c   Wooley, Karen L ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b Assiut University   (Egypt)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

combinational therapy; cylindrical nanoparticles; immunotoxicity; intracellular delivery mechanisms; Multifunctional shell cross linked nanoparticles; nanoparticle shape; paclitaxel; siRNA; theranostics

Indexed keywords

COMBINATIONAL THERAPY; IMMUNOTOXICITY; INTRACELLULAR DELIVERY; NANOPARTICLE SHAPE; PACLITAXEL; SHELL CROSS-LINKED NANOPARTICLES; SIRNA; THERANOSTICS;

CELL CULTURE; CELL DEATH; CELL MEMBRANES; CYLINDERS (SHAPES); HYDROPHOBICITY; LIPOSOMES; NANOPARTICLES; NUCLEIC ACIDS; SPHERES;

GENE THERAPY;

NANOMATERIAL; PACLITAXEL; SMALL INTERFERING RNA;

ANIMAL; ARTICLE; CELL DEATH; CELL LINE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; MACROPHAGE; MOUSE; STRUCTURE ACTIVITY RELATION; DRUG EFFECTS;

ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; HUMANS; MACROPHAGES; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NANOSTRUCTURES; PACLITAXEL; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84877301967     PISSN: 15306984     EISSN: 15306992     Source Type: Journal    
DOI: 10.1021/nl4006645     Document Type: Article

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